Gene description for ANXA1
Gene name annexin A1
Gene symbol ANXA1
Other names/aliases ANX1
LPC1
Species Homo sapiens
 Database cross references - ANXA1
Vesiclepedia VP_301
ExoCarta ExoCarta_301
Entrez Gene 301
HGNC 533
MIM 151690
 ANXA1 identified in extracellular vesicles derived from the following tissue/cell type
Amniotic fluid [Exosomes]      More >>> 17700640   
Aqueous humor [Exosomes]      More >>> 21362503   
Ascites [Exosomes]      More >>> 21601258   
Ascites [Exosomes]      More >>> 21601258   
Ascites [Exosomes]      More >>> 19188015   
Ascites [Microvesicles]      More >>> 21630462   
Ascites [Microvesicles]      More >>> 21630462   
Ascites [Microvesicles]      More >>> 21630462   
Astrocytoma cells [Extracellular vesicles]      More >>> 30006486   
Astrocytoma cells [Extracellular vesicles]      More >>> 30006486   
Astrocytoma cells [Extracellular vesicles]      More >>> 30006486   
Astrocytoma cells [Extracellular vesicles]      More >>> 30006486   
Astrocytoma cells [Extracellular vesicles]      More >>> 30006486   
Astrocytoma cells [Extracellular vesicles]      More >>> 30006486   
B cells [Microparticles]      More >>> 19413345   
B cells [Microparticles]      More >>> 19413345   
B cells [Microparticles]      More >>> 19413345   
Bladder cancer cells [Exosomes]      More >>> 20224111   
Bladder cancer cells [Extracellular vesicles]      More >>> 29207636   
Bladder cancer cells [Extracellular vesicles]      More >>> 29207636   
Bovine milk [Exosomes]      More >>> 28290293   
Bovine milk [Exosomes]      More >>> 28290293   
Brain cancer cells [Extracellular vesicles]      More >>> 27894104   
Brain cancer cells [Extracellular vesicles]      More >>> 27894104   
Breast cancer cells [Extracellular vesicles]      More >>> 27894104   
Breast cancer cells [Extracellular vesicles]      More >>> 27894104   
Breast cancer cells [Extracellular vesicles]      More >>> 22399603   
Breast cancer cells [Extracellular vesicles]      More >>> 24468161   
Breast milk [Extracellular vesicles]      More >>> 27601599   
Breast milk [Exosomes]      More >>> 28290293   
Breast milk [Exosomes]      More >>> 28290293   
Breast milk [Extracellular vesicles]      More >>> 27601599   
Breast milk [Extracellular vesicles]      More >>> 27601599   
Breast milk [Extracellular vesicles]      More >>> 27601599   
Breast milk [Extracellular vesicles]      More >>> 27601599   
Breast milk [Extracellular vesicles]      More >>> 27601599   
Breast milk [Extracellular vesicles]      More >>> 27601599   
Bronchial epithelial cells [Extracellular vesicles]      More >>> 29127410   
Bronchial epithelial cells [Extracellular vesicles]      More >>> 29127410   
Bronchial epithelial cells [Extracellular vesicles]      More >>> 29127410   
Bronchial epithelial cells [Extracellular vesicles]      More >>> 29127410   
Bronchial epithelial cells [Extracellular vesicles]      More >>> 29127410   
Bronchial epithelial cells [Extracellular vesicles]      More >>> 29127410   
Bronchial epithelial cells [Extracellular vesicles]      More >>> 29127410   
Bronchial epithelial cells [Extracellular vesicles]      More >>> 29127410   
Carotid atherosclerotic plaques [Microparticles]      More >>> 20031610   
Carotid atherosclerotic plaques [Microparticles]      More >>> 20031610   
Cholangiocarcinoma cells [Exosomes]      More >>> 26148937   
Chronic lymphocytic leukemia cells [Exosomes]      More >>> 26100252   
Chronic lymphocytic leukemia cells [Exosomes]      More >>> 26100252   
Chronic lymphocytic leukemia cells [Exosomes]      More >>> 26100252   
Colorectal cancer cells [Exosomes]      More >>> 17956143   
Colorectal cancer cells [Microvesicles]      More >>> 19930720   
Colorectal cancer cells [Exosomes]      More >>> 22285593   
Colorectal cancer cells [Exosomes]      More >>> 23161513   
Colorectal cancer cells [Exosomes]      More >>> 23161513   
Colorectal cancer cells [Exosomes]      More >>> 23161513   
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles]      More >>> 23230278   
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles]      More >>> 23230278   
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles]      More >>> 23230278   
Colorectal cancer cells [Exosomes/Membrane vesicles]      More >>> 23585443   
Colorectal cancer cells [Exosomes/Membrane vesicles]      More >>> 23585443   
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes]      More >>> 24009881   
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes]      More >>> 24009881   
Colorectal cancer cells [Extracellular vesicles]      More >>> 27894104   
Colorectal cancer cells [Extracellular vesicles]      More >>> 27894104   
Colorectal cancer cells [Microvesicles]      More >>> 28842968   
Colorectal cancer cells [Microvesicles]      More >>> 28842968   
Colorectal cancer cells [Extracellular vesicles]      More >>> 28842968   
Colorectal cancer cells [Extracellular vesicles]      More >>> 28842968   
Dendritic cells [Microvesicles]      More >>> 26858453   
Dendritic cells [Microvesicles]      More >>> 26858453   
Dendritic cells [Exosomes]      More >>> 26858453   
Dendritic cells [Exosomes]      More >>> 26858453   
Dendritic cells [Extracellular vesicles]      More >>> 26858453   
Dendritic cells [Extracellular vesicles]      More >>> 26858453   
Duodenal cancer cells [Exosomes]      More >>> 25065644   
Duodenal cancer cells [Exosomes]      More >>> 25065644   
Endothelial cells [Microparticles]      More >>> 18563738   
Endothelial cells [Microparticles]      More >>> 18563738   
Endothelial cells [Microparticles]      More >>> 18563738   
Endothelial cells [Membrane vesicles/Extracellular vesicles]      More >>> 23436686   
Endothelial cells [Exosomes/Extracellular vesicles]      More >>> 24009886   
Epididymal fluid [Prostasomes]      More >>> 18482993   
Epithelial cells [Membrane blebs]      More >>> 19567368   
Epithelial cells [Exosomes]      More >>> 25776846   
Epithelial cells [Exosomes]      More >>> 25776846   
Glioblastoma cells [Microvesicles]      More >>> 19011622   
Glioblastoma cells [Exosomes]      More >>> 25802036   
Glioblastoma cells [Extracellular vesicles]      More >>> 27770278   
Glioblastoma cells [Extracellular vesicles]      More >>> 27770278   
Glioblastoma cells [Extracellular vesicles]      More >>> 27770278   
Glioblastoma cells [Extracellular vesicles]      More >>> 27770278   
Glioblastoma cells [Extracellular vesicles]      More >>> 27770278   
Glioblastoma cells [Microvesicles]      More >>> 29937354   
Glioblastoma cells [Microvesicles]      More >>> 29937354   
Glioblastoma cells [Exosomes]      More >>> 29937354   
Glioblastoma cells [Exosomes]      More >>> 29937354   
Glioblastoma cells [Exosomes]      More >>> 29937354   
Glioblastoma cells [Microvesicles]      More >>> 23807490   
Glioblastoma cells [Extracellular vesicles]      More >>> 27770278   
Keratinocytes [Exosomes]      More >>> 19530224   
Keratinocytes [Exosomes]      More >>> 19530224   
Kidney cancer cells [Extracellular vesicles]      More >>> 27894104   
Kidney cancer cells [Extracellular vesicles]      More >>> 27894104   
Kidney cancer cells [Extracellular vesicles]      More >>> 27894104   
Leukemia cells [Extracellular vesicles]      More >>> 27894104   
Leukemia cells [Extracellular vesicles]      More >>> 27894104   
Leukemia cells [Extracellular vesicles]      More >>> 27894104   
Lung cancer cells [Extracellular vesicles]      More >>> 27894104   
Lung cancer cells [Extracellular vesicles]      More >>> 27894104   
Lymphoblasts [Exosomes]      More >>> 19912576   
Lymphoblasts [Exosomes]      More >>> 19912576   
Macrophages [Exosomes]      More >>> 22711894   
Macrophages [Exosomes]      More >>> 22711894   
Macrophages [Exosomes]      More >>> 22711894   
Malignant pleural effusions [Exosomes]      More >>> 21601258   
Malignant pleural effusions [Exosomes/Microvesicles/Ectosomes/Microparticles]      More >>> 23585444   
Melanoma cells [Exosomes]      More >>> 22635005   
Melanoma cells [Extracellular vesicles]      More >>> 27894104   
Melanoma cells [Extracellular vesicles]      More >>> 27894104   
Melanoma cells [Extracellular vesicles]      More >>> 27894104   
Mesenchymal stem cells [Exosomes]      More >>> Unpublished / Not applicable
Mesenchymal stem cells [Microvesicles]      More >>> 22148876   
Mesenchymal stem cells [Microvesicles]      More >>> 22148876   
Mesenchymal stem cells [Microvesicles]      More >>> 22148876   
Mesothelioma cells [Exosomes]      More >>> 15111327   
Neonatal myoblast cells [Microvesicles/Nanovesicles]      More >>> 23000592   
Neonatal myoblast cells [Microvesicles/Nanovesicles]      More >>> 23000592   
Neutrophils [Microparticles]      More >>> 23660474   
Neutrophils [Microparticles]      More >>> 23660474   
Osteosarcoma cells [Matrix vesicles]      More >>> 21515422   
Ovarian cancer cells [Exosomes]      More >>> 23333927   
Ovarian cancer cells [Exosomes]      More >>> 23333927   
Ovarian cancer cells [Extracellular vesicles]      More >>> 27894104   
Ovarian cancer cells [Extracellular vesicles]      More >>> 27894104   
Ovarian cancer cells [Extracellular vesicles]      More >>> 27894104   
Ovarian cancer cells [Extracellular vesicles]      More >>> 27894104   
Ovarian cancer cells [Exosomes]      More >>> 24434149   
Ovarian cancer cells [Exosomes]      More >>> 24434149   
Ovarian cancer cells [Exosomes]      More >>> 24434149   
Ovarian cancer cells [Exosomes]      More >>> 24434149   
Placental mesenchymal stem cells [Exosomes]      More >>> 23861904   
Plasma [Microparticles]      More >>> 22329422   
Plasma [Microparticles]      More >>> 23056467   
Plasma [Exosomes]      More >>> 22046311   
Platelets [Microparticles]      More >>> 23601281   
Prostate cancer cells [Exosomes]      More >>> 22723089   
Prostate cancer cells [Exosomes]      More >>> 22030351   
Prostate cancer cells [Extracellular vesicles]      More >>> 27894104   
Prostate cancer cells [Exosomes]      More >>> 25102470   
Prostate cancer cells [Exosomes]      More >>> 25844599   
Prostate cancer cells [Exosomes]      More >>> 25844599   
Prostate cancer cells [Exosomes]      More >>> 24391718   
Prostate cancer cells [Exosomes]      More >>> 24391718   
Prostate cancer cells [Exosomes]      More >>> 24391718   
Prostate cancer cells [Exosomes]      More >>> 24371517   
Prostate cancer cells [Exosomes]      More >>> 24371517   
Prostate epithelial cells [Exosomes]      More >>> 24391718   
Prostate epithelial cells [Exosomes]      More >>> 24391718   
Prostate epithelial cells [Exosomes]      More >>> 24391718   
Prostate epithelial cells [Exosomes]      More >>> 24391718   
Prostate epithelial cells [Exosomes]      More >>> 24391718   
Prostate epithelial cells [Exosomes]      More >>> 24391718   
Red blood cells [Microvesicles/Nanovesicles]      More >>> 18346024   
Red blood cells [Microvesicles/Nanovesicles]      More >>> 18346024   
Red blood cells [Microvesicles/Nanovesicles]      More >>> 18346024   
Red blood cells [Microvesicles/Nanovesicles]      More >>> 18346024   
Red blood cells [Microvesicles/Nanovesicles]      More >>> 18346024   
Red blood cells [Microvesicles/Nanovesicles]      More >>> 18346024   
Renal proximal tubule cells [Exosomes]      More >>> 24976626   
Retinal pigment epithelial cells [Exosomes]      More >>> 24400796   
Saliva [Exosomes]      More >>> 19199708   
Saliva [Exosomes/Membrane vesicles]      More >>> 20052414   
Seminal fluid [Prostasomes]      More >>> 12746840   
Seminal fluid [Exosomes/Prostasomes]      More >>> 18819103   
Seminal plasma [Prostasomes]      More >>> 26272980   
Seminal plasma [Prostasomes]      More >>> 23707955   
Skeletal tissue [Prostasomes]      More >>> 20332430   
Squamous carcinoma cells [Exosomes]      More >>> 20124223   
Synovial fluid [Microvesicles]      More >>> 23185418   
Synovial fluid [Microvesicles]      More >>> 23185418   
Synovial fluid [Microvesicles]      More >>> 23185418   
T cells [Microparticles]      More >>> 16342139   
T cells [Microparticles]      More >>> 16342139   
T cells [Exosomes]      More >>> 28811610   
T cells [Microvesicles]      More >>> 28811610   
