Browse results for vesicle type: Extracellular vesicles


 Vesiclepedia IDPubMed IDSpeciesExperiment descriptionSampleIdentificationsIsolation methodsVesicle typeMISEV
1 Vesiclepedia_1559 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells Protein Centrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
2 Vesiclepedia_1577 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
3 Vesiclepedia_2725 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
4 Vesiclepedia_3357 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Plasma Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Small extracellular vesicles Small EVs
5 Vesiclepedia_3103 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
6 Vesiclepedia_2316 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles T cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
7 Vesiclepedia_1628 34012515 Homo sapiens CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells Melanoma cells Protein
Lipid
Differential centrifugation
Centrifugal ultrafiltration
Size exclusion chromatography
Extracellular vesicles EVs
8 Vesiclepedia_2842 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
9 Vesiclepedia_1882 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
10 Vesiclepedia_3249 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
11 Vesiclepedia_1745 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
12 Vesiclepedia_3235 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
13 Vesiclepedia_1572 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
14 Vesiclepedia_1057 30035390 Mus musculus Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Mouse embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
15 Vesiclepedia_3377 36581870 Mus musculus Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Qiagen Exosome Purification Kit
Extracellular vesicles EVs
16 Vesiclepedia_1421 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
17 Vesiclepedia_463 22849433 Homo sapiens Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types. Embryonic kidney cells miRNA - Extracellular vesicles EVs
18 Vesiclepedia_3236 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
19 Vesiclepedia_2389 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
20 Vesiclepedia_996 24392111 Mus musculus Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk? Murine myoblast Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
21 Vesiclepedia_2901 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Pancreatic cancer cells Protein Filtration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
22 Vesiclepedia_1401 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells Protein Differential centrifugation
Tangential flow filtration
Ultracentrifugation
Extracellular vesicles Small EVs
23 Vesiclepedia_3534 31002856 Homo sapiens Detection of cell-free, exosomal and whole blood mitochondrial DNA copy number in plasma or whole blood of patients with serous epithelial ovarian cancer Plasma mtDNA Exosome Isolation Kit Extracellular Vesicles EVs
24 Vesiclepedia_3392 31827089 Lactobacillus crispatus Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues Lactobacillus crispatus Protein
Metabolite
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
25 Vesiclepedia_2382 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
26 Vesiclepedia_2067 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
27 Vesiclepedia_1579 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Fibroblasts ProteinmRNA Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
28 Vesiclepedia_2106 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
29 Vesiclepedia_1845 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
30 Vesiclepedia_1899 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
31 Vesiclepedia_2407 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Myoblasts Protein Filtration
Size exclusion chromatography
Extracellular vesicles Small EVs
32 Vesiclepedia_2682 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells Protein
Lipid
Metabolite
Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
33 Vesiclepedia_2014 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
34 Vesiclepedia_2504 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells Protein Size exclusion chromatography
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
35 Vesiclepedia_3242 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
36 Vesiclepedia_2822 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein
mRNA
miRNA
tRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
37 Vesiclepedia_2307 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Monocytes miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
38 Vesiclepedia_1032 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
exoEasy columns Extracellular vesicles EVs
39 Vesiclepedia_1395 32939236 Homo sapiens Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Saliva Protein
Lipid
Differential centrifugation
Tangential flow filtration
Size exclusion chromatography
Extracellular vesicles Small EVs
40 Vesiclepedia_2528 34315885 Mus musculus Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Kidney epithelial cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
41 Vesiclepedia_1715 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
42 Vesiclepedia_2803 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
43 Vesiclepedia_1736 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
44 Vesiclepedia_3499 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets Protein Differential centrifugation Extracellular vesicles EVs
45 Vesiclepedia_2131 36515353 Homo sapiens Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Plasma Metabolite
Protein
ExoQuick Kit
Centrifugation
Extracellular vesicles Small EVs
46 Vesiclepedia_3464 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells miRNA Filtration
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
47 Vesiclepedia_552 24009898 Mus musculus Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. Cardiomyocytes mRNA - Exosomes/Extracellular vesicles EVs
48 Vesiclepedia_2314 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles T cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
49 Vesiclepedia_2807 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
50 Vesiclepedia_2081 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
51 Vesiclepedia_2952 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes Protein Differential centrifugation Extracellular vesicles Large EVs
52 Vesiclepedia_1590 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Centrifugation Extracellular vesicles Large EVs
53 Vesiclepedia_1272 24058411 Homo sapiens Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
54 Vesiclepedia_950 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
55 Vesiclepedia_3240 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
56 Vesiclepedia_2867 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
57 Vesiclepedia_1762 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid Protein Differential centrifugation Extracellular vesicles Large EVs
58 Vesiclepedia_1750 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
59 Vesiclepedia_1396 32939236 Homo sapiens Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Saliva Protein
Lipid
Differential centrifugation
Tangential flow filtration
Size exclusion chromatography
Extracellular vesicles Small EVs
60 Vesiclepedia_933 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Bladder cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
61 Vesiclepedia_1212 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultracentrifugation Extracellular vesicles EVs
62 Vesiclepedia_1131 23954818 Homo sapiens Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Squamous carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
63 Vesiclepedia_1626 34012515 Homo sapiens CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells Melanoma cells Protein Differential centrifugation
Centrifugal ultrafiltration
Size exclusion chromatography
Extracellular vesicles EVs
64 Vesiclepedia_3298 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
65 Vesiclepedia_3253 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
66 Vesiclepedia_2431 29320704 Homo sapiens Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Plasma Protein Centrifugation Extracellular vesicles EVs
67 Vesiclepedia_2400 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
68 Vesiclepedia_2158 34140472 Ixodes scapularis Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Ixodes scapularis Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
69 Vesiclepedia_1911 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
70 Vesiclepedia_1310 - Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
71 Vesiclepedia_2894 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells Protein Filtration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
72 Vesiclepedia_1041 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Extracellular vesicles EVs
73 Vesiclepedia_2800 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
74 Vesiclepedia_2855 33579909 Homo sapiens Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
75 Vesiclepedia_2117 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient centrifugation
Small extracellular vesicles Small EVs
76 Vesiclepedia_3239 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
77 Vesiclepedia_3505 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets Protein Differential centrifugation Extracellular vesicles EVs
78 Vesiclepedia_2892 28928431 Mus musculus Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90 Lung cancer cells Protein Centrifugal ultrafiltration
ExoQuick Kit
Extracellular vesicles EVs
79 Vesiclepedia_470 23029346 Fasciola hepatica Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. Fasciola hepatica Protein - Exosomes/Extracellular vesicles/Microvesicles EVs
80 Vesiclepedia_2136 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Macrophage Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
81 Vesiclepedia_2101 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient centrifugation
Small extracellular vesicles Small EVs
82 Vesiclepedia_1927 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
83 Vesiclepedia_2007 35979935 Homo sapiens Serum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients Serum Protein
Lipid
Differential centrifugation Extracellular vesicles EVs
84 Vesiclepedia_1792 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
85 Vesiclepedia_2018 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells Protein Centrifugation Large extracellular vesicles Large EVs
86 Vesiclepedia_2575 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
87 Vesiclepedia_3196 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
88 Vesiclepedia_3289 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
89 Vesiclepedia_1553 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Large EVs
90 Vesiclepedia_2548 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
91 Vesiclepedia_891 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
92 Vesiclepedia_1864 35931686 Homo sapiens Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression Chondrocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
93 Vesiclepedia_1102 24408433 Prochlorococcus marinus Bacterial vesicles in marine ecosystems. Prochlorococcus marinus Lipids Ultrafiltration
Density gradient centrifugation
Ultracentrifugation
Extracellular vesicles EVs
94 Vesiclepedia_2310 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Natural killer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
95 Vesiclepedia_1939 36193887 Homo sapiens Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
96 Vesiclepedia_3036 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
97 Vesiclepedia_2687 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells Protein EVtrap Extracellular vesicles Small EVs
98 Vesiclepedia_3231 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
99 Vesiclepedia_1129 23954818 Homo sapiens Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Squamous carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
100 Vesiclepedia_2570 35260554 Homo sapiens Tumor-derived extracellular vesicles shuttle c-Myc to promote gastric cancer growth and metastasis via the KCNQ1OT1/miR-556-3p/CLIC1 axis Gastric cancer cells Protein Centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
101 Vesiclepedia_2817 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
102 Vesiclepedia_1387 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
103 Vesiclepedia_2888 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
104 Vesiclepedia_1254 24468161 Homo sapiens Molecular characterization of exosome-like vesicles from breast cancer cells. Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
105 Vesiclepedia_1273 24058411 Homo sapiens Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
106 Vesiclepedia_1779 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid Protein Differential centrifugation Extracellular vesicles Large EVs
107 Vesiclepedia_3381 31732668 Homo sapiens Label-free visualization and characterization of extracellular vesicles in breast cancer Breast cancer cells Metabolite Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
108 Vesiclepedia_2301 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Blood Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
109 Vesiclepedia_2786 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone miRNA Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
110 Vesiclepedia_1756 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
111 Vesiclepedia_2409 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Platelets Protein Filtration
Size exclusion chromatography
Extracellular vesicles Small EVs
112 Vesiclepedia_1479 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
113 Vesiclepedia_2953 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes Protein Differential centrifugation Extracellular vesicles Large EVs
114 Vesiclepedia_1965 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
115 Vesiclepedia_1175 29854963 Homo sapiens Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. Urine miRNA qEV size-exclusion column Extracellular vesicles EVs
116 Vesiclepedia_3570 29971917 Rattus norvegicus Leukocytes as a reservoir of circulating oncogenic DNA and regulatory targets of tumor-derived extracellular vesicles Intestinal epithelial cells dsDNA Ultracentrifugation Extracellular vesicles EVs
117 Vesiclepedia_2931 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
118 Vesiclepedia_1880 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
119 Vesiclepedia_3436 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
120 Vesiclepedia_2963 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
121 Vesiclepedia_3110 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells Protein Differential centrifugation Extracellular vesicles Large EVs
122 Vesiclepedia_894 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
123 Vesiclepedia_2795 37309723 Mus musculus Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells T-cell lymphoma cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
124 Vesiclepedia_2711 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Kidney cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
125 Vesiclepedia_2847 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
126 Vesiclepedia_3178 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
127 Vesiclepedia_2961 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
128 Vesiclepedia_3257 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
129 Vesiclepedia_1649 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
130 Vesiclepedia_578 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
131 Vesiclepedia_2146 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Macrophage Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
132 Vesiclepedia_1501 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum Protein
miRNA
ExoQuick Kit Extracellular vesicles Small EVs
133 Vesiclepedia_2091 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
134 Vesiclepedia_2802 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
135 Vesiclepedia_2379 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
136 Vesiclepedia_1377 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Total Exosome Isolation Reagent
Extracellular vesicles Small EVs
