Gene description for CD63 |
| Gene name |
CD63 molecule |
| Gene symbol |
CD63 |
| Other names/aliases |
AD1 HOP-26 ME491 MLA1 OMA81H Pltgp40 TSPAN30 |
| Species |
Homo sapiens |
Experiment description of studies that identified CD63 in Platelets |
| 1
|
| Experiment ID | 31 |
| Identified molecule | protein
|
| Extracellular vesicle type | Exosomes |
| MISEV | EVs |
| Identification method | FACS Immunoelectron Microscopy
|
| PubMed ID |
10572093
|
| Organism | Homo sapiens |
| Experiment description | Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. |
| Authors | Heijnen HF, Schiel AE, Fijnheer R, Geuze HJ, Sixma JJ |
| Journal name |
BLOOD
|
| Publication year | 1999 |
| Sample | Platelets |
| Sample name | Platelets |
| Isolation/purification methods | Differential centrifugation Sucrose density gradient |
| Flotation density | 1.14-1.18 g/mL |
| Molecules identified in the study | Protein |
| Methods used in the study | Western blotting FACS Immunoelectron microscopy |
| EV-TRACK |
-
|
|
|
| 2
|
| Experiment ID | 1344 |
| Identified molecule | protein
|
| Extracellular vesicle type | Platelet-derived microparticles |
| MISEV | EV-like nanoparticles |
| Identification method | Western blotting
|
| PubMed ID |
33009394
|
| Organism | Homo sapiens |
| Experiment description | Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p |
| Authors | Qu M, Zou X, Fang F, Wang S, Xu L, Zeng Q, Fan Z, Chen L, Yue W, Xie X, Pei X. |
| Journal name |
Nat Commun
|
| Publication year | 2020 |
| Sample | Platelets |
| Sample name | Platelets derived from umbilical cord blood |
| Isolation/purification methods | Ficoll-Hypaque density gradient centrifugation Differential centrifugation Filtration |
| Flotation density | - |
| Molecules identified in the study | Protein miRNA |
| Methods used in the study | Flow cytometry Western blotting qPCR |
| EV-TRACK |
-
|
|
|
| 3
|
| Experiment ID | 3504 |
| Identified molecule | protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | EVs |
| Identification method | Western blotting
|
| PubMed ID |
31160588
|
| Organism | Homo sapiens |
| Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
| Authors | Sung PS, Huang TF, Hsieh SL. |
| Journal name |
Nat Commun
|
| Publication year | 2019 |
| Sample | Platelets |
| Sample name | Peripheral blood of healthy donors |
| Isolation/purification methods | Differential centrifugation |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Western blotting |
| EV-TRACK |
-
|
|
|
| 4
|
| Experiment ID | 3505 |
| Identified molecule | protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | EVs |
| Identification method | Western blotting
|
| PubMed ID |
31160588
|
| Organism | Homo sapiens |
| Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
| Authors | Sung PS, Huang TF, Hsieh SL. |
| Journal name |
Nat Commun
|
| Publication year | 2019 |
| Sample | Platelets |
| Sample name | Peripheral blood of healthy donors |
| Isolation/purification methods | Differential centrifugation |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Western blotting |
| EV-TRACK |
-
|
|
|
| 5
|
| Experiment ID | 3495 |
| Identified molecule | protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | EVs |
| Identification method | Flow cytometryWestern blotting
|
| PubMed ID |
31160588
|
| Organism | Homo sapiens |
| Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
| Authors | Sung PS, Huang TF, Hsieh SL. |
| Journal name |
Nat Commun
|
| Publication year | 2019 |
| Sample | Platelets |
| Sample name | Peripheral blood of healthy donors |
| Isolation/purification methods | Differential centrifugation |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Western blotting Flow cytometry |
| EV-TRACK |
-
|
|
|
| 6
|
| Experiment ID | 3498 |
| Identified molecule | protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | EVs |
| Identification method | Flow cytometry Western blotting
|
| PubMed ID |
31160588
|
| Organism | Homo sapiens |
| Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
| Authors | Sung PS, Huang TF, Hsieh SL. |
| Journal name |
Nat Commun
|
| Publication year | 2019 |
| Sample | Platelets |
| Sample name | Peripheral blood of healthy donors |
| Isolation/purification methods | Differential centrifugation |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Western blotting Flow cytometry |
