Browse results for vesicle type: Exosomes |
Vesiclepedia ID | PubMed ID | Species | Experiment description | Sample | Identifications | Isolation methods | Vesicle type | MISEV | |
1 | Vesiclepedia_2745 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
2 | Vesiclepedia_510 | 23521563 | Homo sapiens | First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. | Ewing's sarcoma cells | mRNA | - | Exosomes/Extracellular vesicles | EVs |
3 | Vesiclepedia_11 | 12519789 | Homo sapiens | Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation. | B cells |
Protein Lipids |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
4 | Vesiclepedia_791 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
5 | Vesiclepedia_2640 | 35649370 | Homo sapiens | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Cervical cancer cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
6 | Vesiclepedia_93 | 20124479 | Rattus norvegicus | Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. | Pancreatic cancer cells |
Protein mRNA |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
7 | Vesiclepedia_6 | 11306949 | Mus musculus | Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes. | Mast cells | Protein | - | Exosomes | EVs |
8 | Vesiclepedia_1356 | 32438511 | Homo sapiens | Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion | Colorectal cancer cells | Protein | Differential centrifugation Filtration OptiPrep density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
9 | Vesiclepedia_1217 | 27872147 | Rattus norvegicus | Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. | Islets | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
10 | Vesiclepedia_923 | 25483805 | Homo sapiens | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties | Embryonic kidney cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
11 | Vesiclepedia_1330 | 33431899 | Mus musculus | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Faeces | Lipid | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
12 | Vesiclepedia_2972 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
13 | Vesiclepedia_693 | 28170197 | Homo sapiens | Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 | Bone marrow mesenchymal stem cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
14 | Vesiclepedia_795 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
15 | Vesiclepedia_3073 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
16 | Vesiclepedia_1935 | 36103526 | Homo sapiens | Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases | Hepatic stellate cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
17 | Vesiclepedia_3160 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
18 | Vesiclepedia_216 | 21293856 | Homo sapiens | Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC | Breast cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
19 | Vesiclepedia_3410 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
20 | Vesiclepedia_84 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Lung cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
21 | Vesiclepedia_2257 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
22 | Vesiclepedia_813 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
23 | Vesiclepedia_2318 | 31762962 | Homo sapiens | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers | Plasma |
Protein small RNA |
ExoQuick Kit | Extracellular vesicles/Exosomes | EVs |
24 | Vesiclepedia_2347 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
25 | Vesiclepedia_125 | 21059916 | Homo sapiens | Human tumor virus utilizes exosomes for intercellular communication. | Nasopharyngeal carcinoma cells | Protein | Differential centrifugation | Exosomes | EVs |
26 | Vesiclepedia_31 | 10572093 | Homo sapiens | Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. | Platelets | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
27 | Vesiclepedia_1086 | 25065644 | Homo sapiens | Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. | Duodenal cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration |
Exosomes | EVs |
28 | Vesiclepedia_765 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
29 | Vesiclepedia_1105 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
30 | Vesiclepedia_1569 | 33738083 | Homo sapiens | Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
31 | Vesiclepedia_399 | 19530224 | Homo sapiens | Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. | Keratinocytes | Protein | - | Exosomes | EVs |
32 | Vesiclepedia_1546 | 33767144 | Homo sapiens | Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells | Cervical cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
33 | Vesiclepedia_2456 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
34 | Vesiclepedia_508 | 23511837 | Homo sapiens | Differential protein profiling of renal cell carcinoma urinary exosomes. | Urine | Protein | - | Exosomes/Nanovesicles | EVs |
35 | Vesiclepedia_1113 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
36 | Vesiclepedia_1250 | 24939845 | Homo sapiens | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. | Leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
37 | Vesiclepedia_3079 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
38 | Vesiclepedia_3050 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
39 | Vesiclepedia_1342 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | Muscle | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
40 | Vesiclepedia_1159 | 20409149 | Homo sapiens | Transdifferentiated circulating monocytes release exosomes containing 14-3-3 proteins with matrix metalloproteinase-1 stimulating effect for dermal fibroblasts. | Keratinocytes | Protein | Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
41 | Vesiclepedia_2651 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
42 | Vesiclepedia_1154 | 22057275 | Homo sapiens | Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. | Cerebrospinal fluid | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
43 | Vesiclepedia_1069 | 29937354 | Homo sapiens | Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. | Glioblastoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
44 | Vesiclepedia_678 | 29951053 | Mus musculus | Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. | Myeloid-derived suppressor cells | Protein | Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
45 | Vesiclepedia_1366 | 32132711 | Mus musculus | Decoy exosomes provide protection against bacterial toxins | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
46 | Vesiclepedia_139 | 22723089 | Homo sapiens | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. | Prostate cancer cells | Protein | Sucrose density gradient | Exosomes | EVs |
47 | Vesiclepedia_1111 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
48 | Vesiclepedia_2978 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Iodixanol density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
49 | Vesiclepedia_1661 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Pancreatic duct epithelial cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
50 | Vesiclepedia_1436 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
51 | Vesiclepedia_1101 | 24513287 | Mus musculus | Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. | Serum | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
52 | Vesiclepedia_32 | 18452139 | Homo sapiens | Primary human keratinocytes externalize stratifin protein via exosomes. | Keratinocytes | Protein | Differential centrifugation Sucrose density gradient Diafiltration |
Exosomes | EVs |
53 | Vesiclepedia_3051 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Plasma | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
54 | Vesiclepedia_2471 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
55 | Vesiclepedia_778 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
56 | Vesiclepedia_1100 | 24513287 | Mus musculus | Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. | adipocytes | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
57 | Vesiclepedia_83 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Lung cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
58 | Vesiclepedia_770 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
59 | Vesiclepedia_3045 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Plasma |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
60 | Vesiclepedia_450 | 22451062 | Homo sapiens | A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: application to RCC urinary exosomes. | Urine | Lipids | - | Exosomes | EVs |
61 | Vesiclepedia_119 | 21362503 | Homo sapiens | Protein profile of exosomes from trabecular meshwork cells. | Urine | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
62 | Vesiclepedia_2751 | 35173168 | Homo sapiens | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
63 | Vesiclepedia_2966 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
64 | Vesiclepedia_918 | 28687758 | Sus scrofa | Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers | Polarised retinal pigmented epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
65 | Vesiclepedia_2776 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
66 | Vesiclepedia_484 | 23214914 | Trypanosoma cruzi | Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. | Epimastigotes | Protein | - | Exosomes/Extracellular vesicles/Ectosomes | EVs |
67 | Vesiclepedia_1248 | 24939845 | Homo sapiens | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. | Leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
68 | Vesiclepedia_802 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
69 | Vesiclepedia_3062 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
70 | Vesiclepedia_1688 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Pancreatic cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
71 | Vesiclepedia_899 | 26100252 | Homo sapiens | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts | Chronic lymphocytic leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
72 | Vesiclepedia_2621 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
73 | Vesiclepedia_2461 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
74 | Vesiclepedia_471 | 23035643 | Drosophila melanogaster | Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes. | Drosophila S2 cells | Protein | - | Exosomes | EVs |
75 | Vesiclepedia_2344 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
76 | Vesiclepedia_786 | 29953723 | Oncorhynchus tshawytscha | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
77 | Vesiclepedia_1696 | 34108659 | Mus musculus | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Embryonic fibroblasts | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
78 | Vesiclepedia_1087 | 25065644 | Homo sapiens | Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. | Duodenal cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration |
Exosomes | EVs |
79 | Vesiclepedia_1997 | 34112803 | Mus musculus | Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Centrifugal ultrafiltration |
Exosomes | Small EVs |
80 | Vesiclepedia_3052 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Plasma | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
81 | Vesiclepedia_2693 | 35210436 | Homo sapiens | M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway | Macrophage |
Protein mRNA |
Total Exosome Isolation Reagent | Exosomes | Small EVs |
82 | Vesiclepedia_130 | 18309083 | Mus musculus | Ceramide triggers budding of exosome vesicles into multivesicular endosomes | Oligodendrocytes |
Protein Lipids |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
83 | Vesiclepedia_3116 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Brain | Protein | Differential centrifugation Filtration Sucrose density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
84 | Vesiclepedia_461 | 22848702 | Homo sapiens | Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles. | Medulloblastoma cells | Protein | - | Exosomes/Membrane vesicles/Extracellular vesicles | EVs |
85 | Vesiclepedia_924 | 25483805 | Homo sapiens | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties | Embryonic kidney cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
86 | Vesiclepedia_57 | 17700640 | Homo sapiens | CD24 is a marker of exosomes secreted into urine and amniotic fluid. | Urine | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
87 | Vesiclepedia_2983 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
88 | Vesiclepedia_970 | 25844599 | Homo sapiens | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. | Serum | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
89 | Vesiclepedia_1334 | 33368224 | Homo sapiens | Colorectal cancer prompted adipose tissue browning and cancer cachexia through transferring exosomal miR-146b-5p | Colorectal cancer cells |
Protein mRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
90 | Vesiclepedia_720 | 26148937 | Homo sapiens | Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. | Cholangiocytes | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
91 | Vesiclepedia_1201 | 27780738 | Homo sapiens | Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. | Cerebrospinal fluid | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
92 | Vesiclepedia_1237 | 25421927 | Heligmosomoides polygyrus | Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. | Heligmosomoides polygyrus |
miRNA Protein |
Filtration Ultracentrifugation |
Exosomes | EVs |
93 | Vesiclepedia_925 | 25483805 | Homo sapiens | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties | Embryonic kidney cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
94 | Vesiclepedia_39 | 15210972 | Mus musculus | Cells release prions in association with exosomes. | Mov neuroglial cell | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
95 | Vesiclepedia_669 | 29953960 | Homo sapiens | Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. | Macrophage | Protein | Microfiltration Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
96 | Vesiclepedia_3083 | 33827783 | Mus musculus | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic duct epithelial cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
97 | Vesiclepedia_1692 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Pancreatic cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
98 | Vesiclepedia_719 | 26148937 | Homo sapiens | Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. | Cholangiocarcinoma cells | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
99 | Vesiclepedia_3118 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Brain | Protein | Differential centrifugation Filtration Sucrose density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
100 | Vesiclepedia_823 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
101 | Vesiclepedia_47 | 17641064 | Homo sapiens | Exosomes with immune modulatory features are present in human breast milk. | B cells | Protein | Differential centrifugation Filtration Sucrose density gradient |
Exosomes | EVs |
102 | Vesiclepedia_3251 | 34545097 | Homo sapiens | Exosome-mediated stable epigenetic repression of HIV-1 | Embryonic kidney cells |
Protein mRNA |
Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
103 | Vesiclepedia_1099 | 24513287 | Mus musculus | Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. | adipocytes | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
104 | Vesiclepedia_3074 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
105 | Vesiclepedia_3061 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
106 | Vesiclepedia_2336 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
107 | Vesiclepedia_1567 | 33523942 | Homo sapiens | Exosomal delivery of NF-κB inhibitor delays LPS-induced preterm birth and modulates fetal immune cell profile in mouse models | Embryonic kidney cells | Protein | Centrifugation Filtration Size exclusion chromatography |
Exosomes | Small EVs |
108 | Vesiclepedia_1221 | 27872147 | Rattus norvegicus | Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. | Insulinoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
109 | Vesiclepedia_3400 | 31054213 | Homo sapiens | Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma | Cholangiocarcinoma cells | Protein | Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
110 | Vesiclepedia_486 | 23230278 | Homo sapiens | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. | Colorectal cancer cells | Protein | - | Exosomes/Extracellular vesicles/Microvesicles | EVs |
111 | Vesiclepedia_509 | 23521563 | Homo sapiens | First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. | Ewing's sarcoma cells | mRNA | - | Exosomes/Extracellular vesicles | EVs |
112 | Vesiclepedia_1534 | 33589572 | Homo sapiens | Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis | Plasma |
Protein lncRNA |
Centrifugation ExoQuick Kit |
Exosomes | Small EVs |
113 | Vesiclepedia_552 | 24009898 | Mus musculus | Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. | Cardiomyocytes | mRNA | - | Exosomes/Extracellular vesicles | EVs |
114 | Vesiclepedia_2423 | 35939247 | Homo sapiens | Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
115 | Vesiclepedia_1529 | 33752173 | Homo sapiens | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression | Breast cancer cells | miRNA | Total Exosome Isolation Kit Centrifugation |
Exosomes | Small EVs |
116 | Vesiclepedia_2419 | 35939247 | Homo sapiens | Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
117 | Vesiclepedia_127 | 21828046 | Rattus norvegicus | Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation | Reticulocytes |
Protein Lipids |
Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
118 | Vesiclepedia_740 | 25157233 | Homo sapiens | Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. | Placenta choriocarcinoma cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
119 | Vesiclepedia_1267 | 24218614 | Homo sapiens | Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
120 | Vesiclepedia_413 | 20535238 | Rattus norvegicus | Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. | Urine | Protein | - | Exosomes | EVs |
121 | Vesiclepedia_511 | 23521563 | Homo sapiens | First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. | Ewing's sarcoma cells | mRNA | - | Exosomes/Extracellular vesicles | EVs |
122 | Vesiclepedia_2447 | 34489604 | Mus musculus | Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 | Hepatocytes | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
123 | Vesiclepedia_525 | 23658846 | Mus musculus | Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. | Macrophage | Protein | - | Exosomes | EVs |
124 | Vesiclepedia_3046 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Plasma |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
125 | Vesiclepedia_829 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
126 | Vesiclepedia_431 | 21595033 | Homo sapiens | Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. | Urine | Protein | - | Exosomes | EVs |
127 | Vesiclepedia_884 | 29955024 | Homo sapiens | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells | Myeloid leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
128 | Vesiclepedia_536 | 23818640 | Homo sapiens | Modulation of B-cell exosome proteins by gamma herpesvirus infection. | B cells | Protein | - | Exosomes/Microvesicles/Oncosomes/Microparticles | EVs |
129 | Vesiclepedia_65 | 19415654 | Homo sapiens | Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7. | Breast cancer cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
130 | Vesiclepedia_1657 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Foreskin fibroblasts |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
131 | Vesiclepedia_2999 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
132 | Vesiclepedia_237 | 21293856 | Homo sapiens | Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC | Melanoma cells | Protein | Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
133 | Vesiclepedia_3133 | 34500436 | Homo sapiens | MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
134 | Vesiclepedia_1053 | 29115712 | Mus musculus | Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
135 | Vesiclepedia_1161 | 22641613 | Homo sapiens | Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. | Urine | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
136 | Vesiclepedia_973 | 22808001 | Homo sapiens | Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. | Serum | Protein | Filtration ExoQuick |
Exosomes | EVs |
137 | Vesiclepedia_1922 | 36253358 | Mus musculus | Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM | Mesenchymal stem cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
138 | Vesiclepedia_1085 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
139 | Vesiclepedia_3567 | 28750687 | Homo sapiens | Extracellular vesicles from human liver stem cells restore argininosuccinate synthase deficiency | Liver stem cells | dsDNA | Differential centrifugation Ultracentrifugation |
Extracellular vesicles|Exosomes | EVs |
140 | Vesiclepedia_672 | 29953960 | Homo sapiens | Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. | Macrophage | Protein | Microfiltration Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
141 | Vesiclepedia_1537 | 33523480 | Homo sapiens | Human fibroblast-derived extracellular vesicles promote hair growth in cultured human hair follicles | Fibroblasts | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
142 | Vesiclepedia_2747 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
143 | Vesiclepedia_713 | 28811610 | Homo sapiens | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
144 | Vesiclepedia_798 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
145 | Vesiclepedia_3273 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
146 | Vesiclepedia_277 | 22030351 | Homo sapiens | Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways | Prostate cancer cells | Protein | Differential centrifugation | Exosomes | EVs |
147 | Vesiclepedia_2759 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Tangential flow filtration | Exosomes | Small EVs |
148 | Vesiclepedia_3132 | 34500436 | Homo sapiens | MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
149 | Vesiclepedia_2321 | 31762962 | Homo sapiens | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers | Lung epithelial cells | miRNA | Cell culture media exosome purification and RNA isolation Kit | Exosomes | Small EVs |
150 | Vesiclepedia_2426 | 35939247 | Homo sapiens | Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
151 | Vesiclepedia_458 | 22740476 | Homo sapiens | Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4. | Colorectal cancer cells | Protein | - | Exosomes | EVs |