137 Vesiclepedia_1026 22327366 Homo sapiens Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Vascular endothelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
138 Vesiclepedia_2495 34370714 Homo sapiens MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression Serum mRNA Polyethylene glycol-based precipitation
Centrifugation
Extracellular vesicles EVs
139 Vesiclepedia_2359 36708245 Homo sapiens Faeces-derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases Blood Protein
Lipid
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
140 Vesiclepedia_1192 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
141 Vesiclepedia_2049 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
142 Vesiclepedia_1582 33785738 Homo sapiens Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Osteosarcoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
143 Vesiclepedia_1616 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Centrifugal ultrafiltration
Immunoaffinity capture
Extracellular vesicles EVs
144 Vesiclepedia_1975 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
145 Vesiclepedia_1789 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells miRNA Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
146 Vesiclepedia_871 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles EVs
147 Vesiclepedia_2545 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Large EVs
148 Vesiclepedia_3348 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Breast cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Small extracellular vesicles Small EVs
149 Vesiclepedia_3519 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma Protein Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
150 Vesiclepedia_2491 34370714 Homo sapiens MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression Wound fluid Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
151 Vesiclepedia_2730 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
152 Vesiclepedia_2543 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
153 Vesiclepedia_1800 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells miRNA Size exclusion chromatography Extracellular vesicles Small EVs
154 Vesiclepedia_1558 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells Protein Centrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
155 Vesiclepedia_1928 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Small extracellular vesicles Small EVs
156 Vesiclepedia_3493 31278254 Mus musculus Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
157 Vesiclepedia_2734 35545056 Mus musculus MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Bone marrow cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
158 Vesiclepedia_939 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
159 Vesiclepedia_2032 36123372 Homo sapiens Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells Glioma stem cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
160 Vesiclepedia_1615 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Centrifugal ultrafiltration
Immunoaffinity capture
Extracellular vesicles EVs
161 Vesiclepedia_2808 34168137 Homo sapiens Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Colorectal cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
162 Vesiclepedia_1956 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
163 Vesiclepedia_2726 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
164 Vesiclepedia_3325 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
165 Vesiclepedia_1717 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
166 Vesiclepedia_1705 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons Protein Differential centrifugation
Ultracentrifugation
Size exclusion chromatography
Extracellular vesicles EVs
167 Vesiclepedia_2836 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
168 Vesiclepedia_2275 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma Protein Filtration
Size exclusion chromatography
Ion exchange adsorption
Centrifugation
Centrifugal ultrafiltration
Small extracellular vesicles Small EVs
169 Vesiclepedia_1847 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma Protein Centrifugation
Filtration
Exo-spin midi
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
170 Vesiclepedia_2547 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
171 Vesiclepedia_588 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
172 Vesiclepedia_2432 29320704 Homo sapiens Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Plasma Protein Ultracentrifugation Extracellular vesicles EVs
173 Vesiclepedia_1166 29904572 Bos taurus A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Bovine milk Protein
miRNA
Differential centrifugation
Density gradient centrifugation
Extracellular vesicles EVs
174 Vesiclepedia_1372 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Total Exosome Isolation Reagent
Extracellular vesicles Small EVs
175 Vesiclepedia_2785 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone miRNA Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
176 Vesiclepedia_3314 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
177 Vesiclepedia_1223 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma Protein Exo-spin Extracellular vesicles EVs
178 Vesiclepedia_2942 35106941 Cricetulus griseus K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Ovarian epithelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
179 Vesiclepedia_2009 35979935 Homo sapiens Serum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients Serum Protein
Lipid
Differential centrifugation Extracellular vesicles EVs
180 Vesiclepedia_2526 34315885 Mus musculus Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Embryonic kidney cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
181 Vesiclepedia_2118 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
182 Vesiclepedia_2959 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes Protein Differential centrifugation Extracellular vesicles Large EVs
183 Vesiclepedia_1785 35927827 Mus musculus Neoantigen-based cancer vaccination using chimeric RNA-loaded dendritic cell-derived extracellular vesicles Dendritic cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
184 Vesiclepedia_2793 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
185 Vesiclepedia_2011 36417867 Homo sapiens Extracellular vesicles carrying HIV-1 Nef induce long-term hyperreactivity of myeloid cells Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
186 Vesiclepedia_984 25287304 Candida albicans Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans. Candida albicans Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
187 Vesiclepedia_2134 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Serum Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
188 Vesiclepedia_1897 36260670 Mus musculus Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice Mesenchymal stem cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
189 Vesiclepedia_3443 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
190 Vesiclepedia_3109 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells Protein Differential centrifugation Extracellular vesicles Large EVs
191 Vesiclepedia_1485 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
192 Vesiclepedia_2587 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
193 Vesiclepedia_2205 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Size exclusion chromatography
Extracellular vesicles Small EVs
194 Vesiclepedia_3246 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung epithelial cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
195 Vesiclepedia_980 25471885 Drosophila melanogaster The ESCRT machinery regulates the secretion and long-range activity of Hedgehog. Drosophila wing imaginal Disc Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
196 Vesiclepedia_2140 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Serum Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
197 Vesiclepedia_2727 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
198 Vesiclepedia_1498 33991177 Homo sapiens Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Gastric cancer cells Protein Differential centrifugation
Ultracentrifugation
Large extracellular vesicles Large EVs
199 Vesiclepedia_611 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
200 Vesiclepedia_2043 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatocytes Protein Differential centrifugation Large extracellular vesicles Large EVs
201 Vesiclepedia_442 22288420 Paracoccidioides brasiliensis Vesicle and vesicle-free extracellular proteome of Paracoccidioides brasiliensis: comparative analysis with other pathogenic fungi. Paracoccidioides brasiliensis Protein - Extracellular vesicles EVs
202 Vesiclepedia_3195 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
203 Vesiclepedia_2357 36708245 Homo sapiens Faeces-derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases Faeces Protein
Lipid
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
204 Vesiclepedia_2843 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
205 Vesiclepedia_2070 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
206 Vesiclepedia_2676 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic duct epithelial cells Protein
Lipid
Metabolite
Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
207 Vesiclepedia_1521 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Embryonic kidney cells miRNA ExoQuick Kit Extracellular vesicles Small EVs
208 Vesiclepedia_2947 35106941 Cricetulus griseus K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Ovarian epithelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
209 Vesiclepedia_3550 35696959 Homo sapiens Utility of cell-free transrenal DNA for the diagnosis of Tuberculous Meningitis: A proof-of-concept study Urine dsDNA Exosome Isolation Kit Extracellular Vesicles EVs
210 Vesiclepedia_1607 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Centrifugal ultrafiltration
Immunoaffinity capture
Extracellular vesicles EVs
211 Vesiclepedia_853 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
212 Vesiclepedia_1213 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultracentrifugation Extracellular vesicles EVs
213 Vesiclepedia_602 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
214 Vesiclepedia_2390 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
215 Vesiclepedia_2933 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
216 Vesiclepedia_2057 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
217 Vesiclepedia_873 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles EVs
218 Vesiclepedia_1720 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
219 Vesiclepedia_1646 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Forebrain neurons Protein
Lipid
Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
220 Vesiclepedia_2864 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
221 Vesiclepedia_3225 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
222 Vesiclepedia_1397 32939236 Homo sapiens Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Saliva Protein
Lipid
Differential centrifugation
Tangential flow filtration
Size exclusion chromatography
Extracellular vesicles Small EVs
223 Vesiclepedia_1255 24468161 Homo sapiens Molecular characterization of exosome-like vesicles from breast cancer cells. Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
224 Vesiclepedia_2884 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Serum Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
225 Vesiclepedia_3202 34596354 Homo sapiens Extracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p Mesenchymal stem cells Protein
miRNA
Tangential flow filtration Extracellular vesicles Small EVs
226 Vesiclepedia_2196 29511463 Bos taurus Biocompatibility of highly purified bovine milk-derived extracellular vesicles Bovine milk Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
227 Vesiclepedia_2728 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
228 Vesiclepedia_603 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
229 Vesiclepedia_3525 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma Protein Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
230 Vesiclepedia_2408 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Adipocytes Protein Filtration
Size exclusion chromatography
Extracellular vesicles Small EVs
231 Vesiclepedia_1583 33686255 Homo sapiens Extracellular vesicle drug occupancy enables real-time monitoring of targeted cancer therapy. Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
232 Vesiclepedia_845 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
233 Vesiclepedia_1384 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
234 Vesiclepedia_2819 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
235 Vesiclepedia_2829 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
236 Vesiclepedia_3317 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
237 Vesiclepedia_2958 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes Protein Differential centrifugation Extracellular vesicles Large EVs
238 Vesiclepedia_2517 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma Protein Size exclusion chromatography Extracellular vesicles EVs
239 Vesiclepedia_2780 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone Protein Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
240 Vesiclepedia_3085 35665306 Mus musculus Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles Serum Protein Size exclusion chromatography
Ultracentrifugation
Extracellular vesicles Small EVs
241 Vesiclepedia_3310 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
242 Vesiclepedia_2714 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
243 Vesiclepedia_569 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (CD9 FT)
Extracellular vesicles EVs
244 Vesiclepedia_1890 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
245 Vesiclepedia_2416 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
246 Vesiclepedia_931 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urothelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
247 Vesiclepedia_3423 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Centrifugal ultrafiltration
Size exclusion chromatography
Extracellular vesicles Small EVs
248 Vesiclepedia_3500 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets Protein Differential centrifugation Extracellular vesicles EVs
249 Vesiclepedia_3288 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
250 Vesiclepedia_1515 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum miRNA ExoQuick Kit Extracellular vesicles Small EVs
251 Vesiclepedia_2385 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
252 Vesiclepedia_3365 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colon cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Small extracellular vesicles Small EVs
253 Vesiclepedia_2141 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Serum Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
254 Vesiclepedia_3484 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid Protein Differential centrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
255 Vesiclepedia_3207 34957415 Mus musculus Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
256 Vesiclepedia_3433 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Centrifugal ultrafiltration
Size exclusion chromatography
Extracellular vesicles Small EVs
257 Vesiclepedia_991 25138791 Homo sapiens The exocyst and regulatory GTPases in urinary exosomes. Urine Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
258 Vesiclepedia_3473 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ovarian cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
259 Vesiclepedia_2484 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
260 Vesiclepedia_2376 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
261 Vesiclepedia_1563 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
262 Vesiclepedia_2927 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
263 Vesiclepedia_607 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
264 Vesiclepedia_3263 34654817 Rattus norvegicus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Plasma Protein ExoQuick Kit Small extracellular vesicles EVs
265 Vesiclepedia_3530 30936474 Homo sapiens Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells Macrophage lncRNA Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
