Gene description for HSPA4 |
Gene name |
heat shock 70kDa protein 4 |
Gene symbol |
HSPA4 |
Other names/aliases |
APG-2 HS24/P52 HSPH2 RY hsp70 hsp70RY |
Species |
Homo sapiens |
Database cross references - HSPA4 |
Vesiclepedia |
VP_3308 |
ExoCarta |
ExoCarta_3308 |
Entrez Gene |
3308 |
HGNC |
5237 |
MIM |
601113 |
HSPA4 identified in extracellular vesicles derived from the following tissue/cell type |
adipocytes [Exosomes] More >>>
|
24513287
|
adipocytes [Exosomes] More >>>
|
24513287
|
Adipose tissue-derived stem cells [Exosomes] More >>>
|
29964051
|
Amniotic fluid [Exosomes] More >>>
|
17700640
|
Aqueous humor [Exosomes] More >>>
|
24400796
|
Ascites [Exosomes] More >>>
|
21601258
|
Ascites [Exosomes] More >>>
|
21601258
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Microparticles] More >>>
|
16342139
|
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles] More >>>
|
23818640
|
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles] More >>>
|
23818640
|
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles] More >>>
|
23818640
|
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles] More >>>
|
23818640
|
Bladder cancer cells [Extracellular vesicles] More >>>
|
29207636
|
Bladder cancer cells [Extracellular vesicles] More >>>
|
29207636
|
Brain cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Brain cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Brain cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Exosomes] More >>>
|
25102470
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchoalveolar lavage fluid [Exosomes] More >>>
|
20880880
|
Bronchoalveolar lavage fluid [Exosomes] More >>>
|
20880880
|
Chronic lymphocytic leukemia cells [Exosomes] More >>>
|
26100252
|
Chronic lymphocytic leukemia cells [Exosomes] More >>>
|
26100252
|
Chronic lymphocytic leukemia cells [Exosomes] More >>>
|
26100252
|
Colorectal cancer cells [Exosomes] More >>>
|
17956143
|
Colorectal cancer cells [Microvesicles] More >>>
|
19930720
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Membrane vesicles] More >>>
|
23585443
|
Colorectal cancer cells [Exosomes/Membrane vesicles] More >>>
|
23585443
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes] More >>>
|
24009881
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes] More >>>
|
24009881
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Colorectal cancer cells [Microvesicles] More >>>
|
28842968
|
Colorectal cancer cells [Microvesicles] More >>>
|
28842968
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
28842968
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
28842968
|
Dendritic cells [Microvesicles] More >>>
|
26858453
|
Dendritic cells [Microvesicles] More >>>
|
26858453
|
Dendritic cells [Exosomes] More >>>
|
26858453
|
Dendritic cells [Exosomes] More >>>
|
26858453
|
Dendritic cells [Extracellular vesicles] More >>>
|
26858453
|
Embryonic kidney cells [Exosomes] More >>>
|
25483805
|
Embryonic kidney cells [Exosomes] More >>>
|
25483805
|
Embryonic kidney cells [Exosomes] More >>>
|
29955024
|
Embryonic kidney cells [Exosomes] More >>>
|
29955024
|
Embryonic kidney cells [Exosomes] More >>>
|
29955024
|
Endothelial cells [Microparticles] More >>>
|
18563738
|
Endothelial cells [Microparticles] More >>>
|
18563738
|
Endothelial cells [Microparticles] More >>>
|
18563738
|
Endothelial cells [Exosomes/Extracellular vesicles] More >>>
|
24009886
|
Epithelial cells [Exosomes] More >>>
|
25776846
|
Epithelial cells [Exosomes] More >>>
|
25776846
|
Glioblastoma cells [Microvesicles] More >>>
|
19011622
|
Glioblastoma cells [Extracellular vesicles] More >>>
|
27770278
|
Glioblastoma cells [Extracellular vesicles] More >>>
|
27770278
|
Glioblastoma cells [Extracellular vesicles] More >>>
|
27770278
|
Glioblastoma cells [Extracellular vesicles] More >>>
|
27770278
|
Glioblastoma cells [Extracellular vesicles] More >>>
|
27770278
|
Glioblastoma cells [Extracellular vesicles] More >>>
|
27770278
|
Kidney cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Exosomes] More >>>
|
24939845
|
Leukemia cells [Exosomes] More >>>
|
24939845
|
Leukemia cells [Exosomes] More >>>
|
24939845
|
Leukemia cells [Exosomes] More >>>
|
24939845
|
Malignant pleural effusions [Exosomes] More >>>
|
21601258
|
Malignant pleural effusions [Exosomes/Microvesicles/Ectosomes/Microparticles] More >>>
|
23585444
|
Melanoma cells [Exosomes] More >>>
|
22635005
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Mesenchymal stem cells [Microvesicles] More >>>
|
22148876
|
Mesenchymal stem cells [Microvesicles] More >>>
|
22148876
|
Mesenchymal stem cells [Microvesicles] More >>>
|
22148876
|
Myeloid leukemia cells [Exosomes] More >>>
|
29955024
|
Myeloid leukemia cells [Exosomes] More >>>
|
29955024
|
Myeloid leukemia cells [Exosomes] More >>>
|
29955024
|
Neonatal myoblast cells [Microvesicles/Nanovesicles] More >>>
|
23000592
|
Neonatal myoblast cells [Microvesicles/Nanovesicles] More >>>
|
23000592
|
Neuroblastoma cells [Exosomes] More >>>
|
25053844
|
Osteosarcoma cells [Matrix vesicles] More >>>
|
21515422
|
Ovarian cancer cells [Exosomes] More >>>
|
23333927
|
