Gene description for C4A
Gene name complement C4A (Rodgers blood group)
Gene symbol C4A
Other names/aliases C4
C4A2
C4A3
C4A4
C4A6
C4AD
C4S
CO4
CPAMD2
RG
Species Homo sapiens
 Experiment description of studies that identified C4A in Macrophage

1
Experiment ID1014
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22711894   
OrganismHomo sapiens
Experiment descriptionBiochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.
AuthorsKadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE.
Journal name J Immunol.
Publication year2012
SampleMacrophage
Sample nameMonocyte-derived macrophages - CHMP4/TSG101 pulldown exosomes
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyMass spectrometry
EV-TRACK EV120137: EV-METRIC:17%, 0%

2
Experiment ID1015
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22711894   
OrganismHomo sapiens
Experiment descriptionBiochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.
AuthorsKadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE.
Journal name J Immunol.
Publication year2012
SampleMacrophage
Sample nameMonocyte-derived macrophages - Myosin B pulldown exosomes
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyMass spectrometry
EV-TRACK EV120137: EV-METRIC:17%, 0%

3
Experiment ID1016
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22711894   
OrganismHomo sapiens
Experiment descriptionBiochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.
AuthorsKadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE.
Journal name J Immunol.
Publication year2012
SampleMacrophage
Sample nameMonocyte-derived macrophages - Rab 11
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyMass spectrometry
EV-TRACK EV120137: EV-METRIC:17%, 0%

4
Experiment ID1017
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22711894   
OrganismHomo sapiens
Experiment descriptionBiochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.
AuthorsKadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE.
Journal name J Immunol.
Publication year2012
SampleMacrophage
Sample nameMonocyte-derived macrophages - Vinculin/Talin pulldown exosomes
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyMass spectrometry
EV-TRACK EV120137: EV-METRIC:17%, 0%

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