266 Vesiclepedia_2103 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient centrifugation
Small extracellular vesicles Small EVs
267 Vesiclepedia_2396 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
268 Vesiclepedia_2311 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles B cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
269 Vesiclepedia_3474 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ovarian cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
270 Vesiclepedia_3184 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
271 Vesiclepedia_1565 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
272 Vesiclepedia_1854 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma Protein Centrifugation
Filtration
Exo-spin midi
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
273 Vesiclepedia_2483 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
274 Vesiclepedia_2225 34596356 Homo sapiens Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Primary prostate stromal cells mRNA Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
275 Vesiclepedia_2555 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
276 Vesiclepedia_1878 36063142 Homo sapiens Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
277 Vesiclepedia_3168 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
278 Vesiclepedia_1493 33991177 Homo sapiens Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Gastric cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
279 Vesiclepedia_2787 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone miRNA Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
280 Vesiclepedia_3203 34596354 Homo sapiens Extracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p Mesenchymal stem cells Protein Tangential flow filtration Extracellular vesicles Small EVs
281 Vesiclepedia_2520 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma Protein OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles EVs
282 Vesiclepedia_1584 33692129 Macaca fascicularis Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates Mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Small extracellular vesicles Small EVs
283 Vesiclepedia_624 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
284 Vesiclepedia_3220 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
285 Vesiclepedia_1370 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Total Exosome Isolation Reagent
Extracellular vesicles Small EVs
286 Vesiclepedia_3425 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Centrifugal ultrafiltration
Size exclusion chromatography
Extracellular vesicles Small EVs
287 Vesiclepedia_3248 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
288 Vesiclepedia_3322 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
289 Vesiclepedia_2706 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
290 Vesiclepedia_2960 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
291 Vesiclepedia_2329 32487994 Homo sapiens Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence Plasma Protein Centrifugation
Size exclusion chromatography
Extracellular vesicles Small EVs
292 Vesiclepedia_1977 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
293 Vesiclepedia_1415 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
294 Vesiclepedia_2263 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
295 Vesiclepedia_2300 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Monocytes Protein
miRNA
Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
296 Vesiclepedia_3548 34575975 Homo sapiens Teriflunomide Inhibits JCPyV Infection and Spread in Glial Cells and Choroid Plexus Epithelial Cells Plasma dsDNA Size exclusion chromatography
Ultrafiltration
Extracellular Vesicles EVs
297 Vesiclepedia_2536 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein Centrifugation Extracellular vesicles Large EVs
298 Vesiclepedia_615 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
299 Vesiclepedia_1241 25329303 Homo sapiens Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. Urine Protein Vn96 peptide precipitation Extracellular vesicles EVs
300 Vesiclepedia_2085 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
301 Vesiclepedia_568 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (CD9 PD)
Extracellular vesicles EVs
302 Vesiclepedia_2832 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
303 Vesiclepedia_3094 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
304 Vesiclepedia_3518 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma Protein Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
305 Vesiclepedia_1239 25329303 Homo sapiens Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. Urine Protein Vn96 peptide precipitation Extracellular vesicles EVs
306 Vesiclepedia_2050 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
307 Vesiclepedia_3291 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
308 Vesiclepedia_3489 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid Protein Immunoaffinity capture
Centrifugation
Extracellular vesicles Small EVs
309 Vesiclepedia_3319 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
310 Vesiclepedia_2288 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Natural killer cells Protein Polyethylene glycol-based precipitation
Centrifugation
Dialysis
Extracellular vesicles Small EVs
311 Vesiclepedia_1798 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
312 Vesiclepedia_1844 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
313 Vesiclepedia_849 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
314 Vesiclepedia_1605 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Differential centrifugation Extracellular vesicles Large EVs
315 Vesiclepedia_1581 33785738 Homo sapiens Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Osteosarcoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
316 Vesiclepedia_2157 34140472 Amblyomma americanum Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Amblyomma americanum Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
317 Vesiclepedia_1635 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells Protein Differential centrifugation Extracellular vesicles Large EVs
318 Vesiclepedia_2905 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells Protein Filtration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
319 Vesiclepedia_548 24009880 Homo sapiens Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. Mast cells mRNA - Exosomes/Extracellular vesicles EVs
320 Vesiclepedia_1752 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
321 Vesiclepedia_1240 25329303 Homo sapiens Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. Urine Protein Ultracentrifugation Extracellular vesicles EVs
322 Vesiclepedia_567 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (Igg1 FT)
Extracellular vesicles EVs
323 Vesiclepedia_855 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
324 Vesiclepedia_2013 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells Protein Differential centrifugation Medium extracellular vesicles Large EVs
325 Vesiclepedia_3329 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
326 Vesiclepedia_2047 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Plasma Protein Differential centrifugation Large extracellular vesicles Large EVs
327 Vesiclepedia_2042 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatocytes Protein Differential centrifugation Large extracellular vesicles Large EVs
328 Vesiclepedia_1905 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
329 Vesiclepedia_3487 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid Protein Differential centrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
330 Vesiclepedia_3293 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
331 Vesiclepedia_2374 35087866 Rattus norvegicus Exercise-Induced Extracellular Vesicles Delay the Progression of Prostate Cancer Plasma RNA Size exclusion chromatography
Filtration
Extracellular vesicles Small EVs
332 Vesiclepedia_3217 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
333 Vesiclepedia_2078 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
334 Vesiclepedia_3549 31684971 Homo sapiens Detection of fetal trisomy and single gene disease by massively parallel sequencing of extracellular vesicle DNA in maternal plasma: a proof-of-concept validation Plasma dsDNA ExoQuick Kit Extracellular Vesicles EVs
335 Vesiclepedia_2527 34315885 Mus musculus Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Kidney epithelial cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
336 Vesiclepedia_2121 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
337 Vesiclepedia_3256 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
338 Vesiclepedia_2119 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
339 Vesiclepedia_3043 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts Protein Centrifugation
Polyethylene glycol-based precipitation
Extracellular vesicles EVs
340 Vesiclepedia_1190 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
341 Vesiclepedia_2258 37376799 Bos taurus Bovine milk-derived extracellular vesicles enhance doxorubicin sensitivity in triple negative breast cancer cells by targeting metabolism and STAT signalling Bovine milk Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
342 Vesiclepedia_1618 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Large EVs
343 Vesiclepedia_2083 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
344 Vesiclepedia_1554 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
345 Vesiclepedia_2932 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
346 Vesiclepedia_2833 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
347 Vesiclepedia_1186 28326167 Homo sapiens Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment. Urine Protein Hydrostatic filtration dialysis
Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
348 Vesiclepedia_2366 36759608 Mus musculus Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo Adipocytes Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
349 Vesiclepedia_1866 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
350 Vesiclepedia_2848 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
351 Vesiclepedia_1381 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
352 Vesiclepedia_2309 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Natural killer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
353 Vesiclepedia_1300 - Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
354 Vesiclepedia_1930 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Small extracellular vesicles Small EVs
355 Vesiclepedia_2731 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
356 Vesiclepedia_2383 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
357 Vesiclepedia_2398 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
358 Vesiclepedia_2792 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
359 Vesiclepedia_2883 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Serum Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
360 Vesiclepedia_1227 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma Protein Size exclusion chromatography Extracellular vesicles EVs
361 Vesiclepedia_3307 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
362 Vesiclepedia_1058 30035390 Mus musculus Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Mouse embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
363 Vesiclepedia_2186 33792189 Mus musculus A novel role for milk fat globule-EGF factor 8 protein (MFGE8) in the mediation of mouse sperm-extracellular vesicle interactions Epididymal epithelial cells Protein Filtration
Tangential flow filtration
OptiPrep density gradient centrifugation
Ultracentrifugation
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
364 Vesiclepedia_1386 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
365 Vesiclepedia_1576 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
366 Vesiclepedia_625 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
367 Vesiclepedia_3224 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
368 Vesiclepedia_2810 34168137 Homo sapiens Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Colorectal cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
369 Vesiclepedia_1049 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
370 Vesiclepedia_1422 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
371 Vesiclepedia_2113 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
372 Vesiclepedia_1176 29854963 Homo sapiens Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. Urine miRNA qEV size-exclusion column Extracellular vesicles EVs
373 Vesiclepedia_1617 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Large EVs
374 Vesiclepedia_3457 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Fibroblasts miRNA Filtration
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
375 Vesiclepedia_469 23029346 Echinostoma caproni Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. Echinostoma caproni Protein - Exosomes/Extracellular vesicles/Microvesicles EVs
376 Vesiclepedia_2199 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Size exclusion chromatography
Extracellular vesicles Small EVs
377 Vesiclepedia_2046 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Fibroblasts Protein Differential centrifugation Large extracellular vesicles Large EVs
378 Vesiclepedia_594 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
379 Vesiclepedia_2222 34596356 Homo sapiens Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Primary prostate stromal cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
380 Vesiclepedia_2079 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
381 Vesiclepedia_1931 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
382 Vesiclepedia_3469 35393416 Homo sapiens CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity Oral cancer cells Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
383 Vesiclepedia_2688 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells Protein EVtrap Extracellular vesicles Small EVs
384 Vesiclepedia_1486 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
385 Vesiclepedia_1763 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid Protein Differential centrifugation Extracellular vesicles Large EVs
386 Vesiclepedia_2677 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic duct epithelial cells Protein
Lipid
Metabolite
Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
387 Vesiclepedia_2689 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells Protein EVtrap Extracellular vesicles Small EVs
388 Vesiclepedia_3096 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
389 Vesiclepedia_1963 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
390 Vesiclepedia_1429 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
391 Vesiclepedia_3538 27441821 Homo sapiens BARHL2 Methylation Using Gastric Wash DNA or Gastric Juice Exosomal DNA is a Useful Marker For Early Detection of Gastric Cancer in an H. pylori-Independent Manner Gastric washes dsDNA ExoQuick Kit Extracellular Vesicles EVs
392 Vesiclepedia_2206 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Size exclusion chromatography
Extracellular vesicles Small EVs
393 Vesiclepedia_628 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
394 Vesiclepedia_582 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
395 Vesiclepedia_2851 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
396 Vesiclepedia_2418 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
397 Vesiclepedia_2197 33828139 Bos taurus Extracellular vesicles isolated from milk can improve gut barrier dysfunction induced by malnutrition Bovine milk Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
398 Vesiclepedia_745 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles EVs
399 Vesiclepedia_2195 29511463 Bos taurus Biocompatibility of highly purified bovine milk-derived extracellular vesicles Bovine milk Protein Acidification
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
400 Vesiclepedia_626 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
401 Vesiclepedia_2898 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells Protein Filtration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
402 Vesiclepedia_859 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