Ovarian cancer cells [Exosomes] More >>>
|
23333927
|
Ovarian cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Ovarian cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Pancreatic adenocarcinoma cells [Exosomes] More >>>
|
24218614
|
Pancreatic adenocarcinoma cells [Exosomes] More >>>
|
24218614
|
Pancreatic adenocarcinoma cells [Exosomes] More >>>
|
24218614
|
Plasma [Microparticles] More >>>
|
22669077
|
Plasma [Microparticles] More >>>
|
23056467
|
Platelets [Microparticles] More >>>
|
16212402
|
Prostate cancer cells [Exosomes] More >>>
|
22030351
|
Prostate cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Prostate cancer cells [Extracellular vesicles] More >>>
|
28881726
|
Prostate cancer cells [Extracellular vesicles] More >>>
|
28881726
|
Prostate cancer cells [Exosomes] More >>>
|
24391718
|
Prostate cancer cells [Exosomes] More >>>
|
24391718
|
Prostate cancer cells [Exosomes] More >>>
|
24347249
|
Prostate cancer cells [Exosomes] More >>>
|
24347249
|
Prostate epithelial cells [Exosomes] More >>>
|
24391718
|
Prostate epithelial cells [Exosomes] More >>>
|
24391718
|
Prostate epithelial cells [Exosomes] More >>>
|
24391718
|
Prostate epithelial cells [Exosomes] More >>>
|
24391718
|
Prostate epithelial cells [Exosomes] More >>>
|
24391718
|
Prostate epithelial cells [Exosomes] More >>>
|
24391718
|
Retinal pigment epithelial cells [Exosomes] More >>>
|
24400796
|
Retinal pigment epithelial cells [Exosomes] More >>>
|
24400796
|
Saliva [Exosomes] More >>>
|
21212511
|
Saliva [Exosomes] More >>>
|
21212511
|
Synovial fluid [Extracellular vesicles] More >>>
|
29963299
|
T cells [Apoptotic bodies] More >>>
|
28811610
|
T cells [Microvesicles] More >>>
|
28811610
|
T cells [Apoptotic bodies] More >>>
|
28811610
|
T cells [Microvesicles] More >>>
|
28811610
|
T cells [Apoptotic bodies] More >>>
|
28811610
|
T cells [Exosomes] More >>>
|
24939845
|
T cells [Exosomes] More >>>
|
24939845
|
Thymus [Exosomes] More >>>
|
23844026
|
Trophoblast cells [Exosomes] More >>>
|
21276792
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Urine [Exosomes] More >>>
|
17700640
|
Urine [Exosomes/Membrane vesicles] More >>>
|
22106071
|
Urine [Extracellular vesicles] More >>>
|
29988836
|
Urine [Extracellular vesicles] More >>>
|
25329303
|
Urine [Extracellular vesicles] More >>>
|
25329303
|
Urothelial cells [Extracellular vesicles] More >>>
|
29207636
|
Urothelial cells [Extracellular vesicles] More >>>
|
29207636
|
Experiment description of studies that identified HSPA4 in extracellular vesicles |
1
|
Experiment ID | 1099 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24513287
|
Organism | Mus musculus |
Experiment description | Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. |
Authors | Sano S, Izumi Y, Yamaguchi T, Yamazaki T, Tanaka M, Shiota M, Osada-Oka M, Nakamura Y, Wei M, Wanibuchi H, Iwao H, Yoshiyama M. |
Journal name |
Biochem Biophys Res Commun
|
Publication year | 2014 |
Sample | adipocytes |
Sample name | 3T3-L1- Normoxic conditions |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV140281: EV-METRIC:0%, 22%
|
|
|
2
|
Experiment ID | 1100 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24513287
|
Organism | Mus musculus |
Experiment description | Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. |
Authors | Sano S, Izumi Y, Yamaguchi T, Yamazaki T, Tanaka M, Shiota M, Osada-Oka M, Nakamura Y, Wei M, Wanibuchi H, Iwao H, Yoshiyama M. |
Journal name |
Biochem Biophys Res Commun
|
Publication year | 2014 |
Sample | adipocytes |
Sample name | 3T3-L1- Hypoxic conditions |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV140281: EV-METRIC:0%, 22%
|
|
|
3
|
Experiment ID | 660 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
29964051
|
Organism | Homo sapiens |
Experiment description | Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway |
Authors | Zhang W, Bai X, Zhao B, Li Y, Zhang Y, Li Z, Wang X, Luo L, Han F, Zhang J, Han S, Cai W, Su L, Tao K, Shi J, Hu D. |
Journal name |
Exp Cell Res
|
Publication year | 2018 |
Sample | Adipose tissue-derived stem cells |
Sample name | Normal ADSC's |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Flow cytometry |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 58 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
17700640
|
Organism | Homo sapiens |
Experiment description | CD24 is a marker of exosomes secreted into urine and amniotic fluid. |
Authors | Keller S, Rupp C, Stoeck A, Runz S, Fogel M, Lugert S, Hager HD, Abdel-Bakky MS, Gutwein P, Altevogt P |
Journal name |
KI
|
Publication year | 2007 |
Sample | Amniotic fluid |
Sample name | Amniotic fluid |
Isolation/purification methods | Differential centrifugation Sucrose density gradient |
Flotation density | 1.08-1.14 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 1258 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24400796
|
Organism | Homo sapiens |
Experiment description | Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. |
Authors | Kang GY, Bang JY, Choi AJ, Yoon J, Lee WC, Choi S, Yoon S, Kim HC, Baek JH, Park HS, Lim HJ, Chung H. |
Journal name |
J Proteome Res.