152 | Vesiclepedia_55 | 12147373 | Homo sapiens | Malignant effusions and immunogenic tumour-derived exosomes. | Malignant pleural effusions | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
153 | Vesiclepedia_493 | 23333927 | Homo sapiens | Characterization and proteomic analysis of ovarian cancer-derived exosomes. | Ovarian cancer cells | Protein | - | Exosomes | EVs |
154 | Vesiclepedia_2499 | 34329193 | Homo sapiens | CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis | Breast cancer cells | miRNA | Total Exosome Isolation Reagent | Exosomes | EVs |
155 | Vesiclepedia_2974 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Iodixanol density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
156 | Vesiclepedia_2247 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
157 | Vesiclepedia_717 | 26148937 | Homo sapiens | Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. | Cholangiocytes | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
158 | Vesiclepedia_2663 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
159 | Vesiclepedia_2233 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
160 | Vesiclepedia_771 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
161 | Vesiclepedia_948 | 28819550 | Mus musculus | Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses. | Bronchoalveolar lavage fluid | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
162 | Vesiclepedia_489 | 23260141 | Mus musculus | Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration. | Fibroblasts | Protein | - | Exosomes | EVs |
163 | Vesiclepedia_2743 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
164 | Vesiclepedia_2612 | 35443745 | Homo sapiens | Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts | Colorectal cancer cells |
Protein miRNA |
Ultracentrifugation ExoQuick Kit |
Exosomes | Small EVs |
165 | Vesiclepedia_3379 | 31848325 | Rattus norvegicus | Insulin-like growth factor-1 enchances neuroprotective effects of neural stem cell exosomes after spinal cord injury via an miR-219a-2-3p/YY1 mechanism | Neural stem cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
166 | Vesiclepedia_2911 | 26061593 | Homo sapiens | Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
167 | Vesiclepedia_1079 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
168 | Vesiclepedia_1832 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
169 | Vesiclepedia_877 | 29955024 | Homo sapiens | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
170 | Vesiclepedia_992 | 24434149 | Homo sapiens | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. | Ovarian cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
171 | Vesiclepedia_949 | 28819550 | Mus musculus | Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses. | Bronchoalveolar lavage fluid | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
172 | Vesiclepedia_898 | 26100252 | Homo sapiens | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts | Chronic lymphocytic leukemia cells | miRNA | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
173 | Vesiclepedia_325 | 19289371 | Homo sapiens | Exosomal microRNA: a diagnostic marker for lung cancer | Plasma | miRNA | Size exclusion chromatography Immunobeads (EpCAM) |
Exosomes | EVs |
174 | Vesiclepedia_1284 | 22345510 | Rattus norvegicus | Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. | Insulinoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
175 | Vesiclepedia_1270 | 24218614 | Homo sapiens | Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
176 | Vesiclepedia_102 | 21082674 | Homo sapiens | Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS. | Urine | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
177 | Vesiclepedia_3125 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Kidney cells | Protein | Differential centrifugation Filtration Sucrose density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
178 | Vesiclepedia_142 | 22723089 | Homo sapiens | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. | Prostate cancer cells | Protein | Sucrose density gradient | Exosomes | EVs |
179 | Vesiclepedia_524 | 23658846 | Mus musculus | Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. | Macrophage | Protein | - | Exosomes | EVs |
180 | Vesiclepedia_425 | 21179422 | Mus musculus | Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. | Mast cells | mRNA | - | Exosomes/Nanovesicles | EVs |
181 | Vesiclepedia_2987 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
182 | Vesiclepedia_2497 | 34329193 | Homo sapiens | CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis | Breast cancer cells |
Protein miRNA circRNA |
Total Exosome Isolation Reagent | Exosomes | EVs |
183 | Vesiclepedia_13 | 15326289 | Homo sapiens | Identification and proteomic profiling of exosomes in human urine. | Urine | Protein | Ultracentrifugation | Exosomes | EVs |
184 | Vesiclepedia_334 | 20976003 | Homo sapiens | Selective release of microRNA species from normal and malignant mammary epithelial cells | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration |
Exosomes | EVs |
185 | Vesiclepedia_108 | 21601258 | Homo sapiens | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. | Ascites |
Protein miRNA |
Differential centrifugation Sucrose density gradient Immunobeads (EpCAM, CD24) |
Exosomes | EVs |
186 | Vesiclepedia_967 | 25844599 | Homo sapiens | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. | Serum | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
187 | Vesiclepedia_344 | 22965126 | Mus musculus | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. | Neuronal cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
188 | Vesiclepedia_512 | 23533145 | Homo sapiens | In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. | Urine | Protein | - | Exosomes/Microvesicles | EVs |
189 | Vesiclepedia_2437 | 29335551 | Homo sapiens | Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer | Liver cancer cells |
Protein miRNA |
Filtration Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
190 | Vesiclepedia_1258 | 24400796 | Homo sapiens | Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. | Aqueous humor | Protein | ExoQuick | Exosomes | EVs |
191 | Vesiclepedia_2351 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
192 | Vesiclepedia_2746 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
193 | Vesiclepedia_2648 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
194 | Vesiclepedia_876 | 29955024 | Homo sapiens | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
195 | Vesiclepedia_2753 | 35173168 | Homo sapiens | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
196 | Vesiclepedia_3076 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
197 | Vesiclepedia_993 | 24434149 | Homo sapiens | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. | Ovarian cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
198 | Vesiclepedia_790 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
199 | Vesiclepedia_2429 | 35939247 | Homo sapiens | Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
200 | Vesiclepedia_816 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
201 | Vesiclepedia_3014 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
202 | Vesiclepedia_14 | 16081791 | Mus musculus | Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism. | Microglia | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
203 | Vesiclepedia_2248 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
204 | Vesiclepedia_1076 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
205 | Vesiclepedia_2990 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
206 | Vesiclepedia_3064 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Serum | Protein | Total Exosome isolation Kit | Exosomes | EVs |
207 | Vesiclepedia_3123 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Brain | Protein | Differential centrifugation Filtration Sucrose density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
208 | Vesiclepedia_2644 | 35649370 | Homo sapiens | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Mammary epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
209 | Vesiclepedia_2342 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
210 | Vesiclepedia_2468 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
211 | Vesiclepedia_994 | 24434149 | Homo sapiens | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. | Ovarian cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
212 | Vesiclepedia_1365 | 32132711 | Homo sapiens | Decoy exosomes provide protection against bacterial toxins | Lung cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
213 | Vesiclepedia_3276 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
214 | Vesiclepedia_3151 | 34887361 | Mus musculus | Endothelial cell-derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway | Endothelial cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
215 | Vesiclepedia_656 | 28753793 | Homo sapiens | MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma. | Serum | miRNA | Total Exosome Isolation Kit Differential centrifugation Ultracentrifugation Immunobeads (EpCAM) |
Exosomes | EVs |
216 | Vesiclepedia_1204 | 27780738 | Homo sapiens | Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. | Serum | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
217 | Vesiclepedia_990 | 25261472 | Homo sapiens | Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes/Microvesicles | EVs |
218 | Vesiclepedia_1363 | 32132711 | Homo sapiens | Decoy exosomes provide protection against bacterial toxins | Lung cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
219 | Vesiclepedia_24 | 11231627 | Homo sapiens | Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. | Melanoma cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
220 | Vesiclepedia_1455 | 31949130 | Homo sapiens | circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma | Lung cancer cells | circRNA | Total Exosome Isolation Reagent | Exosomes | Small EVs |
221 | Vesiclepedia_3071 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
222 | Vesiclepedia_1 | 6307529 | Ovis aries | Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. | Reticulocytes | Protein | - | Exosomes | EVs |
223 | Vesiclepedia_1698 | 34108659 | Mus musculus | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Serum | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
224 | Vesiclepedia_3147 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
225 | Vesiclepedia_1667 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Pancreatic cancer cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
226 | Vesiclepedia_796 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
227 | Vesiclepedia_2602 | 35351860 | Homo sapiens | Bone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5 | Bone marrow mesenchymal stem cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
228 | Vesiclepedia_470 | 23029346 | Fasciola hepatica | Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. | Fasciola hepatica | Protein | - | Exosomes/Extracellular vesicles/Microvesicles | EVs |
229 | Vesiclepedia_481 | 23161513 | Homo sapiens | Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. | Colorectal cancer cells | Protein | - | Exosomes | EVs |
230 | Vesiclepedia_742 | 28524762 | Rattus norvegicus | Exosomes promote restoration after an experimental animal model of intracerebral hemorrhage | Mesenchymal stem cells | Protein | miRCURY Exosome Isolation Kit | Exosomes | EVs |
231 | Vesiclepedia_3411 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
232 | Vesiclepedia_329 | 20304794 | Homo sapiens | Functional delivery of viral miRNAs via exosomes | B cells | miRNA | Differential centrifugation | Exosomes | EVs |
233 | Vesiclepedia_3158 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
234 | Vesiclepedia_217 | 21293856 | Homo sapiens | Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC | Serum | Protein | Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
235 | Vesiclepedia_2446 | 34489604 | Mus musculus | Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 | Hepatocytes |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
236 | Vesiclepedia_3013 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
237 | Vesiclepedia_214 | 21364924 | Homo sapiens | Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells | T cells | Protein | Differential centrifugation Ultracentrifugation Filtration Sucrose density gradient FACS |
Exosomes | EVs |
238 | Vesiclepedia_3156 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
239 | Vesiclepedia_2255 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
240 | Vesiclepedia_3077 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
241 | Vesiclepedia_1355 | 32438511 | Homo sapiens | Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion | Colorectal cancer cells | Protein | Differential centrifugation Filtration OptiPrep density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
242 | Vesiclepedia_9 | 12626558 | Mus musculus | Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. | Macrophage | Protein | Differential centrifugation | Exosomes | EVs |
243 | Vesiclepedia_61 | 17133577 | Mus musculus | Association of citrullinated proteins with synovial exosomes. | Synovial fluid | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
244 | Vesiclepedia_725 | 25471207 | Homo sapiens | Intraluminal proteome and peptidome of human urinary extracellular vesicles. | Urine | Protein | Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration |
Exosomes | EVs |
245 | Vesiclepedia_1683 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
246 | Vesiclepedia_2755 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
247 | Vesiclepedia_2350 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Stromal vascular fraction | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
248 | Vesiclepedia_3150 | 29438363 | Homo sapiens | CD9-positive exosomes from cancer-associated fibroblasts stimulate the migration ability of scirrhous-type gastric cancer cells | Fibroblasts | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
249 | Vesiclepedia_3122 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Brain | Protein | Differential centrifugation Filtration Sucrose density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
250 | Vesiclepedia_1818 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
251 | Vesiclepedia_3412 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
252 | Vesiclepedia_2459 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
253 | Vesiclepedia_792 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
254 | Vesiclepedia_864 | 22046311 | Mus musculus | Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections | Plasma | Protein | Differential centrifugation Filtration Sucrose density gradient Ultracentrifugation |
Exosomes | EVs |
255 | Vesiclepedia_2641 | 35649370 | Homo sapiens | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Cervical cancer cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
256 | Vesiclepedia_1827 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells |
Protein miRNA |
Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
257 | Vesiclepedia_1289 | 19912576 | Homo sapiens | HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. | Cervical cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
258 | Vesiclepedia_809 | 29932869 | Mus musculus | Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy | Schwann cells | protein | Filtration Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
259 | Vesiclepedia_2668 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
260 | Vesiclepedia_772 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
261 | Vesiclepedia_3130 | 34500436 | Homo sapiens | MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
262 | Vesiclepedia_2695 | 35210436 | Homo sapiens | M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway | Macrophage | mRNA | Total Exosome Isolation Reagent | Exosomes | Small EVs |
263 | Vesiclepedia_2766 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
264 | Vesiclepedia_2029 | 35986010 | Homo sapiens | Exosomal miR-155-5p derived from glioma stem-like cells promotes mesenchymal transition via targeting ACOT12 | Glioblastoma cells |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
265 | Vesiclepedia_3011 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
266 | Vesiclepedia_522 | 23645497 | Canis lupus familiaris | Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. | Kidney cells | Protein | - | Exosomes/Extracellular vesicles | EVs |
267 | Vesiclepedia_1842 | 36408942 | Homo sapiens | Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells | Mesenchymal stem cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
268 | Vesiclepedia_3002 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
269 | Vesiclepedia_2324 | 31807237 | Homo sapiens | Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
270 | Vesiclepedia_741 | 25157233 | Homo sapiens | Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. | Placenta | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
271 | Vesiclepedia_3028 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
272 | Vesiclepedia_716 | 26317203 | Homo sapiens | Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis. | Osteosarcoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
273 | Vesiclepedia_998 | 24355714 | Homo sapiens | Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium. | Leukemia cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
274 | Vesiclepedia_1218 | 27872147 | Homo sapiens | Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. | Islets | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
275 | Vesiclepedia_903 | 25053844 | Homo sapiens | Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons | Neuroblastoma cells | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
276 | Vesiclepedia_1326 | 33431899 | Homo sapiens | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Faeces |
Protein Lipid |
Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
277 | Vesiclepedia_764 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
278 | Vesiclepedia_3019 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
279 | Vesiclepedia_1933 | 36103526 | Homo sapiens | Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases | Hepatic stellate cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
280 | Vesiclepedia_101 | 21828046 | Rattus norvegicus | The proteo-lipidic composition of exosomes changes during reticulocyte maturation. | Reticulocytes |
Protein Lipids |
Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
281 | Vesiclepedia_831 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
282 | Vesiclepedia_803 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
283 | Vesiclepedia_1080 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
284 | Vesiclepedia_2662 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
285 | Vesiclepedia_58 | 17700640 | Homo sapiens | CD24 is a marker of exosomes secreted into urine and amniotic fluid. | Amniotic fluid | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
286 | Vesiclepedia_1462 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
287 | Vesiclepedia_20 | 17956143 | Homo sapiens | Proteomic analysis of microvesicles derived from human colorectal cancer cells. | Colorectal cancer cells | Protein | Differential centrifugation Sucrose density gradient Diafiltration |
Exosomes | EVs |
288 | Vesiclepedia_3286 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
289 | Vesiclepedia_3060 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic duct epithelial cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
290 | Vesiclepedia_2614 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
291 | Vesiclepedia_1278 | 22437826 | Drosophila melanogaster | Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. | Drosophila S2 cells | Protein | Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
292 | Vesiclepedia_1016 | 22711894 | Homo sapiens | Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. | Macrophage |
Protein Lipids |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
293 | Vesiclepedia_657 | 28753793 | Homo sapiens | MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma. | Serum | miRNA | Total Exosome Isolation Kit Differential centrifugation Ultracentrifugation Immunobeads (EpCAM) |
Exosomes | EVs |
294 | Vesiclepedia_3049 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
295 | Vesiclepedia_3035 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
296 | Vesiclepedia_1335 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | Plasma |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
297 | Vesiclepedia_2474 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
298 | Vesiclepedia_821 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Filtration Ultracentrifugation Sucrose and deuterium oxide density cushion |
Exosomes | EVs |
299 | Vesiclepedia_3135 | 34500436 | Homo sapiens | MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
300 | Vesiclepedia_3281 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
301 | Vesiclepedia_3034 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
302 | Vesiclepedia_3106 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Hippocampal neuronal cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
303 | Vesiclepedia_480 | 23161513 | Homo sapiens | Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. | Colorectal cancer cells | Protein | - | Exosomes | EVs |
304 | Vesiclepedia_2460 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
305 | Vesiclepedia_3560 | 28409562 | Homo sapiens | Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation | Colon cancer cells | dsDNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
306 | Vesiclepedia_659 | 29982104 | Mus musculus | NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo. | Macrophage | Protein | Differential centrifugation Ultracentrifugation Ultrafiltration |
Exosomes | EVs |
307 | Vesiclepedia_887 | 25102470 | Homo sapiens | Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
308 | Vesiclepedia_3533 | - | Homo sapiens | Small RNA Sequencing of Circulating Small Extracellular Vesicle MicroRNAs in Patients with Amyotrophic Lateral Sclerosis | Serum | miRNA | ExoEasy | Exosomes | Small EVs |
309 | Vesiclepedia_1838 | 36408942 | Rattus norvegicus | Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells | Bone marrow mesenchymal stem cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
310 | Vesiclepedia_189 | 21741384 | Homo sapiens | A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma | Plasma | Protein | Differential centrifugation Filtration |
Exosomes | EVs |