T cells [Apoptotic bodies]      More >>> 28811610   
T cells [Exosomes]      More >>> 23463506   
T cells [Exosomes]      More >>> 23463506   
T cells [Exosomes]      More >>> 23463506   
Tabecular meshwork cells [Exosomes]      More >>> 21362503   
Thymus [Exosomes]      More >>> 23844026   
Tracheobronchial cells [Exosomes]      More >>> 19190083   
Umblical cord mesenchymal stem cells [Microvesicles]      More >>> 29148239   
Umblical cord mesenchymal stem cells [Microvesicles]      More >>> 29148239   
Umblical cord mesenchymal stem cells [Microvesicles]      More >>> 29148239   
Umblical cord mesenchymal stem cells [Microvesicles]      More >>> 29148239   
Umblical cord mesenchymal stem cells [Microvesicles]      More >>> 29148239   
Umblical cord mesenchymal stem cells [Microvesicles]      More >>> 29148239   
Urine [Exosomes]      More >>> 17700640   
Urine [Exosomes]      More >>> 19056867   
Urine [Exosomes]      More >>> 21362503   
Urine [Exosomes/Membrane particles]      More >>> 19158352   
Urine [Exosomes/Membrane vesicles]      More >>> 22106071   
Urine [Exosomes]      More >>> 22418980   
Urine [Exosomes]      More >>> 22418980   
Urine [Exosomes/Membrane vesicles]      More >>> 23082778   
Urine [Exosomes/Membrane vesicles]      More >>> 23082778   
Urine [Exosomes/Membrane vesicles]      More >>> 23376485   
Urine [Exosomes/Nanovesicles]      More >>> 23511837   
Urine [Exosomes/Nanovesicles]      More >>> 23511837   
Urine [Exosomes/Microvesicles]      More >>> 23533145   
Urine [Exosomes/Microvesicles]      More >>> 23533145   
Urine [Exosomes]      More >>> 25471207   
Urine [Extracellular vesicles]      More >>> 29988836   
Urine [Exosomes]      More >>> 24211404   
Urine [Exosomes]      More >>> 22641613   
Urothelial cells [Extracellular vesicles]      More >>> 29207636   
Urothelial cells [Extracellular vesicles]      More >>> 29207636   
 Experiment description of studies that identified ANXA1 in extracellular vesicles
1
Experiment ID58
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Western blotting
PubMed ID 17700640   
OrganismHomo sapiens
Experiment descriptionCD24 is a marker of exosomes secreted into urine and amniotic fluid.
AuthorsKeller S, Rupp C, Stoeck A, Runz S, Fogel M, Lugert S, Hager HD, Abdel-Bakky MS, Gutwein P, Altevogt P
Journal name KI
Publication year2007
SampleAmniotic fluid
Sample nameAmniotic fluid
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density1.08-1.14 g/mL
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -
2
Experiment ID120
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Western blotting
PubMed ID 21362503   
OrganismHomo sapiens
Experiment descriptionProtein profile of exosomes from trabecular meshwork cells.
AuthorsStamer WD, Hoffman EA, Luther JM, Hachey DL, Schey KL.
Journal name JOP
Publication year2011
SampleAqueous humor
Sample nameAqueous humor - Normal
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV110011: EV-METRIC:33%, 33%, 56%
3
Experiment ID108
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Western blotting
PubMed ID 21601258   
OrganismHomo sapiens
Experiment descriptionLoss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.
AuthorsRupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P.
Journal name GO
Publication year2011
SampleAscites
Sample nameMalignant ascites - ovarian cancer
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Immunobeads (EpCAM, CD24)
Flotation density1.04-1.15 g/mL
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Immunoelectron microscopy
EV-TRACK EV110020: EV-METRIC:13%, 63%, 50%
4
Experiment ID110
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Western blotting
PubMed ID 21601258   
OrganismHomo sapiens
Experiment descriptionLoss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.
AuthorsRupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P.
Journal name GO
Publication year2011
SampleAscites
Sample nameAscites - liver cirrhosis
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density1.04-1.10 g/mL
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Immunoelectron microscopy
EV-TRACK EV110020: EV-METRIC:13%, 63%, 50%
5
Experiment ID131
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Western blotting
PubMed ID 19188015   
OrganismHomo sapiens
Experiment descriptionSystemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes
AuthorsKeller S, Kö AK, Marmé, Runz S, Wolterink S, Koensgen D, Mustea A, Sehouli J, Altevogt P.
Journal name CL
Publication year2009
SampleAscites
Sample nameMalignant ascites - Ovarian cancer
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density1.08–-1.14 g/mL
Molecules identified in the studyProtein
Lipids
Methods used in the studyCytofluorographic analysis
Annexin V-FITC
Western blotting
FACS
EV-TRACK -
6
Experiment ID157
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 21630462   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of microvesicles derived from human colorectal cancer ascites
AuthorsChoi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS
Journal name Proteomics
Publication year2011
SampleAscites
Sample nameMalignant ascites - Colorectal cancer patient 1
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
OptiPrep density gradient
Flotation density1.09 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK EV110017: EV-METRIC:38%
7
Experiment ID158
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 21630462   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of microvesicles derived from human colorectal cancer ascites
AuthorsChoi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS
Journal name Proteomics
Publication year2011
SampleAscites
Sample nameMalignant ascites - Colorectal cancer patient 2
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
OptiPrep density gradient
Flotation density1.09 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK EV110017: EV-METRIC:38%
8
Experiment ID159
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 21630462   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of microvesicles derived from human colorectal cancer ascites
AuthorsChoi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS
Journal name Proteomics
Publication year2011
SampleAscites
Sample nameMalignant ascites - Colorectal cancer patient 3
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
OptiPrep density gradient
Flotation density1.09 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK EV110017: EV-METRIC:38%
9
Experiment ID1059
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 30006486   
OrganismHomo sapiens
Experiment descriptionThe impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.
AuthorsChoi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J.
Journal name Mol Cell Proteomics.
Publication year2018
SampleAstrocytoma cells
Sample nameU373 - EVs 1
Isolation/purification methodsFiltration
Ultracentrifugation
Density gradient centrifugation
Flotation density1.09-1.13 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -
10
Experiment ID1060
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 30006486   
OrganismHomo sapiens
Experiment descriptionThe impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.
AuthorsChoi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J.
Journal name Mol Cell Proteomics.
Publication year2018
SampleAstrocytoma cells
Sample nameU373 - EVs 2
Isolation/purification methodsFiltration
Ultracentrifugation
Density gradient centrifugation
Flotation density1.09-1.13 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
11
Experiment ID1061
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 30006486   
OrganismHomo sapiens
Experiment descriptionThe impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.
AuthorsChoi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J.
Journal name Mol Cell Proteomics.
Publication year2018
SampleAstrocytoma cells
Sample nameU373 - EVs 3
Isolation/purification methodsFiltration
Ultracentrifugation
Density gradient centrifugation
Flotation density1.09-1.13 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
12
Experiment ID1062
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 30006486   
OrganismHomo sapiens
Experiment descriptionThe impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.
AuthorsChoi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J.
Journal name Mol Cell Proteomics.
Publication year2018
SampleAstrocytoma cells
Sample nameU373vIII - EVs 1
Isolation/purification methodsFiltration
Ultracentrifugation
Density gradient centrifugation
Flotation density1.09-1.13 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -
13
Experiment ID1063
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 30006486   
OrganismHomo sapiens
Experiment descriptionThe impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.
AuthorsChoi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J.
Journal name Mol Cell Proteomics.
Publication year2018
SampleAstrocytoma cells
Sample nameU373vIII - EVs 2
Isolation/purification methodsFiltration
Ultracentrifugation
Density gradient centrifugation
Flotation density1.09-1.13 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
14
Experiment ID1064
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 30006486   
OrganismHomo sapiens
Experiment descriptionThe impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.
AuthorsChoi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J.
Journal name Mol Cell Proteomics.
Publication year2018
SampleAstrocytoma cells
Sample nameU373vIII - EVs 3
Isolation/purification methodsFiltration
Ultracentrifugation
Density gradient centrifugation
Flotation density1.09-1.13 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
15
Experiment ID395
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 19413345   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis.
AuthorsMiguet L, Béchade G, Fornecker L, Zink E, Felden C, Gervais C, Herbrecht R, Van Dorsselaer A, Mauvieux L, Sanglier-Cianferani S.
Journal name J Proteome Res
Publication year2009
SampleB cells
Sample namePatients of chronic lymphocytic leukemia-B cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
16
Experiment ID396
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 19413345   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis.
AuthorsMiguet L, Béchade G, Fornecker L, Zink E, Felden C, Gervais C, Herbrecht R, Van Dorsselaer A, Mauvieux L, Sanglier-Cianferani S.
Journal name J Proteome Res
Publication year2009
SampleB cells
Sample namePatients of mantle cell lymphoma-B cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
17
Experiment ID397
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 19413345   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis.
AuthorsMiguet L, Béchade G, Fornecker L, Zink E, Felden C, Gervais C, Herbrecht R, Van Dorsselaer A, Mauvieux L, Sanglier-Cianferani S.
Journal name J Proteome Res
Publication year2009
SampleB cells
Sample namePatients of small cell lymphoma-B cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
18
Experiment ID76
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 20224111   
OrganismHomo sapiens
Experiment descriptionProteomics analysis of bladder cancer exosomes.
AuthorsWelton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A.
Journal name MCP
Publication year2010
SampleBladder cancer cells
Sample nameHT1376
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density1.10-1.19 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
EV-TRACK EV100014: EV-METRIC:38%, 14%, 44%
19
Experiment ID905
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29207636   
OrganismHomo sapiens
Experiment descriptionCharacterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer
AuthorsSilvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF.
Journal name Oncotarget
Publication year2017
SampleBladder cancer cells
Sample nameTCCSUP
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
20
Experiment ID930
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29207636   
OrganismHomo sapiens
Experiment descriptionCharacterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.
AuthorsSilvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF.