403 Vesiclepedia_3574 36289852 Homo sapiens Next-Generation Sequencing Comparative Analysis of DNA Mutations between Blood-Derived Extracellular Vesicles and Matched Cancer Tissue in Patients with Grade 4 Glioblastoma Plasma dsDNA-mutated ExoEasy Maxi Kit Extracellular Vesicles EVs
404 Vesiclepedia_546 23983189 Homo sapiens Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. B cells Protein - Exosomes/Extracellular vesicles/Microvesicles EVs
405 Vesiclepedia_1195 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
406 Vesiclepedia_3316 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
407 Vesiclepedia_1873 36063142 Homo sapiens Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
408 Vesiclepedia_2171 29643357 Staphylococcus aureus Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform Staphylococcus aureus Protein Filtration
Tangential flow filtration
OptiPrep density gradient centrifugation
Ultracentrifugation
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
409 Vesiclepedia_1472 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Extracellular vesicles Small EVs
410 Vesiclepedia_3101 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
411 Vesiclepedia_1948 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
412 Vesiclepedia_750 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles EVs
413 Vesiclepedia_1904 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
414 Vesiclepedia_2799 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
415 Vesiclepedia_3190 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
416 Vesiclepedia_2723 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
417 Vesiclepedia_2936 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
418 Vesiclepedia_2330 32487994 Homo sapiens Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence Plasma Protein Centrifugation
Size exclusion chromatography
Extracellular vesicles Small EVs
419 Vesiclepedia_2582 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
420 Vesiclepedia_906 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Urothelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
421 Vesiclepedia_1211 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultrafiltration
Size exclusion chromatography
Extracellular vesicles EVs
422 Vesiclepedia_3187 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
423 Vesiclepedia_3526 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma Protein Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
424 Vesiclepedia_1988 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
425 Vesiclepedia_866 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles EVs
426 Vesiclepedia_2082 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
427 Vesiclepedia_1362 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Large EVs
428 Vesiclepedia_1754 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
429 Vesiclepedia_2724 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
430 Vesiclepedia_1985 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
431 Vesiclepedia_1801 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells miRNA Size exclusion chromatography Extracellular vesicles Small EVs
432 Vesiclepedia_2384 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
433 Vesiclepedia_571 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (CD63 FT)
Extracellular vesicles EVs
434 Vesiclepedia_1404 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells Protein Differential centrifugation
Tangential flow filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
435 Vesiclepedia_604 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
436 Vesiclepedia_1969 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Extracellular vesicles Small EVs
437 Vesiclepedia_1885 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
438 Vesiclepedia_592 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
439 Vesiclepedia_3573 36125881 Mus musculus Cell-free DNA topology depends on its subcellular and cellular origins in cancer Plasma mtDNA Differential centrifugation Extracellular Vesicles EVs
440 Vesiclepedia_1645 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Forebrain neurons Protein
Lipid
Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
441 Vesiclepedia_597 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
442 Vesiclepedia_3264 34654817 Mus musculus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Microglia miRNA Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
443 Vesiclepedia_3504 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets Protein Differential centrifugation Extracellular vesicles EVs
444 Vesiclepedia_1037 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
miRCURY Exosome Isolation Kit Extracellular vesicles EVs
445 Vesiclepedia_955 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
446 Vesiclepedia_3442 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
447 Vesiclepedia_1797 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells miRNA Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
448 Vesiclepedia_3176 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
449 Vesiclepedia_3037 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
450 Vesiclepedia_2087 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
451 Vesiclepedia_631 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
452 Vesiclepedia_1857 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma Protein Centrifugation
Filtration
Exo-spin midi
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
453 Vesiclepedia_1594 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Centrifugal ultrafiltration
Immunoaffinity capture
Extracellular vesicles EVs
454 Vesiclepedia_3373 33510128 Mus musculus Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer cachexia Colon cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
455 Vesiclepedia_2448 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells miRNA Centrifugation
Ultracentrifugation
Extracellular vesicles EVs
456 Vesiclepedia_2715 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
457 Vesiclepedia_1596 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Centrifugal ultrafiltration
Immunoaffinity capture
Extracellular vesicles EVs
458 Vesiclepedia_3583 33375577 Homo sapiens Comparison of Circulating Tumour DNA and Extracellular Vesicle DNA by Low-Pass Whole-Genome Sequencing Reveals Molecular Drivers of Disease in a Breast Cancer Patient Plasma dsDNA-mutated Differential centrifugation
Ultracentrifugation
Extracellular Vesicles EVs
459 Vesiclepedia_632 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
460 Vesiclepedia_2580 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
461 Vesiclepedia_2435 29320704 Homo sapiens Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Plasma Protein Centrifugation Extracellular vesicles EVs
462 Vesiclepedia_920 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
463 Vesiclepedia_2720 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
464 Vesiclepedia_1972 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
465 Vesiclepedia_1389 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
466 Vesiclepedia_2516 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma Protein OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Large EVs
467 Vesiclepedia_3422 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Centrifugal ultrafiltration
Size exclusion chromatography
Extracellular vesicles Small EVs
468 Vesiclepedia_1491 32024826 Homo sapiens Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Plasma miRNA Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
469 Vesiclepedia_1376 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Total Exosome Isolation Reagent
Extracellular vesicles Small EVs
470 Vesiclepedia_3496 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets Protein Differential centrifugation Extracellular vesicles EVs
471 Vesiclepedia_872 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles EVs
472 Vesiclepedia_3087 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
473 Vesiclepedia_2401 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
474 Vesiclepedia_1938 36193887 Homo sapiens Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
475 Vesiclepedia_3453 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
476 Vesiclepedia_3287 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
477 Vesiclepedia_2107 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
478 Vesiclepedia_909 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Transitional carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
479 Vesiclepedia_3523 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma Protein Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
480 Vesiclepedia_2881 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Serum Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
481 Vesiclepedia_2080 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
482 Vesiclepedia_1629 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons Protein
Lipid
Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
483 Vesiclepedia_417 20956325 Bacillus anthracis Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins. Bacillus anthracis Lipids - Extracellular vesicles EVs
484 Vesiclepedia_484 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Epimastigotes Protein - Exosomes/Extracellular vesicles/Ectosomes EVs
485 Vesiclepedia_627 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
486 Vesiclepedia_1050 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
487 Vesiclepedia_1783 35932288 Homo sapiens Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
488 Vesiclepedia_1402 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells Protein Differential centrifugation
Tangential flow filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
489 Vesiclepedia_2885 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
490 Vesiclepedia_616 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
491 Vesiclepedia_1919 36303008 Homo sapiens A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples Lung cancer cells Protein Filtration
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
492 Vesiclepedia_3430 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
493 Vesiclepedia_3098 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
494 Vesiclepedia_2783 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone miRNA ExoQuick Kit Extracellular vesicles Small EVs
495 Vesiclepedia_1505 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum Protein Centrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
496 Vesiclepedia_3463 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells miRNA Filtration
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
497 Vesiclepedia_3180 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
498 Vesiclepedia_486 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles EVs
499 Vesiclepedia_1171 29881354 Rattus norvegicus Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. Serum Protein
miRNA
ExoQuick Extracellular vesicles EVs
500 Vesiclepedia_1863 35931686 Homo sapiens Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression Chondrocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
501 Vesiclepedia_2860 33579909 Mus musculus Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
502 Vesiclepedia_1183 28684402 Homo sapiens BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells Melanoma cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles EVs
503 Vesiclepedia_2535 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein Centrifugation Extracellular vesicles Large EVs
504 Vesiclepedia_2561 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
505 Vesiclepedia_3387 31732668 Homo sapiens Label-free visualization and characterization of extracellular vesicles in breast cancer Breast cancer cells Metabolite - Extracellular vesicles Small EVs
506 Vesiclepedia_2609 32383290 Ovis aries Quantitative Proteomic Analysis of Seminal Plasma, Sperm Membrane Proteins, and Seminal Extracellular Vesicles Suggests Vesicular Mechanisms Aid in the Removal and Addition of Proteins to the Ram Sperm Membrane Seminal plasma Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles EVs
507 Vesiclepedia_2790 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Liver miRNA Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
508 Vesiclepedia_3449 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
509 Vesiclepedia_1509 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum Protein Centrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
510 Vesiclepedia_2928 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
511 Vesiclepedia_2211 37043568 Bos taurus Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis Bovine milk Protein Differential centrifugation
Ultracentrifugation
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
512 Vesiclepedia_1238 25329303 Homo sapiens Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. Urine Protein Ultracentrifugation Extracellular vesicles EVs
513 Vesiclepedia_1923 36214496 Mus musculus Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Motor neuron-like cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
514 Vesiclepedia_2704 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
515 Vesiclepedia_2591 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
516 Vesiclepedia_1894 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
517 Vesiclepedia_3424 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Centrifugal ultrafiltration
Size exclusion chromatography
Extracellular vesicles Small EVs
518 Vesiclepedia_2056 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
519 Vesiclepedia_3312 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
520 Vesiclepedia_3512 31068461 Homo sapiens Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
521 Vesiclepedia_623 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
522 Vesiclepedia_2417 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
523 Vesiclepedia_956 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
524 Vesiclepedia_3092 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
525 Vesiclepedia_3265 34654817 Mus musculus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Microglia miRNA Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
526 Vesiclepedia_1726 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
527 Vesiclepedia_2556 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
528 Vesiclepedia_1392 32939236 Homo sapiens Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Saliva Protein Differential centrifugation
Tangential flow filtration
Size exclusion chromatography
Extracellular vesicles Small EVs
529 Vesiclepedia_1210 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultrafiltration
Size exclusion chromatography
Extracellular vesicles EVs
530 Vesiclepedia_942 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
531 Vesiclepedia_2805 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
532 Vesiclepedia_3462 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells miRNA Filtration
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
533 Vesiclepedia_1887 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
534 Vesiclepedia_1314 - Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
535 Vesiclepedia_2563 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
536 Vesiclepedia_1024 22327366 Homo sapiens Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Vascular endothelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
537 Vesiclepedia_3182 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
538 Vesiclepedia_1065 29963299 Homo sapiens Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography. Synovial fluid Protein Size exclusion chromatography Extracellular vesicles EVs
539 Vesiclepedia_3501 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets Protein Differential centrifugation Extracellular vesicles EVs
540 Vesiclepedia_2511 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells Protein OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles EVs
541 Vesiclepedia_1511 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum Protein Centrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
542 Vesiclepedia_1313 - Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
543 Vesiclepedia_2044 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
544 Vesiclepedia_2290 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Acute lymphoblastic leukemia cells Protein Polyethylene glycol-based precipitation