311 | Vesiclepedia_1141 | 23454749 | Homo sapiens | BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. | Bone marrow mesenchymal stromal cells | Protein | Differential centrifugation Ultracentrifugation Filtration ExoQuick |
Exosomes | EVs |
312 | Vesiclepedia_1155 | 21212511 | Homo sapiens | Proteomic analysis of two types of exosomes in human whole saliva. | Saliva | Protein | Differential centrifugation Filtration Ultracentrifugation Gel filtration |
Exosomes | EVs |
313 | Vesiclepedia_2642 | 35649370 | Homo sapiens | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Mammary epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
314 | Vesiclepedia_882 | 29955024 | Homo sapiens | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells | Myeloid leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
315 | Vesiclepedia_3197 | 34690112 | Homo sapiens | Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling | Plasma |
Protein lncRNA |
ExoQuick Kit | Exosomes | EVs |
316 | Vesiclepedia_964 | 25844599 | Homo sapiens | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
317 | Vesiclepedia_1219 | 27872147 | Homo sapiens | Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. | Islets | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
318 | Vesiclepedia_2777 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
319 | Vesiclepedia_2490 | 34388111 | Homo sapiens | miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis | Monocytic leukemia cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
320 | Vesiclepedia_35 | 19367702 | Rattus norvegicus | Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. | Hepatocytes | Protein | Differential centrifugation Filtration Sucrose density gradient |
Exosomes | EVs |
321 | Vesiclepedia_538 | 23844026 | Homo sapiens | Characterization of human thymic exosomes. | Thymus | Protein | - | Exosomes | EVs |
322 | Vesiclepedia_2000 | 34112803 | Homo sapiens | Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution | Plasma | Protein | Size exclusion chromatography Centrifugal ultrafiltration |
Exosomes | Small EVs |
323 | Vesiclepedia_2634 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
324 | Vesiclepedia_1658 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Pancreatic cancer cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
325 | Vesiclepedia_822 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
326 | Vesiclepedia_2430 | 35939247 | Homo sapiens | Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
327 | Vesiclepedia_1339 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | Liver | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
328 | Vesiclepedia_444 | 22418980 | Homo sapiens | A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. | Urine | Protein | - | Exosomes | EVs |
329 | Vesiclepedia_33 | 21136642 | Mus musculus | Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? | Oligodendrocytes | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
330 | Vesiclepedia_862 | 25776846 | Homo sapiens | Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens | Epithelial cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
331 | Vesiclepedia_143 | 22723089 | Homo sapiens | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. | Prostate cancer cells | Protein | Sucrose density gradient | Exosomes | EVs |
332 | Vesiclepedia_2748 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
333 | Vesiclepedia_1449 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Plasma | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
334 | Vesiclepedia_3006 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
335 | Vesiclepedia_343 | 22965126 | Mus musculus | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. | Neuronal cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
336 | Vesiclepedia_2636 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
337 | Vesiclepedia_2319 | 31762962 | Homo sapiens | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers | Plasma |
Protein small RNA |
ExoQuick Kit | Extracellular vesicles/Exosomes | EVs |
338 | Vesiclepedia_2638 | 35649370 | Homo sapiens | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Cervical cancer cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
339 | Vesiclepedia_353 | 24115447 | Homo sapiens | Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma | Plasma | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
340 | Vesiclepedia_333 | 20976003 | Homo sapiens | Selective release of microRNA species from normal and malignant mammary epithelial cells | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration |
Exosomes | EVs |
341 | Vesiclepedia_336 | 20976003 | Homo sapiens | Selective release of microRNA species from normal and malignant mammary epithelial cells | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration |
Exosomes | EVs |
342 | Vesiclepedia_1000 | 24079734 | Mus musculus | Immunostimulatory activity of murine keratinocyte-derived exosomes. | Keratinocytes | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
343 | Vesiclepedia_808 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
344 | Vesiclepedia_3162 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
345 | Vesiclepedia_3146 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
346 | Vesiclepedia_2670 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
347 | Vesiclepedia_1251 | 24939845 | Homo sapiens | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. | Leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
348 | Vesiclepedia_835 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
349 | Vesiclepedia_926 | 25483805 | Homo sapiens | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties | Embryonic kidney cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
350 | Vesiclepedia_897 | 26100252 | Homo sapiens | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts | Chronic lymphocytic leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
351 | Vesiclepedia_738 | 25157233 | Homo sapiens | Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. | Placenta choriocarcinoma cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
352 | Vesiclepedia_2992 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
353 | Vesiclepedia_44 | 19028452 | Homo sapiens | Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein. | Plasma | Protein | Filtration Size exclusion chromatography Sucrose density gradient |
Exosomes | EVs |
354 | Vesiclepedia_1820 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
355 | Vesiclepedia_3022 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
356 | Vesiclepedia_2666 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
357 | Vesiclepedia_1535 | 33589572 | Homo sapiens | Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis | Lung cancer cells | Protein | Centrifugation ExoQuick Kit |
Exosomes | Small EVs |
358 | Vesiclepedia_553 | 24009898 | Mus musculus | Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. | Cardiomyocytes | mRNA | - | Exosomes/Extracellular vesicles | EVs |
359 | Vesiclepedia_238 | 21293856 | Homo sapiens | Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC | Ascites | Protein | Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
360 | Vesiclepedia_3058 | 33827783 | Mus musculus | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
361 | Vesiclepedia_2997 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
362 | Vesiclepedia_3406 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph |
Protein miRNA |
Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
363 | Vesiclepedia_18 | 11907077 | Homo sapiens | TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. | T cells | Protein | Filtration Ultracentrifugation |
Exosomes | EVs |
364 | Vesiclepedia_2 | 3597417 | Ovis aries | Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). | Reticulocytes |
Protein Lipids |
Differential centrifugation | Exosomes | EVs |
365 | Vesiclepedia_3409 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
366 | Vesiclepedia_1360 | 32132711 | Homo sapiens | Decoy exosomes provide protection against bacterial toxins | Lung cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
367 | Vesiclepedia_126 | - | Homo sapiens | Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? | Mesenchymal stem cells | Protein | HPLC | Exosomes | EVs |
368 | Vesiclepedia_1116 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
369 | Vesiclepedia_3584 | 24398677 | Homo sapiens | Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer | Serum | dsDNA-mutated | Filtration Ultracentrifugation |
Exosomes | Small EVs |
370 | Vesiclepedia_72 | 19801663 | Homo sapiens | Microenvironmental pH is a key factor for exosome traffic in tumor cells. | Melanoma cells |
Protein Lipids |
Differential centrifugation | Exosomes | EVs |
371 | Vesiclepedia_215 | 21364924 | Homo sapiens | Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells | B cells | Protein | Differential centrifugation Ultracentrifugation Filtration Sucrose density gradient FACS |
Exosomes | EVs |
372 | Vesiclepedia_452 | 22506041 | Mus musculus | Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells. | Cardiomyocytes | mRNA | - | Exosomes/Membrane vesicles/Microvesicles/Prostasomes | EVs |
373 | Vesiclepedia_915 | 28687758 | Sus scrofa | Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers | Polarised retinal pigmented epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
374 | Vesiclepedia_2280 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
375 | Vesiclepedia_1435 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
376 | Vesiclepedia_1236 | 25421927 | Heligmosomoides polygyrus | Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. | Heligmosomoides polygyrus |
miRNA Protein |
Filtration Ultracentrifugation |
Exosomes | EVs |
377 | Vesiclepedia_435 | 22031862 | Mus musculus | Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. | Dendritic cells | miRNA | - | Exosomes/Nanovesicles | EVs |
378 | Vesiclepedia_2439 | 29335551 | Homo sapiens | Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer | Liver cancer cells |
Protein miRNA |
Filtration Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
379 | Vesiclepedia_140 | 22723089 | Homo sapiens | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. | Prostate cancer cells | Protein | Sucrose density gradient | Exosomes | EVs |
380 | Vesiclepedia_3283 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
381 | Vesiclepedia_910 | 28687758 | Sus scrofa | Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers | Polarised retinal pigmented epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
382 | Vesiclepedia_1133 | 23861904 | Homo sapiens | Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. | Placental mesenchymal stem cells | Protein | Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation |
Exosomes | EVs |
383 | Vesiclepedia_121 | 21276792 | Homo sapiens | Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells. | Trophoblast cells | Protein | Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
384 | Vesiclepedia_2353 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
385 | Vesiclepedia_1134 | 23861904 | Homo sapiens | Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. | Placental mesenchymal stem cells | Protein | Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation |
Exosomes | EVs |
386 | Vesiclepedia_966 | 25844599 | Homo sapiens | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. | Serum | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
387 | Vesiclepedia_2629 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
388 | Vesiclepedia_1912 | 36270983 | Mus musculus | NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancer | Lung cancer cells | Protein | Centrifugation Exosome Isolation Reagent |
Exosomes | Small EVs |
389 | Vesiclepedia_419 | 21136642 | Mus musculus | Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? | Oligodendrocytes | Protein | - | Exosomes | EVs |
390 | Vesiclepedia_1004 | 23463506 | Homo sapiens | The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. | T cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
391 | Vesiclepedia_3540 | 35742955 | Homo sapiens | Genomic Analysis Made It Possible to Identify Gene-Driver Alterations Covering the Time Window between Diagnosis of Neuroblastoma 4S and the Progression to Stage 4 | Plasma | dsDNA | Exo-RNeasy Kit | Exosomes | Small EVs |
392 | Vesiclepedia_2627 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
393 | Vesiclepedia_1659 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Embryonic kidney cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
394 | Vesiclepedia_53 | 14975938 | Homo sapiens | Proteomic analysis of exosomes isolated from human malignant pleural effusions. | Malignant pleural effusions | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
395 | Vesiclepedia_2428 | 35939247 | Homo sapiens | Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
396 | Vesiclepedia_989 | 25261472 | Homo sapiens | Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes/Microvesicles | EVs |
397 | Vesiclepedia_885 | 29955024 | Homo sapiens | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells | Myeloid leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
398 | Vesiclepedia_10 | 11390481 | Mus musculus | Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. | Dendritic cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
399 | Vesiclepedia_1096 | 24976626 | Homo sapiens | Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells. | Renal proximal tubule cells | Protein | Differential centrifugation Ultracentrifugation Immunoaffinity |
Exosomes | EVs |
400 | Vesiclepedia_323 | 20304794 | Homo sapiens | Functional delivery of viral miRNAs via exosomes | B cells | Protein | Differential centrifugation | Exosomes | EVs |
401 | Vesiclepedia_988 | 25261472 | Homo sapiens | Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes/Microvesicles | EVs |
402 | Vesiclepedia_2989 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
403 | Vesiclepedia_1220 | 27872147 | Rattus norvegicus | Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. | Insulinoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
404 | Vesiclepedia_64 | 18520029 | Homo sapiens | Exosome-like vesicles with dipeptidyl peptidase IV in human saliva. | Saliva | Protein | Filtration Diafiltration Gel filtration |
Exosomes | EVs |
405 | Vesiclepedia_86 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
406 | Vesiclepedia_878 | 29955024 | Homo sapiens | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
407 | Vesiclepedia_2756 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
408 | Vesiclepedia_551 | 24009886 | Homo sapiens | Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. | Endothelial cells | Protein | - | Exosomes/Extracellular vesicles | EVs |
409 | Vesiclepedia_1821 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
410 | Vesiclepedia_2246 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
411 | Vesiclepedia_2232 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
412 | Vesiclepedia_661 | 29956871 | Homo sapiens | Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis | Bronchoalveolar lavage fluid | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
413 | Vesiclepedia_2279 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
414 | Vesiclepedia_1545 | 33767144 | Homo sapiens | Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells | Cervical cancer cells | Protein | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
415 | Vesiclepedia_1013 | 22711894 | Homo sapiens | Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. | Macrophage |
Protein Lipids |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
416 | Vesiclepedia_134 | 15304316 | Rattus norvegicus | PLD2 is enriched on exosomes and its activity is correlated to the release of exosomes | Basophilic leukemia cells |
Protein Lipids |
Differential centrifugation | Exosomes | EVs |
417 | Vesiclepedia_654 | 28290293 | Bos taurus | Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. | Bovine milk | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
418 | Vesiclepedia_1571 | 33738083 | Homo sapiens | Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases | Colorectal cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
419 | Vesiclepedia_75 | 19381331 | Homo sapiens | High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. | Plasma | Protein | Differential centrifugation | Exosomes | EVs |
420 | Vesiclepedia_549 | 24009881 | Homo sapiens | Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. | Colorectal cancer cells | Protein | - | Exosomes/Extracellular vesicles/Microvesicles/Ectosomes | EVs |
421 | Vesiclepedia_107 | 21763319 | Homo sapiens | Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. | Pancreatic cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration Ultracentrifugation |
Exosomes | EVs |
422 | Vesiclepedia_1262 | 24371517 | Homo sapiens | Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. | Urine | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
423 | Vesiclepedia_517 | 23585443 | Homo sapiens | Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. | Colorectal cancer cells | Protein | - | Exosomes/Membrane vesicles | EVs |
424 | Vesiclepedia_1092 | 25065644 | Homo sapiens | Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. | Duodenal cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration |
Exosomes | EVs |
425 | Vesiclepedia_2343 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
426 | Vesiclepedia_2770 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Size exclusion chromatography |
Exosomes | Small EVs |
427 | Vesiclepedia_45 | 18589210 | Homo sapiens | MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. | Serum |
Protein miRNA |
Ultracentrifugation Immunobeads (EpCAM) |
Exosomes | EVs |
428 | Vesiclepedia_1008 | 23463506 | Homo sapiens | The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. | T cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
429 | Vesiclepedia_51 | 14975938 | Homo sapiens | Proteomic analysis of exosomes isolated from human malignant pleural effusions. | Malignant pleural effusions | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
430 | Vesiclepedia_1247 | 25167841 | Homo sapiens | Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. | Serum | Protein | CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips | Exosomes | EVs |
431 | Vesiclepedia_2317 | 31762962 | Homo sapiens | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers | Plasma |
Protein small RNA |
ExoQuick Kit | Extracellular vesicles/Exosomes | EVs |
432 | Vesiclepedia_2249 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
433 | Vesiclepedia_281 | 15499615 | Homo sapiens | Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer | Lung cancer cells | mRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
434 | Vesiclepedia_1358 | 32438511 | Homo sapiens | Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion | Colorectal cancer cells | Protein | Differential centrifugation Filtration OptiPrep density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
435 | Vesiclepedia_1261 | 24371517 | Homo sapiens | Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
436 | Vesiclepedia_1015 | 22711894 | Homo sapiens | Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. | Macrophage |
Protein Lipids |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
437 | Vesiclepedia_42 | 15908444 | Homo sapiens | Exosomal-like vesicles are present in human blood plasma. | Bone marrow cells | Protein | Differential centrifugation Filtration Sucrose density gradient |
Exosomes | EVs |
438 | Vesiclepedia_1452 | 31949130 | Homo sapiens | circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma | Lung epithelial cells | circRNA | Total Exosome Isolation Reagent | Exosomes | Small EVs |
439 | Vesiclepedia_986 | 25261472 | Homo sapiens | Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes/Microvesicles | EVs |
440 | Vesiclepedia_424 | 21179422 | Mus musculus | Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. | Mast cells | mRNA | - | Exosomes/Nanovesicles | EVs |
441 | Vesiclepedia_36 | 19367702 | Mus musculus | Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. | Hepatocytes | Protein | Differential centrifugation Filtration |
Exosomes | EVs |
442 | Vesiclepedia_692 | 28170197 | Homo sapiens | Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 | Adipose-derived mesenchymal stem cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
443 | Vesiclepedia_1523 | 33911067 | Homo sapiens | Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis | Breast cancer cells | circRNAs | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
444 | Vesiclepedia_879 | 29955024 | Homo sapiens | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells | Myeloid leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
445 | Vesiclepedia_1233 | 25469510 | Homo sapiens | GAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathways. | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
446 | Vesiclepedia_3131 | 34500436 | Homo sapiens | MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
447 | Vesiclepedia_1321 | 33431899 | Mus musculus | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Faeces | Lipid | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
448 | Vesiclepedia_1052 | 29115712 | Mus musculus | Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
449 | Vesiclepedia_132 | 19188015 | Homo sapiens | Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes | Ovarian cancer cells |
Protein Lipids |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
450 | Vesiclepedia_1962 | 36417505 | Homo sapiens | A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER) | Plasma | Protein | Acoustic nanoscale separation via wave-pillar excitation resonance (ANSWER) | Exosomes | Small EVs |
451 | Vesiclepedia_2296 | 29339034 | Homo sapiens | Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer | Pancreatic duct fluid | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
452 | Vesiclepedia_2767 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Ultracentrifugation |
Exosomes | Small EVs |
453 | Vesiclepedia_77 | 20224111 | Homo sapiens | Proteomics analysis of bladder cancer exosomes. | Urine | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
454 | Vesiclepedia_904 | 25053844 | Homo sapiens | Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons | Neuroblastoma cells | miRNA | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
455 | Vesiclepedia_3137 | 34500436 | Homo sapiens | MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
