Gene description for CD63
Gene name	CD63 molecule
Gene symbol	CD63
Other names/aliases	AD1 HOP-26 ME491 MLA1 OMA81H Pltgp40 TSPAN30
Species	Homo sapiens
Experiment description of studies that identified CD63 in Saliva
1 Experiment ID 66 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 19199708    Organism Homo sapiens Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR Journal name JPR Publication year 2009 Sample Saliva Sample name Saliva Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting Immunoelectron microscopy EV-TRACK -
2 Experiment ID 122 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Immunoelectron microscopy PubMed ID 21235781    Organism Homo sapiens Experiment description Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Authors Läer C, Alikhani VS, Ekströ, Eldh M, Paredes PT, Bossios A, Sjöand M, Gabrielsson S, Löll J, Valadi H. Journal name JTM Publication year 2011 Sample Saliva Sample name Saliva - Normal Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study FACS Immunoelectron microscopy Western blotting EV-TRACK EV110029: EV-METRIC:14%, 29%, 14%
3 Experiment ID 1155 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 21212511    Organism Homo sapiens Experiment description Proteomic analysis of two types of exosomes in human whole saliva. Authors Ogawa Y, Miura Y, Harazono A, Kanai-Azuma M, Akimoto Y, Kawakami H, Yamaguchi T, Toda T, Endo T, Tsubuki M, Yanoshita R. Journal name Biol Pharm Bull Publication year 2011 Sample Saliva Sample name Exosome I Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Gel filtration Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK EV110053: EV-METRIC:11%
4 Experiment ID 1156 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 21212511    Organism Homo sapiens Experiment description Proteomic analysis of two types of exosomes in human whole saliva. Authors Ogawa Y, Miura Y, Harazono A, Kanai-Azuma M, Akimoto Y, Kawakami H, Yamaguchi T, Toda T, Endo T, Tsubuki M, Yanoshita R. Journal name Biol Pharm Bull Publication year 2011 Sample Saliva Sample name Exosome II Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Gel filtration Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK EV110053: EV-METRIC:11%
5 Experiment ID 2496 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 34368811    Organism Homo sapiens Experiment description Isolation and characterization of extracellular vesicles in saliva of children with asthma Authors Comfort N, Bloomquist TR, Shephard AP, Petty CR, Cunningham A, Hauptman M, Phipatanakul W, Baccarelli A. Journal name Extracell Vesicles Circ Nucl Acids Publication year 2021 Sample Saliva Sample name Cell-free saliva - children (4 -14 year old) with asthma Isolation/purification methods ExoQuick Kit Centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting ExoView immunocapture EV-TRACK -
6 Experiment ID 2772 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 33432243    Organism Homo sapiens Experiment description Exosome detection via the ultrafast-isolation system: EXODUS Authors Chen Y, Zhu Q, Cheng L, Wang Y, Li M, Yang Q, Hu L, Lou D, Li J, Dong X, Lee LP, Liu F. Journal name Nat Methods Publication year 2021 Sample Saliva Sample name Saliva Isolation/purification methods Filtration Exosome detection via ultrafast-isolation system (EXODUS) Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
7 Experiment ID 2773 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 33432243    Organism Homo sapiens Experiment description Exosome detection via the ultrafast-isolation system: EXODUS Authors Chen Y, Zhu Q, Cheng L, Wang Y, Li M, Yang Q, Hu L, Lou D, Li J, Dong X, Lee LP, Liu F. Journal name Nat Methods Publication year 2021 Sample Saliva Sample name Saliva Isolation/purification methods Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
8 Experiment ID 2774 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 33432243    Organism Homo sapiens Experiment description Exosome detection via the ultrafast-isolation system: EXODUS Authors Chen Y, Zhu Q, Cheng L, Wang Y, Li M, Yang Q, Hu L, Lou D, Li J, Dong X, Lee LP, Liu F. Journal name Nat Methods Publication year 2021 Sample Saliva Sample name Saliva Isolation/purification methods Filtration Polyethylene glycol-based precipitation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
9 Experiment ID 1394 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Flow cytometry PubMed ID 32939236    Organism Homo sapiens Experiment description Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Authors Conzelmann C, Groß R, Zou M, Krüger F, Görgens A, Gustafsson MO, El Andaloussi S, Münch J, Müller JA. Journal name J Extracell Vesicles Publication year 2020 Sample Saliva Sample name Saliva - pooled (CD9, CD63, and CD81-positive EVs) Isolation/purification methods Differential centrifugation Tangential flow filtration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Flow cytometry EV-TRACK -
10 Experiment ID 1395 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Flow cytometry PubMed ID 32939236    Organism Homo sapiens Experiment description Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Authors Conzelmann C, Groß R, Zou M, Krüger F, Görgens A, Gustafsson MO, El Andaloussi S, Münch J, Müller JA. Journal name J Extracell Vesicles Publication year 2020 Sample Saliva Sample name Saliva - pooled (CD9-positive EVs) Isolation/purification methods Differential centrifugation Tangential flow filtration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Flow cytometry EV-TRACK -
11 Experiment ID 1396 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Flow cytometry PubMed ID 32939236    Organism Homo sapiens Experiment description Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Authors Conzelmann C, Groß R, Zou M, Krüger F, Görgens A, Gustafsson MO, El Andaloussi S, Münch J, Müller JA. Journal name J Extracell Vesicles Publication year 2020 Sample Saliva Sample name Saliva - pooled (CD63-positive EVs) Isolation/purification methods Differential centrifugation Tangential flow filtration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Flow cytometry EV-TRACK -
12 Experiment ID 1397 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Flow cytometry PubMed ID 32939236    Organism Homo sapiens Experiment description Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Authors Conzelmann C, Groß R, Zou M, Krüger F, Görgens A, Gustafsson MO, El Andaloussi S, Münch J, Müller JA. Journal name J Extracell Vesicles Publication year 2020 Sample Saliva Sample name Saliva - pooled (CD81-positive EVs) Isolation/purification methods Differential centrifugation Tangential flow filtration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Flow cytometry EV-TRACK -
13 Experiment ID 2496 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method ExoView immunocapture PubMed ID 34368811    Organism Homo sapiens Experiment description Isolation and characterization of extracellular vesicles in saliva of children with asthma Authors Comfort N, Bloomquist TR, Shephard AP, Petty CR, Cunningham A, Hauptman M, Phipatanakul W, Baccarelli A. Journal name Extracell Vesicles Circ Nucl Acids Publication year 2021 Sample Saliva Sample name Cell-free saliva - children (4 -14 year old) with asthma Isolation/purification methods ExoQuick Kit Centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting ExoView immunocapture EV-TRACK -