Centrifugation
Dialysis
Extracellular vesicles Small EVs
545 Vesiclepedia_857 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
546 Vesiclepedia_1852 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma Protein Centrifugation
Filtration
Exo-spin midi
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
547 Vesiclepedia_1474 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Extracellular vesicles Small EVs
548 Vesiclepedia_1265 24310399 Homo sapiens Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. Glioblastoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles EVs
549 Vesiclepedia_1886 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
550 Vesiclepedia_2094 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
551 Vesiclepedia_2550 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
552 Vesiclepedia_3214 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanocytes Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
553 Vesiclepedia_2736 35545056 Mus musculus MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Bone marrow cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
554 Vesiclepedia_1966 35915084 Mus musculus Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
555 Vesiclepedia_3454 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells miRNA Filtration
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
556 Vesiclepedia_3492 31278254 Mus musculus Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
557 Vesiclepedia_596 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
558 Vesiclepedia_414 20559436 Saccharomyces cerevisiae Characterization of yeast extracellular vesicles: evidence for the participation of different pathways of cellular traffic in vesicle biogenesis. Saccharomyces cerevisiae Protein - Extracellular vesicles EVs
559 Vesiclepedia_650 29188495 Homo sapiens Protein Biomarkers and Neuroproteomics Characterization of Microvesicles/Exosomes from Human Cerebrospinal Fluid Following Traumatic Brain Injury. Cerebrospinal fluid Protein Differential centrifugation
Ultracentrifugation
Sonication
Filtration
Extracellular vesicles EVs
560 Vesiclepedia_2143 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Macrophage Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
561 Vesiclepedia_3465 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells miRNA Filtration
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
562 Vesiclepedia_2863 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
563 Vesiclepedia_2126 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
564 Vesiclepedia_1796 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
565 Vesiclepedia_243 22149170 Homo sapiens The Protein Interaction Network of Extracellular Vesicles Derived from Human Colorectal Cancer Cells Colorectal cancer cells Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
566 Vesiclepedia_2934 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
567 Vesiclepedia_2904 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells Protein Filtration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
568 Vesiclepedia_2532 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein Centrifugation Extracellular vesicles Large EVs
569 Vesiclepedia_1855 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma Protein Centrifugation
Filtration
Exo-spin midi
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
570 Vesiclepedia_3105 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
571 Vesiclepedia_1744 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
572 Vesiclepedia_586 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
573 Vesiclepedia_1755 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
574 Vesiclepedia_3467 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells miRNA Filtration
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
575 Vesiclepedia_2226 34596356 Homo sapiens Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Primary prostate stromal cells mRNA Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
576 Vesiclepedia_630 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
577 Vesiclepedia_2269 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma Protein Filtration
Size exclusion chromatography
Ion exchange adsorption
Centrifugation
Centrifugal ultrafiltration
Small extracellular vesicles Small EVs
578 Vesiclepedia_2814 34168137 Homo sapiens Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
579 Vesiclepedia_581 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
580 Vesiclepedia_1633 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells Protein Differential centrifugation Extracellular vesicles Large EVs
581 Vesiclepedia_2854 33579909 Homo sapiens Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
582 Vesiclepedia_2525 34315885 Mus musculus Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Embryonic kidney cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
583 Vesiclepedia_2100 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient centrifugation
Small extracellular vesicles Small EVs
584 Vesiclepedia_1383 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
585 Vesiclepedia_2494 34370714 Homo sapiens MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression Serum mRNA Polyethylene glycol-based precipitation
Centrifugation
Extracellular vesicles EVs
586 Vesiclepedia_3327 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
587 Vesiclepedia_908 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Transitional carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
588 Vesiclepedia_856 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
589 Vesiclepedia_2939 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
590 Vesiclepedia_952 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
591 Vesiclepedia_1194 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
592 Vesiclepedia_1033 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
qEV size-exclusion column Extracellular vesicles EVs
593 Vesiclepedia_549 24009881 Homo sapiens Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles/Ectosomes EVs
594 Vesiclepedia_3503 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets Protein Differential centrifugation Extracellular vesicles EVs
595 Vesiclepedia_3321 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
596 Vesiclepedia_2317 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Plasma Protein
small RNA
ExoQuick Kit Extracellular vesicles/Exosomes EVs
597 Vesiclepedia_2132 36515353 Homo sapiens Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Plasma Metabolite
Protein
ExoQuick Kit
Centrifugation
Extracellular vesicles Small EVs
598 Vesiclepedia_3041 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts Protein Centrifugation
Polyethylene glycol-based precipitation
Extracellular vesicles EVs
599 Vesiclepedia_2572 35689797 Homo sapiens Proteomic alterations in extracellular vesicles induced by oncogenic PIK3CA mutations Mammary epithelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
600 Vesiclepedia_1380 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
601 Vesiclepedia_2876 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
602 Vesiclepedia_2019 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells Protein Differential centrifugation Medium extracellular vesicles Large EVs
603 Vesiclepedia_2291 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Glioma cells Protein Polyethylene glycol-based precipitation
Centrifugation
Dialysis
Extracellular vesicles Small EVs
604 Vesiclepedia_2880 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Melanoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
605 Vesiclepedia_3529 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma Protein Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
606 Vesiclepedia_1564 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
607 Vesiclepedia_3427 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
608 Vesiclepedia_1651 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
609 Vesiclepedia_3546 36149031 Homo sapiens Extracellular vesicle-bound DNA in urine is indicative of kidney allograft injury Urine dsDNA Size exclusion chromatography Extracellular Vesicles EVs
610 Vesiclepedia_576 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
611 Vesiclepedia_1711 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons Protein Differential centrifugation
Ultracentrifugation
Size exclusion chromatography
Extracellular vesicles EVs
612 Vesiclepedia_1599 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Centrifugal ultrafiltration
Immunoaffinity capture
Extracellular vesicles EVs
613 Vesiclepedia_934 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Bladder cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
614 Vesiclepedia_2583 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung epithelial cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
615 Vesiclepedia_2797 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
616 Vesiclepedia_3179 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
617 Vesiclepedia_2410 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Hepatocytes Protein Filtration
Size exclusion chromatography
Extracellular vesicles Small EVs
618 Vesiclepedia_2861 33579909 Mus musculus Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
619 Vesiclepedia_1177 29854963 Homo sapiens Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. Urine miRNA qEV size-exclusion column Extracellular vesicles EVs
620 Vesiclepedia_1620 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
621 Vesiclepedia_2128 36515353 Homo sapiens Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Plasma Protein ExoQuick Kit
Centrifugation
Extracellular vesicles Small EVs
622 Vesiclepedia_2393 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
623 Vesiclepedia_1891 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
624 Vesiclepedia_2411 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Leukocytes Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
625 Vesiclepedia_1405 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells Protein Differential centrifugation
Tangential flow filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
626 Vesiclepedia_3515 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma Protein Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
627 Vesiclepedia_2887 30918259 Mus musculus Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
628 Vesiclepedia_1946 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
629 Vesiclepedia_1039 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Extracellular vesicles EVs
630 Vesiclepedia_2571 35689797 Homo sapiens Proteomic alterations in extracellular vesicles induced by oncogenic PIK3CA mutations Mammary epithelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
631 Vesiclepedia_591 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
632 Vesiclepedia_1918 36303008 Homo sapiens A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples Epidermoid cancer cells Protein Filtration
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
633 Vesiclepedia_3318 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
634 Vesiclepedia_2593 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung epithelial cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
635 Vesiclepedia_1644 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
636 Vesiclepedia_1976 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
637 Vesiclepedia_3167 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
638 Vesiclepedia_2530 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein Centrifugation Extracellular vesicles Large EVs
639 Vesiclepedia_2059 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
640 Vesiclepedia_2503 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells Protein exoEasy Maxi Kit Extracellular vesicles EVs
641 Vesiclepedia_932 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Bladder cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
642 Vesiclepedia_2538 34293122 Mus musculus Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein
Lipid
Centrifugation Extracellular vesicles Large EVs
643 Vesiclepedia_1883 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
644 Vesiclepedia_502 23436686 Homo sapiens A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Endothelial cells Protein - Membrane vesicles/Extracellular vesicles EVs
645 Vesiclepedia_1182 28684402 Homo sapiens BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells Melanoma cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles EVs
646 Vesiclepedia_1941 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
647 Vesiclepedia_2482 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
648 Vesiclepedia_3255 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
649 Vesiclepedia_3324 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
650 Vesiclepedia_3452 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
651 Vesiclepedia_1393 32939236 Homo sapiens Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Saliva Protein Differential centrifugation
Tangential flow filtration
Size exclusion chromatography
Extracellular vesicles Small EVs
652 Vesiclepedia_3108 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells Protein Differential centrifugation Extracellular vesicles Large EVs
653 Vesiclepedia_1309 - Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
654 Vesiclepedia_2788 35304471 Homo sapiens Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
655 Vesiclepedia_2850 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
656 Vesiclepedia_1730 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
657 Vesiclepedia_2048 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Plasma Protein Differential centrifugation Large extracellular vesicles Large EVs
658 Vesiclepedia_1042 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Extracellular vesicles EVs
659 Vesiclepedia_2924 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
660 Vesiclepedia_1165 29904572 Bos taurus A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Bovine milk Protein
miRNA
Differential centrifugation
Density gradient centrifugation
Extracellular vesicles EVs
661 Vesiclepedia_3165 34772807 Clonorchis sinensis Csi-let-7a-5p delivered by extracellular vesicles from a liver fluke activates M1-like macrophages and exacerbates biliary injuries Clonorchis sinensis miRNA Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
662 Vesiclepedia_1909 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
663 Vesiclepedia_2712 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Kidney cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
664 Vesiclepedia_1423 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
665 Vesiclepedia_1986 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
666 Vesiclepedia_889 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
667 Vesiclepedia_2778 35304471 Homo sapiens Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone Protein Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
668 Vesiclepedia_605 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
669 Vesiclepedia_3227 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
670 Vesiclepedia_2794 37309723 Mus musculus Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Colon cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
671 Vesiclepedia_2796 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
672 Vesiclepedia_1971 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Extracellular vesicles Small EVs
673 Vesiclepedia_2877 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Melanoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
674 Vesiclepedia_2859 33579909 Mus musculus Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
675 Vesiclepedia_3268 34654817 Rattus norvegicus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Plasma Protein ExoQuick Kit Small extracellular vesicles EVs
676 Vesiclepedia_3417 33391636 Homo sapiens Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus Embryonic kidney cells Protein Differential centrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
677 Vesiclepedia_2224 34596356 Homo sapiens Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Primary prostate stromal cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
678 Vesiclepedia_2492 34370714 Homo sapiens MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression Wound fluid Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