456 | Vesiclepedia_117 | 21505438 | Homo sapiens | Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. | Dendritic cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
457 | Vesiclepedia_2253 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
458 | Vesiclepedia_2322 | 31762962 | Homo sapiens | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers | Monocytes | miRNA | Cell culture media exosome purification and RNA isolation Kit | Exosomes | Small EVs |
459 | Vesiclepedia_1676 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
460 | Vesiclepedia_1090 | 25065644 | Homo sapiens | Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. | Duodenal cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration |
Exosomes | EVs |
461 | Vesiclepedia_1083 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
462 | Vesiclepedia_2352 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Stromal vascular fraction | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
463 | Vesiclepedia_17 | 11907077 | Homo sapiens | TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. | T cells | Protein | Filtration Ultracentrifugation |
Exosomes | EVs |
464 | Vesiclepedia_2005 | 34112803 | Mus musculus | Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Centrifugal ultrafiltration |
Exosomes | Small EVs |
465 | Vesiclepedia_2773 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Saliva | Protein | Filtration Ultracentrifugation |
Exosomes | Small EVs |
466 | Vesiclepedia_2623 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
467 | Vesiclepedia_818 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
468 | Vesiclepedia_63 | 19056867 | Homo sapiens | Large-scale proteomics and phosphoproteomics of urinary exosomes. | Urine | Protein | Differential centrifugation | Exosomes | EVs |
469 | Vesiclepedia_2637 | 35649370 | Homo sapiens | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
470 | Vesiclepedia_2764 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
471 | Vesiclepedia_2320 | 31762962 | Homo sapiens | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers | Lung epithelial cells | miRNA | Cell culture media exosome purification and RNA isolation Kit | Exosomes | Small EVs |
472 | Vesiclepedia_1830 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
473 | Vesiclepedia_487 | 23230278 | Homo sapiens | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. | Colorectal cancer cells | Protein | - | Exosomes/Extracellular vesicles/Microvesicles | EVs |
474 | Vesiclepedia_1332 | 33431899 | Mus musculus | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Colorectal cancer cells | Protein | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
475 | Vesiclepedia_1522 | 33911067 | Homo sapiens | Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis | Breast cancer cells | circRNAs | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
476 | Vesiclepedia_135 | 2777884 | Cavia porcellus | Asymmetric Distribution of Phospholipids in the Membrane of Vesicles Released During In Vitro Maturation of Guinea Pig Reticulocytes: Evidence Precluding a Role for Aminophospholipid Translocase | Reticulocytes |
Proteins Lipids |
Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
477 | Vesiclepedia_1114 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
478 | Vesiclepedia_2620 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
479 | Vesiclepedia_710 | 28811610 | Homo sapiens | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
480 | Vesiclepedia_1275 | 23489476 | Sus scrofa | Boar seminal plasma exosomes: effect on sperm function and protein identification by sequencing. | Seminal plasma | Protein | Differential centrifugation Gel filtration Ultracentrifugation |
Exosomes | EVs |
481 | Vesiclepedia_1841 | 36408942 | Rattus norvegicus | Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells | Bone marrow mesenchymal stem cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
482 | Vesiclepedia_2665 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
483 | Vesiclepedia_66 | 19199708 | Homo sapiens | Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). | Saliva | Protein | Differential centrifugation | Exosomes | EVs |
484 | Vesiclepedia_3148 | 29438363 | Homo sapiens | CD9-positive exosomes from cancer-associated fibroblasts stimulate the migration ability of scirrhous-type gastric cancer cells | Fibroblasts | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
485 | Vesiclepedia_787 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
486 | Vesiclepedia_999 | 24355714 | Homo sapiens | Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium. | Leukemia cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
487 | Vesiclepedia_519 | 23585444 | Homo sapiens | Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. | Malignant pleural effusions | Protein | - | Exosomes/Microvesicles/Ectosomes/Microparticles | EVs |
488 | Vesiclepedia_1671 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography |
Exosomes | Small EVs |
489 | Vesiclepedia_653 | 28290293 | Homo sapiens | Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. | Breast milk | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
490 | Vesiclepedia_3054 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Plasma | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
491 | Vesiclepedia_98 | 21828046 | Rattus norvegicus | The proteo-lipidic composition of exosomes changes during reticulocyte maturation. | Reticulocytes |
Protein Lipids |
Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
492 | Vesiclepedia_1834 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
493 | Vesiclepedia_1264 | 24371517 | Homo sapiens | Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. | Urine | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
494 | Vesiclepedia_861 | 25776846 | Homo sapiens | Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens | Epithelial cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
495 | Vesiclepedia_1840 | 36408942 | Rattus norvegicus | Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells | Bone marrow mesenchymal stem cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
496 | Vesiclepedia_1160 | 22641613 | Homo sapiens | Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. | Urine | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
497 | Vesiclepedia_2421 | 35939247 | Homo sapiens | Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
498 | Vesiclepedia_2006 | 34112803 | Mus musculus | Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Centrifugal ultrafiltration |
Exosomes | Small EVs |
499 | Vesiclepedia_978 | 22808001 | Homo sapiens | Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. | Serum | Protein | Filtration ExoQuick |
Exosomes | EVs |
500 | Vesiclepedia_1110 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
501 | Vesiclepedia_1824 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Serum | miRNA | Total Exosome Isolation Kit | Exosomes | Small EVs |
502 | Vesiclepedia_1539 | 33658392 | Homo sapiens | Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma | Lung epithelial cells | miRNA | Minute High-Efficiency Exosome Precipitation Reagent Filtration |
Exosomes | Small EVs |
503 | Vesiclepedia_556 | 24069378 | Homo sapiens | Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression. | Neuroblastoma cells | Protein | - | Exosomes/Membrane vesicles | EVs |
504 | Vesiclepedia_3575 | 31608233 | Homo sapiens | Double-Stranded DNA in Exosomes of Malignant Pleural Effusions as a Novel DNA Source for EGFR Mutation Detection in Lung Adenocarcinoma | Pleural effusion | dsDNA-mutated | ExoQuick Kit | Exosomes | Small EVs |
505 | Vesiclepedia_2967 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
506 | Vesiclepedia_3115 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Podocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
507 | Vesiclepedia_441 | 22251860 | Homo sapiens | RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls. | Serum | mRNA | - | Exosomes/Microvesicles | EVs |
508 | Vesiclepedia_927 | 25483805 | Homo sapiens | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties | Embryonic kidney cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
509 | Vesiclepedia_1120 | 24347249 | Homo sapiens | Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation ExoQuick |
Exosomes | EVs |
510 | Vesiclepedia_48 | 17641064 | Homo sapiens | Exosomes with immune modulatory features are present in human breast milk. | Breast milk | Protein | Differential centrifugation Filtration Sucrose density gradient |
Exosomes | EVs |
511 | Vesiclepedia_1808 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | ExoQuick Kit | Exosomes | Small EVs |
512 | Vesiclepedia_2235 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
513 | Vesiclepedia_788 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
514 | Vesiclepedia_1112 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
515 | Vesiclepedia_521 | 23645497 | Canis lupus familiaris | Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. | Kidney cells | Protein | - | Exosomes/Extracellular vesicles | EVs |
516 | Vesiclepedia_1253 | 24939845 | Homo sapiens | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
517 | Vesiclepedia_1548 | 33638284 | Canis lupus familiaris | Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition | Kidney cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
518 | Vesiclepedia_819 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
519 | Vesiclepedia_1836 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
520 | Vesiclepedia_1290 | 19912576 | Homo sapiens | HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. | Lymphoblasts | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
521 | Vesiclepedia_3368 | 34887515 | Homo sapiens | Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets | Colon cancer cells | Protein | Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation |
Exosomes | Small EVs |
522 | Vesiclepedia_2240 | 36648227 | Mus musculus | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Macrophage | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
523 | Vesiclepedia_1150 | 22807456 | Homo sapiens | Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells. | Lymphocytes | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
524 | Vesiclepedia_23 | 11231627 | Mus musculus | Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. | Breast cancer cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
525 | Vesiclepedia_3577 | 35742955 | Homo sapiens | Genomic Analysis Made It Possible to Identify Gene-Driver Alterations Covering the Time Window between Diagnosis of Neuroblastoma 4S and the Progression to Stage 4 | Plasma | dsDNA-mutated | Exo-RNeasy Kit | Exosomes | Small EVs |
526 | Vesiclepedia_349 | 22285593 | Homo sapiens | Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. | Colorectal cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
527 | Vesiclepedia_2283 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
528 | Vesiclepedia_832 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
529 | Vesiclepedia_79 | 20458337 | Homo sapiens | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 | B cells | Protein | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Exosomes | EVs |
530 | Vesiclepedia_1999 | 34112803 | Homo sapiens | Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Centrifugal ultrafiltration |
Exosomes | Small EVs |
531 | Vesiclepedia_1094 | 25065644 | Homo sapiens | Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. | Duodenal cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration |
Exosomes | EVs |
532 | Vesiclepedia_1527 | 33752173 | Homo sapiens | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
533 | Vesiclepedia_2619 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
534 | Vesiclepedia_3414 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
535 | Vesiclepedia_1825 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Serum | miRNA | Total Exosome Isolation Kit | Exosomes | Small EVs |
536 | Vesiclepedia_3119 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Kidney cells | Protein | Differential centrifugation Filtration Sucrose density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
537 | Vesiclepedia_972 | 22808001 | Homo sapiens | Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. | Serum | Protein | Filtration ExoQuick |
Exosomes | EVs |
538 | Vesiclepedia_2742 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
539 | Vesiclepedia_1325 | 33431899 | Homo sapiens | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Faeces |
Protein Lipid |
Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
540 | Vesiclepedia_1109 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
541 | Vesiclepedia_1536 | 33589572 | Homo sapiens | Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis | Lung cancer cells | Protein | Centrifugation ExoQuick Kit |
Exosomes | Small EVs |
542 | Vesiclepedia_1198 | 27883272 | Homo sapiens | Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. | Serum |
miRNA Metabolites |
ExoQuick | Exosomes | EVs |
543 | Vesiclepedia_547 | 24009880 | Homo sapiens | Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. | Mast cells | miRNA | - | Exosomes/Extracellular vesicles | EVs |
544 | Vesiclepedia_2470 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
545 | Vesiclepedia_1246 | 25167841 | Homo sapiens | Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. | Serum | Protein | CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips | Exosomes | EVs |
546 | Vesiclepedia_1812 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum | miRNA | ExoQuick Kit | Exosomes | Small EVs |
547 | Vesiclepedia_689 | 28170197 | Homo sapiens | Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 | Adipose-derived mesenchymal stem cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
548 | Vesiclepedia_70 | 19812188 | Rattus norvegicus | Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII. | Dendritic cells | Protein | Differential centrifugation | Exosomes | EVs |
549 | Vesiclepedia_1697 | 34108659 | Mus musculus | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Monocyte/macrophage-like cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
550 | Vesiclepedia_1146 | 23173708 | Rattus norvegicus | Wnt3a induces exosome secretion from primary cultured rat microglia. | Primary microglial cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
551 | Vesiclepedia_919 | 28687758 | Sus scrofa | Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers | Polarised retinal pigmented epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
552 | Vesiclepedia_1205 | 27780738 | Homo sapiens | Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. | Serum | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
553 | Vesiclepedia_2425 | 35939247 | Homo sapiens | Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
554 | Vesiclepedia_1434 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
555 | Vesiclepedia_1276 | 23344851 | Rattus norvegicus | Urinary exosomes and diabetic nephropathy: a proteomic approach. | Urine | Protein | Ultracentrifugation | Exosomes | EVs |
556 | Vesiclepedia_341 | 20615901 | Homo sapiens | Export of microRNAs and microRNA-protective protein by mammalian cells | Epithelial cells | miRNA | Differential centrifugation | Exosomes | EVs |
557 | Vesiclepedia_1249 | 24939845 | Homo sapiens | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. | Leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
558 | Vesiclepedia_2660 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
559 | Vesiclepedia_1702 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Urine | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
560 | Vesiclepedia_2030 | 35986010 | Homo sapiens | Exosomal miR-155-5p derived from glioma stem-like cells promotes mesenchymal transition via targeting ACOT12 | Glial cells |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
561 | Vesiclepedia_1140 | 23454749 | Homo sapiens | BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. | Bone marrow mesenchymal stromal cells | Protein | Differential centrifugation Ultracentrifugation Filtration ExoQuick |
Exosomes | EVs |
562 | Vesiclepedia_1108 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
563 | Vesiclepedia_331 | 19627513 | Homo sapiens | Exosomes from human saliva as a source of microRNA biomarkers | Saliva |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
564 | Vesiclepedia_80 | 20458337 | Homo sapiens | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 | B cells | Protein | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Exosomes | EVs |
565 | Vesiclepedia_1806 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
566 | Vesiclepedia_691 | 28170197 | Homo sapiens | Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 | Endometrium-derived mesenchymal stem cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
567 | Vesiclepedia_900 | 26100252 | Homo sapiens | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts | Chronic lymphocytic leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
568 | Vesiclepedia_2635 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
569 | Vesiclepedia_1244 | 25167841 | Homo sapiens | Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. | Serum | Protein | CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips | Exosomes | EVs |
570 | Vesiclepedia_474 | 23056502 | Homo sapiens | Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. | Melanoma cells | miRNA | - | Exosomes | EVs |
571 | Vesiclepedia_896 | 26100252 | Homo sapiens | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts | Chronic lymphocytic leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
572 | Vesiclepedia_3129 | 34500436 | Homo sapiens | MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
573 | Vesiclepedia_2250 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
574 | Vesiclepedia_2278 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
575 | Vesiclepedia_1073 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
576 | Vesiclepedia_3555 | 24398677 | Homo sapiens | Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer | Serum | dsDNA | Ultracentrifugation | Exosomes | Small EVs |
577 | Vesiclepedia_2488 | 34388111 | Homo sapiens | miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis | Monocytic leukemia cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
578 | Vesiclepedia_3 | 10545503 | Mus musculus | Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73. | Dendritic cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
579 | Vesiclepedia_26 | 19109410 | Mus musculus | Proteomic and immunologic analyses of brain tumor exosomes. | Brain cancer cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
580 | Vesiclepedia_1081 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
581 | Vesiclepedia_2761 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
582 | Vesiclepedia_540 | 23886663 | Homo sapiens | LRRK2 Secretion in Exosomes is Regulated by 14-3-3. | Urine | Protein | - | Exosomes/Microvesicles | EVs |
583 | Vesiclepedia_1451 | 31949130 | Homo sapiens | circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma | Serum | circRNA | Total Exosome Isolation Kit | Exosomes | Small EVs |
584 | Vesiclepedia_3047 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Monocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
585 | Vesiclepedia_3408 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
586 | Vesiclepedia_2977 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Iodixanol density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
587 | Vesiclepedia_1662 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | T lymphocytes |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
588 | Vesiclepedia_68 | 19619303 | Homo sapiens | Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. | Plasma | Protein | Differential centrifugation | Exosomes | EVs |
589 | Vesiclepedia_410 | 20052414 | Homo sapiens | Nanostructural and transcriptomic analyses of human saliva derived exosomes. | Saliva | mRNA | - | Exosomes/Membrane vesicles | EVs |
590 | Vesiclepedia_2768 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Polyethylene glycol-based precipitation |
Exosomes | Small EVs |
591 | Vesiclepedia_2970 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
592 | Vesiclepedia_2631 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
593 | Vesiclepedia_3029 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
594 | Vesiclepedia_753 | 29963269 | Homo sapiens | Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury | Hepatoma cells | miRNA | Total Exosome Isolation Kit Differential centrifugation |
Exosomes | EVs |
595 | Vesiclepedia_477 | 23056502 | Homo sapiens | Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. | Melanoma cells | mRNA | - | Exosomes | EVs |
596 | Vesiclepedia_118 | 21362503 | Homo sapiens | Protein profile of exosomes from trabecular meshwork cells. | Tabecular meshwork cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
597 | Vesiclepedia_116 | 21505438 | Homo sapiens | Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. | B cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
598 | Vesiclepedia_2427 | 35939247 | Homo sapiens | Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
599 | Vesiclepedia_92 | 20124479 | Rattus norvegicus | Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. | Pancreatic cancer cells |
Protein mRNA |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
600 | Vesiclepedia_1544 | 33767144 | Homo sapiens | Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells | Cervical cancer cells | Protein | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
601 | Vesiclepedia_56 | 12147373 | Homo sapiens | Malignant effusions and immunogenic tumour-derived exosomes. | Ascites | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
602 | Vesiclepedia_37 | 10878338 | Homo sapiens | Direct immunosuppressive effects of EBV-encoded latent membrane protein 1. | B cells | Protein | Differential centrifugation | Exosomes | EVs |
603 | Vesiclepedia_815 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
604 | Vesiclepedia_2244 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
605 | Vesiclepedia_40 | 15908444 | Homo sapiens | Exosomal-like vesicles are present in human blood plasma. | Plasma | Protein | Differential centrifugation Filtration Sucrose density gradient |
Exosomes | EVs |
606 | Vesiclepedia_3066 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic duct epithelial cells | Protein | Total Exosome isolation Kit | Exosomes | EVs |
607 | Vesiclepedia_507 | 23511837 | Homo sapiens | Differential protein profiling of renal cell carcinoma urinary exosomes. | Urine | Protein | - | Exosomes/Nanovesicles | EVs |