| EV-TRACK |
-
|
|
|
| 7
|
| Experiment ID | 3496 |
| Identified molecule | protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | EVs |
| Identification method | Flow cytometry
|
| PubMed ID |
31160588
|
| Organism | Homo sapiens |
| Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
| Authors | Sung PS, Huang TF, Hsieh SL. |
| Journal name |
Nat Commun
|
| Publication year | 2019 |
| Sample | Platelets |
| Sample name | Peripheral blood of healthy donors |
| Isolation/purification methods | Differential centrifugation |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Flow cytometry |
| EV-TRACK |
-
|
|
|
| 8
|
| Experiment ID | 3497 |
| Identified molecule | protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | EVs |
| Identification method | Flow cytometry
|
| PubMed ID |
31160588
|
| Organism | Homo sapiens |
| Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
| Authors | Sung PS, Huang TF, Hsieh SL. |
| Journal name |
Nat Commun
|
| Publication year | 2019 |
| Sample | Platelets |
| Sample name | Peripheral blood of healthy donors |
| Isolation/purification methods | Differential centrifugation |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Flow cytometry |
| EV-TRACK |
-
|
|
|
| 9
|
| Experiment ID | 3499 |
| Identified molecule | protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | EVs |
| Identification method | Flow cytometry
|
| PubMed ID |
31160588
|
| Organism | Homo sapiens |
| Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
| Authors | Sung PS, Huang TF, Hsieh SL. |
| Journal name |
Nat Commun
|
| Publication year | 2019 |
| Sample | Platelets |
| Sample name | Peripheral blood of healthy donors |
| Isolation/purification methods | Differential centrifugation |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Flow cytometry |
| EV-TRACK |
-
|
|
|
| 10
|
| Experiment ID | 3500 |
| Identified molecule | protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | EVs |
| Identification method | Flow cytometry
|
| PubMed ID |
31160588
|
| Organism | Homo sapiens |
| Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
| Authors | Sung PS, Huang TF, Hsieh SL. |
| Journal name |
Nat Commun
|
| Publication year | 2019 |
| Sample | Platelets |
| Sample name | Peripheral blood of healthy donors |
| Isolation/purification methods | Differential centrifugation |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Flow cytometry |
| EV-TRACK |
-
|
|
|
| 11
|
| Experiment ID | 3501 |
| Identified molecule | protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | EVs |
| Identification method | Flow cytometry
|
| PubMed ID |
31160588
|
| Organism | Homo sapiens |
| Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
| Authors | Sung PS, Huang TF, Hsieh SL. |
| Journal name |
Nat Commun
|
| Publication year | 2019 |
| Sample | Platelets |
| Sample name | Peripheral blood of healthy donors |
| Isolation/purification methods | Differential centrifugation |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Flow cytometry |
| EV-TRACK |
-
|
|
|
| 12
|
| Experiment ID | 3502 |
| Identified molecule | protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | EVs |
| Identification method | Flow cytometry
|
| PubMed ID |
31160588
|
| Organism | Homo sapiens |
| Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
| Authors | Sung PS, Huang TF, Hsieh SL. |
| Journal name |
Nat Commun
|
| Publication year | 2019 |
| Sample | Platelets |
| Sample name | Peripheral blood of healthy donors |
| Isolation/purification methods | Differential centrifugation |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Flow cytometry |
| EV-TRACK |
-
|
|
|
| 13
|
| Experiment ID | 3503 |
| Identified molecule | protein
|
| Extracellular vesicle type | Extracellular vesicles |
| MISEV | EVs |
| Identification method | Flow cytometry
|
| PubMed ID |
31160588
|
| Organism | Homo sapiens |
| Experiment description | Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 |
| Authors | Sung PS, Huang TF, Hsieh SL. |
| Journal name |
Nat Commun
|
| Publication year | 2019 |
| Sample | Platelets |
| Sample name | Peripheral blood of healthy donors |
| Isolation/purification methods | Differential centrifugation |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Flow cytometry |
| EV-TRACK |
-
|
|
|