Journal name Oncotarget
Publication year2017
SampleBladder cancer cells
Sample nameTCCSUP
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
21
Experiment ID654
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 28290293   
OrganismBos taurus
Experiment descriptionComparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.
AuthorsYng M, Song D, Cao X, Wu R, Liu B, Ye W, Wu J, Yue X.
Journal name Food Res Int
Publication year2017
SampleBovine milk
Sample nameColostrum
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Flotation density1.7 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
22
Experiment ID655
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 28290293   
OrganismBos taurus
Experiment descriptionComparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.
AuthorsYng M, Song D, Cao X, Wu R, Liu B, Ye W, Wu J, Yue X.
Journal name Food Res Int
Publication year2017
SampleBovine milk
Sample nameMature milk
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Flotation density1.7 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
23
Experiment ID584
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleBrain cancer cells
Sample nameSNB-19
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
24
Experiment ID585
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleBrain cancer cells
Sample nameSNB-75
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
25
Experiment ID575
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleBreast cancer cells
Sample nameBT549
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
26
Experiment ID577
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleBreast cancer cells
Sample nameMCF7
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
27
Experiment ID1018
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 22399603   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of exosome-like vesicles derived from breast cancer cells.
AuthorsPalazzolo G, Albanese NN, DI Cara G, Gygax D, Vittorelli ML, Pucci-Minafra I.
Journal name Anticancer Res
Publication year2012
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV120036: EV-METRIC:44%
28
Experiment ID1254
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 24468161   
OrganismHomo sapiens
Experiment descriptionMolecular characterization of exosome-like vesicles from breast cancer cells.
AuthorsKruger S, Abd Elmageed ZY, Hawke DH, Wör PM, Jansen DA, Abdel-Mageed AB, Alt EU, Izadpanah R.
Journal name BMC Cancer.
Publication year2014
SampleBreast cancer cells
Sample nameMCF7
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Microarray
RT-PCR
Western blotting
EV-TRACK EV140357: EV-METRIC:22%
29
Experiment ID574
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ-Orbitrap Elite, Q-Exactive]
PubMed ID 27601599   
OrganismHomo sapiens
Experiment descriptionComprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components
AuthorsVan Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH
Journal name MCP
Publication year2016
SampleBreast milk
Sample nameBreast milk - normal
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.12-1.18 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV160000: EV-METRIC:50%
30
Experiment ID652
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 28290293   
OrganismHomo sapiens
Experiment descriptionComparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.
AuthorsYng M, Song D, Cao X, Wu R, Liu B, Ye W, Wu J, Yue X.
Journal name Food Res Int
Publication year2017
SampleBreast milk
Sample nameColostrum
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Flotation density1.7 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
31
Experiment ID653
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 28290293   
OrganismHomo sapiens
Experiment descriptionComparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.
AuthorsYng M, Song D, Cao X, Wu R, Liu B, Ye W, Wu J, Yue X.
Journal name Food Res Int
Publication year2017
SampleBreast milk
Sample nameMature milk
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Flotation density1.7 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
32
Experiment ID950
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27601599   
OrganismHomo sapiens
Experiment descriptionComprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.
Authorsvan Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH
Journal name Mol Cell Proteomics
Publication year2016
SampleBreast milk
Sample nameMilk - derived EVs - D1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.12-1.18 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV160000: EV-METRIC:50%
33
Experiment ID951
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27601599   
OrganismHomo sapiens
Experiment descriptionComprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.
Authorsvan Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH
Journal name Mol Cell Proteomics
Publication year2016
SampleBreast milk
Sample nameMilk - derived EVs - D2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.12-1.18 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV160000: EV-METRIC:50%
34
Experiment ID952
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27601599   
OrganismHomo sapiens
Experiment descriptionComprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.
Authorsvan Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH
Journal name Mol Cell Proteomics
Publication year2016
SampleBreast milk
Sample nameMilk - derived EVs - D3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.12-1.18 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV160000: EV-METRIC:50%
35
Experiment ID954
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27601599   
OrganismHomo sapiens
Experiment descriptionComprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.
Authorsvan Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH
Journal name Mol Cell Proteomics
Publication year2016
SampleBreast milk
Sample nameMilk - derived EVs - D5
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.12-1.18 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV160000: EV-METRIC:50%
36
Experiment ID956
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27601599   
OrganismHomo sapiens
Experiment descriptionComprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.
Authorsvan Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH
Journal name Mol Cell Proteomics
Publication year2016
SampleBreast milk
Sample nameMilk - derived EVs - D7
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.12-1.18 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV160000: EV-METRIC:50%
37
Experiment ID957
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27601599   
OrganismHomo sapiens
Experiment descriptionComprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.
Authorsvan Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH
Journal name Mol Cell Proteomics
Publication year2016
SampleBreast milk
Sample nameMilk - derived EVs - pooled
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.12-1.18 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV160000: EV-METRIC:50%
38
Experiment ID1207
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29127410   
OrganismHomo sapiens
Experiment descriptionUltrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.
AuthorsBenedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM.
Journal name Sci Rep.
Publication year2017
SampleBronchial epithelial cells
Sample nameUltrafiltration and size exclusion chromatography sample 1
Isolation/purification methodsUltrafiltration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
39
Experiment ID1208
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29127410   
OrganismHomo sapiens
Experiment descriptionUltrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.
AuthorsBenedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM.
Journal name Sci Rep.
Publication year2017
SampleBronchial epithelial cells
Sample nameUltrafiltration and size exclusion chromatography sample 2
Isolation/purification methodsUltrafiltration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
40
Experiment ID1209
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29127410   
OrganismHomo sapiens
Experiment descriptionUltrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.
AuthorsBenedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM.
Journal name Sci Rep.
Publication year2017
SampleBronchial epithelial cells
Sample nameUltrafiltration and size exclusion chromatography sample 3
Isolation/purification methodsUltrafiltration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
41
Experiment ID1210
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29127410   
OrganismHomo sapiens
Experiment descriptionUltrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.
AuthorsBenedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM.
Journal name Sci Rep.
Publication year2017
SampleBronchial epithelial cells
Sample nameUltrafiltration and size exclusion chromatography sample 4
Isolation/purification methodsUltrafiltration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
42
Experiment ID1211
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29127410   
OrganismHomo sapiens
Experiment descriptionUltrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.
AuthorsBenedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM.
Journal name Sci Rep.
Publication year2017
SampleBronchial epithelial cells
Sample nameUltrafiltration and size exclusion chromatography sample 5
Isolation/purification methodsUltrafiltration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
43
Experiment ID1212
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29127410   
OrganismHomo sapiens
Experiment descriptionUltrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.
AuthorsBenedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM.
Journal name Sci Rep.
Publication year2017
SampleBronchial epithelial cells
Sample nameUltracentrifugation, sample 1
Isolation/purification methodsUltracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
44
Experiment ID1213
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29127410   
OrganismHomo sapiens
Experiment descriptionUltrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.
AuthorsBenedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM.
Journal name Sci Rep.
Publication year2017
SampleBronchial epithelial cells
Sample nameUltracentrifugation, sample 2
Isolation/purification methodsUltracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
45
Experiment ID1214
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29127410   
OrganismHomo sapiens
Experiment descriptionUltrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.
AuthorsBenedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM.
Journal name Sci Rep.
Publication year2017
SampleBronchial epithelial cells
Sample nameUltracentrifugation, sample 3
Isolation/purification methodsUltracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
46
Experiment ID408
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Proton Nucelar Magnetic Resonance Spectrometry
PubMed ID 20031610   
OrganismHomo sapiens
Experiment descriptionProteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.
AuthorsMayr M, Grainger D, Mayr U, Leroyer AS, Leseche G, Sidibe A, Herbin O, Yin X, Gomes A, Madhu B, Griffiths JR, Xu Q, Tedgui A, Boulanger CM.
Journal name Circ Cardiovasc Genet
Publication year2009
SampleCarotid atherosclerotic plaques
Sample nameNormal-Carotid atherosclerotic plaque
Isolation/purification methods-
Flotation density-
Molecules identified in the studyMetabolites
Methods used in the studyProton Nucelar Magnetic Resonance Spectrometry
EV-TRACK -
47
Experiment ID409
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 20031610   
OrganismHomo sapiens
Experiment descriptionProteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.
AuthorsMayr M, Grainger D, Mayr U, Leroyer AS, Leseche G, Sidibe A, Herbin O, Yin X, Gomes A, Madhu B, Griffiths JR, Xu Q, Tedgui A, Boulanger CM.
Journal name Circ Cardiovasc Genet
Publication year2009
SampleCarotid atherosclerotic plaques
Sample namePatients of carotid atherosclerosis-Carotid atherosclerotic plaque
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
48
Experiment ID721
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 26148937   
OrganismHomo sapiens
Experiment descriptionProteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.
AuthorsDutta S, Reamtong O, Panvongsa W, Kitdumrongthum S, Janpipatkul K, Sangvanich P, Piyachaturawat P, Chairoungdua A.
Journal name Biochim Biophys Acta
Publication year2015
SampleCholangiocarcinoma cells
Sample nameKKU-M213
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150040: EV-METRIC:11%
49
Experiment ID899
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 26100252   
OrganismHomo sapiens
Experiment descriptionExosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts
AuthorsPaggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E.
Journal name Blood
Publication year2015
SampleChronic lymphocytic leukemia cells
Sample nameCLL cells - Rep 1
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Flotation density1.15-1.17 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150015: EV-METRIC:22%, 44%
50
Experiment ID900
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 26100252   
OrganismHomo sapiens
Experiment descriptionExosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts
AuthorsPaggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E.
Journal name Blood
Publication year2015
SampleChronic lymphocytic leukemia cells
Sample nameCLL cells - Rep 2
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Flotation density1.15-1.17 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150015: EV-METRIC:22%, 44%
51
Experiment ID901
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 26100252   
OrganismHomo sapiens
Experiment descriptionExosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts
AuthorsPaggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E.
Journal name Blood
Publication year2015
SampleChronic lymphocytic leukemia cells
Sample nameJVM-3
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Flotation density1.15-1.17 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150015: EV-METRIC:22%, 44%
52
Experiment ID20
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 17956143   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of microvesicles derived from human colorectal cancer cells.
AuthorsChoi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS
Journal name JPR
Publication year2007
SampleColorectal cancer cells
Sample nameHT29
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Diafiltration
Flotation density1.16 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
Western blotting
EV-TRACK -
53
Experiment ID303
Identified moleculemrna
Extracellular vesicle typeMicrovesicles
Identification method Microarray [Illumina]
PubMed ID 19930720   
OrganismHomo sapiens
Experiment descriptionColorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells
AuthorsHong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS
Journal name BMC Genomics
Publication year2009
SampleColorectal cancer cells
Sample nameSW480
Isolation/purification methodsDifferential centrifugation
Ultrafiltration
OptiPrep density gradient
Flotation density1.09 g/mL
Molecules identified in the studyProtein
mRNA
Methods used in the studyWestern blotting
RT-PCR
Microarray [Illumina]
EV-TRACK -
54
Experiment ID349
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry [Orbitrap]
PubMed ID 22285593   
OrganismHomo sapiens
Experiment descriptionComparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.
AuthorsTauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ
Journal name Methods
Publication year2012
SampleColorectal cancer cells
Sample nameLIM1863 - OptiPrep density gradient
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [Orbitrap]
Western blotting
EV-TRACK EV120024: EV-METRIC:25%, 33%, 50%
55
Experiment ID480
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 23161513   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
AuthorsDemory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name Mol Cell Proteomics
Publication year2012
SampleColorectal cancer cells
Sample nameDKO-1
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130004: EV-METRIC:44%
56
Experiment ID481
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 23161513   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
AuthorsDemory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name Mol Cell Proteomics
Publication year2012
SampleColorectal cancer cells
Sample nameDks-8
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130004: EV-METRIC:44%
57
Experiment ID482
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 23161513   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
AuthorsDemory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ.