608 | Vesiclepedia_769 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
609 | Vesiclepedia_2697 | 35210436 | Homo sapiens | M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway | Macrophage | mRNA | Total Exosome Isolation Reagent | Exosomes | Small EVs |
610 | Vesiclepedia_1678 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography |
Exosomes | Small EVs |
611 | Vesiclepedia_2524 | 34315885 | Homo sapiens | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease | Urine | Protein | Centrifugation Ultracentrifugation |
Exosomes | Small EVs |
612 | Vesiclepedia_806 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
613 | Vesiclepedia_2443 | 34489604 | Mus musculus | Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 | Hepatocytes |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
614 | Vesiclepedia_2667 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
615 | Vesiclepedia_3030 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
616 | Vesiclepedia_3069 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Serum | Protein | Total Exosome isolation Kit | Exosomes | EVs |
617 | Vesiclepedia_136 | 22723089 | Homo sapiens | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. | Prostate cancer cells | Protein | Sucrose density gradient | Exosomes | EVs |
618 | Vesiclepedia_1833 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
619 | Vesiclepedia_52 | 14975938 | Homo sapiens | Proteomic analysis of exosomes isolated from human malignant pleural effusions. | Malignant pleural effusions | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
620 | Vesiclepedia_97 | 21828046 | Rattus norvegicus | The proteo-lipidic composition of exosomes changes during reticulocyte maturation. | Reticulocytes |
Protein Lipids |
Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
621 | Vesiclepedia_3143 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Plasma | miRNA | ExoQuick Kit | Exosomes | EVs |
622 | Vesiclepedia_902 | 26100252 | Homo sapiens | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts | Chronic lymphocytic leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
623 | Vesiclepedia_390 | 19158352 | Homo sapiens | Characterization of PKD protein-positive exosome-like vesicles. | Urine | Protein | - | Exosomes/Membrane particles | EVs |
624 | Vesiclepedia_827 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
625 | Vesiclepedia_3048 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Glial cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
626 | Vesiclepedia_3398 | 31054213 | Homo sapiens | Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma | Cholangiocarcinoma cells | Protein | Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
627 | Vesiclepedia_1007 | 23463506 | Mus musculus | The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. | T cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
628 | Vesiclepedia_2771 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Phosphatidylserine affinity purification |
Exosomes | Small EVs |
629 | Vesiclepedia_2254 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
630 | Vesiclepedia_1538 | 33658392 | Homo sapiens | Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma | Lung cancer cells |
Protein miRNA |
Minute High-Efficiency Exosome Precipitation Reagent Filtration |
Exosomes | Small EVs |
631 | Vesiclepedia_1093 | 25065644 | Homo sapiens | Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. | Duodenal cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration |
Exosomes | EVs |
632 | Vesiclepedia_492 | 23333927 | Homo sapiens | Characterization and proteomic analysis of ovarian cancer-derived exosomes. | Ovarian cancer cells | Protein | - | Exosomes | EVs |
633 | Vesiclepedia_537 | 23818640 | Homo sapiens | Modulation of B-cell exosome proteins by gamma herpesvirus infection. | B cells | Protein | - | Exosomes/Microvesicles/Oncosomes/Microparticles | EVs |
634 | Vesiclepedia_675 | 29951053 | Mus musculus | Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. | Myeloid-derived suppressor cells | Protein | Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
635 | Vesiclepedia_482 | 23161513 | Homo sapiens | Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. | Colorectal cancer cells | Protein | - | Exosomes | EVs |
636 | Vesiclepedia_922 | 25483805 | Homo sapiens | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties | Embryonic kidney cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
637 | Vesiclepedia_1542 | 33767144 | Homo sapiens | Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells | Cervical cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
638 | Vesiclepedia_447 | 22444574 | Homo sapiens | Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry. | Saliva | Protein | - | Exosomes/Microvesicles | EVs |
639 | Vesiclepedia_1525 | 33911067 | Homo sapiens | Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis | Serum | circRNAs | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
640 | Vesiclepedia_2969 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
641 | Vesiclepedia_3008 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
642 | Vesiclepedia_1684 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
643 | Vesiclepedia_2754 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
644 | Vesiclepedia_430 | 21595033 | Homo sapiens | Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. | Urine | Protein | - | Exosomes | EVs |
645 | Vesiclepedia_2661 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
646 | Vesiclepedia_437 | 22106071 | Homo sapiens | Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). | Urine | Protein | - | Exosomes/Membrane vesicles | EVs |
647 | Vesiclepedia_112 | 21601258 | Homo sapiens | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. | Serum |
Protein miRNA |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
648 | Vesiclepedia_1118 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
649 | Vesiclepedia_1936 | 36103526 | Homo sapiens | Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases | Hepatic stellate cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
650 | Vesiclepedia_756 | 28357077 | Mus musculus | Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells | Plasma | miRNA | Total Exosome Isolation Kit Differential centrifugation |
Exosomes | EVs |
651 | Vesiclepedia_3395 | 31792209 | Homo sapiens | Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
652 | Vesiclepedia_676 | 29951053 | Mus musculus | Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. | Myeloid-derived suppressor cells | Protein | Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
653 | Vesiclepedia_2473 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
654 | Vesiclepedia_916 | 28687758 | Sus scrofa | Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers | Polarised retinal pigmented epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
655 | Vesiclepedia_3120 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Kidney cells | Protein | Differential centrifugation Filtration Sucrose density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
656 | Vesiclepedia_1809 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
657 | Vesiclepedia_355 | 24115447 | Homo sapiens | Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma | Plasma | Protein | Differential centrifugation Filtration Ultracentrifugation Immunoaffinity (EpCAM) |
Exosomes | EVs |
658 | Vesiclepedia_106 | 21763319 | Homo sapiens | Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. | Pancreatic cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration Ultracentrifugation |
Exosomes | EVs |
659 | Vesiclepedia_1461 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
660 | Vesiclepedia_1048 | 28725021 | Bos taurus | Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. | Bovine milk | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
661 | Vesiclepedia_2639 | 35649370 | Homo sapiens | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Cervical cancer cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
662 | Vesiclepedia_1269 | 24218614 | Homo sapiens | Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
663 | Vesiclepedia_913 | 28687758 | Sus scrofa | Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers | Polarised retinal pigmented epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
664 | Vesiclepedia_346 | 22965126 | Mus musculus | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. | Neuronal cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
665 | Vesiclepedia_2332 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
666 | Vesiclepedia_105 | 21763319 | Homo sapiens | Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. | Pancreatic cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration Ultracentrifugation |
Exosomes | EVs |
667 | Vesiclepedia_3082 | 33827783 | Mus musculus | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic duct epithelial cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
668 | Vesiclepedia_1051 | 29115712 | Mus musculus | Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
669 | Vesiclepedia_1137 | 23861904 | Homo sapiens | Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. | Placental mesenchymal stem cells | Protein | Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation |
Exosomes | EVs |
670 | Vesiclepedia_2618 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
671 | Vesiclepedia_2971 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
672 | Vesiclepedia_2985 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
673 | Vesiclepedia_959 | 26196085 | Homo sapiens | Identification of prostate cancer biomarkers in urinary exosomes. | Urine | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
674 | Vesiclepedia_128 | 14965343 | Homo sapiens | Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization | Dendritic cells | Lipids | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
675 | Vesiclepedia_545 | 23983189 | Homo sapiens | Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. | B cells | Protein | - | Exosomes/Extracellular vesicles/Microvesicles | EVs |
676 | Vesiclepedia_2750 | 35173168 | Homo sapiens | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
677 | Vesiclepedia_1203 | 27780738 | Homo sapiens | Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. | Serum | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
678 | Vesiclepedia_784 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
679 | Vesiclepedia_783 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
680 | Vesiclepedia_789 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
681 | Vesiclepedia_3065 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Serum | Protein | Total Exosome isolation Kit | Exosomes | EVs |
682 | Vesiclepedia_2489 | 34388111 | Homo sapiens | miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis | Monocytic leukemia cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
683 | Vesiclepedia_1814 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum | miRNA | ExoQuick Kit | Exosomes | Small EVs |
684 | Vesiclepedia_1152 | 22057275 | Homo sapiens | Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. | Neuroblastoma cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
685 | Vesiclepedia_100 | 21828046 | Rattus norvegicus | The proteo-lipidic composition of exosomes changes during reticulocyte maturation. | Reticulocytes |
Protein Lipids |
Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
686 | Vesiclepedia_1124 | 24347249 | Homo sapiens | Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation ExoQuick |
Exosomes | EVs |
687 | Vesiclepedia_1333 | 33368224 | Homo sapiens | Colorectal cancer prompted adipose tissue browning and cancer cachexia through transferring exosomal miR-146b-5p | Intestinal epithelial cells |
Protein mRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
688 | Vesiclepedia_1433 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
689 | Vesiclepedia_2442 | 34489604 | Mus musculus | Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 | Hepatocytes |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
690 | Vesiclepedia_1690 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Pancreatic cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
691 | Vesiclepedia_1328 | 33431899 | Mus musculus | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Plasma | Lipid | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
692 | Vesiclepedia_1674 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
693 | Vesiclepedia_3580 | 26530043 | Homo sapiens | Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression | Serum | mtDNA-mutated | ExoQuick exosome precipitation solution | Exosomes | Small EVs |
694 | Vesiclepedia_345 | 22965126 | Mus musculus | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. | Neuronal cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
695 | Vesiclepedia_3056 | 33827783 | Mus musculus | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
696 | Vesiclepedia_16 | 9685355 | Homo sapiens | Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. | B cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
697 | Vesiclepedia_2630 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
698 | Vesiclepedia_3401 | 31054213 | Homo sapiens | Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma | Cholangiocarcinoma cells | Protein | Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
699 | Vesiclepedia_535 | 23818640 | Homo sapiens | Modulation of B-cell exosome proteins by gamma herpesvirus infection. | B cells | Protein | - | Exosomes/Microvesicles/Oncosomes/Microparticles | EVs |
700 | Vesiclepedia_1463 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
701 | Vesiclepedia_812 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
702 | Vesiclepedia_1075 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
703 | Vesiclepedia_2339 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
704 | Vesiclepedia_60 | 17700640 | Mus musculus | CD24 is a marker of exosomes secreted into urine and amniotic fluid. | Urine | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
705 | Vesiclepedia_963 | 25844599 | Homo sapiens | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
706 | Vesiclepedia_187 | 22116803 | Equus caballus | Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle | Serum | Protein | Differential centrifugation ExoQuick |
Exosomes | EVs |
707 | Vesiclepedia_1469 | 32132543 | Homo sapiens | Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension | Pulmonary artery endothelial cells | miRNA | miRCURY Exosome Isolation Kit Centrifugation Sonication |
Exosomes | Small EVs |
708 | Vesiclepedia_987 | 25261472 | Homo sapiens | Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes/Microvesicles | EVs |
709 | Vesiclepedia_1327 | 33431899 | Mus musculus | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Plasma | Lipid | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
710 | Vesiclepedia_2337 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Plasma | miRNA | ExoQuick Kit Centrifugation |
Exosomes | Small EVs |
711 | Vesiclepedia_1121 | 24347249 | Homo sapiens | Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation ExoQuick |
Exosomes | EVs |
712 | Vesiclepedia_2004 | 34112803 | Mus musculus | Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Centrifugal ultrafiltration |
Exosomes | Small EVs |
713 | Vesiclepedia_388 | 18570454 | Homo sapiens | Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry. | Neural stem cells | Protein | - | Exosomes/Membrane vesicles | EVs |
714 | Vesiclepedia_2277 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
715 | Vesiclepedia_3269 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
716 | Vesiclepedia_1828 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells |
Protein miRNA |
Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
717 | Vesiclepedia_2625 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
718 | Vesiclepedia_1104 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
719 | Vesiclepedia_69 | 19812188 | Rattus norvegicus | Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII. | Dendritic cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
720 | Vesiclepedia_1934 | 36103526 | Homo sapiens | Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases | Hepatic stellate cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
721 | Vesiclepedia_1680 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
722 | Vesiclepedia_1157 | 20662102 | Mus musculus | Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages. | Macrophage | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
723 | Vesiclepedia_760 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
724 | Vesiclepedia_3399 | 31054213 | Homo sapiens | Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma | Cholangiocarcinoma cells | Protein | Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
725 | Vesiclepedia_1530 | 33752173 | Homo sapiens | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression | Breast cancer cells | miRNA | Total Exosome Isolation Kit Centrifugation |
Exosomes | Small EVs |
726 | Vesiclepedia_838 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
727 | Vesiclepedia_2613 | 35443745 | Homo sapiens | Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts | Colorectal cancer cells |
Protein miRNA |
Ultracentrifugation ExoQuick Kit |
Exosomes | Small EVs |
728 | Vesiclepedia_2335 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
729 | Vesiclepedia_724 | 25471207 | Homo sapiens | Intraluminal proteome and peptidome of human urinary extracellular vesicles. | Urine | Protein | Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration |
Exosomes | EVs |
730 | Vesiclepedia_1020 | 21734072 | Mus musculus | Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice. | Insulinoma cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
731 | Vesiclepedia_1660 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Pancreatic duct epithelial cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
732 | Vesiclepedia_2607 | 36581340 | Homo sapiens | Rab27b, a Regulator of Exosome Secretion, Is Associated With Peritoneal Metastases in Gastric Cancer | Gastric cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
733 | Vesiclepedia_2469 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
734 | Vesiclepedia_411 | 20124223 | Homo sapiens | Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. | Squamous carcinoma cells | Protein | - | Exosomes | EVs |
735 | Vesiclepedia_2463 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
736 | Vesiclepedia_1368 | 32132711 | Mus musculus | Decoy exosomes provide protection against bacterial toxins | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
737 | Vesiclepedia_826 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
738 | Vesiclepedia_2669 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
739 | Vesiclepedia_3070 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
740 | Vesiclepedia_2242 | 36648227 | Mus musculus | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Macrophage | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
741 | Vesiclepedia_94 | 21828046 | Rattus norvegicus | The proteo-lipidic composition of exosomes changes during reticulocyte maturation. | Reticulocytes |
Protein Lipids |
Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
742 | Vesiclepedia_2445 | 34489604 | Mus musculus | Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 | Hepatocytes |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
743 | Vesiclepedia_2991 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
744 | Vesiclepedia_1216 | 27872147 | Rattus norvegicus | Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. | Islets | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
745 | Vesiclepedia_3068 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Serum | Protein | Total Exosome isolation Kit | Exosomes | EVs |
746 | Vesiclepedia_550 | 24009881 | Homo sapiens | Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. | Colorectal cancer cells | Protein | - | Exosomes/Extracellular vesicles/Microvesicles/Ectosomes | EVs |
747 | Vesiclepedia_3112 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Hippocampal neuronal cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
748 | Vesiclepedia_3057 | 33827783 | Mus musculus | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
749 | Vesiclepedia_1149 | 22807456 | Homo sapiens | Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells. | Lymphocytes | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
750 | Vesiclepedia_667 | 29956871 | Homo sapiens | Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis | Bronchoalveolar lavage fluid | miRNA | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
751 | Vesiclepedia_3271 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
752 | Vesiclepedia_1072 | 29937354 | Homo sapiens | Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. | Glioblastoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
753 | Vesiclepedia_1336 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | Plasma |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
754 | Vesiclepedia_754 | 29963269 | Homo sapiens | Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury | Hepatoma cells | Protein | Total Exosome Isolation Kit Differential centrifugation |
Exosomes | EVs |
755 | Vesiclepedia_62 | 17133577 | Mus musculus | Association of citrullinated proteins with synovial exosomes. | Synovial fluid | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
756 | Vesiclepedia_1695 | 34108659 | Mus musculus | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Colorectal cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
757 | Vesiclepedia_863 | 22046311 | Mus musculus | Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections | Plasma | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
758 | Vesiclepedia_1533 | 33589572 | Homo sapiens | Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis | Plasma |
Protein lncRNA |
Centrifugation ExoQuick Kit |
Exosomes | Small EVs |
759 | Vesiclepedia_122 | 21235781 | Homo sapiens | Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. | Saliva | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
760 | Vesiclepedia_2973 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
761 | Vesiclepedia_2916 | 26061593 | Homo sapiens | Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
762 | Vesiclepedia_1653 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Glioblastoma cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
