Gene description for ACTBL2
Gene name actin beta like 2
Gene symbol ACTBL2
Other names/aliases ACT
Species Homo sapiens
 Experiment description of studies that identified ACTBL2 in Urine

1
Experiment ID63
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 19056867   
OrganismHomo sapiens
Experiment descriptionLarge-scale proteomics and phosphoproteomics of urinary exosomes.
AuthorsGonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year2009
SampleUrine
Sample nameUrine - Normal
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
Western blotting
EV-TRACK -

2
Experiment ID178
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method Mass spectrometry [MALDI TOF]
PubMed ID 20686450   
OrganismHomo sapiens
Experiment descriptionComparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome
AuthorsRood IM, Deegens JK, Merchant ML, Tamboer WP, Wilkey DW, Wetzels JF, Klein JB
Journal name Kidney Int
Publication year2010
SampleUrine
Sample nameUrine - NM UF
Isolation/purification methodsDifferential centrifugation
Ultrafiltration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry [MALDI TOF]
EV-TRACK EV100026: EV-METRIC:33%, 25%, 44%

3
Experiment ID179
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method Mass spectrometry [MALDI TOF]
PubMed ID 20686450   
OrganismHomo sapiens
Experiment descriptionComparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome
AuthorsRood IM, Deegens JK, Merchant ML, Tamboer WP, Wilkey DW, Wetzels JF, Klein JB
Journal name Kidney Int
Publication year2010
SampleUrine
Sample nameUrine - UC
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry [MALDI TOF]
EV-TRACK EV100026: EV-METRIC:33%, 25%, 44%

4
Experiment ID180
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method Mass spectrometry [MALDI TOF]
PubMed ID 20686450   
OrganismHomo sapiens
Experiment descriptionComparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome
AuthorsRood IM, Deegens JK, Merchant ML, Tamboer WP, Wilkey DW, Wetzels JF, Klein JB
Journal name Kidney Int
Publication year2010
SampleUrine
Sample nameUrine - SEC
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Size exclusion chromatography
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry [MALDI TOF]
EV-TRACK EV100026: EV-METRIC:33%, 25%, 44%

5
Experiment ID382
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 18373357   
OrganismHomo sapiens
Experiment descriptionIsolation and identification of potential urinary microparticle biomarkers of bladder cancer.
AuthorsSmalley DM, Sheman NE, Nelson K, Theodorescu D.
Journal name J Proteome Res
Publication year2008
SampleUrine
Sample nameNormal donors-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

6
Experiment ID383
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 18373357   
OrganismHomo sapiens
Experiment descriptionIsolation and identification of potential urinary microparticle biomarkers of bladder cancer.
AuthorsSmalley DM, Sheman NE, Nelson K, Theodorescu D.
Journal name J Proteome Res
Publication year2008
SampleUrine
Sample namePatients of bladder cancer-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

7
Experiment ID429
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 21595033   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
AuthorsMoon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC.
Journal name Proteomics
Publication year2011
SampleUrine
Sample nameNormal donors-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV110019: EV-METRIC:44%

8
Experiment ID430
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 21595033   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
AuthorsMoon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC.
Journal name Proteomics
Publication year2011
SampleUrine
Sample namePatients of basement membrane nephropathy-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV110019: EV-METRIC:44%

9
Experiment ID431
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 21595033   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
AuthorsMoon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC.
Journal name Proteomics
Publication year2011
SampleUrine
Sample namePatients of early IgA nephropathy-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV110019: EV-METRIC:44%

10
Experiment ID437
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22106071   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
AuthorsWang Z, Hill S, Luther JM, Hachey DL, Schey KL.
Journal name Proteomics
Publication year2012
SampleUrine
Sample nameNormal donors-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120168: EV-METRIC:14%

11
Experiment ID498
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23376485   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of podocyte exosome-enriched fraction from normal human urine.
AuthorsPrunotto M, Farina A, Lane L, Pernin A, Schifferli J, Hochstrasser DF, Lescuyer P, Moll S.
Journal name J Proteomics
Publication year2013
SampleUrine
Sample nameNormal-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130051: EV-METRIC:38%

12
Experiment ID751
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 29988836   
OrganismHomo sapiens
Experiment descriptionUltrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine
AuthorsOeyen E, Van Mol K, Baggerman G, Willems H, Boonen K, Rolfo C, Pauwels P, Jacobs A, Schildermans K, Cho WC, Mertens I.
Journal name J Extracell Vesicles
Publication year2018
SampleUrine
Sample nameUrine - Fraction 8 and 9 pooled
Isolation/purification methodsFiltration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV170025: EV-METRIC:62%

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