Gene description for ACTA2
Gene name	actin alpha 2, smooth muscle
Gene symbol	ACTA2
Other names/aliases	ACTSA
Species	Homo sapiens
Experiment description of studies that identified ACTA2 in Urine
1 Experiment ID 13 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 15326289    Organism Homo sapiens Experiment description Identification and proteomic profiling of exosomes in human urine. Authors Pisitkun T, Shen RF, Knepper MA Journal name PNAS Publication year 2004 Sample Urine Sample name Urine - Normal Isolation/purification methods Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LCQ DECA XP] Western blotting EV-TRACK -
2 Experiment ID 178 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Mass spectrometry [MALDI TOF] PubMed ID 20686450    Organism Homo sapiens Experiment description Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Authors Rood IM, Deegens JK, Merchant ML, Tamboer WP, Wilkey DW, Wetzels JF, Klein JB Journal name Kidney Int Publication year 2010 Sample Urine Sample name Urine - NM UF Isolation/purification methods Differential centrifugation Ultrafiltration Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry [MALDI TOF] EV-TRACK EV100026: EV-METRIC:33%, 25%, 44%
3 Experiment ID 179 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Mass spectrometry [MALDI TOF] PubMed ID 20686450    Organism Homo sapiens Experiment description Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Authors Rood IM, Deegens JK, Merchant ML, Tamboer WP, Wilkey DW, Wetzels JF, Klein JB Journal name Kidney Int Publication year 2010 Sample Urine Sample name Urine - UC Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry [MALDI TOF] EV-TRACK EV100026: EV-METRIC:33%, 25%, 44%
4 Experiment ID 180 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Mass spectrometry [MALDI TOF] PubMed ID 20686450    Organism Homo sapiens Experiment description Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Authors Rood IM, Deegens JK, Merchant ML, Tamboer WP, Wilkey DW, Wetzels JF, Klein JB Journal name Kidney Int Publication year 2010 Sample Urine Sample name Urine - SEC Isolation/purification methods Differential centrifugation Ultracentrifugation Size exclusion chromatography Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry [MALDI TOF] EV-TRACK EV100026: EV-METRIC:33%, 25%, 44%
5 Experiment ID 382 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 18373357    Organism Homo sapiens Experiment description Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. Authors Smalley DM, Sheman NE, Nelson K, Theodorescu D. Journal name J Proteome Res Publication year 2008 Sample Urine Sample name Normal donors-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
6 Experiment ID 383 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 18373357    Organism Homo sapiens Experiment description Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. Authors Smalley DM, Sheman NE, Nelson K, Theodorescu D. Journal name J Proteome Res Publication year 2008 Sample Urine Sample name Patients of bladder cancer-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
7 Experiment ID 429 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 21595033    Organism Homo sapiens Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Authors Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. Journal name Proteomics Publication year 2011 Sample Urine Sample name Normal donors-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV110019: EV-METRIC:44%
8 Experiment ID 430 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 21595033    Organism Homo sapiens Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Authors Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. Journal name Proteomics Publication year 2011 Sample Urine Sample name Patients of basement membrane nephropathy-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV110019: EV-METRIC:44%
9 Experiment ID 431 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 21595033    Organism Homo sapiens Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Authors Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. Journal name Proteomics Publication year 2011 Sample Urine Sample name Patients of early IgA nephropathy-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV110019: EV-METRIC:44%
10 Experiment ID 478 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23082778    Organism Homo sapiens Experiment description Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Authors Chen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT. Journal name J Proteome Res Publication year 2012 Sample Urine Sample name Patients of bladder cancer-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120030: EV-METRIC:33%
11 Experiment ID 479 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23082778    Organism Homo sapiens Experiment description Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Authors Chen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT. Journal name J Proteome Res Publication year 2012 Sample Urine Sample name Patients of hernia-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120030: EV-METRIC:33%