763 | Vesiclepedia_19 | 16302729 | Homo sapiens | Purification, characterization and biological significance of tumor-derived exosomes. | Breast cancer cells | Protein | Differential centrifugation Sucrose density gradient Filtration Immunobeads(HER2) |
Exosomes | EVs |
764 | Vesiclepedia_2325 | 31807237 | Homo sapiens | Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
765 | Vesiclepedia_2649 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
766 | Vesiclepedia_1568 | 33738083 | Homo sapiens | Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
767 | Vesiclepedia_2241 | 36648227 | Mus musculus | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Macrophage | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
768 | Vesiclepedia_763 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
769 | Vesiclepedia_1014 | 22711894 | Homo sapiens | Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. | Macrophage |
Protein Lipids |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
770 | Vesiclepedia_1996 | 34112803 | Mus musculus | Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Centrifugal ultrafiltration |
Exosomes | Small EVs |
771 | Vesiclepedia_3012 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
772 | Vesiclepedia_1468 | 32132543 | Homo sapiens | Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension | Pulmonary artery endothelial cells | miRNA | miRCURY Exosome Isolation Kit Centrifugation Sonication |
Exosomes | Small EVs |
773 | Vesiclepedia_1017 | 22711894 | Homo sapiens | Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. | Macrophage |
Protein Lipids |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
774 | Vesiclepedia_2915 | 26061593 | Homo sapiens | Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
775 | Vesiclepedia_3144 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Plasma | miRNA | ExoQuick Kit | Exosomes | EVs |
776 | Vesiclepedia_766 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
777 | Vesiclepedia_3568 | 27684368 | Homo sapiens | Indication of Horizontal DNA Gene Transfer by Extracellular Vesicles | Mesenchymal stem cells | dsDNA | Differential centrifugation Ultracentrifugation |
Exosomes|Microvesicles | EVs |
778 | Vesiclepedia_1686 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Pancreatic cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography |
Exosomes | Small EVs |
779 | Vesiclepedia_2760 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
780 | Vesiclepedia_929 | 25483805 | Gallus gallus | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties | Notochord cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
781 | Vesiclepedia_1656 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Glioblastoma cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
782 | Vesiclepedia_1005 | 23463506 | Homo sapiens | The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. | T cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
783 | Vesiclepedia_735 | 25285581 | Mus musculus | Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells. | Myeloid-derived suppressor cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
784 | Vesiclepedia_3164 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
785 | Vesiclepedia_1447 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
786 | Vesiclepedia_2422 | 35939247 | Homo sapiens | Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
787 | Vesiclepedia_1694 | 34108659 | Mus musculus | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Melanoma cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
788 | Vesiclepedia_1679 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
789 | Vesiclepedia_7 | 12626558 | Mus musculus | Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. | Mast cells | Protein | Differential centrifugation | Exosomes | EVs |
790 | Vesiclepedia_658 | 28753793 | Homo sapiens | MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma. | Serum | miRNA | Total Exosome Isolation Kit Differential centrifugation Ultracentrifugation Immunobeads (EpCAM) |
Exosomes | EVs |
791 | Vesiclepedia_451 | 22451062 | Homo sapiens | A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: application to RCC urinary exosomes. | Urine | Lipids | - | Exosomes | EVs |
792 | Vesiclepedia_1699 | 34108659 | Bos taurus | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Serum | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
793 | Vesiclepedia_131 | 19188015 | Homo sapiens | Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes | Ascites |
Protein Lipids |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
794 | Vesiclepedia_2694 | 35210436 | Homo sapiens | M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway | Macrophage |
Protein mRNA |
Total Exosome Isolation Reagent | Exosomes | Small EVs |
795 | Vesiclepedia_1106 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
796 | Vesiclepedia_96 | 21828046 | Rattus norvegicus | The proteo-lipidic composition of exosomes changes during reticulocyte maturation. | Reticulocytes |
Protein Lipids |
Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
797 | Vesiclepedia_761 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
798 | Vesiclepedia_1681 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
799 | Vesiclepedia_1283 | 22345510 | Rattus norvegicus | Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. | Insulinoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
800 | Vesiclepedia_2664 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
801 | Vesiclepedia_2763 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
802 | Vesiclepedia_50 | 14582906 | Homo sapiens | Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. | Dendritic cells | Protein | Differential centrifugation Immunobeads (EpCAM) |
Exosomes | EVs |
803 | Vesiclepedia_109 | 21601258 | Homo sapiens | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. | Malignant pleural effusions |
Protein miRNA |
Differential centrifugation Sucrose density gradient Immunobeads (EpCAM) |
Exosomes | EVs |
804 | Vesiclepedia_146 | 22723089 | Homo sapiens | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. | Prostate cancer cells | Protein | Sucrose density gradient | Exosomes | EVs |
805 | Vesiclepedia_1046 | 28725021 | Bos taurus | Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. | Bovine milk | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
806 | Vesiclepedia_1097 | 24513287 | Mus musculus | Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. | adipocytes | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
807 | Vesiclepedia_865 | 22046311 | Mus musculus | Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections | Reticulocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
808 | Vesiclepedia_73 | 18494037 | Mus musculus | Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes. | Embryonic fibroblasts | Protein | Differential centrifugation | Exosomes | EVs |
809 | Vesiclepedia_2341 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
810 | Vesiclepedia_1813 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum | miRNA | ExoQuick Kit | Exosomes | Small EVs |
811 | Vesiclepedia_27 | 19109410 | Homo sapiens | Proteomic and immunologic analyses of brain tumor exosomes. | Medulloblastoma cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
812 | Vesiclepedia_2251 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
813 | Vesiclepedia_1234 | 25421927 | Mus musculus | Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. | Serum |
miRNA Protein |
Filtration Ultracentrifugation |
Exosomes | EVs |
814 | Vesiclepedia_43 | 17076679 | Homo sapiens | Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences. | Plasma | Protein | Size exclusion chromatography Ultracentrifugation Immunobeads (CD3, CD19, CD56, CD83, PLAP) |
Exosomes | EVs |
815 | Vesiclepedia_38 | 15210972 | Oryctolagus cuniculus | Cells release prions in association with exosomes. | Epithelial cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
816 | Vesiclepedia_1197 | 27883272 | Homo sapiens | Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. | Plasma |
miRNA Metabolites |
ExoQuick | Exosomes | EVs |
817 | Vesiclepedia_3107 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Hippocampal neuronal cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
818 | Vesiclepedia_1432 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
819 | Vesiclepedia_674 | 29953960 | Homo sapiens | Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. | Macrophage | Protein | Microfiltration Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
820 | Vesiclepedia_3004 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
821 | Vesiclepedia_8 | 12626558 | Mus musculus | Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. | B cells | Protein | Differential centrifugation | Exosomes | EVs |
822 | Vesiclepedia_982 | 25458527 | Homo sapiens | Benchtop isolation and characterization of functional exosomes by sequential filtration | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
823 | Vesiclepedia_2472 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
824 | Vesiclepedia_2698 | 35210436 | Homo sapiens | M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway | Macrophage | mRNA | Total Exosome Isolation Reagent | Exosomes | Small EVs |
825 | Vesiclepedia_1438 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
826 | Vesiclepedia_539 | 23853596 | Trichomonas vaginalis | Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions. | Trichomonas vaginalis | Protein | - | Exosomes/Microvesicles | EVs |
827 | Vesiclepedia_1675 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
828 | Vesiclepedia_1998 | 34112803 | Homo sapiens | Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Centrifugal ultrafiltration |
Exosomes | Small EVs |
829 | Vesiclepedia_3285 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
830 | Vesiclepedia_2741 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
831 | Vesiclepedia_3117 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Brain | Protein | Differential centrifugation Filtration Sucrose density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
832 | Vesiclepedia_2654 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
833 | Vesiclepedia_3126 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Kidney cells | Protein | Differential centrifugation Filtration Sucrose density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
834 | Vesiclepedia_190 | 22116803 | Equus caballus | Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle | Follicular fluid | miRNA | Differential centrifugation ExoQuick |
Exosomes | EVs |
835 | Vesiclepedia_1441 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
836 | Vesiclepedia_1126 | 24295599 | Mus musculus | Exosomes from myeloid-derived suppressor cells carry biologically active proteins. | Myeloid-derived suppressor cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
837 | Vesiclepedia_347 | 22285593 | Homo sapiens | Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. | Colorectal cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
838 | Vesiclepedia_95 | 21828046 | Rattus norvegicus | The proteo-lipidic composition of exosomes changes during reticulocyte maturation. | Reticulocytes |
Protein Lipids |
Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
839 | Vesiclepedia_2236 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
840 | Vesiclepedia_1119 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
841 | Vesiclepedia_439 | 22129587 | Bos taurus | Bovine milk exosome proteome. | Bovine milk | Protein | - | Exosomes/Membrane vesicles | EVs |
842 | Vesiclepedia_1107 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
843 | Vesiclepedia_113 | 21557262 | Homo sapiens | Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. | Urine | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
844 | Vesiclepedia_12 | 15478216 | Homo sapiens | Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry. | Melanoma cells | Protein | Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
845 | Vesiclepedia_332 | 19627513 | Homo sapiens | Exosomes from human saliva as a source of microRNA biomarkers | Saliva | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
846 | Vesiclepedia_1437 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
847 | Vesiclepedia_1816 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum | miRNA | ExoQuick Kit | Exosomes | Small EVs |
848 | Vesiclepedia_5 | 11145662 | Mus musculus | Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes. | Mast cells | Protein | Differential centrifugation | Exosomes | EVs |
849 | Vesiclepedia_2601 | 35351860 | Homo sapiens | Bone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5 | Bone marrow mesenchymal stem cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
850 | Vesiclepedia_2996 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
851 | Vesiclepedia_3199 | 34690112 | Homo sapiens | Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling | Ovarian cancer cells | Protein | ExoQuick Kit | Exosomes | EVs |
852 | Vesiclepedia_752 | 29963269 | Homo sapiens | Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury | Hepatoma cells | Protein | Total Exosome Isolation Kit Differential centrifugation |
Exosomes | EVs |
853 | Vesiclepedia_2328 | 31807237 | Homo sapiens | Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
854 | Vesiclepedia_1019 | 21734072 | Mus musculus | Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice. | Insulinoma cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
855 | Vesiclepedia_534 | 23818640 | Homo sapiens | Modulation of B-cell exosome proteins by gamma herpesvirus infection. | B cells | Protein | - | Exosomes/Microvesicles/Oncosomes/Microparticles | EVs |
856 | Vesiclepedia_2229 | 36648227 | Mus musculus | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Macrophage | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
857 | Vesiclepedia_3075 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
858 | Vesiclepedia_1689 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Pancreatic cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
859 | Vesiclepedia_1450 | 31949130 | Homo sapiens | circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma | Serum | circRNA | Total Exosome Isolation Kit | Exosomes | Small EVs |
860 | Vesiclepedia_114 | 21557262 | Homo sapiens | Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. | Urine | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
861 | Vesiclepedia_145 | 22723089 | Homo sapiens | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. | Prostate cancer cells | Protein | Sucrose density gradient | Exosomes | EVs |
862 | Vesiclepedia_2744 | 35173168 | Mus musculus | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
863 | Vesiclepedia_2027 | 36455873 | Homo sapiens | Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF | Plasma |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
864 | Vesiclepedia_2237 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
865 | Vesiclepedia_881 | 29955024 | Homo sapiens | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells | Myeloid leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
866 | Vesiclepedia_1526 | 33479185 | Homo sapiens | Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke | Mesenchymal stem cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
867 | Vesiclepedia_2988 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
868 | Vesiclepedia_2500 | 34329193 | Homo sapiens | CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis | Breast cancer cells | miRNA | Total Exosome Isolation Reagent | Exosomes | EVs |
869 | Vesiclepedia_357 | 24352158 | Homo sapiens | Characterization and deep sequencing analysis of exosomal miRNA in human urine | Urine | miRNA | Differential centrifugation Norgen Biotek Exosome kit |
Exosomes | EVs |
870 | Vesiclepedia_781 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
871 | Vesiclepedia_3140 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Plasma |
Protein miRNA |
ExoQuick Kit | Exosomes | EVs |
872 | Vesiclepedia_801 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
873 | Vesiclepedia_2002 | 34112803 | Homo sapiens | Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution | Plasma | Protein | Size exclusion chromatography Centrifugal ultrafiltration |
Exosomes | Small EVs |
874 | Vesiclepedia_2653 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
875 | Vesiclepedia_3152 | 34887361 | Mus musculus | Endothelial cell-derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway | Endothelial cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
876 | Vesiclepedia_2749 | 35173168 | Homo sapiens | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
877 | Vesiclepedia_67 | 19619303 | Homo sapiens | Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. | Ovarian cancer cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
878 | Vesiclepedia_2650 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
879 | Vesiclepedia_1162 | 22641613 | Homo sapiens | Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. | Urine | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
880 | Vesiclepedia_1287 | 20880880 | Homo sapiens | Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis. | Bronchoalveolar lavage fluid | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
881 | Vesiclepedia_478 | 23082778 | Homo sapiens | Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. | Urine | Protein | - | Exosomes/Membrane vesicles | EVs |
882 | Vesiclepedia_3154 | 34789738 | Homo sapiens | P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells | Melanoma cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
883 | Vesiclepedia_976 | 22808001 | Homo sapiens | Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. | Serum | Protein | Filtration ExoQuick |
Exosomes | EVs |
884 | Vesiclepedia_513 | 23533145 | Homo sapiens | In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. | Urine | Protein | - | Exosomes/Microvesicles | EVs |
885 | Vesiclepedia_828 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
886 | Vesiclepedia_1528 | 33752173 | Homo sapiens | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
887 | Vesiclepedia_2323 | 31762962 | Homo sapiens | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers | Monocytes | miRNA | Cell culture media exosome purification and RNA isolation Kit | Exosomes | Small EVs |
888 | Vesiclepedia_3200 | 34690112 | Homo sapiens | Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling | Ovarian cancer cells | Protein | ExoQuick Kit | Exosomes | EVs |
889 | Vesiclepedia_824 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
890 | Vesiclepedia_2234 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
891 | Vesiclepedia_1566 | 33523942 | Homo sapiens | Exosomal delivery of NF-κB inhibitor delays LPS-induced preterm birth and modulates fetal immune cell profile in mouse models | Embryonic kidney cells | Protein | Centrifugation Filtration Size exclusion chromatography |
Exosomes | Small EVs |
892 | Vesiclepedia_340 | 20615901 | Homo sapiens | Export of microRNAs and microRNA-protective protein by mammalian cells | Lung cancer cells | miRNA | Differential centrifugation | Exosomes | EVs |
893 | Vesiclepedia_59 | 17700640 | Mus musculus | CD24 is a marker of exosomes secreted into urine and amniotic fluid. | Amniotic fluid | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
894 | Vesiclepedia_3277 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
895 | Vesiclepedia_3380 | 31848325 | Rattus norvegicus | Insulin-like growth factor-1 enchances neuroprotective effects of neural stem cell exosomes after spinal cord injury via an miR-219a-2-3p/YY1 mechanism | Neural stem cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
896 | Vesiclepedia_817 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
897 | Vesiclepedia_199 | 21609964 | Homo sapiens | Characterization of extracellular circulating microRNA | Plasma | Protein | Differential centrifugation Filtration |
Exosomes | EVs |
898 | Vesiclepedia_133 | 19188015 | Homo sapiens | Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes | Ovarian cancer cells |
Protein Lipids |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
899 | Vesiclepedia_548 | 24009880 | Homo sapiens | Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. | Mast cells | mRNA | - | Exosomes/Extracellular vesicles | EVs |
900 | Vesiclepedia_392 | 19351151 | Mus musculus | Characterization of vesicles secreted from insulinoma NIT-1 cells. | Pancreatic cells | Protein | - | Exosomes | EVs |
901 | Vesiclepedia_830 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
902 | Vesiclepedia_1687 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Pancreatic cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
903 | Vesiclepedia_811 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
904 | Vesiclepedia_3067 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Total Exosome isolation Kit | Exosomes | EVs |
905 | Vesiclepedia_129 | 14965343 | Rattus norvegicus | Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization | Tumoral mast cells | Lipids | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
906 | Vesiclepedia_3145 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Plasma | miRNA | ExoQuick Kit | Exosomes | EVs |
907 | Vesiclepedia_3134 | 34500436 | Homo sapiens | MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
908 | Vesiclepedia_2626 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
909 | Vesiclepedia_1444 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
910 | Vesiclepedia_82 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Stomach cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
911 | Vesiclepedia_479 | 23082778 | Homo sapiens | Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. | Urine | Protein | - | Exosomes/Membrane vesicles | EVs |
912 | Vesiclepedia_1693 | 34108659 | Mus musculus | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
913 | Vesiclepedia_398 | 19530224 | Homo sapiens | Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. | Keratinocytes | Protein | - | Exosomes | EVs |
914 | Vesiclepedia_1666 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Breast cancer cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
915 | Vesiclepedia_483 | 23214914 | Trypanosoma cruzi | Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. | Epimastigotes | Protein | - | Exosomes/Extracellular vesicles/Ectosomes | EVs |
916 | Vesiclepedia_947 | 28819550 | Mus musculus | Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses. | Bronchoalveolar lavage fluid | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