679 Vesiclepedia_2364 36748335 Homo sapiens Hypoxia promotes EV secretion by impairing lysosomal homeostasis in HNSCC through negative regulation of ATP6V1A by HIF-1α Oral cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
680 Vesiclepedia_1648 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
681 Vesiclepedia_1575 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
682 Vesiclepedia_1729 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
683 Vesiclepedia_893 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
684 Vesiclepedia_2392 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
685 Vesiclepedia_2853 33579909 Homo sapiens Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
686 Vesiclepedia_1361 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Large EVs
687 Vesiclepedia_3567 28750687 Homo sapiens Extracellular vesicles from human liver stem cells restore argininosuccinate synthase deficiency Liver stem cells dsDNA Differential centrifugation
Ultracentrifugation
Extracellular vesicles|Exosomes EVs
688 Vesiclepedia_2595 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
689 Vesiclepedia_3485 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid Protein Differential centrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
690 Vesiclepedia_1877 36063142 Homo sapiens Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
691 Vesiclepedia_2223 34596356 Homo sapiens Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Primary prostate stromal cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
692 Vesiclepedia_2033 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
693 Vesiclepedia_3566 36555692 Homo sapiens Intravesicular Genomic DNA Enriched by Size Exclusion Chromatography Can Enhance Lung Cancer Oncogene Mutation Detection Sensitivity Lung cancer cells DNA Sucrose density gradient Ultracentrifugation
size exclusion chromatography
Extracellular vesicles EVs
694 Vesiclepedia_1473 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Extracellular vesicles Small EVs
695 Vesiclepedia_1987 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
696 Vesiclepedia_1787 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Primary cortical neurons Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
697 Vesiclepedia_2270 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma Protein Filtration
Size exclusion chromatography
Centrifugal ultrafiltration
Small extracellular vesicles Small EVs
698 Vesiclepedia_1757 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
699 Vesiclepedia_1900 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
700 Vesiclepedia_1737 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
701 Vesiclepedia_3243 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
702 Vesiclepedia_1492 32024826 Homo sapiens Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Plasma miRNA Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
703 Vesiclepedia_840 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
704 Vesiclepedia_462 22849433 Homo sapiens Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types. Embryonic kidney cells miRNA - Extracellular vesicles EVs
705 Vesiclepedia_3458 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Primary cardiosphere-derived cells miRNA Filtration
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
706 Vesiclepedia_3170 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
707 Vesiclepedia_1625 34012515 Homo sapiens CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells Melanoma cells Protein Differential centrifugation
Centrifugal ultrafiltration
Size exclusion chromatography
Extracellular vesicles EVs
708 Vesiclepedia_1780 35932288 Homo sapiens Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
709 Vesiclepedia_2839 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
710 Vesiclepedia_2088 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
711 Vesiclepedia_2831 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
712 Vesiclepedia_1029 26378940 Homo sapiens Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
713 Vesiclepedia_945 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
714 Vesiclepedia_1634 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
715 Vesiclepedia_3211 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
716 Vesiclepedia_3295 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
717 Vesiclepedia_2272 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma Protein Filtration
Size exclusion chromatography
Centrifugal ultrafiltration
Small extracellular vesicles Small EVs
718 Vesiclepedia_3338 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells Protein
miRNA
Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Small extracellular vesicles Small EVs
719 Vesiclepedia_2170 29643357 Staphylococcus aureus Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform Staphylococcus aureus Protein Filtration
Tangential flow filtration
OptiPrep density gradient centrifugation
Ultracentrifugation
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
720 Vesiclepedia_3099 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
721 Vesiclepedia_2485 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
722 Vesiclepedia_3542 33692304 Homo sapiens Use of Liquid Biopsy to Detect PIK3CA Mutation in Metastatic Breast Cancer Plasma dsDNA Exosome Isolation Kit Extracellular Vesicles EVs
723 Vesiclepedia_3174 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
724 Vesiclepedia_3266 34654817 Rattus norvegicus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Hippocampal neuronal cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
725 Vesiclepedia_2534 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein Centrifugation Extracellular vesicles Large EVs
726 Vesiclepedia_2531 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein Centrifugation Extracellular vesicles Large EVs
727 Vesiclepedia_2356 36708245 Homo sapiens Faeces-derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases Faeces Protein
Lipid
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
728 Vesiclepedia_2292 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Breast cancer cells Protein Polyethylene glycol-based precipitation
Centrifugation
Dialysis
Extracellular vesicles Small EVs
729 Vesiclepedia_3044 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts Protein Centrifugation
Polyethylene glycol-based precipitation
Extracellular vesicles EVs
730 Vesiclepedia_2076 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
731 Vesiclepedia_751 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles EVs
732 Vesiclepedia_2161 34140472 Ixodes scapularis Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Ixodes scapularis Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
733 Vesiclepedia_1043 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Extracellular vesicles EVs
734 Vesiclepedia_2513 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma Protein exoEasy Maxi Kit Extracellular vesicles EVs
735 Vesiclepedia_3172 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
736 Vesiclepedia_1207 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultrafiltration
Size exclusion chromatography
Extracellular vesicles EVs
737 Vesiclepedia_579 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
738 Vesiclepedia_3210 34957415 Mus musculus Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
739 Vesiclepedia_2679 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells Protein
Lipid
Metabolite
Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
740 Vesiclepedia_574 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
741 Vesiclepedia_1638 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
742 Vesiclepedia_2062 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
743 Vesiclepedia_2362 36748335 Homo sapiens Hypoxia promotes EV secretion by impairing lysosomal homeostasis in HNSCC through negative regulation of ATP6V1A by HIF-1α Oral cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
744 Vesiclepedia_2261 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
745 Vesiclepedia_2804 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
746 Vesiclepedia_2925 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
747 Vesiclepedia_3201 36754903 Mus musculus An extracellular vesicular mutant KRAS-associated protein complex promotes lung inflammation and tumor growth Lung epithelial cells Protein Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Extracellular vesicles Small EVs
748 Vesiclepedia_3223 32111843 Homo sapiens A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA Breast cancer cells Protein Differential centrifugation
Tangential flow filtration
Filtration
Size exclusion chromatography
Extracellular vesicles Small EVs
749 Vesiclepedia_2267 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma Protein Filtration
Size exclusion chromatography
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
750 Vesiclepedia_1614 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Centrifugal ultrafiltration
Immunoaffinity capture
Extracellular vesicles EVs
751 Vesiclepedia_1416 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
752 Vesiclepedia_3585 36591510 Homo sapiens Detection of circulating KRAS mutant DNA in extracellular vesicles using droplet digital PCR in patients with colon cancer Plasma dsDNA-mutated Differential centrifugation
Ultracentrifugation
Extracellular Vesicles EVs
753 Vesiclepedia_3488 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid Protein Differential centrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
754 Vesiclepedia_3104 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
755 Vesiclepedia_3230 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
756 Vesiclepedia_598 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
757 Vesiclepedia_1502 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum Protein
miRNA
ExoQuick Kit Extracellular vesicles Small EVs
758 Vesiclepedia_566 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (Igg1 PD)
Extracellular vesicles EVs
759 Vesiclepedia_2022 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells Protein Differential centrifugation Medium extracellular vesicles Large EVs
760 Vesiclepedia_1382 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
761 Vesiclepedia_3290 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
762 Vesiclepedia_2929 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
763 Vesiclepedia_2553 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
764 Vesiclepedia_3491 31278254 Mus musculus Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
765 Vesiclepedia_3213 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
766 Vesiclepedia_1932 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
767 Vesiclepedia_1710 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons Protein Differential centrifugation
Ultracentrifugation
Size exclusion chromatography
Extracellular vesicles EVs
768 Vesiclepedia_2122 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
769 Vesiclepedia_1850 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma Protein Centrifugation
Filtration
Exo-spin midi
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
770 Vesiclepedia_3335 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Small extracellular vesicles Small EVs
771 Vesiclepedia_1902 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
772 Vesiclepedia_1920 36303008 Homo sapiens A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples Glioma cells Protein Filtration
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
773 Vesiclepedia_1187 28326167 Homo sapiens Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment. Urine Protein Hydrostatic filtration dialysis
Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
774 Vesiclepedia_2414 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
775 Vesiclepedia_3386 31732668 Homo sapiens Label-free visualization and characterization of extracellular vesicles in breast cancer Mammary epithelial cells Metabolite - Extracellular vesicles Small EVs
776 Vesiclepedia_1189 28326167 Homo sapiens Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment. Urine Protein Hydrostatic filtration dialysis
Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
777 Vesiclepedia_1193 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
778 Vesiclepedia_1613 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Centrifugal ultrafiltration
Immunoaffinity capture
Extracellular vesicles EVs
779 Vesiclepedia_2578 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
780 Vesiclepedia_1035 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
Exo-spin Extracellular vesicles EVs
781 Vesiclepedia_2738 35545056 Homo sapiens MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
782 Vesiclepedia_2700 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
783 Vesiclepedia_3254 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
784 Vesiclepedia_1504 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum Protein Centrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
785 Vesiclepedia_2701 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
786 Vesiclepedia_3559 25086355 Rattus norvegicus Oncogenic ras-driven cancer cell vesiculation leads to emission of double-stranded DNA capable of interacting with target cells Epithelial cells dsDNA Filtration
Ultracentrifugation
Extracellular vesicles EVs
787 Vesiclepedia_2377 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
788 Vesiclepedia_2830 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
789 Vesiclepedia_1950 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
790 Vesiclepedia_3191 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
791 Vesiclepedia_2522 34315885 Mus musculus Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Kidney epithelial cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
792 Vesiclepedia_1746 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
793 Vesiclepedia_3370 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colon cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Small extracellular vesicles Small EVs
794 Vesiclepedia_2055 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
795 Vesiclepedia_2116 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient centrifugation
Small extracellular vesicles Small EVs
796 Vesiclepedia_2045 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
797 Vesiclepedia_2502 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells Protein ExoQuick Kit Extracellular vesicles EVs
798 Vesiclepedia_3520 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma Protein Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
799 Vesiclepedia_2540 34293122 Mus musculus Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein
Lipid
Centrifugation Extracellular vesicles Large EVs
800 Vesiclepedia_2784 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone miRNA ExoQuick Kit Extracellular vesicles Small EVs
801 Vesiclepedia_960 26047123 Bos taurus Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Filtration
Extracellular vesicles EVs
802 Vesiclepedia_2533 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein Centrifugation Extracellular vesicles Large EVs
803 Vesiclepedia_2537 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein Centrifugation Extracellular vesicles Large EVs
804 Vesiclepedia_2944 35106941 Cricetulus griseus K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Ovarian epithelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
805 Vesiclepedia_2138 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Serum Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
806 Vesiclepedia_2935 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
807 Vesiclepedia_1974 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
808 Vesiclepedia_2781 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone Protein Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
809 Vesiclepedia_1884 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
810 Vesiclepedia_1743 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
811 Vesiclepedia_3554 33375577 Homo sapiens Comparison of Circulating Tumour DNA and Extracellular Vesicle DNA by Low-Pass Whole-Genome Sequencing Reveals Molecular Drivers of Disease in a Breast Cancer Patient Plasma dsDNA Ultracentrifugation Extracellular Vesicles EVs