|
Publication year | 2014 |
Sample | Aqueous humor |
Sample name | Age-related macular degeneration patients |
Isolation/purification methods | ExoQuick |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140174: EV-METRIC:13%, 13%
|
|
|
6
|
Experiment ID | 108 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
21601258
|
Organism | Homo sapiens |
Experiment description | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. |
Authors | Rupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P. |
Journal name |
GO
|
Publication year | 2011 |
Sample | Ascites |
Sample name | Malignant ascites - ovarian cancer |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (EpCAM, CD24) |
Flotation density | 1.04-1.15 g/mL |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting Immunoelectron microscopy |
EV-TRACK |
EV110020: EV-METRIC:13%, 63%, 50%
|
|
|
7
|
Experiment ID | 110 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
21601258
|
Organism | Homo sapiens |
Experiment description | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. |
Authors | Rupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P. |
Journal name |
GO
|
Publication year | 2011 |
Sample | Ascites |
Sample name | Ascites - liver cirrhosis |
Isolation/purification methods | Differential centrifugation Sucrose density gradient |
Flotation density | 1.04-1.10 g/mL |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting Immunoelectron microscopy |
EV-TRACK |
EV110020: EV-METRIC:13%, 63%, 50%
|
|
|
8
|
Experiment ID | 1059 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373 - EVs 1 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 1060 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373 - EVs 2 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
10
|
Experiment ID | 1061 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373 - EVs 3 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
11
|
Experiment ID | 1062 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373vIII - EVs 1 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
12
|
Experiment ID | 1063 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373vIII - EVs 2 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
13
|
Experiment ID | 1064 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373vIII - EVs 3 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
14
|
Experiment ID | 79 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
15
|
Experiment ID | 80 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
16
|
Experiment ID | 81 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
17
|
Experiment ID | 308 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [Q-TOF]
|
PubMed ID |
16342139
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization |
Authors | Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet JM, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L |
Journal name |
Proteomics
|
Publication year | 2006 |
Sample | B cells |
Sample name | B cells - Chronic B cell lymphoid patient |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [QTOF] |
EV-TRACK |
-
|
|
|
18
|
Experiment ID | 534 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles/Oncosomes/Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23818640
|
Organism | Homo sapiens |
Experiment description | Modulation of B-cell exosome proteins by gamma herpesvirus infection. |
Authors | Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. |
Journal name |
Proc Natl Acad Sci U S A
|
Publication year | 2013 |
Sample | B cells |
Sample name | EBV- and KSHV-infected B cells (JSC-1, BC1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130064: EV-METRIC:25%
|
|
|
19
|
Experiment ID | 535 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles/Oncosomes/Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23818640
|
Organism | Homo sapiens |
Experiment description | Modulation of B-cell exosome proteins by gamma herpesvirus infection. |
Authors | Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. |
Journal name |
Proc Natl Acad Sci U S A
|
Publication year | 2013 |
Sample | B cells |
Sample name | EBV-infected B cells (#1, HLJ, IM9, CP) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130064: EV-METRIC:25%
|
|
|
20
|
Experiment ID | 536 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles/Oncosomes/Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23818640
|
Organism | Homo sapiens |
Experiment description | Modulation of B-cell exosome proteins by gamma herpesvirus infection. |
Authors | Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. |
Journal name |
Proc Natl Acad Sci U S A
|
Publication year | 2013 |
Sample | B cells |
Sample name | KSHV-infected B cell (JC, BC3, BCP1, BCBL1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130064: EV-METRIC:25%
|
|
|
21
|
Experiment ID | 537 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles/Oncosomes/Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23818640
|
Organism | Homo sapiens |
Experiment description | Modulation of B-cell exosome proteins by gamma herpesvirus infection. |
Authors | Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. |
Journal name |
Proc Natl Acad Sci U S A
|
Publication year | 2013 |
Sample | B cells |
Sample name | Normal B cells (BJAB) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130064: EV-METRIC:25%
|
|
|
22
|
Experiment ID | 905 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29207636
|
Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
|
Publication year | 2017 |
Sample | Bladder cancer cells |
Sample name | TCCSUP |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
|
|
|
23
|
Experiment ID | 930 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29207636
|
Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
|
Publication year | 2017 |
Sample | Bladder cancer cells |
Sample name | TCCSUP |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
|
|
|
24
|
Experiment ID | 580 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Brain cancer cells |
Sample name | T-47D |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
25
|
Experiment ID | 581 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Brain cancer cells |
Sample name | SF268 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
26
|
Experiment ID | 584 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Brain cancer cells |
Sample name | SNB-19 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
27
|
Experiment ID | 575 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | BT549 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
28
|
Experiment ID | 577 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | MCF7 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
29
|
Experiment ID | 578 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
30
|
Experiment ID | 886 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting Mass spectrometry
|
PubMed ID |
25102470
|
Organism | Homo sapiens |
Experiment description | Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro |
Authors | Smyth TJ, Redzic JS, Graner MW, Anchordoquy TJ. |
Journal name |
Biochim Biophys Acta
|
Publication year | 2014 |
Sample | Breast cancer cells |
Sample name | MCF-7 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.10-1.20 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140013: EV-METRIC:56%
|
|
|
31
|
Experiment ID | 574 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ-Orbitrap Elite, Q-Exactive]
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components |
Authors | Van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
MCP
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Breast milk - normal |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
32
|
Experiment ID | 951 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
33
|
Experiment ID | 956 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D7 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
34
|
Experiment ID | 957 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - pooled |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
35
|
Experiment ID | 1207 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 1 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
36
|
Experiment ID | 1208 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 2 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
37
|
Experiment ID | 1209 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 3 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
38
|
Experiment ID | 1210 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 4 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
39
|
Experiment ID | 1211 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 5 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
40
|
Experiment ID | 1206 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | BEAS-2B untreated |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
41
|
Experiment ID | 1286 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
20880880
|
Organism | Homo sapiens |
Experiment description | Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis. |
Authors | Qazi KR, Torregrosa Paredes P, Dahlberg B, Grunewald J, Eklund A, Gabrielsson S |
Journal name |
Thorax.
|
Publication year | 2010 |
Sample | Bronchoalveolar lavage fluid |
Sample name | BALF - Healthy |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09.1.19.g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV100006: EV-METRIC:56%
|
|
|
42
|
Experiment ID | 1287 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
20880880
|
Organism | Homo sapiens |
Experiment description | Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis. |
Authors | Qazi KR, Torregrosa Paredes P, Dahlberg B, Grunewald J, Eklund A, Gabrielsson S |
Journal name |
Thorax.
