Gene description for CD9
Gene name CD9 molecule
Gene symbol CD9
Other names/aliases BTCC-1
DRAP-27
MIC3
MRP-1
TSPAN-29
TSPAN29
Species Homo sapiens
 Experiment description of studies that identified CD9 in Serum

1
Experiment ID111
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 21601258   
OrganismHomo sapiens
Experiment descriptionLoss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.
AuthorsRupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P.
Journal name GO
Publication year2011
SampleSerum
Sample nameSerum - breast cancer
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Immunobeads (CD24)
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
EV-TRACK EV110020: EV-METRIC:13%, 63%, 50%

2
Experiment ID112
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 21601258   
OrganismHomo sapiens
Experiment descriptionLoss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.
AuthorsRupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P.
Journal name GO
Publication year2011
SampleSerum
Sample nameSerum - Normal
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
EV-TRACK EV110020: EV-METRIC:13%, 63%, 50%

3
Experiment ID965
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 25844599   
OrganismHomo sapiens
Experiment descriptionMolecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
AuthorsKharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year2015
SampleSerum
Sample namecastration resistant prostate cancer patient - R1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV150027: EV-METRIC:11%, 56%

4
Experiment ID966
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 25844599   
OrganismHomo sapiens
Experiment descriptionMolecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
AuthorsKharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year2015
SampleSerum
Sample namecastration resistant prostate cancer patient - R2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV150027: EV-METRIC:11%, 56%

5
Experiment ID967
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 25844599   
OrganismHomo sapiens
Experiment descriptionMolecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
AuthorsKharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year2015
SampleSerum
Sample namecastration resistant prostate cancer patient - R3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV150027: EV-METRIC:11%, 56%

6
Experiment ID970
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 25844599   
OrganismHomo sapiens
Experiment descriptionMolecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
AuthorsKharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year2015
SampleSerum
Sample namecastration resistant prostate cancer patient - S6
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV150027: EV-METRIC:11%, 56%

7
Experiment ID1203
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 27780738   
OrganismHomo sapiens
Experiment descriptionNext-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.
AuthorsYagi Y, Ohkubo T, Kawaji H, Machida A, Miyata H, Goda S, Roy S, Hayashizaki Y, Suzuki H, Yokota T.
Journal name Neurosci Lett.
Publication year2017
SampleSerum
Sample nameHealthy donor 1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studymiRNA
Methods used in the studyNext generation sequencing
EV-TRACK -

8
Experiment ID1501
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameHealthy volunteers
Isolation/purification methodsExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qRT-PCR
EV-TRACK -

9
Experiment ID1502
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Tryptase <110 ng/mL
Isolation/purification methodsExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qRT-PCR
EV-TRACK -

10
Experiment ID1503
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Tryptase >110 ng/mL
Isolation/purification methodsExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qRT-PCR
EV-TRACK -

11
Experiment ID1504
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameHealthy volunteers - Pooled
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

12
Experiment ID1505
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Tryptase <110 ng/mL - Pooled
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

13
Experiment ID1506
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Tryptase >110 ng/mL - Pooled
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

14
Experiment ID1509
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 3
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

15
Experiment ID1510
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 4
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

16
Experiment ID1511
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 5
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

17
Experiment ID1512
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 6
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

18
Experiment ID2007
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Flow cytometry
PubMed ID 35979935   
OrganismHomo sapiens
Experiment descriptionSerum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients
AuthorsTertel T, Tomić S, Đokić J, Radojević D, Stevanović D, Ilić N, Giebel B, Kosanović M.
Journal name J Extracell Vesicles
Publication year2022
SampleSerum
Sample nameHealthy donors
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyFlow cytometry
EV-TRACK -

19
Experiment ID2008
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Flow cytometry
PubMed ID 35979935   
OrganismHomo sapiens
Experiment descriptionSerum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients
AuthorsTertel T, Tomić S, Đokić J, Radojević D, Stevanović D, Ilić N, Giebel B, Kosanović M.
Journal name J Extracell Vesicles
Publication year2022
SampleSerum
Sample nameSevere COVID-19 patients
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyFlow cytometry
EV-TRACK -

20
Experiment ID2009
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Flow cytometry
PubMed ID 35979935   
OrganismHomo sapiens
Experiment descriptionSerum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients
AuthorsTertel T, Tomić S, Đokić J, Radojević D, Stevanović D, Ilić N, Giebel B, Kosanović M.
Journal name J Extracell Vesicles
Publication year2022
SampleSerum
Sample nameMild COVID-19 patients
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyFlow cytometry
EV-TRACK -

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