Gene description for SDCBP
Gene name syndecan binding protein
Gene symbol SDCBP
Other names/aliases MDA-9
MDA9
SDCBP1
ST1
SYCL
TACIP18
Species Homo sapiens
 Experiment description of studies that identified SDCBP in Plasma

1
Experiment ID1703
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
Flow cytometry
PubMed ID 34108659   
OrganismHomo sapiens
Experiment descriptionQuantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
AuthorsKugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R.
Journal name Nat Cell Biol
Publication year2021
SamplePlasma
Sample nameHealthy
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Flow cytometry
EV-TRACK -

2
Experiment ID3341
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34887515   
OrganismHomo sapiens
Experiment descriptionSupermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
AuthorsZhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ.
Journal name Nat Cell Biol
Publication year2021
SamplePlasma
Sample nameColorectal cancer patients
Isolation/purification methodsDifferential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
ELISA
EV-TRACK -

3
Experiment ID3357
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34887515   
OrganismHomo sapiens
Experiment descriptionSupermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
AuthorsZhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ.
Journal name Nat Cell Biol
Publication year2021
SamplePlasma
Sample nameControl individuals
Isolation/purification methodsDifferential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

4
Experiment ID2379
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34355211   
OrganismHomo sapiens
Experiment descriptionA size-exclusion-based approach for purifying extracellular vesicles from human plasma
AuthorsVanderboom PM, Dasari S, Ruegsegger GN, Pataky MW, Lucien F, Heppelmann CJ, Lanza IR, Nair KS.
Journal name Cell Rep Methods
Publication year2021
SamplePlasma
Sample nameSEC Fraction 15
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

5
Experiment ID2380
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34355211   
OrganismHomo sapiens
Experiment descriptionA size-exclusion-based approach for purifying extracellular vesicles from human plasma
AuthorsVanderboom PM, Dasari S, Ruegsegger GN, Pataky MW, Lucien F, Heppelmann CJ, Lanza IR, Nair KS.
Journal name Cell Rep Methods
Publication year2021
SamplePlasma
Sample nameSEC Fraction 16
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

6
Experiment ID2381
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34355211   
OrganismHomo sapiens
Experiment descriptionA size-exclusion-based approach for purifying extracellular vesicles from human plasma
AuthorsVanderboom PM, Dasari S, Ruegsegger GN, Pataky MW, Lucien F, Heppelmann CJ, Lanza IR, Nair KS.
Journal name Cell Rep Methods
Publication year2021
SamplePlasma
Sample nameSEC Fraction 17
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

7
Experiment ID2382
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34355211   
OrganismHomo sapiens
Experiment descriptionA size-exclusion-based approach for purifying extracellular vesicles from human plasma
AuthorsVanderboom PM, Dasari S, Ruegsegger GN, Pataky MW, Lucien F, Heppelmann CJ, Lanza IR, Nair KS.
Journal name Cell Rep Methods
Publication year2021
SamplePlasma
Sample nameSEC Fraction 18
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

8
Experiment ID2383
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34355211   
OrganismHomo sapiens
Experiment descriptionA size-exclusion-based approach for purifying extracellular vesicles from human plasma
AuthorsVanderboom PM, Dasari S, Ruegsegger GN, Pataky MW, Lucien F, Heppelmann CJ, Lanza IR, Nair KS.
Journal name Cell Rep Methods
Publication year2021
SamplePlasma
Sample nameSEC Fraction 19
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

9
Experiment ID2384
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34355211   
OrganismHomo sapiens
Experiment descriptionA size-exclusion-based approach for purifying extracellular vesicles from human plasma
AuthorsVanderboom PM, Dasari S, Ruegsegger GN, Pataky MW, Lucien F, Heppelmann CJ, Lanza IR, Nair KS.
Journal name Cell Rep Methods
Publication year2021
SamplePlasma
Sample nameSEC Fraction 20
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

10
Experiment ID2385
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34355211   
OrganismHomo sapiens
Experiment descriptionA size-exclusion-based approach for purifying extracellular vesicles from human plasma
AuthorsVanderboom PM, Dasari S, Ruegsegger GN, Pataky MW, Lucien F, Heppelmann CJ, Lanza IR, Nair KS.
Journal name Cell Rep Methods
Publication year2021
SamplePlasma
Sample nameSEC Fraction 21
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

11
Experiment ID2398
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34355211   
OrganismHomo sapiens
Experiment descriptionA size-exclusion-based approach for purifying extracellular vesicles from human plasma
AuthorsVanderboom PM, Dasari S, Ruegsegger GN, Pataky MW, Lucien F, Heppelmann CJ, Lanza IR, Nair KS.
Journal name Cell Rep Methods
Publication year2021
SamplePlasma
Sample nameSEC Fraction 14-21
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

12
Experiment ID2399
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34355211   
OrganismHomo sapiens
Experiment descriptionA size-exclusion-based approach for purifying extracellular vesicles from human plasma
AuthorsVanderboom PM, Dasari S, Ruegsegger GN, Pataky MW, Lucien F, Heppelmann CJ, Lanza IR, Nair KS.
Journal name Cell Rep Methods
Publication year2021
SamplePlasma
Sample namePlasma
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

13
Experiment ID2400
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34355211   
OrganismHomo sapiens
Experiment descriptionA size-exclusion-based approach for purifying extracellular vesicles from human plasma
AuthorsVanderboom PM, Dasari S, Ruegsegger GN, Pataky MW, Lucien F, Heppelmann CJ, Lanza IR, Nair KS.
Journal name Cell Rep Methods
Publication year2021
SamplePlasma
Sample namePlasma
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

14
Experiment ID2431
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 29320704   
OrganismHomo sapiens
Experiment descriptionExtracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise
AuthorsWhitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA.
Journal name Cell Metab
Publication year2018
SamplePlasma
Sample namePlasma - 20K pellet
Isolation/purification methodsCentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

15
Experiment ID2432
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 29320704   
OrganismHomo sapiens
Experiment descriptionExtracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise
AuthorsWhitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA.
Journal name Cell Metab
Publication year2018
SamplePlasma
Sample namePlasma - 100K pellet
Isolation/purification methodsUltracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

16
Experiment ID2436
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 29320704   
OrganismHomo sapiens
Experiment descriptionExtracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise
AuthorsWhitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA.
Journal name Cell Metab
Publication year2018
SamplePlasma
Sample namePlasma
Isolation/purification methodsCentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

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