|
Publication year | 2010 |
Sample | Bronchoalveolar lavage fluid |
Sample name | BALF - sarcoidosis |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09.1.19.g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV100006: EV-METRIC:56%
|
|
|
43
|
Experiment ID | 899 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
26100252
|
Organism | Homo sapiens |
Experiment description | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts |
Authors | Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. |
Journal name |
Blood
|
Publication year | 2015 |
Sample | Chronic lymphocytic leukemia cells |
Sample name | CLL cells - Rep 1 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.17 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150015: EV-METRIC:22%, 44%
|
|
|
44
|
Experiment ID | 901 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
26100252
|
Organism | Homo sapiens |
Experiment description | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts |
Authors | Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. |
Journal name |
Blood
|
Publication year | 2015 |
Sample | Chronic lymphocytic leukemia cells |
Sample name | JVM-3 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.17 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150015: EV-METRIC:22%, 44%
|
|
|
45
|
Experiment ID | 902 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
26100252
|
Organism | Homo sapiens |
Experiment description | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts |
Authors | Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. |
Journal name |
Blood
|
Publication year | 2015 |
Sample | Chronic lymphocytic leukemia cells |
Sample name | MEC-1 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.17 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry FACS Western blotting |
EV-TRACK |
EV150015: EV-METRIC:22%, 44%
|
|
|
46
|
Experiment ID | 20 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
17956143
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human colorectal cancer cells. |
Authors | Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS |
Journal name |
JPR
|
Publication year | 2007 |
Sample | Colorectal cancer cells |
Sample name | HT29 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Diafiltration |
Flotation density | 1.16 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] Western blotting |
EV-TRACK |
-
|
|
|
47
|
Experiment ID | 303 |
Identified molecule | mrna
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray [Illumina]
|
PubMed ID |
19930720
|
Organism | Homo sapiens |
Experiment description | Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells |
Authors | Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS |
Journal name |
BMC Genomics
|
Publication year | 2009 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | Differential centrifugation Ultrafiltration OptiPrep density gradient |
Flotation density | 1.09 g/mL |
Molecules identified in the study | Protein mRNA |
Methods used in the study | Western blotting RT-PCR Microarray [Illumina] |
EV-TRACK |
-
|
|
|
48
|
Experiment ID | 486 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | A33 affinity purified exosomes-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
49
|
Experiment ID | 487 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | EpCAM affinity purified exosomes-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
50
|
Experiment ID | 488 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | Shed vesicles-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
51
|
Experiment ID | 517 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23585443
|
Organism | Homo sapiens |
Experiment description | Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. |
Authors | Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130010: EV-METRIC:44%
|
|
|
52
|
Experiment ID | 518 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23585443
|
Organism | Homo sapiens |
Experiment description | Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. |
Authors | Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Colorectal cancer cells |
Sample name | SW620 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130010: EV-METRIC:44%
|
|
|
53
|
Experiment ID | 549 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles/Ectosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24009881
|
Organism | Homo sapiens |
Experiment description | Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. |
Authors | Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. |
Journal name |
J Extracell Vesicles
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120013: EV-METRIC:50%
|
|
|
54
|
Experiment ID | 550 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles/Ectosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24009881
|
Organism | Homo sapiens |
Experiment description | Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. |
Authors | Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. |
Journal name |
J Extracell Vesicles
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | SW620 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120013: EV-METRIC:50%
|
|
|
55
|
Experiment ID | 591 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Colorectal cancer cells |
Sample name | HT29 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
56
|
Experiment ID | 592 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Colorectal cancer cells |
Sample name | KM12 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
57
|
Experiment ID | 593 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Colorectal cancer cells |
Sample name | SW620 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
58
|
Experiment ID | 696 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | LIM1215- insulin induced |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
59
|
Experiment ID | 697 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | LIM1215- non-induced |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
60
|
Experiment ID | 1049 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics.
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | LIM1215 - NI |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
61
|
Experiment ID | 1050 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics.
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | lim1215 - II |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
62
|
Experiment ID | 562 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F3 10K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
63
|
Experiment ID | 563 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F5 10K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.14 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
64
|
Experiment ID | 564 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F3 100K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
65
|
Experiment ID | 565 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [LTQ ORBITRAP]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F5 100K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.14 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ ORBITRAP] |
EV-TRACK |
-
|
|
|
66
|
Experiment ID | 568 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ FUSION]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (CD9 PD) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Immunobeads (CD9 PD) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ FUSION] |
EV-TRACK |
-
|
|
|
67
|
Experiment ID | 925 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25483805
|
Organism | Homo sapiens |
Experiment description | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties |
Authors | Vyas N, Walvekar A, Tate D, Lakshmanan V, Bansal D, Lo Cicero A, Raposo G, Palakodeti D, Dhawan J. |
Journal name |
Sci Rep
|
Publication year | 2014 |
Sample | Embryonic kidney cells |
Sample name | HEK293T - P150 - Fraction 1.12 g/mL |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.12 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140018: EV-METRIC:56%, 56%
|
|
|
68
|
Experiment ID | 927 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25483805
|
Organism | Homo sapiens |
Experiment description | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties |
Authors | Vyas N, Walvekar A, Tate D, Lakshmanan V, Bansal D, Lo Cicero A, Raposo G, Palakodeti D, Dhawan J. |
Journal name |
Sci Rep
|
Publication year | 2014 |
Sample | Embryonic kidney cells |
Sample name | HEK293T - P450 - Fraction 1.12 g/mL |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.12 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140018: EV-METRIC:56%, 56%
|
|
|
69
|
Experiment ID | 876 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