Journal name Mol Cell Proteomics
Publication year2012
SampleColorectal cancer cells
Sample nameDLD-1
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130004: EV-METRIC:44%
58
Experiment ID486
Identified moleculeprotein
Extracellular vesicle typeExosomes/Extracellular vesicles/Microvesicles
Identification method Mass spectrometry
PubMed ID 23230278   
OrganismHomo sapiens
Experiment descriptionTwo distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.
AuthorsTauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ.
Journal name Mol Cell Proteomics
Publication year2012
SampleColorectal cancer cells
Sample nameA33 affinity purified exosomes-Colorectal cancer cells (LIM1863)
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130020: EV-METRIC:38%
59
Experiment ID487
Identified moleculeprotein
Extracellular vesicle typeExosomes/Extracellular vesicles/Microvesicles
Identification method Mass spectrometry
PubMed ID 23230278   
OrganismHomo sapiens
Experiment descriptionTwo distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.
AuthorsTauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ.
Journal name Mol Cell Proteomics
Publication year2012
SampleColorectal cancer cells
Sample nameEpCAM affinity purified exosomes-Colorectal cancer cells (LIM1863)
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130020: EV-METRIC:38%
60
Experiment ID488
Identified moleculeprotein
Extracellular vesicle typeExosomes/Extracellular vesicles/Microvesicles
Identification method Mass spectrometry
PubMed ID 23230278   
OrganismHomo sapiens
Experiment descriptionTwo distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.
AuthorsTauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ.
Journal name Mol Cell Proteomics
Publication year2012
SampleColorectal cancer cells
Sample nameShed vesicles-Colorectal cancer cells (LIM1863)
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130020: EV-METRIC:38%
61
Experiment ID517
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
Identification method Mass spectrometry
PubMed ID 23585443   
OrganismHomo sapiens
Experiment descriptionProteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components.
AuthorsJi H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ.
Journal name Proteomics
Publication year2013
SampleColorectal cancer cells
Sample nameSW480
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130010: EV-METRIC:44%
62
Experiment ID518
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
Identification method Mass spectrometry
PubMed ID 23585443   
OrganismHomo sapiens
Experiment descriptionProteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components.
AuthorsJi H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ.
Journal name Proteomics
Publication year2013
SampleColorectal cancer cells
Sample nameSW620
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130010: EV-METRIC:44%
63
Experiment ID549
Identified moleculeprotein
Extracellular vesicle typeExosomes/Extracellular vesicles/Microvesicles/Ectosomes
Identification method Mass spectrometry
PubMed ID 24009881   
OrganismHomo sapiens
Experiment descriptionQuantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.
AuthorsChoi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS.
Journal name J Extracell Vesicles
Publication year2012
SampleColorectal cancer cells
Sample nameSW480
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120013: EV-METRIC:50%
64
Experiment ID550
Identified moleculeprotein
Extracellular vesicle typeExosomes/Extracellular vesicles/Microvesicles/Ectosomes
Identification method Mass spectrometry
PubMed ID 24009881   
OrganismHomo sapiens
Experiment descriptionQuantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.
AuthorsChoi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS.
Journal name J Extracell Vesicles
Publication year2012
SampleColorectal cancer cells
Sample nameSW620
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120013: EV-METRIC:50%
65
Experiment ID587
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleColorectal cancer cells
Sample nameColo205
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
66
Experiment ID588
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleColorectal cancer cells
Sample nameHCC 2998
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
67
Experiment ID696
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 28842968   
OrganismHomo sapiens
Experiment descriptionInsulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.
AuthorsLiem M, Ang CS, Mathivanan S.
Journal name Proteomics
Publication year2017
SampleColorectal cancer cells
Sample nameLIM1215- insulin induced
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170021: EV-METRIC:44%, 44%
68
Experiment ID697
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 28842968   
OrganismHomo sapiens
Experiment descriptionInsulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.
AuthorsLiem M, Ang CS, Mathivanan S.
Journal name Proteomics
Publication year2017
SampleColorectal cancer cells
Sample nameLIM1215- non-induced
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170021: EV-METRIC:44%, 44%
69
Experiment ID1049
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 28842968   
OrganismHomo sapiens
Experiment descriptionInsulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.
AuthorsLiem M, Ang CS, Mathivanan S.
Journal name Proteomics.
Publication year2017
SampleColorectal cancer cells
Sample name LIM1215 - NI
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV170021: EV-METRIC:44%, 44%
70
Experiment ID1050
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 28842968   
OrganismHomo sapiens
Experiment descriptionInsulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.
AuthorsLiem M, Ang CS, Mathivanan S.
Journal name Proteomics.
Publication year2017
SampleColorectal cancer cells
Sample namelim1215 - II
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV170021: EV-METRIC:44%, 44%
71
Experiment ID562
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 26858453   
OrganismHomo sapiens
Experiment descriptionProteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
AuthorsKowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C
Journal name PNAS
Publication year2016
SampleDendritic cells
Sample namemonocyte-derived dendritic cells (F3 10K)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density1.11 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
72
Experiment ID563
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 26858453   
OrganismHomo sapiens
Experiment descriptionProteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
AuthorsKowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C
Journal name PNAS
Publication year2016
SampleDendritic cells
Sample namemonocyte-derived dendritic cells (F5 10K)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density1.14 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
73
Experiment ID564
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry [LTQ]
PubMed ID 26858453   
OrganismHomo sapiens
Experiment descriptionProteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
AuthorsKowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C
Journal name PNAS
Publication year2016
SampleDendritic cells
Sample namemonocyte-derived dendritic cells (F3 100K)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density1.11 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
74
Experiment ID565
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry [LTQ ORBITRAP]
PubMed ID 26858453   
OrganismHomo sapiens
Experiment descriptionProteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
AuthorsKowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C
Journal name PNAS
Publication year2016
SampleDendritic cells
Sample namemonocyte-derived dendritic cells (F5 100K)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density1.14 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ ORBITRAP]
EV-TRACK -
75
Experiment ID566
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ FUSION]
PubMed ID 26858453   
OrganismHomo sapiens
Experiment descriptionProteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
AuthorsKowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C
Journal name PNAS
Publication year2016
SampleDendritic cells
Sample namemonocyte-derived dendritic cells (Igg1 PD)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Immunobeads (Igg1 PD)
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ FUSION]
EV-TRACK -
76
Experiment ID567
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ FUSION]
PubMed ID 26858453   
OrganismHomo sapiens
Experiment descriptionProteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
AuthorsKowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C
Journal name PNAS
Publication year2016
SampleDendritic cells
Sample namemonocyte-derived dendritic cells (Igg1 FT)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Immunobeads (Igg1 FT)
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ FUSION]
EV-TRACK -
77
Experiment ID1086
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 25065644   
OrganismHomo sapiens
Experiment descriptionExosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.
AuthorsOhshima K, Kanto K, Hatakeyama K, Ide T, Wakabayashi-Nakao K, Watanabe Y, Sakura N, Terashima M, Yamaguchi K, Mochizuki T.
Journal name Proteomics
Publication year2014
SampleDuodenal cancer cells
Sample nameAZ-P7a (metastatic)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultrafiltration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140088: EV-METRIC:44%
78
Experiment ID1087
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 25065644   
OrganismHomo sapiens
Experiment descriptionExosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.
AuthorsOhshima K, Kanto K, Hatakeyama K, Ide T, Wakabayashi-Nakao K, Watanabe Y, Sakura N, Terashima M, Yamaguchi K, Mochizuki T.
Journal name Proteomics
Publication year2014
SampleDuodenal cancer cells
Sample nameAZ521 (primary)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultrafiltration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140088: EV-METRIC:44%
79
Experiment ID385
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 18563738   
OrganismHomo sapiens
Experiment descriptionComparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.
AuthorsPeterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS.
Journal name Proteomics
Publication year2008
SampleEndothelial cells
Sample nameEndothelial cells (HUVEC)
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
80
Experiment ID386
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 18563738   
OrganismHomo sapiens
Experiment descriptionComparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.
AuthorsPeterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS.
Journal name Proteomics
Publication year2008
SampleEndothelial cells
Sample nameTreated by PAI-1-Endothelial cell (HUVEC)
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
81
Experiment ID387
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 18563738   
OrganismHomo sapiens
Experiment descriptionComparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.
AuthorsPeterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS.
Journal name Proteomics
Publication year2008
SampleEndothelial cells
Sample nameTreated by TNF-alpha-Endothelial cells (HUVEC)
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
82
Experiment ID502
Identified moleculeprotein
Extracellular vesicle typeMembrane vesicles/Extracellular vesicles
Identification method Mass spectrometry
PubMed ID 23436686   
OrganismHomo sapiens
Experiment descriptionA comprehensive characterization of membrane vesicles released by autophagic human endothelial cells.
AuthorsPallet N, Sirois I, Bell C, Hanafi LA, Hamelin K, Dieudé M, Rondeau C, Thibault P, Desjardins M, Hebert MJ.
Journal name Proteomics
Publication year2013
SampleEndothelial cells
Sample nameSerum-starved-Human umbilical vascular endothelial cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130048: EV-METRIC:44%
83
Experiment ID551
Identified moleculeprotein
Extracellular vesicle typeExosomes/Extracellular vesicles
Identification method Mass spectrometry
PubMed ID 24009886   
OrganismHomo sapiens
Experiment descriptionCellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes.
Authorsde Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW.
Journal name J Extracell Vesicles
Publication year2012
SampleEndothelial cells
Sample nameStressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1)
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120004: EV-METRIC:67%
84
Experiment ID384
Identified moleculeprotein
Extracellular vesicle typeProstasomes
Identification method Mass spectrometry
PubMed ID 18482993   
OrganismHomo sapiens
Experiment descriptionProtein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach.
AuthorsThimon V, Frenette G, Saez F, Thabet M, Sullivan R.
Journal name Hum Reprod
Publication year2008
SampleEpididymal fluid
Sample nameNormal-Epididymal fluid
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
85
Experiment ID177
Identified moleculeprotein
Extracellular vesicle typeMembrane blebs
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID 19567368   
OrganismHomo sapiens
Experiment descriptionProteomics characterization of cell membrane blebs in human retinal pigment epithelium cells
AuthorsAlcazar O, Hawkridge AM, Collier TS, Cousins SW, Bhattacharya SK, Muddiman DC, Marin-Castano ME
Journal name Mol Cell Proteomics
Publication year2009
SampleEpithelial cells
Sample nameARPE-19 (Retinal epithelial cells)
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry [LTQ-FT Ultra]
EV-TRACK -
86
Experiment ID861
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 25776846   
OrganismHomo sapiens
Experiment descriptionHuman thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens
AuthorsSkogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, Ekwall O.
Journal name Immunol Cell Biol
Publication year2015
SampleEpithelial cells
Sample nameThymic tissue - culture 1
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150045: EV-METRIC:25%
87
Experiment ID862
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 25776846   
OrganismHomo sapiens
Experiment descriptionHuman thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens
AuthorsSkogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, Ekwall O.
