Gene description for THBD
Gene name	thrombomodulin
Gene symbol	THBD
Other names/aliases	AHUS6 BDCA-3 BDCA3 CD141 THPH12 THRM TM
Species	Homo sapiens
Experiment description of studies that identified THBD in Endothelial cells
1 Experiment ID 223 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 10393703    Organism Homo sapiens Experiment description In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Authors Combes V, Simon AC, Grau GE, Arnoux D, Camoin L, Sabatier F, Mutin M, Sanmarco M, Sampol J, Dignat-George F Journal name J Clin Invest Publication year 1999 Sample Endothelial cells Sample name HUVECS Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study FACS Western blotting EV-TRACK -
2 Experiment ID 551 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 24009886    Organism Homo sapiens Experiment description Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Authors de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. Journal name J Extracell Vesicles Publication year 2012 Sample Endothelial cells Sample name Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120004: EV-METRIC:67%