29955024
|
Organism | Homo sapiens |
Experiment description | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells |
Authors | Mohamed NNI, Okada T, Kajimoto T, Nakamura SI. |
Journal name |
Kobe J Med Sci
|
Publication year | 2018 |
Sample | Embryonic kidney cells |
Sample name | HEK293T - control siRNA transfected |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
70
|
Experiment ID | 877 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
29955024
|
Organism | Homo sapiens |
Experiment description | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells |
Authors | Mohamed NNI, Okada T, Kajimoto T, Nakamura SI. |
Journal name |
Kobe J Med Sci
|
Publication year | 2018 |
Sample | Embryonic kidney cells |
Sample name | HEK293T - SphK1 siRNA transfected |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
71
|
Experiment ID | 878 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
29955024
|
Organism | Homo sapiens |
Experiment description | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells |
Authors | Mohamed NNI, Okada T, Kajimoto T, Nakamura SI. |
Journal name |
Kobe J Med Sci
|
Publication year | 2018 |
Sample | Embryonic kidney cells |
Sample name | HEK293T - SphK2 siRNA transfected |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
72
|
Experiment ID | 385 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
18563738
|
Organism | Homo sapiens |
Experiment description | Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. |
Authors | Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. |
Journal name |
Proteomics
|
Publication year | 2008 |
Sample | Endothelial cells |
Sample name | Endothelial cells (HUVEC) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
73
|
Experiment ID | 386 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
18563738
|
Organism | Homo sapiens |
Experiment description | Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. |
Authors | Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. |
Journal name |
Proteomics
|
Publication year | 2008 |
Sample | Endothelial cells |
Sample name | Treated by PAI-1-Endothelial cell (HUVEC) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
74
|
Experiment ID | 387 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
18563738
|
Organism | Homo sapiens |
Experiment description | Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. |
Authors | Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. |
Journal name |
Proteomics
|
Publication year | 2008 |
Sample | Endothelial cells |
Sample name | Treated by TNF-alpha-Endothelial cells (HUVEC) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
75
|
Experiment ID | 551 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
24009886
|
Organism | Homo sapiens |
Experiment description | Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. |
Authors | de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. |
Journal name |
J Extracell Vesicles
|
Publication year | 2012 |
Sample | Endothelial cells |
Sample name | Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120004: EV-METRIC:67%
|
|
|
76
|
Experiment ID | 861 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25776846
|
Organism | Homo sapiens |
Experiment description | Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens |
Authors | Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, Ekwall O. |
Journal name |
Immunol Cell Biol
|
Publication year | 2015 |
Sample | Epithelial cells |
Sample name | Thymic tissue - culture 1 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150045: EV-METRIC:25%
|
|
|
77
|
Experiment ID | 862 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25776846
|
Organism | Homo sapiens |
Experiment description | Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens |
Authors | Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, Ekwall O. |
Journal name |
Immunol Cell Biol
|
Publication year | 2015 |
Sample | Epithelial cells |
Sample name | Thymic tissue - culture 2 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150045: EV-METRIC:25%
|
|
|
78
|
Experiment ID | 203 |
Identified molecule | mrna
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray
|
PubMed ID |
19011622
|
Organism | Homo sapiens |
Experiment description | Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers |
Authors | Skog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO |
Journal name |
Nat Cell Biol
|
Publication year | 2008 |
Sample | Glioblastoma cells |
Sample name | Glioblastoma cells |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein miRNA mRNA |
Methods used in the study | RT-PCR Antibody array Microarray |
EV-TRACK |
-
|
|
|
79
|
Experiment ID | 1039 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | A172 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
80
|
Experiment ID | 1040 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | LN229 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
81
|
Experiment ID | 1041 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | U87MG |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
82
|
Experiment ID | 1042 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | U251 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
83
|
Experiment ID | 1043 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | T98G |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
84
|
Experiment ID | 1044 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | CCF-STTG1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
85
|
Experiment ID | 595 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Kidney cancer cells |
Sample name | A498 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
86
|
Experiment ID | 604 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | K562 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
87
|
Experiment ID | 605 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | MOLT-4 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
88
|
Experiment ID | 1248 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry Western blotting
|
PubMed ID |
24939845
|
Organism | Homo sapiens |
Experiment description | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. |
Authors | Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F. |
Journal name |
J Biol Chem.
|
Publication year | 2014 |
Sample | Leukemia cells |
Sample name | CEM - uninfected |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140028: EV-METRIC:33%
|
|
|
89
|
Experiment ID | 1249 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24939845
|
Organism | Homo sapiens |
Experiment description | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. |
Authors | Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F. |
Journal name |
J Biol Chem.
|
Publication year | 2014 |
Sample | Leukemia cells |
Sample name | C81 - HTLV-1 infected |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140028: EV-METRIC:33%
|
|
|
90
|
Experiment ID | 1250 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24939845
|
Organism | Homo sapiens |
Experiment description | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. |
Authors | Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F. |
Journal name |
J Biol Chem.
|
Publication year | 2014 |
Sample | Leukemia cells |
Sample name | MT2 - HTLV-1 infected |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140028: EV-METRIC:33%
|
|
|
91
|
Experiment ID | 1251 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24939845
|
Organism | Homo sapiens |
Experiment description | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. |
Authors | Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F. |
Journal name |
J Biol Chem.
|
Publication year | 2014 |
Sample | Leukemia cells |
Sample name | ED-40515 -HTLV-1 infected |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140028: EV-METRIC:33%
|
|
|
92
|
Experiment ID | 109 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
21601258
|
Organism | Homo sapiens |
Experiment description | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. |
Authors | Rupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P. |
Journal name |
GO
|
Publication year | 2011 |
Sample | Malignant pleural effusions |
Sample name | Pleural effusions - breast cancer |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (EpCAM) |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting |
EV-TRACK |
EV110020: EV-METRIC:13%, 63%, 50%
|
|
|
93
|
Experiment ID | 519 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles/Ectosomes/Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23585444
|
Organism | Homo sapiens |
Experiment description | Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. |