Journal name Immunol Cell Biol
Publication year2015
SampleEpithelial cells
Sample nameThymic tissue - culture 2
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150045: EV-METRIC:25%
88
Experiment ID203
Identified moleculemrna
Extracellular vesicle typeMicrovesicles
Identification method Microarray
PubMed ID 19011622   
OrganismHomo sapiens
Experiment descriptionGlioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
AuthorsSkog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO
Journal name Nat Cell Biol
Publication year2008
SampleGlioblastoma cells
Sample nameGlioblastoma cells
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Flotation density-
Molecules identified in the studyProtein
miRNA
mRNA
Methods used in the studyRT-PCR
Antibody array
Microarray
EV-TRACK -
89
Experiment ID722
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 25802036   
OrganismHomo sapiens
Experiment descriptionGlioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.
Authorsde Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML.
Journal name Int J Cancer
Publication year2015
SampleGlioblastoma cells
Sample name U87.MG/EGFRvIII
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150064: EV-METRIC:0%, 0%, 29%
90
Experiment ID1039
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27770278   
OrganismHomo sapiens
Experiment descriptionComprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.
AuthorsMallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL.
Journal name J Neurooncol
Publication year2017
SampleGlioblastoma cells
Sample nameA172
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Flotation density1.09.1.11 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
91
Experiment ID1040
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27770278   
OrganismHomo sapiens
Experiment descriptionComprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.
AuthorsMallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL.
Journal name J Neurooncol
Publication year2017
SampleGlioblastoma cells
Sample nameLN229
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Flotation density1.09.1.11 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -
92
Experiment ID1042
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27770278   
OrganismHomo sapiens
Experiment descriptionComprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.
AuthorsMallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL.
Journal name J Neurooncol
Publication year2017
SampleGlioblastoma cells
Sample nameU251
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Flotation density1.09.1.11 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
93
Experiment ID1043
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27770278   
OrganismHomo sapiens
Experiment descriptionComprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.
AuthorsMallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL.
Journal name J Neurooncol
Publication year2017
SampleGlioblastoma cells
Sample nameT98G
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Flotation density1.09.1.11 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
94
Experiment ID1044
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27770278   
OrganismHomo sapiens
Experiment descriptionComprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.
AuthorsMallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL.
Journal name J Neurooncol
Publication year2017
SampleGlioblastoma cells
Sample nameCCF-STTG1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Flotation density1.09.1.11 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
95
Experiment ID1067
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29937354   
OrganismHomo sapiens
Experiment descriptionApoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.
AuthorsPavlyukov MS, Yu H, Bastola S, Minata M, Shender VO, Lee Y, Zhang S, Wang J, Komarova S, Wang J, Yamaguchi S, Alsheikh HA, Shi J, Chen D, Mohyeldin A, Kim SH, Shin YJ, Anufrieva K, Evtushenko EG, Antipova NV, Arapidi GP, Govorun V, Pestov NB, Shakhparonov MI, Lee LJ, Nam DH, Nakano I.
Journal name Cancer Cell
Publication year2018
SampleGlioblastoma cells
Sample nameUntreated GBM157 - MVs
Isolation/purification methodsDifferential centrifugation
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -
96
Experiment ID1068
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29937354   
OrganismHomo sapiens
Experiment descriptionApoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.
AuthorsPavlyukov MS, Yu H, Bastola S, Minata M, Shender VO, Lee Y, Zhang S, Wang J, Komarova S, Wang J, Yamaguchi S, Alsheikh HA, Shi J, Chen D, Mohyeldin A, Kim SH, Shin YJ, Anufrieva K, Evtushenko EG, Antipova NV, Arapidi GP, Govorun V, Pestov NB, Shakhparonov MI, Lee LJ, Nam DH, Nakano I.
Journal name Cancer Cell
Publication year2018
SampleGlioblastoma cells
Sample nameLethally irradiated GBM157 -MVs (apoMVs)
Isolation/purification methodsDifferential centrifugation
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -
97
Experiment ID1070
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 29937354   
OrganismHomo sapiens
Experiment descriptionApoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.
AuthorsPavlyukov MS, Yu H, Bastola S, Minata M, Shender VO, Lee Y, Zhang S, Wang J, Komarova S, Wang J, Yamaguchi S, Alsheikh HA, Shi J, Chen D, Mohyeldin A, Kim SH, Shin YJ, Anufrieva K, Evtushenko EG, Antipova NV, Arapidi GP, Govorun V, Pestov NB, Shakhparonov MI, Lee LJ, Nam DH, Nakano I.
Journal name Cancer Cell
Publication year2018
SampleGlioblastoma cells
Sample nameUntreated GBM157 - Exo - Biorep2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
98
Experiment ID1071
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 29937354   
OrganismHomo sapiens
Experiment descriptionApoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.
AuthorsPavlyukov MS, Yu H, Bastola S, Minata M, Shender VO, Lee Y, Zhang S, Wang J, Komarova S, Wang J, Yamaguchi S, Alsheikh HA, Shi J, Chen D, Mohyeldin A, Kim SH, Shin YJ, Anufrieva K, Evtushenko EG, Antipova NV, Arapidi GP, Govorun V, Pestov NB, Shakhparonov MI, Lee LJ, Nam DH, Nakano I.
Journal name Cancer Cell
Publication year2018
SampleGlioblastoma cells
Sample nameLethally irradiated GBM157 - apoExo - biorep1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -
99
Experiment ID1072
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 29937354   
OrganismHomo sapiens
Experiment descriptionApoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.
AuthorsPavlyukov MS, Yu H, Bastola S, Minata M, Shender VO, Lee Y, Zhang S, Wang J, Komarova S, Wang J, Yamaguchi S, Alsheikh HA, Shi J, Chen D, Mohyeldin A, Kim SH, Shin YJ, Anufrieva K, Evtushenko EG, Antipova NV, Arapidi GP, Govorun V, Pestov NB, Shakhparonov MI, Lee LJ, Nam DH, Nakano I.
Journal name Cancer Cell
Publication year2018
SampleGlioblastoma cells
Sample nameLethally irradiated GBM157 - apoExo - biorep2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
100
Experiment ID1274
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 23807490   
OrganismHomo sapiens
Experiment descriptionGlioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells.
AuthorsLi CC, Eaton SA, Young PE, Lee M, Shuttleworth R, Humphreys DT, Grau GE, Combes V, Bebawy M, Gong J, Brammah S, Buckland ME, Suter CM.
Journal name RNA Biol.
Publication year2013
SampleGlioblastoma cells
Sample nameU251 cells
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Microarray
EV-TRACK EV130098: EV-METRIC:29%
101
Experiment ID1041
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
Western blotting
PubMed ID 27770278   
OrganismHomo sapiens
Experiment descriptionComprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.
AuthorsMallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL.
Journal name J Neurooncol
Publication year2017
SampleGlioblastoma cells
Sample name U87MG
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Flotation density1.09.1.11 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -
102
Experiment ID398
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 19530224   
OrganismHomo sapiens
Experiment descriptionProfile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
AuthorsChavez-Muñoz C, Kilani RT, Ghahary A.
Journal name J Cell Physiol
Publication year2009
SampleKeratinocytes
Sample nameDifferentiated-Keratinocytes
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
103
Experiment ID399
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 19530224   
OrganismHomo sapiens
Experiment descriptionProfile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
AuthorsChavez-Muñoz C, Kilani RT, Ghahary A.
Journal name J Cell Physiol
Publication year2009
SampleKeratinocytes
Sample nameUndifferentiated-Keratinocytes
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
104
Experiment ID599
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleKidney cancer cells
Sample nameSN12C
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
105
Experiment ID600
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleKidney cancer cells
Sample nameTK-10
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
106
Experiment ID601
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleKidney cancer cells
Sample nameUO-31
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
107
Experiment ID602
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleLeukemia cells
Sample nameCCRF-CEM
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
108
Experiment ID604
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleLeukemia cells
Sample nameK562
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
109
Experiment ID606
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleLeukemia cells
Sample nameRPMI-8226
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
110
Experiment ID614
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleLung cancer cells
Sample nameNCI-H322M
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
111
Experiment ID615
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleLung cancer cells
Sample nameNCI-H460
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
112
Experiment ID1290
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 19912576   
OrganismHomo sapiens
Experiment descriptionHIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.
AuthorsLenassi M, Cagney G, Liao M, Vaupotic T, Bartholomeeusen K, Cheng Y, Krogan NJ, Plemenitas A, Peterlin BM.
Journal name Traffic.
Publication year2010
SampleLymphoblasts
Sample nameJurkat cells with Nef-GFP
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV100021: EV-METRIC:33%, 25%
113
Experiment ID1291
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 19912576   
OrganismHomo sapiens
Experiment descriptionHIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.
AuthorsLenassi M, Cagney G, Liao M, Vaupotic T, Bartholomeeusen K, Cheng Y, Krogan NJ, Plemenitas A, Peterlin BM.
Journal name Traffic.
Publication year2010
SampleLymphoblasts
Sample name SupT1 cells with Nef-GFP
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV100021: EV-METRIC:33%, 25%
114
Experiment ID1013
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 22711894   
OrganismHomo sapiens
Experiment descriptionBiochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.
AuthorsKadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE.
Journal name J Immunol.
Publication year2012
SampleMacrophages
Sample nameMonocyte-derived macrophages - HLA-DR pulldwon microvesicles
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyMass spectrometry
EV-TRACK EV120137: EV-METRIC:17%, 0%
115
Experiment ID1016
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 22711894   
OrganismHomo sapiens
Experiment descriptionBiochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.
AuthorsKadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE.
Journal name J Immunol.
Publication year2012
SampleMacrophages
Sample nameMonocyte-derived macrophages - Rab 11
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyMass spectrometry
EV-TRACK EV120137: EV-METRIC:17%, 0%
116
Experiment ID1017
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 22711894   
OrganismHomo sapiens
Experiment descriptionBiochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.
AuthorsKadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE.
Journal name J Immunol.
Publication year2012
SampleMacrophages
Sample nameMonocyte-derived macrophages - Vinculin/Talin pulldown exosomes
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyMass spectrometry
EV-TRACK EV120137: EV-METRIC:17%, 0%
117
Experiment ID109
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Western blotting
PubMed ID 21601258   
OrganismHomo sapiens
Experiment descriptionLoss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.
AuthorsRupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P.
Journal name GO
Publication year2011
SampleMalignant pleural effusions
Sample namePleural effusions - breast cancer
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Immunobeads (EpCAM)
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
EV-TRACK EV110020: EV-METRIC:13%, 63%, 50%
118
Experiment ID519
Identified moleculeprotein
Extracellular vesicle typeExosomes/Microvesicles/Ectosomes/Microparticles
Identification method Mass spectrometry
PubMed ID 23585444   
OrganismHomo sapiens
Experiment descriptionIdentification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions.
AuthorsPark JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, Kim KP.
Journal name Proteomics
Publication year2013
SampleMalignant pleural effusions
Sample nameNon-small cell lung cancer patient-Lung cancer pleural effusion
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130049: EV-METRIC:38%
119
Experiment ID453
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 22635005   
OrganismHomo sapiens
Experiment descriptionMelanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
AuthorsPeinado H, Alecković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D.