917 | Vesiclepedia_1823 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Serum | miRNA | Total Exosome Isolation Kit | Exosomes | Small EVs |
918 | Vesiclepedia_1122 | 24347249 | Homo sapiens | Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation ExoQuick |
Exosomes | EVs |
919 | Vesiclepedia_1670 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Monocytic leukemia cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
920 | Vesiclepedia_342 | 22965126 | Mus musculus | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. | Neuronal cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
921 | Vesiclepedia_1524 | 33911067 | Homo sapiens | Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis | Serum | circRNAs | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
922 | Vesiclepedia_2655 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
923 | Vesiclepedia_476 | 23056502 | Homo sapiens | Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. | Melanoma cells | miRNA | - | Exosomes | EVs |
924 | Vesiclepedia_762 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
925 | Vesiclepedia_3063 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Serum | Protein | Total Exosome isolation Kit | Exosomes | EVs |
926 | Vesiclepedia_1045 | 28725021 | Bos taurus | Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. | Bovine milk | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
927 | Vesiclepedia_374 | 18039940 | Cryptococcus neoformans | Extracellular vesicles produced by Cryptococcus neoformans contain protein components associated with virulence. | Cryptococcus neoformans | Protein | - | Exosomes/Extracellular vesicles | EVs |
928 | Vesiclepedia_1467 | 32132543 | Homo sapiens | Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension | Pulmonary artery endothelial cells | Protein | miRCURY Exosome Isolation Kit Centrifugation Sonication |
Exosomes | Small EVs |
929 | Vesiclepedia_2772 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Saliva | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
930 | Vesiclepedia_1136 | 23861904 | Homo sapiens | Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. | Placental mesenchymal stem cells | Protein | Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation |
Exosomes | EVs |
931 | Vesiclepedia_1815 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum | miRNA | ExoQuick Kit | Exosomes | Small EVs |
932 | Vesiclepedia_330 | 20304794 | Homo sapiens | Functional delivery of viral miRNAs via exosomes | B cells | miRNA | Differential centrifugation | Exosomes | EVs |
933 | Vesiclepedia_3250 | 34545097 | Homo sapiens | Exosome-mediated stable epigenetic repression of HIV-1 | Embryonic kidney cells | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
934 | Vesiclepedia_2615 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
935 | Vesiclepedia_2462 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
936 | Vesiclepedia_2981 | 30089911 | Mus musculus | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
937 | Vesiclepedia_1125 | 24347249 | Homo sapiens | Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation ExoQuick |
Exosomes | EVs |
938 | Vesiclepedia_883 | 29955024 | Homo sapiens | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells | Myeloid leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
939 | Vesiclepedia_498 | 23376485 | Homo sapiens | Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. | Urine | Protein | - | Exosomes/Membrane vesicles | EVs |
940 | Vesiclepedia_718 | 26148937 | Homo sapiens | Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. | Cholangiocarcinoma cells | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
941 | Vesiclepedia_3031 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
942 | Vesiclepedia_115 | 21505438 | Homo sapiens | Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. | T cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
943 | Vesiclepedia_3552 | 31555514 | Homo sapiens | Liquid biopsies using pleural effusion-derived exosomal DNA in advanced lung adenocarcinoma | Pleural effusion | dsDNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
944 | Vesiclepedia_780 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
945 | Vesiclepedia_1144 | 23454749 | Homo sapiens | BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. | Bone marrow mesenchymal stromal cells | Protein | Differential centrifugation Ultracentrifugation Filtration ExoQuick |
Exosomes | EVs |
946 | Vesiclepedia_1077 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | miRNA | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
947 | Vesiclepedia_2774 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Saliva | Protein | Filtration Polyethylene glycol-based precipitation |
Exosomes | Small EVs |
948 | Vesiclepedia_2346 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
949 | Vesiclepedia_3543 | 26530043 | Homo sapiens | Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression | Serum | mtDNA | ExoQuick exosome precipitation solution | Exosomes | Small EVs |
950 | Vesiclepedia_15 | 17486113 | Mus musculus Homo sapiens |
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. | Mast cells |
Protein mRNA miRNA |
Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
951 | Vesiclepedia_46 | 17641064 | Homo sapiens | Exosomes with immune modulatory features are present in human breast milk. | Breast milk | Protein | Differential centrifugation Filtration Sucrose density gradient |
Exosomes | EVs |
952 | Vesiclepedia_1123 | 24347249 | Homo sapiens | Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation ExoQuick |
Exosomes | EVs |
953 | Vesiclepedia_2628 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
954 | Vesiclepedia_2910 | 26061593 | Homo sapiens | Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
955 | Vesiclepedia_1259 | 24400796 | Rattus norvegicus | Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. | Retinal glial cells | Protein | ExoQuick | Exosomes | EVs |
956 | Vesiclepedia_1196 | 27883272 | Homo sapiens | Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. | Plasma |
miRNA Metabolites |
ExoQuick | Exosomes | EVs |
957 | Vesiclepedia_1256 | 24400796 | Homo sapiens | Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. | Retinal pigment epithelial cells | Protein | ExoQuick | Exosomes | EVs |
958 | Vesiclepedia_2975 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Iodixanol density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
959 | Vesiclepedia_1500 | 33982667 | Homo sapiens | Exosomal circRNA 0001445 promotes glioma progression through miRNA-127-5p/SNX5 pathway | Glioblastoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
960 | Vesiclepedia_71 | 19801663 | Homo sapiens | Microenvironmental pH is a key factor for exosome traffic in tumor cells. | Melanoma cells |
Protein Lipids |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
961 | Vesiclepedia_1668 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Pluripotent stem cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
962 | Vesiclepedia_2752 | 35173168 | Homo sapiens | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression | Serum | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
963 | Vesiclepedia_671 | 29953960 | Homo sapiens | Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. | Macrophage | Protein | Microfiltration Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
964 | Vesiclepedia_1082 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
965 | Vesiclepedia_1669 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Lymphoma cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
966 | Vesiclepedia_1439 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
967 | Vesiclepedia_124 | 21235781 | Homo sapiens | Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. | Breast milk | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
968 | Vesiclepedia_123 | 21235781 | Homo sapiens | Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. | Plasma | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
969 | Vesiclepedia_797 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
970 | Vesiclepedia_2647 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
971 | Vesiclepedia_2467 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
972 | Vesiclepedia_2658 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
973 | Vesiclepedia_2995 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
974 | Vesiclepedia_337 | 20976003 | Homo sapiens | Selective release of microRNA species from normal and malignant mammary epithelial cells | Breast cancer cells | miRNA | Differential centrifugation Filtration |
Exosomes | EVs |
975 | Vesiclepedia_120 | 21362503 | Homo sapiens | Protein profile of exosomes from trabecular meshwork cells. | Aqueous humor | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
976 | Vesiclepedia_1367 | 32132711 | Mus musculus | Decoy exosomes provide protection against bacterial toxins | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
977 | Vesiclepedia_2420 | 35939247 | Homo sapiens | Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
978 | Vesiclepedia_3127 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Hippocampal neuronal cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
979 | Vesiclepedia_1532 | 33752173 | Homo sapiens | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression | Plasma | miRNA | Total Exosome Isolation Kit Centrifugation |
Exosomes | Small EVs |
980 | Vesiclepedia_755 | 29963269 | Homo sapiens | Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury | Hepatoma cells | miRNA | Total Exosome Isolation Kit Differential centrifugation |
Exosomes | EVs |
981 | Vesiclepedia_2645 | 35649370 | Homo sapiens | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Mammary epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
982 | Vesiclepedia_1022 | 19665478 | Salmo salar | CpG-induced secretion of MHCIIbeta and exosomes from salmon (Salmo salar) APCs. | Head kidney leukocytes | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
983 | Vesiclepedia_436 | 22031862 | Mus musculus | Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. | Dendritic cells | miRNA | - | Exosomes/Nanovesicles | EVs |
984 | Vesiclepedia_1811 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
985 | Vesiclepedia_2605 | 36581340 | Homo sapiens | Rab27b, a Regulator of Exosome Secretion, Is Associated With Peritoneal Metastases in Gastric Cancer | Gastric cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
986 | Vesiclepedia_757 | 28357077 | Mus musculus | Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells | Plasma | miRNA | Total Exosome Isolation Kit Differential centrifugation |
Exosomes | EVs |
987 | Vesiclepedia_1341 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | Muscle | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
988 | Vesiclepedia_453 | 22635005 | Homo sapiens | Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. | Melanoma cells | Protein | - | Exosomes | EVs |
989 | Vesiclepedia_3402 | 31054213 | Homo sapiens | Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma | Cholangiocarcinoma cells | Protein | Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
990 | Vesiclepedia_3124 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Kidney cells | Protein | Differential centrifugation Filtration Sucrose density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
991 | Vesiclepedia_1322 | 33431899 | Mus musculus | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Faeces | Lipid | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
992 | Vesiclepedia_91 | 21252909 | Homo sapiens | Diacylglycerol kinase a regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes | T cells |
Protein Lipids |
Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
993 | Vesiclepedia_1148 | 23173708 | Rattus norvegicus | Wnt3a induces exosome secretion from primary cultured rat microglia. | Primary microglial cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
994 | Vesiclepedia_90 | 21828046 | Rattus norvegicus | The proteo-lipidic composition of exosomes changes during reticulocyte maturation. | Reticulocytes |
Protein Lipids |
Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
995 | Vesiclepedia_2769 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Membrane affinity purification |
Exosomes | Small EVs |
996 | Vesiclepedia_2297 | 29339034 | Homo sapiens | Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer | Pancreatic duct fluid | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
997 | Vesiclepedia_1078 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | miRNA | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
998 | Vesiclepedia_1810 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | ExoQuick Kit | Exosomes | Small EVs |
999 | Vesiclepedia_677 | 29951053 | Mus musculus | Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. | Dendritic cells | Protein | Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1000 | Vesiclepedia_1153 | 22057275 | Homo sapiens | Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. | Neuroblastoma cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1001 | Vesiclepedia_860 | 25776846 | Homo sapiens | Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens | Epithelial cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1002 | Vesiclepedia_2424 | 35939247 | Homo sapiens | Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1003 | Vesiclepedia_1324 | 33431899 | Mus musculus | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Faeces |
Protein Lipid miRNA |
Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
1004 | Vesiclepedia_3252 | 34545097 | Homo sapiens | Exosome-mediated stable epigenetic repression of HIV-1 | Embryonic kidney cells |
Protein mRNA |
Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
1005 | Vesiclepedia_1829 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
1006 | Vesiclepedia_1703 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Plasma | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1007 | Vesiclepedia_488 | 23230278 | Homo sapiens | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. | Colorectal cancer cells | Protein | - | Exosomes/Extracellular vesicles/Microvesicles | EVs |
1008 | Vesiclepedia_1012 | 22711894 | Homo sapiens | Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. | Macrophage | Protein | Differential centrifugation Filtration Ultracentrifugation |
Microvesicles/Exosomes | EVs |
1009 | Vesiclepedia_971 | 22808001 | Homo sapiens | Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. | Serum | Protein | Filtration ExoQuick |
Exosomes | EVs |
1010 | Vesiclepedia_834 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
1011 | Vesiclepedia_3198 | 34690112 | Homo sapiens | Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling | Plasma |
Protein lncRNA |
ExoQuick Kit | Exosomes | EVs |
1012 | Vesiclepedia_1001 | 24079734 | Mus musculus | Immunostimulatory activity of murine keratinocyte-derived exosomes. | Keratinocytes | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1013 | Vesiclepedia_41 | 15908444 | Homo sapiens | Exosomal-like vesicles are present in human blood plasma. | Mast cells | Protein | Differential centrifugation Filtration Sucrose density gradient |
Exosomes | EVs |
1014 | Vesiclepedia_3397 | 31054213 | Homo sapiens | Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma | Cholangiocarcinoma cells | Protein | Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
1015 | Vesiclepedia_3072 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1016 | Vesiclepedia_144 | 22723089 | Homo sapiens | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. | Prostate cancer cells | Protein | Sucrose density gradient | Exosomes | EVs |
1017 | Vesiclepedia_89 | 20424270 | Rattus norvegicus | Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. | Basophilic leukemia cells |
Protein Lipids |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
1018 | Vesiclepedia_911 | 28687758 | Sus scrofa | Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers | Polarised retinal pigmented epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1019 | Vesiclepedia_1006 | 23463506 | Mus musculus | The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. | T cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1020 | Vesiclepedia_1145 | 23173708 | Rattus norvegicus | Wnt3a induces exosome secretion from primary cultured rat microglia. | Primary microglial cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1021 | Vesiclepedia_2657 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1022 | Vesiclepedia_3136 | 34500436 | Homo sapiens | MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1023 | Vesiclepedia_836 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
1024 | Vesiclepedia_74 | 19381331 | Homo sapiens | High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. | Melanoma cells | Protein | Differential centrifugation | Exosomes | EVs |
1025 | Vesiclepedia_22 | 15940614 | Homo sapiens | Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape. | Colorectal cancer cells | Protein | Differential centrifugation | Exosomes | EVs |
1026 | Vesiclepedia_3113 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Hippocampal neuronal cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1027 | Vesiclepedia_3000 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1028 | Vesiclepedia_2976 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Iodixanol density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1029 | Vesiclepedia_3405 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Embryonic cells |
Protein miRNA |
Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
1030 | Vesiclepedia_2914 | 26061593 | Homo sapiens | Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1031 | Vesiclepedia_3080 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1032 | Vesiclepedia_518 | 23585443 | Homo sapiens | Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. | Colorectal cancer cells | Protein | - | Exosomes/Membrane vesicles | EVs |
1033 | Vesiclepedia_690 | 28170197 | Homo sapiens | Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 | Bone marrow mesenchymal stem cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1034 | Vesiclepedia_2298 | 29339034 | Homo sapiens | Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer | Pancreatic duct fluid | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1035 | Vesiclepedia_1664 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Breast cancer cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1036 | Vesiclepedia_655 | 28290293 | Bos taurus | Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. | Bovine milk | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
1037 | Vesiclepedia_99 | 21828046 | Rattus norvegicus | The proteo-lipidic composition of exosomes changes during reticulocyte maturation. | Reticulocytes |
Protein Lipids |
Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1038 | Vesiclepedia_1835 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
1039 | Vesiclepedia_1540 | 33658392 | Homo sapiens | Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma | Lung cancer cells |
Protein miRNA |
Minute High-Efficiency Exosome Precipitation Reagent Filtration |
Exosomes | Small EVs |
1040 | Vesiclepedia_1700 | 34108659 | Equus caballus | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Serum | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1041 | Vesiclepedia_3396 | 31792209 | Homo sapiens | Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles | Fibroblasts | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1042 | Vesiclepedia_3081 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1043 | Vesiclepedia_2487 | 34388111 | Homo sapiens | miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis | Monocytic leukemia cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1044 | Vesiclepedia_564 | 26858453 | Homo sapiens | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes | Dendritic cells | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Exosomes | EVs |
1045 | Vesiclepedia_995 | 24434149 | Homo sapiens | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. | Ovarian cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1046 | Vesiclepedia_2231 | 36648227 | Mus musculus | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Macrophage | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1047 | Vesiclepedia_429 | 21595033 | Homo sapiens | Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. | Urine | Protein | - | Exosomes | EVs |
1048 | Vesiclepedia_1570 | 33738083 | Homo sapiens | Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases | Colorectal cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1049 | Vesiclepedia_1443 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1050 | Vesiclepedia_1235 | 25421927 | Heligmosomoides polygyrus | Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. | Heligmosomoides polygyrus |
miRNA Protein |
Filtration Ultracentrifugation |
Exosomes | EVs |
1051 | Vesiclepedia_1338 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | White adipose tissue | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1052 | Vesiclepedia_138 | 22723089 | Homo sapiens | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. | Prostate cancer cells | Protein | Sucrose density gradient | Exosomes | EVs |
1053 | Vesiclepedia_1460 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1054 | Vesiclepedia_88 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Stomach cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1055 | Vesiclepedia_2498 | 34329193 | Homo sapiens | CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis | Breast cancer cells |
Protein miRNA circRNA |
Total Exosome Isolation Reagent | Exosomes | EVs |
1056 | Vesiclepedia_737 | 25220352 | Mus musculus | Surface functionalization of exosomes using click chemistry. | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1057 | Vesiclepedia_2643 | 35649370 | Homo sapiens | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Mammary epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1058 | Vesiclepedia_475 | 23056502 | Homo sapiens | Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. | Melanoma cells | mRNA | - | Exosomes | EVs |
1059 | Vesiclepedia_2758 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
1060 | Vesiclepedia_3275 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1061 | Vesiclepedia_1364 | 32132711 | Homo sapiens | Decoy exosomes provide protection against bacterial toxins | Lung cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1062 | Vesiclepedia_3282 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