Authors | Park JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, Kim KP. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Malignant pleural effusions |
Sample name | Non-small cell lung cancer patient-Lung cancer pleural effusion |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130049: EV-METRIC:38%
|
|
|
94
|
Experiment ID | 453 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
22635005
|
Organism | Homo sapiens |
Experiment description | Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. |
Authors | Peinado H, Alecković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D. |
Journal name |
Nat Med
|
Publication year | 2012 |
Sample | Melanoma cells |
Sample name | B16-F10, SK-MEL-202, SK-MEL035, SK-MEL-265 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120019: EV-METRIC:44%, 44%, 44%
|
|
|
95
|
Experiment ID | 620 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | MDA-MB-435 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
96
|
Experiment ID | 244 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry[Q-TOF]
|
PubMed ID |
22148876
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human mesenchymal stem cells |
Authors | Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW |
Journal name |
J Proteome Res
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | Mesenchymal stem cells - Rep 1 |
Isolation/purification methods | Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry[QTOF] |
EV-TRACK |
-
|
|
|
97
|
Experiment ID | 310 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry[Q-TOF]
|
PubMed ID |
22148876
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human mesenchymal stem cells |
Authors | Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW |
Journal name |
J Proteome Res
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | Mesenchymal stem cells - Rep 2 |
Isolation/purification methods | Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry[QTOF] |
EV-TRACK |
-
|
|
|
98
|
Experiment ID | 311 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry[Q-TOF]
|
PubMed ID |
22148876
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human mesenchymal stem cells |
Authors | Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW |
Journal name |
J Proteome Res
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | Mesenchymal stem cells - Rep 3 |
Isolation/purification methods | Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry[QTOF] |
EV-TRACK |
-
|
|
|
99
|
Experiment ID | 883 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
29955024
|
Organism | Homo sapiens |
Experiment description | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells |
Authors | Mohamed NNI, Okada T, Kajimoto T, Nakamura SI. |
Journal name |
Kobe J Med Sci
|
Publication year | 2018 |
Sample | Myeloid leukemia cells |
Sample name | K562 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
100
|
Experiment ID | 884 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
29955024
|
Organism | Homo sapiens |
Experiment description | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells |
Authors | Mohamed NNI, Okada T, Kajimoto T, Nakamura SI. |
Journal name |
Kobe J Med Sci
|
Publication year | 2018 |
Sample | Myeloid leukemia cells |
Sample name | K562 - DMS treated |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
101
|
Experiment ID | 885 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
29955024
|
Organism | Homo sapiens |
Experiment description | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells |
Authors | Mohamed NNI, Okada T, Kajimoto T, Nakamura SI. |
Journal name |
Kobe J Med Sci
|
Publication year | 2018 |
Sample | Myeloid leukemia cells |
Sample name | K562 - HACPT treated |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
102
|
Experiment ID | 467 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23000592
|
Organism | Homo sapiens |
Experiment description | In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. |
Authors | Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. |
Journal name |
J Proteomics
|
Publication year | 2012 |
Sample | Neonatal myoblast cells |
Sample name | Patient of developmental heart defect_exosome-Neonatal myoblast cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
103
|
Experiment ID | 468 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23000592
|
Organism | Homo sapiens |
Experiment description | In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. |
Authors | Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. |
Journal name |
J Proteomics
|
Publication year | 2012 |
Sample | Neonatal myoblast cells |
Sample name | Patient of developmental heart defect_microparticle-Neonatal myoblast cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
104
|
Experiment ID | 903 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25053844
|
Organism | Homo sapiens |
Experiment description | Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons |
Authors | Goldie BJ, Dun MD, Lin M, Smith ND, Verrills NM, Dayas CV, Cairns MJ. |
Journal name |
Nucleic Acids Res
|
Publication year | 2014 |
Sample | Neuroblastoma cells |
Sample name | SH-SY5Y |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140076: EV-METRIC:38%
|
|
|
105
|
Experiment ID | 428 |
Identified molecule | protein
|
Extracellular vesicle type | Matrix vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
21515422
|
Organism | Homo sapiens |
Experiment description | Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells. |
Authors | Thouverey C, Malinowska A, Balcerzak M, Strzelecka-Kiliszek A, Buchet R, Dadlez M, Pikula S. |
Journal name |
J Proteomics
|
Publication year | 2011 |
Sample | Osteosarcoma cells |
Sample name | Normal-Osteosarcoma cell (Saos-2 ATCC HTB-85) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
106
|
Experiment ID | 492 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23333927
|
Organism | Homo sapiens |
Experiment description | Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors | Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year | 2013 |
Sample | Ovarian cancer cells |
Sample name | IGROV1 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130002: EV-METRIC:67%, 56%
|
|
|
107
|
Experiment ID | 493 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23333927
|
Organism | Homo sapiens |
Experiment description | Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors | Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year | 2013 |
Sample | Ovarian cancer cells |
Sample name | OVCAR-3 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130002: EV-METRIC:67%, 56%
|
|
|
108
|
Experiment ID | 629 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Ovarian cancer cells |
Sample name | OVCAR-5 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
109
|
Experiment ID | 632 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Ovarian cancer cells |
Sample name | NCI-ADR-RES |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
110
|
Experiment ID | 992 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
111
|
Experiment ID | 993 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR433 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
112
|
Experiment ID | 994 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
113
|
Experiment ID | 995 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | SKOV3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
114
|
Experiment ID | 1267 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24218614
|
Organism | Homo sapiens |
Experiment description | Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. |
Authors | Shin SJ, Smith JA, Rezniczek GA, Pan S, Chen R, Brentnall TA, Wiche G, Kelly KA. |
Journal name |
Proc Natl Acad Sci U S A.
|
Publication year | 2013 |
Sample | Pancreatic adenocarcinoma cells |
Sample name | Bxpc 3 Cells |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV130114: EV-METRIC:33%, 0%, 17%
|
|
|
115
|
Experiment ID | 1268 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24218614
|
Organism | Homo sapiens |
Experiment description | Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. |
Authors | Shin SJ, Smith JA, Rezniczek GA, Pan S, Chen R, Brentnall TA, Wiche G, Kelly KA. |
Journal name |
Proc Natl Acad Sci U S A.
|
Publication year | 2013 |
Sample | Pancreatic adenocarcinoma cells |
Sample name | Panc-1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV130114: EV-METRIC:33%, 0%, 17%
|
|
|
116
|
Experiment ID | 1269 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24218614
|
Organism | Homo sapiens |
Experiment description | Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. |
Authors | Shin SJ, Smith JA, Rezniczek GA, Pan S, Chen R, Brentnall TA, Wiche G, Kelly KA. |
Journal name |
Proc Natl Acad Sci U S A.