Journal name Nat Med
Publication year2012
SampleMelanoma cells
Sample nameB16-F10, SK-MEL-202, SK-MEL035, SK-MEL-265
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120019: EV-METRIC:44%, 44%, 44%
120
Experiment ID617
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleMelanoma cells
Sample nameLOX IMVI
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
121
Experiment ID619
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleMelanoma cells
Sample nameMALME-3M
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
122
Experiment ID625
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleMelanoma cells
Sample nameUACC-62
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
123
Experiment ID126
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
OrganismHomo sapiens
Experiment descriptionMesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
AuthorsRuenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year2011
SampleMesenchymal stem cells
Sample namehuES9.E1
Isolation/purification methodsHPLC
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Antibody array
Mass spectrometry
EV-TRACK -
124
Experiment ID244
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry[Q-TOF]
PubMed ID 22148876   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of microvesicles derived from human mesenchymal stem cells
AuthorsKim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW
Journal name J Proteome Res
Publication year2011
SampleMesenchymal stem cells
Sample nameMesenchymal stem cells - Rep 1
Isolation/purification methodsDifferential centrifugation
Ultrafiltration
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry[QTOF]
EV-TRACK -
125
Experiment ID310
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry[Q-TOF]
PubMed ID 22148876   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of microvesicles derived from human mesenchymal stem cells
AuthorsKim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW
Journal name J Proteome Res
Publication year2011
SampleMesenchymal stem cells
Sample nameMesenchymal stem cells - Rep 2
Isolation/purification methodsDifferential centrifugation
Ultrafiltration
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry[QTOF]
EV-TRACK -
126
Experiment ID311
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry[Q-TOF]
PubMed ID 22148876   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of microvesicles derived from human mesenchymal stem cells
AuthorsKim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW
Journal name J Proteome Res
Publication year2011
SampleMesenchymal stem cells
Sample nameMesenchymal stem cells - Rep 3
Isolation/purification methodsDifferential centrifugation
Ultrafiltration
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry[QTOF]
EV-TRACK -
127
Experiment ID25
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 15111327   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of exosomes secreted by human mesothelioma cells.
AuthorsHegmans JP, Bard MP, Hemmes A, Luider TM, Kleijmeer MJ, Prins JB, Zitvogel L, Burgers SA, Hoogsteden HC, Lambrecht BN.
Journal name AJP
Publication year2004
SampleMesothelioma cells
Sample namePMR-MM7
PMR-MM8
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [MALDI TOF]
Western blotting
EV-TRACK -
128
Experiment ID467
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 23000592   
OrganismHomo sapiens
Experiment descriptionIn-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts.
AuthorsLe Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G.
Journal name J Proteomics
Publication year2012
SampleNeonatal myoblast cells
Sample namePatient of developmental heart defect_exosome-Neonatal myoblast cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
129
Experiment ID468
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 23000592   
OrganismHomo sapiens
Experiment descriptionIn-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts.
AuthorsLe Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G.
Journal name J Proteomics
Publication year2012
SampleNeonatal myoblast cells
Sample namePatient of developmental heart defect_microparticle-Neonatal myoblast cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
130
Experiment ID526
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 23660474   
OrganismHomo sapiens
Experiment descriptionHeterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.
AuthorsDalli J, Montero Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M.
Journal name Mol Cell Proteomics
Publication year2013
SampleNeutrophils
Sample nameStimulated in fluid phase-Neutrophil
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
131
Experiment ID527
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 23660474   
OrganismHomo sapiens
Experiment descriptionHeterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.
AuthorsDalli J, Montero Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M.
Journal name Mol Cell Proteomics
Publication year2013
SampleNeutrophils
Sample nameStimulated in immobile phase-Neutrophil
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
132
Experiment ID428
Identified moleculeprotein
Extracellular vesicle typeMatrix vesicles
Identification method Mass spectrometry
PubMed ID 21515422   
OrganismHomo sapiens
Experiment descriptionProteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells.
AuthorsThouverey C, Malinowska A, Balcerzak M, Strzelecka-Kiliszek A, Buchet R, Dadlez M, Pikula S.
Journal name J Proteomics
Publication year2011
SampleOsteosarcoma cells
Sample nameNormal-Osteosarcoma cell (Saos-2 ATCC HTB-85)
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
133
Experiment ID492
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 23333927   
OrganismHomo sapiens
Experiment descriptionCharacterization and proteomic analysis of ovarian cancer-derived exosomes.
AuthorsLiang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year2013
SampleOvarian cancer cells
Sample nameIGROV1
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130002: EV-METRIC:67%, 56%
134
Experiment ID493
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 23333927   
OrganismHomo sapiens
Experiment descriptionCharacterization and proteomic analysis of ovarian cancer-derived exosomes.
AuthorsLiang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year2013
SampleOvarian cancer cells
Sample nameOVCAR-3
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130002: EV-METRIC:67%, 56%
135
Experiment ID626
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleOvarian cancer cells
Sample nameIGROV1
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
136
Experiment ID627
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleOvarian cancer cells
Sample nameOVCAR-3
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
137
Experiment ID630
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleOvarian cancer cells
Sample nameOVCAR-8
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
138
Experiment ID631
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleOvarian cancer cells
Sample nameSK-OV-3
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
139
Experiment ID992
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24434149   
OrganismHomo sapiens
Experiment descriptionIn-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
AuthorsSinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T.
Journal name Biochem Biophys Res Commun.
Publication year2014
SampleOvarian cancer cells
Sample nameOVCAR3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140099: EV-METRIC:44%
140
Experiment ID993
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24434149   
OrganismHomo sapiens
Experiment descriptionIn-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
AuthorsSinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T.
Journal name Biochem Biophys Res Commun.
Publication year2014
SampleOvarian cancer cells
Sample nameOVCAR433
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140099: EV-METRIC:44%
141
Experiment ID994
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24434149   
OrganismHomo sapiens
Experiment descriptionIn-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
AuthorsSinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T.
Journal name Biochem Biophys Res Commun.
Publication year2014
SampleOvarian cancer cells
Sample nameOVCAR5
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140099: EV-METRIC:44%
142
Experiment ID995
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24434149   
OrganismHomo sapiens
Experiment descriptionIn-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
AuthorsSinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T.
Journal name Biochem Biophys Res Commun.
Publication year2014
SampleOvarian cancer cells
Sample nameSKOV3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140099: EV-METRIC:44%
143
Experiment ID1135
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 23861904   
OrganismHomo sapiens
Experiment descriptionExosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.
AuthorsSalomon C, Ryan J, Sobrevia L, Kobayashi M, Ashman K, Mitchell M, Rice GE.
Journal name PLoS One
Publication year2013
SamplePlacental mesenchymal stem cells
Sample namepMSC's in 1% Oxygen
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Flotation density1.12 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130055: EV-METRIC:33%
144
Experiment ID443
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 22329422   
OrganismHomo sapiens
Experiment descriptionQuantitative proteome profiling of normal human circulating microparticles.
AuthorsØstergaard O, Nielsen CT, Iversen LV, Jacobsen S, Tanassi JT, Heegaard NH.
Journal name J Proteome Res
Publication year2012
SamplePlasma
Sample nameNormal-Platelet-poor plasma
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
145
Experiment ID473
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 23056467   
OrganismHomo sapiens
Experiment descriptionCause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy.
AuthorsAl Kaabi A, Traupe T, Stutz M, Buchs N, Heller M.
Journal name PLoS One
Publication year2012
SamplePlasma
Sample namePatients of external counterpulsation therapy-Blood
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
146
Experiment ID863
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 22046311   
OrganismMus musculus
Experiment descriptionExosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections
AuthorsMartin-Jaular L, Nakayasu ES, Ferrer M, Almeida IC, Del Portillo HA.
Journal name PLoS One
Publication year2011
SamplePlasma
Sample namePeripheral blood plasma - P. yoelii 17X infected
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
Mass spectrometry
EV-TRACK EV110102: EV-METRIC:25%, 25%
147
Experiment ID520
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 23601281   
OrganismHomo sapiens
Experiment descriptionProteomic characterization of human platelet-derived microparticles.
AuthorsCapriotti AL, Caruso G, Cavaliere C, Piovesana S, Samperi R, Laganà A.
Journal name Anal Chim Acta
Publication year2013
SamplePlatelets
Sample namePlatelets purifird from blood
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
148
Experiment ID138
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method
Mass spectrometry [QTOF]   Supporting data   MSS   
PubMed ID 22723089   
OrganismHomo sapiens
Experiment descriptionExosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.
AuthorsHosseini-Beheshti E, Guns ES.
Journal name MCP
Publication year2012
SampleProstate cancer cells
Sample nameDU145 - Rep 2
Isolation/purification methodsSucrose density gradient
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [QTOF]
EV-TRACK EV120018: EV-METRIC:38%
149
Experiment ID277
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry [Q-TOF]
PubMed ID 22030351   
OrganismHomo sapiens
Experiment descriptionExpression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways
AuthorsInder KL, Zheng YZ, Davis MJ, Moon H, Loo D, Nguyen H, Clements JA, Parton RG, Foster LJ, Hill MM
Journal name MCP
Publication year2011
SampleProstate cancer cells
Sample namePC-3
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [QTOF]
EV-TRACK -
150
Experiment ID634
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleProstate cancer cells
Sample namePC-3
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -
151
Experiment ID887
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 25102470   
OrganismHomo sapiens
Experiment descriptionExamination of the specificity of tumor cell derived exosomes with tumor cells in vitro
AuthorsSmyth TJ, Redzic JS, Graner MW, Anchordoquy TJ.
Journal name Biochim Biophys Acta
Publication year2014
SampleProstate cancer cells
Sample namePC3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.10-1.20 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140013: EV-METRIC:56%
152
Experiment ID963
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 25844599   
OrganismHomo sapiens
Experiment descriptionMolecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
AuthorsKharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year2015
SampleProstate cancer cells
Sample nameDU145 Tax-Sen
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.12-1.19 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV150027: EV-METRIC:11%, 56%
153
Experiment ID964
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 25844599   
OrganismHomo sapiens
Experiment descriptionMolecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
AuthorsKharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year2015
SampleProstate cancer cells
Sample nameDU145 Tax-Res
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.13-1.18 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV150027: EV-METRIC:11%, 56%
154
Experiment ID1113
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24391718   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
AuthorsDuijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G.
Journal name PLoS One
Publication year2013
SampleProstate cancer cells
Sample nameVCaP- replicate 1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130038: EV-METRIC:33%
155
Experiment ID1114
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24391718   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
AuthorsDuijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G.
Journal name PLoS One
Publication year2013
SampleProstate cancer cells
Sample nameVCaP- replicate 2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130038: EV-METRIC:33%
156
Experiment ID1115
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24391718   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
AuthorsDuijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G.
Journal name PLoS One
Publication year2013
SampleProstate cancer cells
Sample nameVCaP- replicate 3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130038: EV-METRIC:33%
157
Experiment ID1260
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24371517   
OrganismHomo sapiens
Experiment descriptionExosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
AuthorsBijnsdorp IV, Geldof AA, Lavaei M, Piersma SR, van Moorselaar RJ, Jimenez CR.
Journal name J Extracell Vesicles.
Publication year2013
SampleProstate cancer cells
Sample nameLNCaP
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV130168: EV-METRIC:11%, 11%
158
Experiment ID1261
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24371517   
OrganismHomo sapiens
Experiment descriptionExosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
AuthorsBijnsdorp IV, Geldof AA, Lavaei M, Piersma SR, van Moorselaar RJ, Jimenez CR.
Journal name J Extracell Vesicles.
Publication year2013
SampleProstate cancer cells
Sample namePC3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV130168: EV-METRIC:11%, 11%
159
Experiment ID1104
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24391718   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
AuthorsDuijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G.
Journal name PLoS One
Publication year2013
SampleProstate epithelial cells
Sample namePNT2C2- replicate 1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130038: EV-METRIC:33%
160
Experiment ID1105
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24391718   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
AuthorsDuijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G.
Journal name PLoS One
Publication year2013
SampleProstate epithelial cells
Sample namePNT2C2- replicate 2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130038: EV-METRIC:33%
161
Experiment ID1106
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24391718   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
AuthorsDuijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G.
Journal name PLoS One
Publication year2013
SampleProstate epithelial cells
Sample namePNT2C2- replicate 3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130038: EV-METRIC:33%
162
Experiment ID1107
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24391718   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
AuthorsDuijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G.
