Gene description for CD63 |
Gene name |
CD63 molecule |
Gene symbol |
CD63 |
Other names/aliases |
AD1 HOP-26 ME491 MLA1 OMA81H Pltgp40 TSPAN30 |
Species |
Homo sapiens |
Experiment description of studies that identified CD63 in Platelets |
1
|
Experiment ID | 31 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | FACS Immunoelectron Microscopy
|
PubMed ID |
10572093
|
Organism | Homo sapiens |
Experiment description | Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. |
Authors | Heijnen HF, Schiel AE, Fijnheer R, Geuze HJ, Sixma JJ |
Journal name |
BLOOD
|
Publication year | 1999 |
Sample | Platelets |
Sample name | Platelets |
Isolation/purification methods | Differential centrifugation Sucrose density gradient |
Flotation density | 1.14-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting FACS Immunoelectron microscopy |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 1344 |
Identified molecule | protein
|
Extracellular vesicle type | Platelet-derived microparticles |
MISEV | EV-like nanoparticles |
Identification method | Western blotting
|
PubMed ID |
33009394
|
Organism | Homo sapiens |
Experiment description | Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p |
Authors | Qu M, Zou X, Fang F, Wang S, Xu L, Zeng Q, Fan Z, Chen L, Yue W, Xie X, Pei X. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Platelets |
Sample name | Platelets derived from umbilical cord blood |
Isolation/purification methods | Ficoll-Hypaque density gradient centrifugation Differential centrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Flow cytometry Western blotting qPCR |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 3504 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Western blotting
|
PubMed ID |
31160588
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
Authors | Sung PS, Huang TF, Hsieh SL. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Platelets |
Sample name | Peripheral blood of healthy donors |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 3505 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Western blotting
|
PubMed ID |
31160588
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
Authors | Sung PS, Huang TF, Hsieh SL. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Platelets |
Sample name | Peripheral blood of healthy donors |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 3495 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Flow cytometryWestern blotting
|
PubMed ID |
31160588
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
Authors | Sung PS, Huang TF, Hsieh SL. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Platelets |
Sample name | Peripheral blood of healthy donors |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Flow cytometry |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 3498 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Flow cytometry Western blotting
|
PubMed ID |
31160588
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
Authors | Sung PS, Huang TF, Hsieh SL. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Platelets |
Sample name | Peripheral blood of healthy donors |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Flow cytometry |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 3496 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Flow cytometry
|
PubMed ID |
31160588
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
Authors | Sung PS, Huang TF, Hsieh SL. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Platelets |
Sample name | Peripheral blood of healthy donors |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Flow cytometry |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 3497 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Flow cytometry
|
PubMed ID |
31160588
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
Authors | Sung PS, Huang TF, Hsieh SL. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Platelets |
Sample name | Peripheral blood of healthy donors |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Flow cytometry |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 3499 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Flow cytometry
|
PubMed ID |
31160588
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
Authors | Sung PS, Huang TF, Hsieh SL. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Platelets |
Sample name | Peripheral blood of healthy donors |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Flow cytometry |
EV-TRACK |
-
|
|
|
10
|
Experiment ID | 3500 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Flow cytometry
|
PubMed ID |
31160588
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
Authors | Sung PS, Huang TF, Hsieh SL. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Platelets |
Sample name | Peripheral blood of healthy donors |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Flow cytometry |
EV-TRACK |
-
|
|
|
11
|
Experiment ID | 3501 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Flow cytometry
|
PubMed ID |
31160588
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
Authors | Sung PS, Huang TF, Hsieh SL. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Platelets |
Sample name | Peripheral blood of healthy donors |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Flow cytometry |
EV-TRACK |
-
|
|
|
12
|
Experiment ID | 3502 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Flow cytometry
|
PubMed ID |
31160588
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
Authors | Sung PS, Huang TF, Hsieh SL. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Platelets |
Sample name | Peripheral blood of healthy donors |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Flow cytometry |
EV-TRACK |
-
|
|
|
13
|
Experiment ID | 3503 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Flow cytometry
|
PubMed ID |
31160588
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
Authors | Sung PS, Huang TF, Hsieh SL. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Platelets |
Sample name | Peripheral blood of healthy donors |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Flow cytometry |
EV-TRACK |
-
|
|
|