|
Publication year | 2013 |
Sample | Pancreatic adenocarcinoma cells |
Sample name | L3.6pl- wild type cells |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV130114: EV-METRIC:33%, 0%, 17%
|
|
|
117
|
Experiment ID | 454 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
22669077
|
Organism | Homo sapiens |
Experiment description | The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation. |
Authors | Bosman GJ, Lasonder E, Groenen-Döpp YA, Willekens FL, Werre JM. |
Journal name |
J Proteomics
|
Publication year | 2012 |
Sample | Plasma |
Sample name | Normal-Blood |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
118
|
Experiment ID | 473 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23056467
|
Organism | Homo sapiens |
Experiment description | Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy. |
Authors | Al Kaabi A, Traupe T, Stutz M, Buchs N, Heller M. |
Journal name |
PLoS One
|
Publication year | 2012 |
Sample | Plasma |
Sample name | Patients of external counterpulsation therapy-Blood |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
119
|
Experiment ID | 369 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
16212402
|
Organism | Homo sapiens |
Experiment description | The platelet microparticle proteome. |
Authors | Garcia BA, Smalley DM, Cho H, Shabanowitz J, Ley K, Hunt DF. |
Journal name |
J Proteome Res
|
Publication year | 2005 |
Sample | Platelets |
Sample name | Normal donors-Platelets |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
120
|
Experiment ID | 277 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [Q-TOF]
|
PubMed ID |
22030351
|
Organism | Homo sapiens |
Experiment description | Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways |
Authors | Inder KL, Zheng YZ, Davis MJ, Moon H, Loo D, Nguyen H, Clements JA, Parton RG, Foster LJ, Hill MM |
Journal name |
MCP
|
Publication year | 2011 |
Sample | Prostate cancer cells |
Sample name | PC-3 |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QTOF] |
EV-TRACK |
-
|
|
|
121
|
Experiment ID | 633 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Prostate cancer cells |
Sample name | DU145 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
122
|
Experiment ID | 853 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28881726
|
Organism | Homo sapiens |
Experiment description | Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer |
Authors | Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Prostate cancer cells |
Sample name | DUCaP - in CSS - Rep 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
|
|
|
123
|
Experiment ID | 855 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28881726
|
Organism | Homo sapiens |
Experiment description | Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer |
Authors | Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Prostate cancer cells |
Sample name | DUCaP - in CSS with DHT treatment - Rep 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
|
|
|
124
|
Experiment ID | 1113 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate cancer cells |
Sample name | VCaP- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
125
|
Experiment ID | 1115 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate cancer cells |
Sample name | VCaP- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
126
|
Experiment ID | 1122 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24347249
|
Organism | Homo sapiens |
Experiment description | Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. |
Authors | Ramteke A, Ting H, Agarwal C, Mateen S, Somasagara R, Hussain A, Graner M, Frederick B, Agarwal R, Deep G. |
Journal name |
Mol Carcinog
|
Publication year | 2015 |
Sample | Prostate cancer cells |
Sample name | LNCaP- Normoxic |
Isolation/purification methods | Differential centrifugation Ultracentrifugation ExoQuick |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV140124: EV-METRIC:43%, 25%
|
|
|
127
|
Experiment ID | 1123 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24347249
|
Organism | Homo sapiens |
Experiment description | Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. |
Authors | Ramteke A, Ting H, Agarwal C, Mateen S, Somasagara R, Hussain A, Graner M, Frederick B, Agarwal R, Deep G. |
Journal name |
Mol Carcinog
|
Publication year | 2015 |
Sample | Prostate cancer cells |
Sample name | LNCaP- Hypoxic |
Isolation/purification methods | Differential centrifugation Ultracentrifugation ExoQuick |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV140124: EV-METRIC:43%, 25%
|
|
|
128
|
Experiment ID | 1104 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate epithelial cells |
Sample name | PNT2C2- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
129
|
Experiment ID | 1105 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate epithelial cells |
Sample name | PNT2C2- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
130
|
Experiment ID | 1106 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate epithelial cells |
Sample name | PNT2C2- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
131
|
Experiment ID | 1107 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate epithelial cells |
Sample name | RWPE-1- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
132
|
Experiment ID | 1108 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate epithelial cells |
Sample name | RWPE-1- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
133
|
Experiment ID | 1109 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate epithelial cells |
Sample name | RWPE-1- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
134
|
Experiment ID | 1256 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry Western blotting
|
PubMed ID |
24400796
|
Organism | Homo sapiens |
Experiment description | Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. |
Authors | Kang GY, Bang JY, Choi AJ, Yoon J, Lee WC, Choi S, Yoon S, Kim HC, Baek JH, Park HS, Lim HJ, Chung H. |
Journal name |
J Proteome Res.
|
Publication year | 2014 |
Sample | Retinal pigment epithelial cells |
Sample name | ARPE-19 |
Isolation/purification methods | ExoQuick |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140174: EV-METRIC:13%, 13%
|
|
|
135
|
Experiment ID | 1257 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24400796
|
Organism | Homo sapiens |
Experiment description | Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. |
Authors | Kang GY, Bang JY, Choi AJ, Yoon J, Lee WC, Choi S, Yoon S, Kim HC, Baek JH, Park HS, Lim HJ, Chung H. |
Journal name |
J Proteome Res.
|
Publication year | 2014 |
Sample | Retinal pigment epithelial cells |
Sample name | ARPE-19 400 µM paraquat |
Isolation/purification methods | ExoQuick |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140174: EV-METRIC:13%, 13%
|
|
|
136
|
Experiment ID | 1155 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
21212511
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of two types of exosomes in human whole saliva. |
Authors | Ogawa Y, Miura Y, Harazono A, Kanai-Azuma M, Akimoto Y, Kawakami H, Yamaguchi T, Toda T, Endo T, Tsubuki M, Yanoshita R. |
Journal name |
Biol Pharm Bull
|
Publication year | 2011 |
Sample | Saliva |
Sample name | Exosome I |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Gel filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV110053: EV-METRIC:11%
|
|
|
137
|
Experiment ID | 1156 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
21212511
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of two types of exosomes in human whole saliva. |
Authors | Ogawa Y, Miura Y, Harazono A, Kanai-Azuma M, Akimoto Y, Kawakami H, Yamaguchi T, Toda T, Endo T, Tsubuki M, Yanoshita R. |
Journal name |
Biol Pharm Bull
|
Publication year | 2011 |
Sample | Saliva |
Sample name | Exosome II |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Gel filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV110053: EV-METRIC:11%
|
|
|
138
|
Experiment ID | 1066 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
|
PubMed ID |
29963299
|
Organism | Homo sapiens |
Experiment description | Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography. |
Authors | Foers AD, Chatfield S, Dagley LF, Scicluna BJ, Webb AI, Cheng L, Hill AF, Wicks IP, Pang KC. |
Journal name |
J Extracell Vesicles.
