Gene description for PECAM1
Gene name	platelet and endothelial cell adhesion molecule 1
Gene symbol	PECAM1
Other names/aliases	CD31 CD31/EndoCAM GPIIA' PECA1 PECAM-1 endoCAM
Species	Homo sapiens
Experiment description of studies that identified PECAM1 in Endothelial cells
1 Experiment ID 223 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS Western blotting PubMed ID 10393703    Organism Homo sapiens Experiment description In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Authors Combes V, Simon AC, Grau GE, Arnoux D, Camoin L, Sabatier F, Mutin M, Sanmarco M, Sampol J, Dignat-George F Journal name J Clin Invest Publication year 1999 Sample Endothelial cells Sample name HUVECS Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study FACS Western blotting EV-TRACK -
2 Experiment ID 267 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 12757771    Organism Homo sapiens Experiment description Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Authors Jimenez JJ, Jy W, Mauro LM, Soderland C, Horstman LL, Ahn YS Journal name Thromb Res Publication year 2003 Sample Endothelial cells Sample name Brain microvascular endothelial cells - ACBRI 376 - Control TNF alpha GFD Isolation/purification methods Differential centrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -
3 Experiment ID 268 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 12757771    Organism Homo sapiens Experiment description Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Authors Jimenez JJ, Jy W, Mauro LM, Soderland C, Horstman LL, Ahn YS Journal name Thromb Res Publication year 2003 Sample Endothelial cells Sample name Glomerular microvascular endothelial cells - ACBRI 128 - Control TNF alpha GFD Isolation/purification methods Differential centrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -
4 Experiment ID 269 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 12757771    Organism Homo sapiens Experiment description Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Authors Jimenez JJ, Jy W, Mauro LM, Soderland C, Horstman LL, Ahn YS Journal name Thromb Res Publication year 2003 Sample Endothelial cells Sample name Coronary artery endothelial cells - ACBRI 377 - Control TNF alpha GFD Isolation/purification methods Differential centrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -
5 Experiment ID 385 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 18563738    Organism Homo sapiens Experiment description Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Authors Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. Journal name Proteomics Publication year 2008 Sample Endothelial cells Sample name Endothelial cells (HUVEC) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
6 Experiment ID 386 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 18563738    Organism Homo sapiens Experiment description Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Authors Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. Journal name Proteomics Publication year 2008 Sample Endothelial cells Sample name Treated by PAI-1-Endothelial cell (HUVEC) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
7 Experiment ID 387 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 18563738    Organism Homo sapiens Experiment description Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Authors Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. Journal name Proteomics Publication year 2008 Sample Endothelial cells Sample name Treated by TNF-alpha-Endothelial cells (HUVEC) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
8 Experiment ID 393 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 19369228    Organism Homo sapiens Experiment description Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Authors Prokopi M, Pula G, Mayr U, Devue C, Gallagher J, Xiao Q, Boulanger CM, Westwood N, Urbich C, Willeit J, Steiner M, Breuss J, Xu Q, Kiechl S, Mayr M. Journal name Blood Publication year 2009 Sample Endothelial cells Sample name Normal-Endothelial progenitor cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
9 Experiment ID 502 Identified molecule protein Extracellular vesicle type Membrane vesicles/Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23436686    Organism Homo sapiens Experiment description A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Authors Pallet N, Sirois I, Bell C, Hanafi LA, Hamelin K, Dieudé M, Rondeau C, Thibault P, Desjardins M, Hebert MJ. Journal name Proteomics Publication year 2013 Sample Endothelial cells Sample name Serum-starved-Human umbilical vascular endothelial cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130048: EV-METRIC:44%
10 Experiment ID 551 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 24009886    Organism Homo sapiens Experiment description Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Authors de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. Journal name J Extracell Vesicles Publication year 2012 Sample Endothelial cells Sample name Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120004: EV-METRIC:67%