Gene description for PECAM1
Gene name	platelet and endothelial cell adhesion molecule 1
Gene symbol	PECAM1
Other names/aliases	CD31 CD31/EndoCAM GPIIA' PECA1 PECAM-1 endoCAM
Species	Homo sapiens
Experiment description of studies that identified PECAM1 in Plasma
1 Experiment ID 218 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Immunoaffinity PubMed ID 10694520    Organism Homo sapiens Experiment description Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Authors Mallat Z, Benamer H, Hugel B, Benessiano J, Steg PG, Freyssinet JM, Tedgui A Journal name Circulation Publication year 2000 Sample Plasma Sample name Plasma - Stable angina Isolation/purification methods Immunoaffinity [Annexin-V] Flotation density - Molecules identified in the study Protein Methods used in the study Immunoaffinity EV-TRACK -
2 Experiment ID 219 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Immunoaffinity PubMed ID 10694520    Organism Homo sapiens Experiment description Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Authors Mallat Z, Benamer H, Hugel B, Benessiano J, Steg PG, Freyssinet JM, Tedgui A Journal name Circulation Publication year 2000 Sample Plasma Sample name Plasma - Acute coronary syndromes Isolation/purification methods Immunoaffinity [Annexin-V] Flotation density - Molecules identified in the study Protein Methods used in the study Immunoaffinity EV-TRACK -
3 Experiment ID 220 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Immunoaffinity PubMed ID 10694520    Organism Homo sapiens Experiment description Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Authors Mallat Z, Benamer H, Hugel B, Benessiano J, Steg PG, Freyssinet JM, Tedgui A Journal name Circulation Publication year 2000 Sample Plasma Sample name Plasma - Noncoronary heart disease Isolation/purification methods Immunoaffinity [Annexin-V] Flotation density - Molecules identified in the study Protein Methods used in the study Immunoaffinity EV-TRACK -
4 Experiment ID 224 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 10393703    Organism Homo sapiens Experiment description In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Authors Combes V, Simon AC, Grau GE, Arnoux D, Camoin L, Sabatier F, Mutin M, Sanmarco M, Sampol J, Dignat-George F Journal name J Clin Invest Publication year 1999 Sample Plasma Sample name Plasma - Normal Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Confocal microscopy FACS EV-TRACK -
5 Experiment ID 241 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 16192427    Organism Homo sapiens Experiment description Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure Authors Amabile N, Guén AP, Leroyer A, Mallat Z, Nguyen C, Boddaert J, London GM, Tedgui A, Boulanger CM Journal name J Am Soc Nephrol Publication year 2005 Sample Plasma Sample name Plasma - End-stage renal failure patients Isolation/purification methods Differential centrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -
6 Experiment ID 279 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 16192427    Organism Homo sapiens Experiment description Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure Authors Amabile N, Guén AP, Leroyer A, Mallat Z, Nguyen C, Boddaert J, London GM, Tedgui A, Boulanger CM Journal name J Am Soc Nephrol Publication year 2005 Sample Plasma Sample name Plasma - Normal Isolation/purification methods Differential centrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -
7 Experiment ID 296 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 12796750    Organism Homo sapiens Experiment description High levels of circulating endothelial microparticles in patients with acute coronary syndromes Authors Bernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS Journal name Am Heart J Publication year 2003 Sample Plasma Sample name Plasma - Normal Isolation/purification methods Differential centrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -
8 Experiment ID 297 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 12796750    Organism Homo sapiens Experiment description High levels of circulating endothelial microparticles in patients with acute coronary syndromes Authors Bernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS Journal name Am Heart J Publication year 2003 Sample Plasma Sample name Plasma - Acute coronary syndrome Isolation/purification methods Differential centrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -
9 Experiment ID 298 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 12796750    Organism Homo sapiens Experiment description High levels of circulating endothelial microparticles in patients with acute coronary syndromes Authors Bernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS Journal name Am Heart J Publication year 2003 Sample Plasma Sample name Plasma - Coronary artery disease Isolation/purification methods Differential centrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -
10 Experiment ID 299 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 12796750    Organism Homo sapiens Experiment description High levels of circulating endothelial microparticles in patients with acute coronary syndromes Authors Bernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS Journal name Am Heart J Publication year 2003 Sample Plasma Sample name Plasma - Myocardial infarction Isolation/purification methods Differential centrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -
11 Experiment ID 284 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 12796750    Organism Homo sapiens Experiment description High levels of circulating endothelial microparticles in patients with acute coronary syndromes Authors Bernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS Journal name Am Heart J Publication year 2003 Sample Plasma Sample name Plasma - Stable angina Isolation/purification methods Differential centrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -
12 Experiment ID 285 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method FACS PubMed ID 12796750    Organism Homo sapiens Experiment description High levels of circulating endothelial microparticles in patients with acute coronary syndromes Authors Bernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS Journal name Am Heart J Publication year 2003 Sample Plasma Sample name Plasma - Unstable angina Isolation/purification methods Differential centrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -
13 Experiment ID 354 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [Orbitrap Velos] PubMed ID 24115447    Organism Homo sapiens Experiment description Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Authors Mathivanan,S. Journal name Proteomics Publication year 2013 Sample Plasma Sample name Plasma - Normal Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [Orbitrap Velos] Western blotting EV-TRACK EV130073: EV-METRIC:0%, 11%, 33%, 33%, 56%
14 Experiment ID 454 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 22669077    Organism Homo sapiens Experiment description The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation. Authors Bosman GJ, Lasonder E, Groenen-Döpp YA, Willekens FL, Werre JM. Journal name J Proteomics Publication year 2012 Sample Plasma Sample name Normal-Blood Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
15 Experiment ID 473 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 23056467    Organism Homo sapiens Experiment description Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy. Authors Al Kaabi A, Traupe T, Stutz M, Buchs N, Heller M. Journal name PLoS One Publication year 2012 Sample Plasma Sample name Patients of external counterpulsation therapy-Blood Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
16 Experiment ID 2329 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 32487994    Organism Homo sapiens Experiment description Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence Authors Toda H, Diaz-Varela M, Segui-Barber J, Roobsoong W, Baro B, Garcia-Silva S, Galiano A, Gualdrón-López M, Almeida ACG, Brito MAM, de Melo GC, Aparici-Herraiz I, Castro-Cavadía C, Monteiro WM, Borràs E, Sabidó E, Almeida IC, Chojnacki J, Martinez-Picado J, Calvo M, Armengol P, Carmona-Fonseca J, Yasnot MF, Lauzurica R, Marcilla A, Peinado H, Galinski MR, Lacerda MVG, Sattabongkot J, Fernandez-Becerra C, Del Portillo HA. Journal name Nat Commun Publication year 2020 Sample Plasma Sample name Healthy donors Isolation/purification methods Centrifugation Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry Flow cytometry EV-TRACK -
17 Experiment ID 2330 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 32487994    Organism Homo sapiens Experiment description Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence Authors Toda H, Diaz-Varela M, Segui-Barber J, Roobsoong W, Baro B, Garcia-Silva S, Galiano A, Gualdrón-López M, Almeida ACG, Brito MAM, de Melo GC, Aparici-Herraiz I, Castro-Cavadía C, Monteiro WM, Borràs E, Sabidó E, Almeida IC, Chojnacki J, Martinez-Picado J, Calvo M, Armengol P, Carmona-Fonseca J, Yasnot MF, Lauzurica R, Marcilla A, Peinado H, Galinski MR, Lacerda MVG, Sattabongkot J, Fernandez-Becerra C, Del Portillo HA. Journal name Nat Commun Publication year 2020 Sample Plasma Sample name Plasmodium vivax (Malaria) patients Isolation/purification methods Centrifugation Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry Flow cytometry EV-TRACK -
18 Experiment ID 2433 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 29320704    Organism Homo sapiens Experiment description Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Authors Whitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA. Journal name Cell Metab Publication year 2018 Sample Plasma Sample name Plasma Isolation/purification methods Centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
19 Experiment ID 2434 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 29320704    Organism Homo sapiens Experiment description Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Authors Whitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA. Journal name Cell Metab Publication year 2018 Sample Plasma Sample name Plasma Isolation/purification methods Centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
20 Experiment ID 2848 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35058437    Organism Homo sapiens Experiment description Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Authors El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H. Journal name Nat Commun Publication year 2022 Sample Plasma Sample name NWL-001 - Lung cancer patient Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry EV-TRACK -