Journal name PLoS One
Publication year2013
SampleProstate epithelial cells
Sample nameRWPE-1- replicate 1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130038: EV-METRIC:33%
163
Experiment ID1108
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24391718   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
AuthorsDuijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G.
Journal name PLoS One
Publication year2013
SampleProstate epithelial cells
Sample nameRWPE-1- replicate 2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130038: EV-METRIC:33%
164
Experiment ID1109
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24391718   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
AuthorsDuijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G.
Journal name PLoS One
Publication year2013
SampleProstate epithelial cells
Sample nameRWPE-1- replicate 3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130038: EV-METRIC:33%
165
Experiment ID376
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 18346024   
OrganismHomo sapiens
Experiment descriptionThe proteome of red cell membranes and vesicles during storage in blood bank conditions.
AuthorsBosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ.
Journal name Transfusion
Publication year2008
SampleRed blood cells
Sample nameMicrovesicle, Storage day 21-Red blood cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
166
Experiment ID377
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 18346024   
OrganismHomo sapiens
Experiment descriptionThe proteome of red cell membranes and vesicles during storage in blood bank conditions.
AuthorsBosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ.
Journal name Transfusion
Publication year2008
SampleRed blood cells
Sample nameMicrovesicle, Storage day 3-Red blood cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
167
Experiment ID378
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 18346024   
OrganismHomo sapiens
Experiment descriptionThe proteome of red cell membranes and vesicles during storage in blood bank conditions.
AuthorsBosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ.
Journal name Transfusion
Publication year2008
SampleRed blood cells
Sample nameMicrovesicle, Storage day 42-Red blood cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
168
Experiment ID379
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 18346024   
OrganismHomo sapiens
Experiment descriptionThe proteome of red cell membranes and vesicles during storage in blood bank conditions.
AuthorsBosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ.
Journal name Transfusion
Publication year2008
SampleRed blood cells
Sample nameNanovesicle, Storage day 21-Red blood cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
169
Experiment ID380
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 18346024   
OrganismHomo sapiens
Experiment descriptionThe proteome of red cell membranes and vesicles during storage in blood bank conditions.
AuthorsBosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ.
Journal name Transfusion
Publication year2008
SampleRed blood cells
Sample nameNanovesicle, Storage day 3-Red blood cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
170
Experiment ID381
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 18346024   
OrganismHomo sapiens
Experiment descriptionThe proteome of red cell membranes and vesicles during storage in blood bank conditions.
AuthorsBosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ.
Journal name Transfusion
Publication year2008
SampleRed blood cells
Sample nameNanovesicle, Storage day 42-Red blood cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
171
Experiment ID1095
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24976626   
OrganismHomo sapiens
Experiment descriptionExosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells.
AuthorsGildea JJ, Seaton JE, Victor KG, Reyes CM, Bigler Wang D, Pettigrew AC, Courtner CE, Shah N, Tran HT, Van Sciver RE, Carlson JM, Felder RA.
Journal name Clin Biochem
Publication year2014
SampleRenal proximal tubule cells
Sample namei16
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Immunoaffinity
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140335: EV-METRIC:14%
172
Experiment ID1256
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24400796   
OrganismHomo sapiens
Experiment descriptionExosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.
AuthorsKang GY, Bang JY, Choi AJ, Yoon J, Lee WC, Choi S, Yoon S, Kim HC, Baek JH, Park HS, Lim HJ, Chung H.
Journal name J Proteome Res.
Publication year2014
SampleRetinal pigment epithelial cells
Sample nameARPE-19
Isolation/purification methodsExoQuick
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140174: EV-METRIC:13%, 13%
173
Experiment ID66
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 19199708   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
AuthorsGonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year2009
SampleSaliva
Sample nameSaliva
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
Western blotting
Immunoelectron microscopy
EV-TRACK -
174
Experiment ID410
Identified moleculemRNA
Extracellular vesicle typeExosomes/Membrane vesicles
Identification method Microarray
PubMed ID 20052414   
OrganismHomo sapiens
Experiment descriptionNanostructural and transcriptomic analyses of human saliva derived exosomes.
AuthorsPalanisamy V, Sharma S, Deshpande A, Zhou H, Gimzewski J, Wong DT.
Journal name PLoS One
Publication year2010
SampleSaliva
Sample nameNormal-Saliva
Isolation/purification methods-
Flotation density-
Molecules identified in the studymRNA
Methods used in the studyMicroarray
EV-TRACK EV100049: EV-METRIC:22%
175
Experiment ID367
Identified moleculeprotein
Extracellular vesicle typeProstasomes
Identification method Mass spectrometry
PubMed ID 12746840   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of human prostasomes.
AuthorsUtleg AG, Yi EC, Xie T, Shannon P, White JT, Goodlett DR, Hood L, Lin B.
Journal name Prostate
Publication year2003
SampleSeminal fluid
Sample nameNormal donors-Seminal fluid
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
176
Experiment ID389
Identified moleculeprotein
Extracellular vesicle typeExosomes/Prostasomes
Identification method Mass spectrometry
PubMed ID 18819103   
OrganismHomo sapiens
Experiment descriptionStructural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen.
AuthorsPoliakov A, Spilman M, Dokland T, Amling CL, Mobley JA.
Journal name Prostate
Publication year2009
SampleSeminal fluid
Sample nameNormal donors-Seminal fluid
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
177
Experiment ID1222
Identified moleculeprotein
Extracellular vesicle typeProstasomes
Identification method Mass spectrometry
PubMed ID 26272980   
OrganismHomo sapiens
Experiment descriptionProteomic Profiling of Detergent Resistant Membranes (Lipid Rafts) of Prostasomes
AuthorsDubois L, Ronquist KK, Ek B, Ronquist G, Larsson A.
Journal name Mol Cell Proteomics
Publication year2015
SampleSeminal plasma
Sample nameSeminal plasma
Isolation/purification methodsUltracentrifugation
Density gradient centrifugation
Flotation density1.13.1.19 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150039: EV-METRIC:44%
178
Experiment ID1138
Identified moleculeprotein
Extracellular vesicle typeProstasomes
Identification method Mass spectrometry
PubMed ID 23707955   
OrganismHomo sapiens
Experiment descriptionProstasomes from four different species are able to produce extracellular adenosine triphosphate (ATP).
AuthorsRonquist KG, Ek B, Morrell J, Stavreus-Evers A, Ströolst B, Humblot P, Ronquist G, Larsson A.
Journal name Biochim Biophys Acta
Publication year2013
SampleSeminal plasma
Sample namenormal male
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1-1.5 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130152: EV-METRIC:14%, 14%
179
Experiment ID1021
Identified moleculeprotein
Extracellular vesicle typeProstasomes
Identification method Mass spectrometry
PubMed ID 20332430   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of prostate cancer metastasis-derived prostasomes.
AuthorsRonquist KG, Ronquist G, Larsson A, Carlsson L.
Journal name Anticancer Res.
Publication year2010
SampleSkeletal tissue
Sample nameSkeletal metastases - prostate cancer
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV100086: EV-METRIC:14%
180
Experiment ID411
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 20124223   
OrganismHomo sapiens
Experiment descriptionHypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
AuthorsPark JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year2010
SampleSquamous carcinoma cells
Sample nameSquamous carcinoma cell (A431)
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV100050: EV-METRIC:22%
181
Experiment ID1009
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 23185418   
OrganismHomo sapiens
Experiment descriptionImproved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases.
AuthorsGyö B, Szabó, TuriáL, Wright M, Herczeg P, Léczi Z, Kittel A, PolgáA, TóK, Déalvi B, ZelenáG, Böz I, Carr B, Nagy G, Véy K, Gay S, Falus A, BuzáEI.
Journal name PLoS One.
Publication year2012
SampleSynovial fluid
Sample namesynovial fluid - patient with osteoarthritis (OA)
Isolation/purification methodsFiltration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
FACS
EV-TRACK EV120104: EV-METRIC:29%
182
Experiment ID1010
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 23185418   
OrganismHomo sapiens
Experiment descriptionImproved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases.
AuthorsGyö B, Szabó, TuriáL, Wright M, Herczeg P, Léczi Z, Kittel A, PolgáA, TóK, Déalvi B, ZelenáG, Böz I, Carr B, Nagy G, Véy K, Gay S, Falus A, BuzáEI.
Journal name PLoS One.
Publication year2012
SampleSynovial fluid
Sample namesynovial fluid - patient with rheumatoid arthritis (RA)
Isolation/purification methodsFiltration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
FACS
EV-TRACK EV120104: EV-METRIC:29%
183
Experiment ID1011
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 23185418   
OrganismHomo sapiens
Experiment descriptionImproved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases.
AuthorsGyö B, Szabó, TuriáL, Wright M, Herczeg P, Léczi Z, Kittel A, PolgáA, TóK, Déalvi B, ZelenáG, Böz I, Carr B, Nagy G, Véy K, Gay S, Falus A, BuzáEI.
Journal name PLoS One.
Publication year2012
SampleSynovial fluid
Sample namesynovial fluid - patient with juvenile idiopathic arthritis (JIA)
Isolation/purification methodsFiltration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
FACS
EV-TRACK EV120104: EV-METRIC:29%
184
Experiment ID306
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry [MALDI TOF/TOF]
Mass spectrometry [Q-TOF]
PubMed ID 16342139   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization
AuthorsMiguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet JM, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L
Journal name Proteomics
Publication year2006
SampleT cells
Sample nameCEM T cell - PHA activation
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [MALDI TOF/TOF]
Mass spectrometry [QTOF]
EV-TRACK -
185
Experiment ID307
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry [MALDI TOF/TOF]
Mass spectrometry [Q-TOF]
PubMed ID 16342139   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization
AuthorsMiguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet JM, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L
Journal name Proteomics
Publication year2006
SampleT cells
Sample nameCEM T cell - ActD activation
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [MALDI TOF/TOF]
Mass spectrometry [QTOF]
EV-TRACK -
186
Experiment ID710
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 28811610   
OrganismHomo sapiens
Experiment descriptionAntibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.
AuthorsNéth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI.
Journal name Sci Rep
Publication year2017
SampleT cells
Sample nameJurkat cells - Activated
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170063: EV-METRIC:75%, 75%
187
Experiment ID711
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 28811610   
OrganismHomo sapiens
Experiment descriptionAntibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.
AuthorsNéth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI.
Journal name Sci Rep
Publication year2017
SampleT cells
Sample nameJurkat cells - Activated
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170063: EV-METRIC:75%, 75%
188
Experiment ID715
Identified moleculeprotein
Extracellular vesicle typeApoptotic bodies
Identification method Mass spectrometry
PubMed ID 28811610   
OrganismHomo sapiens
Experiment descriptionAntibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.
AuthorsNéth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI.
Journal name Sci Rep
Publication year2017
SampleT cells
Sample nameJurkat cells - Apoptotic
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170063: EV-METRIC:75%, 75%
189
Experiment ID1004
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 23463506   
OrganismHomo sapiens
Experiment descriptionThe intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.
AuthorsPerez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartíS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó
Journal name J Biol Chem.
Publication year2013
SampleT cells
Sample nameT lymphoblasts - exosomes pulldown with CD81 as a bait
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV130110: EV-METRIC:22%
190
Experiment ID1005
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 23463506   
OrganismHomo sapiens
Experiment descriptionThe intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.
AuthorsPerez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartíS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó
Journal name J Biol Chem.
Publication year2013
SampleT cells
Sample nameT lymphoblasts - exosomes pulldown with EWI-2 as a bait
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV130110: EV-METRIC:22%
191
Experiment ID1008
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 23463506   
OrganismHomo sapiens
Experiment descriptionThe intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.