|
Publication year | 2018 |
Sample | Synovial fluid |
Sample name | synovial fluid - EVs untreated |
Isolation/purification methods | Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170028: EV-METRIC:77%
|
|
|
139
|
Experiment ID | 709 |
Identified molecule | protein
|
Extracellular vesicle type | Apoptotic bodies |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Control |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
140
|
Experiment ID | 711 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Activated |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
141
|
Experiment ID | 712 |
Identified molecule | protein
|
Extracellular vesicle type | Apoptotic bodies |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Activated |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
142
|
Experiment ID | 714 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Apoptotic |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
143
|
Experiment ID | 715 |
Identified molecule | protein
|
Extracellular vesicle type | Apoptotic bodies |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Apoptotic |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
144
|
Experiment ID | 1252 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24939845
|
Organism | Homo sapiens |
Experiment description | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. |
Authors | Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F. |
Journal name |
J Biol Chem.
|
Publication year | 2014 |
Sample | T cells |
Sample name | Jurkat T-cells |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV140028: EV-METRIC:33%
|
|
|
145
|
Experiment ID | 1253 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
24939845
|
Organism | Homo sapiens |
Experiment description | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. |
Authors | Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F. |
Journal name |
J Biol Chem.
|
Publication year | 2014 |
Sample | T cells |
Sample name | Jurkat T-cells with pACH |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV140028: EV-METRIC:33%
|
|
|
146
|
Experiment ID | 538 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23844026
|
Organism | Homo sapiens |
Experiment description | Characterization of human thymic exosomes. |
Authors | Skogberg G, Gudmundsdottir J, van der Post S, Sandström K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Thymus |
Sample name | Normal-Thymus |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130018: EV-METRIC:63%
|
|
|
147
|
Experiment ID | 121 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
21276792
|
Organism | Homo sapiens |
Experiment description | Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells. |
Authors | Atay S, Gercel-Taylor C, Kesimer M, Taylor DD. |
Journal name |
ECR
|
Publication year | 2011 |
Sample | Trophoblast cells |
Sample name | Sw71 |
Isolation/purification methods | Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.13-1.19 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [Orbitrap] Western blotting |
EV-TRACK |
EV110001: EV-METRIC:78%
|
|
|
148
|
Experiment ID | 680 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Preterm newborns- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
149
|
Experiment ID | 681 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Preterm newborns- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
150
|
Experiment ID | 682 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Preterm newborns- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
151
|
Experiment ID | 683 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Term infants- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
152
|
Experiment ID | 684 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Term infants- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
153
|
Experiment ID | 685 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Term infants- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
154
|
Experiment ID | 57 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Western blotting
|
PubMed ID |
17700640
|
Organism | Homo sapiens |
Experiment description | CD24 is a marker of exosomes secreted into urine and amniotic fluid. |
Authors | Keller S, Rupp C, Stoeck A, Runz S, Fogel M, Lugert S, Hager HD, Abdel-Bakky MS, Gutwein P, Altevogt P |
Journal name |
KI
|
Publication year | 2007 |
Sample | Urine |
Sample name | Urine - Normal |
Isolation/purification methods | Differential centrifugation Sucrose density gradient |
Flotation density | 1.05-1.15 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting FACS |
EV-TRACK |
-
|
|
|
155
|
Experiment ID | 437 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
22106071
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). |
Authors | Wang Z, Hill S, Luther JM, Hachey DL, Schey KL. |
Journal name |
Proteomics
|
Publication year | 2012 |
Sample | Urine |
Sample name | Normal donors-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120168: EV-METRIC:14%
|
|
|
156
|
Experiment ID | 751 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29988836
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine |
Authors | Oeyen E, Van Mol K, Baggerman G, Willems H, Boonen K, Rolfo C, Pauwels P, Jacobs A, Schildermans K, Cho WC, Mertens I. |
Journal name |
J Extracell Vesicles
|
Publication year | 2018 |
Sample | Urine |
Sample name | Urine - Fraction 8 and 9 pooled |
Isolation/purification methods | Filtration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170025: EV-METRIC:62%
|
|
|
157
|
Experiment ID | 1239 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
|
PubMed ID |
25329303
|
Organism | Homo sapiens |
Experiment description | Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. |
Authors | Ghosh A, Davey M, Chute IC, Griffiths SG, Lewis S, Chacko S, Barnett D, Crapoulet N, Fournier S, Joy A, Caissie MC, Ferguson AD, Daigle M, Meli MV, Lewis SM, Ouellette RJ. |
Journal name |
PLoS One.
|
Publication year | 2014 |
Sample | Urine |
Sample name | Pre-digital rectal exam |
Isolation/purification methods | Vn96 peptide precipitation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV140120: EV-METRIC:0%, 25%, 25%, 17%, 38%, 50%, 33%
|
|
|
158
|
Experiment ID | 1241 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
|
PubMed ID |
25329303
|
Organism | Homo sapiens |
Experiment description | Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. |
Authors | Ghosh A, Davey M, Chute IC, Griffiths SG, Lewis S, Chacko S, Barnett D, Crapoulet N, Fournier S, Joy A, Caissie MC, Ferguson AD, Daigle M, Meli MV, Lewis SM, Ouellette RJ. |
Journal name |
PLoS One.
|
Publication year | 2014 |
Sample | Urine |
Sample name | Post-digital rectal exam |
Isolation/purification methods | Vn96 peptide precipitation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV140120: EV-METRIC:0%, 25%, 25%, 17%, 38%, 50%, 33%
|
|
|
159
|
Experiment ID | 906 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29207636
|
Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
|
Publication year | 2017 |
Sample | Urothelial cells |
Sample name | SVHUC |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
|
|
|
160
|
Experiment ID | 931 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29207636
|
Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
|
Publication year | 2017 |
Sample | Urothelial cells |
Sample name | SVHUC |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
|
|
|