812 Vesiclepedia_3440 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
813 Vesiclepedia_606 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
814 Vesiclepedia_2873 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
815 Vesiclepedia_2381 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
816 Vesiclepedia_1861 35931686 Homo sapiens Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression Chondrocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
817 Vesiclepedia_2865 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Melanoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
818 Vesiclepedia_2857 33579909 Mus musculus Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
819 Vesiclepedia_2015 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells Protein Centrifugation Large extracellular vesicles Large EVs
820 Vesiclepedia_997 24392111 Mus musculus Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk? Murine myotubues Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
821 Vesiclepedia_1480 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
822 Vesiclepedia_3258 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
823 Vesiclepedia_3415 33391636 Homo sapiens Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus Colorectal cancer cells Protein Differential centrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
824 Vesiclepedia_3494 31278254 Mus musculus Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
825 Vesiclepedia_3332 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Lung cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Small extracellular vesicles Small EVs
826 Vesiclepedia_3088 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
827 Vesiclepedia_3516 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma Protein Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
828 Vesiclepedia_2187 33792189 Mus musculus A novel role for milk fat globule-EGF factor 8 protein (MFGE8) in the mediation of mouse sperm-extracellular vesicle interactions Epididymal epithelial cells Protein Filtration
Tangential flow filtration
OptiPrep density gradient centrifugation
Ultracentrifugation
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
829 Vesiclepedia_851 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
830 Vesiclepedia_3531 30936474 Homo sapiens Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells Macrophage Protein
lncRNA
Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
831 Vesiclepedia_868 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles EVs
832 Vesiclepedia_1804 35917363 Homo sapiens CD9 mediates the uptake of extracellular vesicles from cancer-associated fibroblasts that promote pancreatic cancer cell aggressiveness Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
833 Vesiclepedia_2026 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Osteosarcoma cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
834 Vesiclepedia_1640 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
835 Vesiclepedia_951 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
836 Vesiclepedia_3204 34596354 Homo sapiens Extracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p Mesenchymal stem cells Protein Tangential flow filtration Extracellular vesicles Small EVs
837 Vesiclepedia_2539 34293122 Mus musculus Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein Centrifugation Extracellular vesicles Large EVs
838 Vesiclepedia_858 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
839 Vesiclepedia_2827 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
840 Vesiclepedia_3304 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
841 Vesiclepedia_634 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Prostate cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
842 Vesiclepedia_1419 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
843 Vesiclepedia_3323 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
844 Vesiclepedia_3330 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
845 Vesiclepedia_1179 29854963 Homo sapiens Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. Urine miRNA qEV size-exclusion column Extracellular vesicles EVs
846 Vesiclepedia_944 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
847 Vesiclepedia_2370 36759608 Homo sapiens Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo Adipocytes Protein Differential centrifugation
Ultracentrifugation
Size exclusion chromatography
Extracellular vesicles Small EVs
848 Vesiclepedia_2569 35260554 Homo sapiens Tumor-derived extracellular vesicles shuttle c-Myc to promote gastric cancer growth and metastasis via the KCNQ1OT1/miR-556-3p/CLIC1 axis Gastric cancer cells Protein Centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
849 Vesiclepedia_2061 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
850 Vesiclepedia_3475 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Cystic fluid Protein Differential centrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
851 Vesiclepedia_1776 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid Protein Differential centrifugation Extracellular vesicles Large EVs
852 Vesiclepedia_2690 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells Protein EVtrap Extracellular vesicles Small EVs
853 Vesiclepedia_1848 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma Protein Centrifugation
Filtration
Exo-spin midi
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
854 Vesiclepedia_3308 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
855 Vesiclepedia_3216 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
856 Vesiclepedia_2135 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Serum Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
857 Vesiclepedia_2507 34322206 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells Protein MagCapture Exosome Isolation Kit PS Extracellular vesicles EVs
858 Vesiclepedia_2955 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes Protein Differential centrifugation Extracellular vesicles Large EVs
859 Vesiclepedia_946 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
860 Vesiclepedia_2227 32494663 Homo sapiens miR-26a regulates extracellular vesicle secretion from prostate cancer cells via targeting SHC4, PFDN4, and CHORDC1 Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
861 Vesiclepedia_1561 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells Protein Centrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
862 Vesiclepedia_890 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
863 Vesiclepedia_1708 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons Protein Differential centrifugation
Ultracentrifugation
Size exclusion chromatography
Extracellular vesicles EVs
864 Vesiclepedia_3241 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
865 Vesiclepedia_1055 30035390 Mus musculus Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Mouse embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
866 Vesiclepedia_3551 34158841 Homo sapiens Plasma-derived DNA containing-extracellular vesicles induce STING-mediated proinflammatory responses in dermatomyositis Plasma dsDNA Differential centrifugation
Ultracentrifugation
Exosome Isolation Kit
Extracellular Vesicles EVs
867 Vesiclepedia_1408 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
868 Vesiclepedia_1732 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
869 Vesiclepedia_1066 29963299 Homo sapiens Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography. Synovial fluid Protein Size exclusion chromatography Extracellular vesicles EVs
870 Vesiclepedia_595 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
871 Vesiclepedia_622 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
872 Vesiclepedia_2519 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma Protein OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles EVs
873 Vesiclepedia_1782 35932288 Homo sapiens Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
874 Vesiclepedia_613 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
875 Vesiclepedia_1639 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
876 Vesiclepedia_2200 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Size exclusion chromatography
Extracellular vesicles Small EVs
877 Vesiclepedia_3547 34453041 Homo sapiens Extracellular vesicles package dsDNA to aggravate Crohn's disease by activating the STING pathway Plasma dsDNA Size exclusion chromatography Extracellular Vesicles EVs
878 Vesiclepedia_1716 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
879 Vesiclepedia_1722 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
880 Vesiclepedia_3565 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Embroyonic fibroblasts mtDNA Ultracentrifugation Extracellular vesicles EVs
881 Vesiclepedia_2391 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
882 Vesiclepedia_2476 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
883 Vesiclepedia_1773 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid Protein Differential centrifugation Extracellular vesicles Large EVs
884 Vesiclepedia_2549 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
885 Vesiclepedia_1994 34188787 Mus musculus Arrdc4-dependent extracellular vesicle biogenesis is required for sperm maturation Epididymal epithelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
886 Vesiclepedia_1799 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells miRNA Size exclusion chromatography Extracellular vesicles Small EVs
887 Vesiclepedia_2021 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells Protein Centrifugation Large extracellular vesicles Large EVs
888 Vesiclepedia_1843 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Normal colon fibroblasts Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
889 Vesiclepedia_1781 35932288 Homo sapiens Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
890 Vesiclepedia_1303 - Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
891 Vesiclepedia_1714 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
892 Vesiclepedia_1172 29881354 Rattus norvegicus Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. Serum Protein
miRNA
ExoQuick Extracellular vesicles EVs
893 Vesiclepedia_2008 35979935 Homo sapiens Serum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients Serum Protein
Lipid
Differential centrifugation Extracellular vesicles EVs
894 Vesiclepedia_510 23521563 Homo sapiens First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Ewing's sarcoma cells mRNA - Exosomes/Extracellular vesicles EVs
895 Vesiclepedia_1795 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells miRNA Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
896 Vesiclepedia_2678 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells Protein
Lipid
Metabolite
Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
897 Vesiclepedia_1385 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
898 Vesiclepedia_587 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
899 Vesiclepedia_1791 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells miRNA Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
900 Vesiclepedia_1631 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells Protein
Lipid
Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
901 Vesiclepedia_3435 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
902 Vesiclepedia_1023 22327366 Homo sapiens Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Vascular endothelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
903 Vesiclepedia_2073 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
904 Vesiclepedia_1056 30035390 Mus musculus Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Mouse embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
905 Vesiclepedia_1725 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
906 Vesiclepedia_3569 25133686 Homo sapiens Transferred BCR/ABL DNA from K562 extracellular vesicles causes chronic myeloid leukemia in immunodeficient mice Myelogenous leukemia cells Genomic DNA Ultracentrifugation Extracellular vesicles EVs
907 Vesiclepedia_1704 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons Protein Differential centrifugation
Ultracentrifugation
Size exclusion chromatography
Extracellular vesicles EVs
908 Vesiclepedia_3576 33915956 Homo sapiens Exosomes from Plasma of Neuroblastoma Patients Contain Doublestranded DNA Reflecting the Mutational Status of Parental Tumor Cells Plasma dsDNA-mutated Exo-RNeasy Kit Extracellular Vesicles EVs
909 Vesiclepedia_2318 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Plasma Protein
small RNA
ExoQuick Kit Extracellular vesicles/Exosomes EVs
910 Vesiclepedia_1600 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Centrifugal ultrafiltration
Immunoaffinity capture
Extracellular vesicles EVs
911 Vesiclepedia_1312 - Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
912 Vesiclepedia_2562 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
913 Vesiclepedia_2312 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles B cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
914 Vesiclepedia_1993 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
915 Vesiclepedia_633 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Prostate cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
916 Vesiclepedia_2579 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
917 Vesiclepedia_3166 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
918 Vesiclepedia_1478 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
919 Vesiclepedia_2590 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
920 Vesiclepedia_2740 35513391 Homo sapiens Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1 Posterior longitudinal ligament miRNA Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
921 Vesiclepedia_1735 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
922 Vesiclepedia_2557 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
923 Vesiclepedia_2874 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
924 Vesiclepedia_1030 26378940 Homo sapiens Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
925 Vesiclepedia_839 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
926 Vesiclepedia_2159 34140472 Dermacentor andersoni Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Dermacentor andersoni Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
927 Vesiclepedia_3171 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
928 Vesiclepedia_1128 23954818 Homo sapiens Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Squamous carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
929 Vesiclepedia_2031 36123372 Homo sapiens Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells Umbilical vein endothelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
930 Vesiclepedia_1995 34188787 Mus musculus Arrdc4-dependent extracellular vesicle biogenesis is required for sperm maturation Epididymal epithelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
931 Vesiclepedia_3093 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
932 Vesiclepedia_2589 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
933 Vesiclepedia_3558 28966872 Homo sapiens Rapid magnetic isolation of extracellular vesicles via lipid-based nanoprobes Breast cancer cells dsDNA Differential centrifugation
Filtration
Ultracentrifugation
Nanoscale extracellular vesicles EVs
934 Vesiclepedia_2271 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma Protein Filtration
Size exclusion chromatography
Centrifugal ultrafiltration
Small extracellular vesicles Small EVs
935 Vesiclepedia_3089 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
936 Vesiclepedia_601 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
937 Vesiclepedia_3219 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
938 Vesiclepedia_619 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
939 Vesiclepedia_617 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
940 Vesiclepedia_2266 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
941 Vesiclepedia_1767 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid Protein Differential centrifugation Extracellular vesicles Large EVs
942 Vesiclepedia_2164 34140472 Ixodes scapularis Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Ixodes scapularis Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
943 Vesiclepedia_842 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