AuthorsPerez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartíS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó
Journal name J Biol Chem.
Publication year2013
SampleT cells
Sample nameT lymphoblasts
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130110: EV-METRIC:22%
192
Experiment ID118
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Western blotting
PubMed ID 21362503   
OrganismHomo sapiens
Experiment descriptionProtein profile of exosomes from trabecular meshwork cells.
AuthorsStamer WD, Hoffman EA, Luther JM, Hachey DL, Schey KL.
Journal name JOP
Publication year2011
SampleTabecular meshwork cells
Sample nameTabecular meshwork cells
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density1.07-1.2 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
Western blotting
EV-TRACK EV110011: EV-METRIC:33%, 33%, 56%
193
Experiment ID538
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 23844026   
OrganismHomo sapiens
Experiment descriptionCharacterization of human thymic exosomes.
AuthorsSkogberg G, Gudmundsdottir J, van der Post S, Sandström K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year2013
SampleThymus
Sample nameNormal-Thymus
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130018: EV-METRIC:63%
194
Experiment ID34
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 19190083   
OrganismHomo sapiens
Experiment descriptionCharacterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.
AuthorsKesimer M, Scull M, Brighton B, Demaria G, Burns K, O'Neal W, Pickles RJ, Sheehan JK
Journal name FASEB
Publication year2009
SampleTracheobronchial cells
Sample nameTracheobronchial epithelial cells
Isolation/purification methodsDifferential centrifugation
Filtration
Sucrose density gradient
Flotation density1.16 -1.18 g/mL
Molecules identified in the studyProtein
mRNA
Methods used in the studyMass spectrometry [QTOF]
Western blotting
Immunoelectron microscopy
FACS
EV-TRACK -
195
Experiment ID680
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29148239   
OrganismHomo sapiens
Experiment descriptionMetabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.
AuthorsBruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I.
Journal name Proteomics Clin Appl
Publication year2018
SampleUmblical cord mesenchymal stem cells
Sample namePreterm newborns- replicate 1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sonication
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
196
Experiment ID681
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29148239   
OrganismHomo sapiens
Experiment descriptionMetabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.
AuthorsBruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I.
Journal name Proteomics Clin Appl
Publication year2018
SampleUmblical cord mesenchymal stem cells
Sample namePreterm newborns- replicate 2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sonication
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
197
Experiment ID682
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29148239   
OrganismHomo sapiens
Experiment descriptionMetabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.
AuthorsBruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I.
Journal name Proteomics Clin Appl
Publication year2018
SampleUmblical cord mesenchymal stem cells
Sample namePreterm newborns- replicate 3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sonication
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
198
Experiment ID683
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29148239   
OrganismHomo sapiens
Experiment descriptionMetabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.
AuthorsBruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I.
Journal name Proteomics Clin Appl
Publication year2018
SampleUmblical cord mesenchymal stem cells
Sample nameTerm infants- replicate 1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sonication
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
199
Experiment ID684
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29148239   
OrganismHomo sapiens
Experiment descriptionMetabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.
AuthorsBruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I.
Journal name Proteomics Clin Appl
Publication year2018
SampleUmblical cord mesenchymal stem cells
Sample nameTerm infants- replicate 2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sonication
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
200
Experiment ID685
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29148239   
OrganismHomo sapiens
Experiment descriptionMetabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.
AuthorsBruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I.
Journal name Proteomics Clin Appl
Publication year2018
SampleUmblical cord mesenchymal stem cells
Sample nameTerm infants- replicate 3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sonication
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
201
Experiment ID57
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Western blotting
PubMed ID 17700640   
OrganismHomo sapiens
Experiment descriptionCD24 is a marker of exosomes secreted into urine and amniotic fluid.
AuthorsKeller S, Rupp C, Stoeck A, Runz S, Fogel M, Lugert S, Hager HD, Abdel-Bakky MS, Gutwein P, Altevogt P
Journal name KI
Publication year2007
SampleUrine
Sample nameUrine - Normal
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density1.05-1.15 g/mL
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
FACS
EV-TRACK -
202
Experiment ID63
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 19056867   
OrganismHomo sapiens
Experiment descriptionLarge-scale proteomics and phosphoproteomics of urinary exosomes.
AuthorsGonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year2009
SampleUrine
Sample nameUrine - Normal
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
Western blotting
EV-TRACK -
203
Experiment ID119
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Western blotting
PubMed ID 21362503   
OrganismHomo sapiens
Experiment descriptionProtein profile of exosomes from trabecular meshwork cells.
AuthorsStamer WD, Hoffman EA, Luther JM, Hachey DL, Schey KL.
Journal name JOP
Publication year2011
SampleUrine
Sample nameUrine - Normal
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
Western blotting
EV-TRACK EV110011: EV-METRIC:33%, 33%, 56%
204
Experiment ID390
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane particles
Identification method Mass spectrometry
PubMed ID 19158352   
OrganismHomo sapiens
Experiment descriptionCharacterization of PKD protein-positive exosome-like vesicles.
AuthorsHogan MC, Manganelli L, Woollard JR, Masyuk AI, Masyuk TV, Tammachote R, Huang BQ, Leontovich AA, Beito TG, Madden BJ, Charlesworth MC, Torres VE, LaRusso NF, Harris PC, Ward CJ.
Journal name J Am Soc Nephrol
Publication year2009
SampleUrine
Sample namePatients of autosomal recessive polycystic kidney disease-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
205
Experiment ID437
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
Identification method Mass spectrometry
PubMed ID 22106071   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
AuthorsWang Z, Hill S, Luther JM, Hachey DL, Schey KL.
Journal name Proteomics
Publication year2012
SampleUrine
Sample nameNormal donors-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120168: EV-METRIC:14%
206
Experiment ID444
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 22418980   
OrganismHomo sapiens
Experiment descriptionA multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
AuthorsRaj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year2012
SampleUrine
Sample nameNormal_high density-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120083: EV-METRIC:22%
207
Experiment ID445
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 22418980   
OrganismHomo sapiens
Experiment descriptionA multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
AuthorsRaj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year2012
SampleUrine
Sample nameNormal_low density-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120083: EV-METRIC:22%
208
Experiment ID478
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
Identification method Mass spectrometry
PubMed ID 23082778   
OrganismHomo sapiens
Experiment descriptionComparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients.
AuthorsChen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT.
Journal name J Proteome Res
Publication year2012
SampleUrine
Sample namePatients of bladder cancer-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120030: EV-METRIC:33%
209
Experiment ID479
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
Identification method Mass spectrometry
PubMed ID 23082778   
OrganismHomo sapiens
Experiment descriptionComparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients.
AuthorsChen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT.
Journal name J Proteome Res
Publication year2012
SampleUrine
Sample namePatients of hernia-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120030: EV-METRIC:33%
210
Experiment ID498
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
Identification method Mass spectrometry
PubMed ID 23376485   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of podocyte exosome-enriched fraction from normal human urine.
AuthorsPrunotto M, Farina A, Lane L, Pernin A, Schifferli J, Hochstrasser DF, Lescuyer P, Moll S.
Journal name J Proteomics
Publication year2013
SampleUrine
Sample nameNormal-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130051: EV-METRIC:38%
211
Experiment ID507
Identified moleculeprotein
Extracellular vesicle typeExosomes/Nanovesicles
Identification method Mass spectrometry
PubMed ID 23511837   
OrganismHomo sapiens
Experiment descriptionDifferential protein profiling of renal cell carcinoma urinary exosomes.
AuthorsRaimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M.
Journal name Mol Biosyst
Publication year2013
SampleUrine
Sample nameNormal-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130016: EV-METRIC:44%
212
Experiment ID508
Identified moleculeprotein
Extracellular vesicle typeExosomes/Nanovesicles
Identification method Mass spectrometry
PubMed ID 23511837   
OrganismHomo sapiens
Experiment descriptionDifferential protein profiling of renal cell carcinoma urinary exosomes.
AuthorsRaimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M.
Journal name Mol Biosyst
Publication year2013
SampleUrine
Sample nameRenal cell carcinoma patient-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130016: EV-METRIC:44%
213
Experiment ID512
Identified moleculeprotein
Extracellular vesicle typeExosomes/Microvesicles
Identification method Mass spectrometry
PubMed ID 23533145   
OrganismHomo sapiens
Experiment descriptionIn-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
AuthorsPrincipe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR.
Journal name Proteomics
Publication year2013
SampleUrine
Sample nameLow-grade prostate cancer patient-Expressed prostatic secretions in urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130224: EV-METRIC:14%
214
Experiment ID513
Identified moleculeprotein
Extracellular vesicle typeExosomes/Microvesicles
Identification method Mass spectrometry
PubMed ID 23533145   
OrganismHomo sapiens
Experiment descriptionIn-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
AuthorsPrincipe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR.
Journal name Proteomics
Publication year2013
SampleUrine
Sample nameNormal-Expressed prostatic secretions in urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130224: EV-METRIC:14%
215
Experiment ID725
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 25471207   
OrganismHomo sapiens
Experiment descriptionIntraluminal proteome and peptidome of human urinary extracellular vesicles.
AuthorsLiu X, Chinello C, Musante L, Cazzaniga M, Tataruch D, Calzaferri G, James Smith A, De Sio G, Magni F, Zou H, Holthofer H.
Journal name Proteomics Clin Appl.
Publication year2015
SampleUrine
Sample nameNormal crude urine- Trypsinized
Isolation/purification methodsDifferential centrifugation
Hydrostatic filtration dialysis
Ultrafiltration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140189: EV-METRIC:25%
216
Experiment ID751
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29988836   
OrganismHomo sapiens
Experiment descriptionUltrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine
AuthorsOeyen E, Van Mol K, Baggerman G, Willems H, Boonen K, Rolfo C, Pauwels P, Jacobs A, Schildermans K, Cho WC, Mertens I.
Journal name J Extracell Vesicles
Publication year2018
SampleUrine
Sample nameUrine - Fraction 8 and 9 pooled
Isolation/purification methodsFiltration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170025: EV-METRIC:62%
217
Experiment ID1027
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24211404   
OrganismHomo sapiens
Experiment descriptionDiabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis.
AuthorsZubiri I, Posada-Ayala M, Sanz-Maroto A, Calvo E, Martin-Lorenzo M, Gonzalez-Calero L, de la Cuesta F, Lopez JA, Fernandez-Fernandez B, Ortiz A, Vivanco F, Alvarez-Llamas G.
Journal name J Proteomics.
Publication year2014
SampleUrine
Sample nameUrine - Diabetic nephropathy (DN) patients
Isolation/purification methodsUltracentrifugation
ExoQuick
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140245: EV-METRIC:22%, 25%, 22%
218
Experiment ID1161
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 22641613   
OrganismHomo sapiens
Experiment descriptionApplication of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation.
AuthorsPisitkun T, Gandolfo MT, Das S, Knepper MA, Bagnasco SM.
Journal name Proteomics Clin Appl
Publication year2012
SampleUrine
Sample nameRenal allograft recipient with cell-mediated rejection
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120152: EV-METRIC:14%
219
Experiment ID906
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29207636   
OrganismHomo sapiens
Experiment descriptionCharacterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer
AuthorsSilvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF.
Journal name Oncotarget
Publication year2017
SampleUrothelial cells
Sample nameSVHUC
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
220
Experiment ID931
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 29207636   
OrganismHomo sapiens
Experiment descriptionCharacterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.
AuthorsSilvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF.
Journal name Oncotarget
Publication year2017
SampleUrothelial cells
Sample nameSVHUC
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%