944 Vesiclepedia_509 23521563 Homo sapiens First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Ewing's sarcoma cells mRNA - Exosomes/Extracellular vesicles EVs
945 Vesiclepedia_2412 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
946 Vesiclepedia_2541 34293122 Mus musculus Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein
Lipid
Centrifugation Extracellular vesicles Large EVs
947 Vesiclepedia_1406 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells Protein Differential centrifugation
Tangential flow filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
948 Vesiclepedia_2274 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma Protein Filtration
Size exclusion chromatography
Ion exchange adsorption
Centrifugation
Centrifugal ultrafiltration
Small extracellular vesicles Small EVs
949 Vesiclepedia_1225 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma Protein Exo-spin Extracellular vesicles EVs
950 Vesiclepedia_3544 31232418 Homo sapiens Enrichment of extracellular vesicles with lipid nanoprobe functionalized nanostructured silica Plasma dsDNA Lipid nanoprobe functionalized nanostructured silica platform Nanoscale extracellular Vesicles EVs
951 Vesiclepedia_1853 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma Protein Centrifugation
Filtration
Exo-spin midi
Centrifugal ultrafiltration
Extracellular vesicles Small EVs
952 Vesiclepedia_1562 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells Protein Centrifugation
Centrifugal ultrafiltration
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
953 Vesiclepedia_1608 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Centrifugal ultrafiltration
Immunoaffinity capture
Extracellular vesicles EVs
954 Vesiclepedia_2302 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Monocytes miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
955 Vesiclepedia_1036 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
Exo-spin Extracellular vesicles EVs
956 Vesiclepedia_3267 34654817 Rattus norvegicus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Hippocampal neuronal cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
957 Vesiclepedia_2608 32383290 Ovis aries Quantitative Proteomic Analysis of Seminal Plasma, Sperm Membrane Proteins, and Seminal Extracellular Vesicles Suggests Vesicular Mechanisms Aid in the Removal and Addition of Proteins to the Ram Sperm Membrane Seminal plasma Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
958 Vesiclepedia_2512 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma Protein ExoQuick Kit Extracellular vesicles EVs
959 Vesiclepedia_2477 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
960 Vesiclepedia_2397 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
961 Vesiclepedia_1208 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultrafiltration
Size exclusion chromatography
Extracellular vesicles EVs
962 Vesiclepedia_841 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
963 Vesiclepedia_1520 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Mast cells miRNA ExoQuick Kit Extracellular vesicles Small EVs
964 Vesiclepedia_2938 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
965 Vesiclepedia_2481 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
966 Vesiclepedia_2801 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
967 Vesiclepedia_3539 33915956 Homo sapiens Exosomes from Plasma of Neuroblastoma Patients Contain Doublestranded DNA Reflecting the Mutational Status of Parental Tumor Cells Plasma dsDNA Exo-RNeasy Kit Extracellular Vesicles EVs
968 Vesiclepedia_1374 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Total Exosome Isolation Reagent
Extracellular vesicles Small EVs
969 Vesiclepedia_2866 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
970 Vesiclepedia_3447 32341770 Mus musculus DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Plasma Protein Differential centrifugation
ExoQuick Kit
Extracellular vesicles Small EVs
971 Vesiclepedia_2729 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
972 Vesiclepedia_1721 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
973 Vesiclepedia_1060 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells Protein Filtration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles EVs
974 Vesiclepedia_2858 33579909 Mus musculus Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
975 Vesiclepedia_3556 36591510 Homo sapiens Detection of circulating KRAS mutant DNA in extracellular vesicles using droplet digital PCR in patients with colon cancer Plasma dsDNA Differential centrifugation
Ultracentrifugation
Extracellular Vesicles EVs
976 Vesiclepedia_1038 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
miRCURY Exosome Isolation Kit Extracellular vesicles EVs
977 Vesiclepedia_2405 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
978 Vesiclepedia_3244 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
979 Vesiclepedia_2051 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
980 Vesiclepedia_1771 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid Protein Differential centrifugation Extracellular vesicles Large EVs
981 Vesiclepedia_2900 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Gastric cancer cells Protein Filtration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
982 Vesiclepedia_2895 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells Protein Filtration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
983 Vesiclepedia_2890 28928431 Mus musculus Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90 Lung cancer cells Protein Centrifugal ultrafiltration
ExoQuick Kit
Extracellular vesicles EVs
984 Vesiclepedia_930 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Bladder cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
985 Vesiclepedia_1586 33692129 Macaca fascicularis Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates Mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Small extracellular vesicles Small EVs
986 Vesiclepedia_1471 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
987 Vesiclepedia_2010 36417867 Homo sapiens Extracellular vesicles carrying HIV-1 Nef induce long-term hyperreactivity of myeloid cells Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
988 Vesiclepedia_1984 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
989 Vesiclepedia_3498 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets Protein Differential centrifugation Extracellular vesicles EVs
990 Vesiclepedia_2102 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient centrifugation
Small extracellular vesicles Small EVs
991 Vesiclepedia_2737 35545056 Homo sapiens MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
992 Vesiclepedia_2828 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
993 Vesiclepedia_2137 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Macrophage Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
994 Vesiclepedia_3527 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma Protein Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
995 Vesiclepedia_1775 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid Protein Differential centrifugation Extracellular vesicles Large EVs
996 Vesiclepedia_1574 33785738 Homo sapiens Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Osteosarcoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
997 Vesiclepedia_3194 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
998 Vesiclepedia_2907 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells Protein Filtration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
999 Vesiclepedia_1983 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1000 Vesiclepedia_1414 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
1001 Vesiclepedia_1306 - Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
1002 Vesiclepedia_1802 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells miRNA Size exclusion chromatography Extracellular vesicles Small EVs
1003 Vesiclepedia_748 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles EVs
1004 Vesiclepedia_2145 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Macrophage Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1005 Vesiclepedia_2142 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Serum Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1006 Vesiclepedia_483 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Epimastigotes Protein - Exosomes/Extracellular vesicles/Ectosomes EVs
1007 Vesiclepedia_2160 34140472 Ixodes scapularis Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Salivary glands Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1008 Vesiclepedia_1588 33692129 Macaca fascicularis Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates Mesenchymal stem cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
1009 Vesiclepedia_2838 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1010 Vesiclepedia_1751 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
OptiPrep density gradient centrifugation
Extracellular vesicles EVs
1011 Vesiclepedia_2072 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
1012 Vesiclepedia_2096 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
1013 Vesiclepedia_614 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
1014 Vesiclepedia_1040 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Extracellular vesicles EVs
1015 Vesiclepedia_2923 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
1016 Vesiclepedia_2940 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
1017 Vesiclepedia_3097 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
1018 Vesiclepedia_2542 34293122 Mus musculus Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets Protein
Lipid
Centrifugation Extracellular vesicles Large EVs
1019 Vesiclepedia_2221 34596356 Homo sapiens Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Primary prostate stromal cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1020 Vesiclepedia_612 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
1021 Vesiclepedia_2373 35087866 Rattus norvegicus Exercise-Induced Extracellular Vesicles Delay the Progression of Prostate Cancer Plasma RNA Size exclusion chromatography
Filtration
Extracellular vesicles Small EVs
1022 Vesiclepedia_2264 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
1023 Vesiclepedia_2215 35953855 Bos taurus Milk-derived small extracellular vesicles: nanomaterials to promote bone formation Bovine milk Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1024 Vesiclepedia_553 24009898 Mus musculus Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. Cardiomyocytes mRNA - Exosomes/Extracellular vesicles EVs
1025 Vesiclepedia_3301 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
1026 Vesiclepedia_2869 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
1027 Vesiclepedia_2846 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Extracellular vesicles Small EVs
1028 Vesiclepedia_1603 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Differential centrifugation Extracellular vesicles Large EVs
1029 Vesiclepedia_1619 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1030 Vesiclepedia_2554 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1031 Vesiclepedia_3545 36125881 Homo sapiens Cell-free DNA topology depends on its subcellular and cellular origins in cancer Plasma mtDNA - Extracellular Vesicles EVs
1032 Vesiclepedia_3470 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ovarian cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
1033 Vesiclepedia_2387 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma Protein Size exclusion chromatography Extracellular vesicles Small EVs
1034 Vesiclepedia_3040 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts Protein Centrifugation
Polyethylene glycol-based precipitation
Extracellular vesicles EVs
1035 Vesiclepedia_2065 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
1036 Vesiclepedia_3432 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells Protein Centrifugal ultrafiltration
Size exclusion chromatography
Extracellular vesicles Small EVs
1037 Vesiclepedia_2069 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
1038 Vesiclepedia_2331 36635419 Homo sapiens Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy Fibroblasts Protein
mRNA
Centrifugal ultrafiltration
Immunoaffinity capture
Extracellular vesicles EVs
1039 Vesiclepedia_1881 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1040 Vesiclepedia_1778 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid Protein Differential centrifugation Extracellular vesicles Large EVs
1041 Vesiclepedia_1951 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
1042 Vesiclepedia_1895 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1043 Vesiclepedia_570 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (CD63 PD)
Extracellular vesicles EVs
1044 Vesiclepedia_1760 35918900 Homo sapiens Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1045 Vesiclepedia_2192 35229476 Lactococcus lactis Extracellular vesicle formation in Lactococcus lactis is stimulated by prophage-encoded holin-lysin system Lactococcus lactis Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1046 Vesiclepedia_1518 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum miRNA ExoQuick Kit Extracellular vesicles Small EVs
1047 Vesiclepedia_2306 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Monocytes miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
1048 Vesiclepedia_2870 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
1049 Vesiclepedia_3238 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
1050 Vesiclepedia_844 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
1051 Vesiclepedia_3297 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
1052 Vesiclepedia_2937 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
1053 Vesiclepedia_2092 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells Protein Differential centrifugation Large extracellular vesicles Large EVs
1054 Vesiclepedia_1929 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Small extracellular vesicles Small EVs
1055 Vesiclepedia_1494 33991177 Homo sapiens Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Gastric cancer cells Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
1056 Vesiclepedia_618 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles EVs
1057 Vesiclepedia_2201 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Size exclusion chromatography
Extracellular vesicles Small EVs
1058 Vesiclepedia_1371 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Total Exosome Isolation Reagent
Extracellular vesicles Small EVs
1059 Vesiclepedia_2265 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma Protein Differential centrifugation
Ultracentrifugation
Small extracellular vesicles Small EVs
1060 Vesiclepedia_2433 29320704 Homo sapiens Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Plasma Protein Centrifugation Extracellular vesicles EVs
1061 Vesiclepedia_2896 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells Protein Filtration
Centrifugal ultrafiltration
ExoQuick Kit
Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1062 Vesiclepedia_3173 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles Small EVs
1063 Vesiclepedia_1728 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma Protein Centrifugal filtration
Size exclusion chromatography
Extracellular vesicles EVs
1064 Vesiclepedia_2012 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells Protein Centrifugation Large extracellular vesicles Large EVs
1065 Vesiclepedia_487 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles EVs
1066 Vesiclepedia_852 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles EVs
1067 Vesiclepedia_2202 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk Protein Differential centrifugation
OptiPrep density gradient centrifugation
Size exclusion chromatography
Extracellular vesicles Small EVs
1068 Vesiclepedia_2112 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Small extracellular vesicles Small EVs
1069 Vesiclepedia_2552 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
OptiPrep density gradient centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1070 Vesiclepedia_2565 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles Small EVs
1071 Vesiclepedia_2592 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Small extracellular vesicles<