1063 | Vesiclepedia_965 | 25844599 | Homo sapiens | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. | Serum | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1064 | Vesiclepedia_469 | 23029346 | Echinostoma caproni | Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. | Echinostoma caproni | Protein | - | Exosomes/Extracellular vesicles/Microvesicles | EVs |
1065 | Vesiclepedia_271 | 10903724 | Homo sapiens | Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface | B cells | Protein | Differential centrifugation | Exosomes | EVs |
1066 | Vesiclepedia_54 | 14975938 | Homo sapiens | Proteomic analysis of exosomes isolated from human malignant pleural effusions. | Malignant pleural effusions | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
1067 | Vesiclepedia_2486 | 34388111 | Homo sapiens | miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis | Monocytic leukemia cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1068 | Vesiclepedia_1663 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Mammary cancer-associated fibroblasts |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1069 | Vesiclepedia_25 | 15111327 | Homo sapiens | Proteomic analysis of exosomes secreted by human mesothelioma cells. | Mesothelioma cells | Protein | Differential centrifugation | Exosomes | EVs |
1070 | Vesiclepedia_4 | 11487543 | Homo sapiens | Intestinal epithelial cells secrete exosome-like vesicles. | Epithelial cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
1071 | Vesiclepedia_2757 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
1072 | Vesiclepedia_2333 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1073 | Vesiclepedia_2646 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1074 | Vesiclepedia_1291 | 19912576 | Homo sapiens | HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. | Lymphoblasts | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1075 | Vesiclepedia_807 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1076 | Vesiclepedia_2917 | 26061593 | Homo sapiens | Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1077 | Vesiclepedia_699 | 28811610 | Homo sapiens | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1078 | Vesiclepedia_1831 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Lung cancer cells | miRNA | Centrifugation Filtration ExoQuick Kit |
Exosomes | Small EVs |
1079 | Vesiclepedia_1074 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
1080 | Vesiclepedia_721 | 26148937 | Homo sapiens | Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. | Cholangiocarcinoma cells | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
1081 | Vesiclepedia_1323 | 33431899 | Mus musculus | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Faeces |
Protein Lipid miRNA |
Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
1082 | Vesiclepedia_1070 | 29937354 | Homo sapiens | Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. | Glioblastoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1083 | Vesiclepedia_103 | 21763319 | Homo sapiens | Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. | Pancreatic cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration Ultracentrifugation |
Exosomes | EVs |
1084 | Vesiclepedia_2440 | 29335551 | Homo sapiens | Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer | Liver cancer cells |
Protein miRNA |
Filtration Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1085 | Vesiclepedia_1454 | 31949130 | Homo sapiens | circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma | Lung cancer cells | circRNA | Total Exosome Isolation Reagent | Exosomes | Small EVs |
1086 | Vesiclepedia_3284 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
1087 | Vesiclepedia_975 | 22808001 | Homo sapiens | Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. | Serum | Protein | Filtration ExoQuick |
Exosomes | EVs |
1088 | Vesiclepedia_3413 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | miRNA | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
1089 | Vesiclepedia_917 | 28687758 | Sus scrofa | Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers | Polarised retinal pigmented epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1090 | Vesiclepedia_1089 | 25065644 | Homo sapiens | Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. | Duodenal cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration |
Exosomes | EVs |
1091 | Vesiclepedia_2438 | 29335551 | Homo sapiens | Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer | Liver cancer cells |
Protein miRNA |
Filtration Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1092 | Vesiclepedia_29 | 19109410 | Homo sapiens | Proteomic and immunologic analyses of brain tumor exosomes. | Serum | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
1093 | Vesiclepedia_1499 | 33982667 | Homo sapiens | Exosomal circRNA 0001445 promotes glioma progression through miRNA-127-5p/SNX5 pathway | Glioblastoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1094 | Vesiclepedia_1200 | 27780738 | Homo sapiens | Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. | Cerebrospinal fluid | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1095 | Vesiclepedia_2606 | 36581340 | Homo sapiens | Rab27b, a Regulator of Exosome Secretion, Is Associated With Peritoneal Metastases in Gastric Cancer | Gastric cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1096 | Vesiclepedia_1185 | 28042326 | Homo sapiens | Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model. | Synovial mesenchymal stem cells | miRNA | Differential centrifugation Filtration Sucrose density gradient |
Exosomes | EVs |
1097 | Vesiclepedia_104 | 21763319 | Homo sapiens | Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. | Pancreatic cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration Ultracentrifugation |
Exosomes | EVs |
1098 | Vesiclepedia_327 | 20428099 | Homo sapiens | Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease | Urine | mRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1099 | Vesiclepedia_457 | 22723089 | Homo sapiens | Exosomes as Biomarker Enriched Microvesicles: Characterization of Exosomal Proteins derived from a Panel of Prostate Cell Lines with distinct AR phenotypes. | Prostate cancer cells | Lipids | - | Exosomes/Membrane vesicles/Microvesicles | EVs |
1100 | Vesiclepedia_78 | 20224111 | Homo sapiens | Proteomics analysis of bladder cancer exosomes. | Urine | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
1101 | Vesiclepedia_2632 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1102 | Vesiclepedia_554 | 24009898 | Mus musculus | Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. | Cardiomyocytes | mRNA | - | Exosomes/Extracellular vesicles | EVs |
1103 | Vesiclepedia_679 | 29951053 | Mus musculus | Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. | Myeloid-derived suppressor cells | Protein | Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1104 | Vesiclepedia_523 | 23658846 | Mus musculus | Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. | Macrophage | Protein | - | Exosomes | EVs |
1105 | Vesiclepedia_111 | 21601258 | Homo sapiens | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. | Serum |
Protein miRNA |
Differential centrifugation Sucrose density gradient Immunobeads (CD24) |
Exosomes | EVs |
1106 | Vesiclepedia_3015 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1107 | Vesiclepedia_777 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1108 | Vesiclepedia_652 | 28290293 | Homo sapiens | Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. | Breast milk | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
1109 | Vesiclepedia_185 | 22116803 | Equus caballus | Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle | Follicular fluid |
Protein miRNA |
Differential centrifugation ExoQuick |
Exosomes | EVs |
1110 | Vesiclepedia_969 | 25844599 | Homo sapiens | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. | Serum | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1111 | Vesiclepedia_723 | 25802036 | Homo sapiens | Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. | Glioblastoma cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1112 | Vesiclepedia_981 | 25458527 | Homo sapiens | Benchtop isolation and characterization of functional exosomes by sequential filtration | Breast cancer cells | Protein | Sequential filtration | Exosomes | EVs |
1113 | Vesiclepedia_805 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1114 | Vesiclepedia_1242 | 25261722 | Homo sapiens | Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. | Glioblastoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1115 | Vesiclepedia_758 | 28357077 | Mus musculus | Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells | Osteocytes | miRNA | Total Exosome Isolation Kit Differential centrifugation |
Exosomes | EVs |
1116 | Vesiclepedia_555 | 24046871 | Homo sapiens | Molecular lipidomics of exosomes released by PC-3 prostate cancer cells. | Prostate cancer cells | Lipids | - | Exosomes/Microvesicles | EVs |
1117 | Vesiclepedia_1084 | 25104112 | Homo sapiens | Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. | Plasma | Protein | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Exosomes | EVs |
1118 | Vesiclepedia_2523 | 34315885 | Homo sapiens | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease | Urine | Protein | Centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1119 | Vesiclepedia_1826 | 36494333 | Homo sapiens | Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis | Serum | miRNA | Total Exosome Isolation Kit | Exosomes | Small EVs |
1120 | Vesiclepedia_722 | 25802036 | Homo sapiens | Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. | Glioblastoma cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1121 | Vesiclepedia_726 | 25471207 | Homo sapiens | Intraluminal proteome and peptidome of human urinary extracellular vesicles. | Urine | Protein | Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration |
Exosomes | EVs |
1122 | Vesiclepedia_901 | 26100252 | Homo sapiens | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts | Chronic lymphocytic leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1123 | Vesiclepedia_528 | 23767874 | Homo sapiens | Biochemical and biological characterization of exosomes containing prominin-1/CD133. | Melanoma cells | Lipids | - | Exosomes/Microvesicles | EVs |
1124 | Vesiclepedia_1805 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Serum |
Protein miRNA |
ExoQuick Kit | Exosomes | Small EVs |
1125 | Vesiclepedia_3059 | 33827783 | Mus musculus | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1126 | Vesiclepedia_2672 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1127 | Vesiclepedia_141 | 22723089 | Homo sapiens | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. | Prostate cancer cells | Protein | Sucrose density gradient | Exosomes | EVs |
1128 | Vesiclepedia_3010 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1129 | Vesiclepedia_2276 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma |
Protein miRNA |
Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
1130 | Vesiclepedia_565 | 26858453 | Homo sapiens | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes | Dendritic cells | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Exosomes | EVs |
1131 | Vesiclepedia_445 | 22418980 | Homo sapiens | A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. | Urine | Protein | - | Exosomes | EVs |
1132 | Vesiclepedia_85 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Lung cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1133 | Vesiclepedia_833 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
1134 | Vesiclepedia_688 | 28170197 | Homo sapiens | Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 | Endometrium-derived mesenchymal stem cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1135 | Vesiclepedia_81 | 20458337 | Homo sapiens | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 | B cells | Protein | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Exosomes | EVs |
1136 | Vesiclepedia_2327 | 31807237 | Homo sapiens | Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1137 | Vesiclepedia_2444 | 34489604 | Mus musculus | Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 | Hepatocytes |
Protein miRNA |
Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1138 | Vesiclepedia_3141 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Lung cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1139 | Vesiclepedia_2675 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1140 | Vesiclepedia_2028 | 36455873 | Homo sapiens | Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF | Plasma |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1141 | Vesiclepedia_1691 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Pancreatic cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1142 | Vesiclepedia_2252 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1143 | Vesiclepedia_503 | 23459212 | Bos taurus | Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis. | Bovine milk | Protein | - | Exosomes | EVs |
1144 | Vesiclepedia_1654 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Glioblastoma cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1145 | Vesiclepedia_3021 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1146 | Vesiclepedia_546 | 23983189 | Homo sapiens | Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. | B cells | Protein | - | Exosomes/Extracellular vesicles/Microvesicles | EVs |
1147 | Vesiclepedia_2238 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1148 | Vesiclepedia_1665 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Normal mammary epithelial cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1149 | Vesiclepedia_1135 | 23861904 | Homo sapiens | Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. | Placental mesenchymal stem cells | Protein | Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation |
Exosomes | EVs |
1150 | Vesiclepedia_3128 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Hippocampal neuronal cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1151 | Vesiclepedia_1263 | 24371517 | Homo sapiens | Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. | Urine | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1152 | Vesiclepedia_1442 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1153 | Vesiclepedia_3055 | 33827783 | Mus musculus | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic duct epithelial cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1154 | Vesiclepedia_2338 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Plasma | miRNA | ExoQuick Kit Centrifugation |
Exosomes | Small EVs |
1155 | Vesiclepedia_1091 | 25065644 | Homo sapiens | Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. | Duodenal cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration |
Exosomes | EVs |
1156 | Vesiclepedia_2673 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1157 | Vesiclepedia_928 | 25483805 | Gallus gallus | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties | Notochord cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1158 | Vesiclepedia_1819 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1159 | Vesiclepedia_354 | 24115447 | Homo sapiens | Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma | Plasma | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1160 | Vesiclepedia_1701 | 34108659 | Capra hircus | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Serum | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1161 | Vesiclepedia_1448 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Plasma | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1162 | Vesiclepedia_958 | 26196085 | Homo sapiens | Identification of prostate cancer biomarkers in urinary exosomes. | Urine | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
1163 | Vesiclepedia_34 | 19190083 | Homo sapiens | Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. | Tracheobronchial cells |
Protein mRNA |
Differential centrifugation Filtration Sucrose density gradient |
Exosomes | EVs |
1164 | Vesiclepedia_673 | 29953960 | Homo sapiens | Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. | Macrophage | Protein | Microfiltration Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1165 | Vesiclepedia_2998 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1166 | Vesiclepedia_440 | 22251860 | Homo sapiens | RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls. | Serum | mRNA | - | Exosomes/Microvesicles | EVs |
1167 | Vesiclepedia_767 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1168 | Vesiclepedia_3018 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1169 | Vesiclepedia_30 | 16446100 | Rattus norvegicus | Exosomes are released by cultured cortical neurones. | Cortical neurons | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
1170 | Vesiclepedia_1286 | 20880880 | Homo sapiens | Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis. | Bronchoalveolar lavage fluid | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1171 | Vesiclepedia_3369 | 34887515 | Homo sapiens | Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets | Colon cancer cells | Protein | Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation |
Exosomes | Small EVs |
1172 | Vesiclepedia_2501 | 34329193 | Homo sapiens | CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis | Breast cancer cells | miRNA | Total Exosome Isolation Reagent | Exosomes | EVs |
1173 | Vesiclepedia_1331 | 33431899 | Mus musculus | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Colorectal cancer cells | Protein | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
1174 | Vesiclepedia_2326 | 31807237 | Homo sapiens | Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1175 | Vesiclepedia_2345 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1176 | Vesiclepedia_1282 | 22345510 | Rattus norvegicus | Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. | Insulinoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1177 | Vesiclepedia_825 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
1178 | Vesiclepedia_1115 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1179 | Vesiclepedia_3536 | 31608233 | Homo sapiens | Double-Stranded DNA in Exosomes of Malignant Pleural Effusions as a Novel DNA Source for EGFR Mutation Detection in Lung Adenocarcinoma | Pleural effusion | dsDNA | ExoQuick Kit | Exosomes | Small EVs |
1180 | Vesiclepedia_3033 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1181 | Vesiclepedia_2659 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1182 | Vesiclepedia_432 | 21751344 | Pseudomonas aeruginosa | Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa. | Pseudomonas aeruginosa | Protein | - | Exosomes/Membrane vesicles | EVs |
1183 | Vesiclepedia_912 | 28687758 | Sus scrofa | Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers | Polarised retinal pigmented epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1184 | Vesiclepedia_389 | 18819103 | Homo sapiens | Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen. | Seminal fluid | Protein | - | Exosomes/Prostasomes | EVs |
1185 | Vesiclepedia_87 | 20949044 | Homo sapiens | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1186 | Vesiclepedia_739 | 25157233 | Homo sapiens | Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. | Placenta | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1187 | Vesiclepedia_759 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1188 | Vesiclepedia_2354 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Stromal vascular fraction | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1189 | Vesiclepedia_2633 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1190 | Vesiclepedia_810 | 29932869 | Mus musculus | Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy | Schwann cells | miRNA | Filtration Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1191 | Vesiclepedia_1156 | 21212511 | Homo sapiens | Proteomic analysis of two types of exosomes in human whole saliva. | Saliva | Protein | Differential centrifugation Filtration Ultracentrifugation Gel filtration |
Exosomes | EVs |
1192 | Vesiclepedia_1456 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1193 | Vesiclepedia_2968 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1194 | Vesiclepedia_1357 | 32438511 | Homo sapiens | Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion | Colorectal cancer cells | Protein | Differential centrifugation Filtration OptiPrep density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1195 | Vesiclepedia_1531 | 33752173 | Homo sapiens | Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression | Plasma | miRNA | Total Exosome Isolation Kit Centrifugation |
Exosomes | Small EVs |
1196 | Vesiclepedia_1088 | 25065644 | Homo sapiens | Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. | Duodenal cancer cells | Protein | Differential centrifugation Filtration Ultrafiltration |
Exosomes | EVs |
1197 | Vesiclepedia_49 | 14582906 | Homo sapiens | Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. | Bronchoalveolar lavage fluid | Protein | Differential centrifugation Immunobeads (EpCAM) |
Exosomes | EVs |
1198 | Vesiclepedia_1807 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells |
Protein miRNA |
Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1199 | Vesiclepedia_348 | 22285593 | Homo sapiens | Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. | Colorectal cancer cells | Protein | Differential centrifugation Filtration Immunoaffinity (EpCAM) Ultracentrifugation |
Exosomes | EVs |
1200 | Vesiclepedia_782 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1201 | Vesiclepedia_76 | 20224111 | Homo sapiens | Proteomics analysis of bladder cancer exosomes. | Bladder cancer cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
1202 | Vesiclepedia_2361 | 36717543 | Rattus norvegicus | Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury | Schwann cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1203 | Vesiclepedia_1457 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1204 | Vesiclepedia_968 | 25844599 | Homo sapiens | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. | Serum | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1205 | Vesiclepedia_1095 | 24976626 | Homo sapiens | Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells. | Renal proximal tubule cells | Protein | Differential centrifugation Ultracentrifugation Immunoaffinity |
Exosomes | EVs |
1206 | Vesiclepedia_2349 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1207 | Vesiclepedia_3020 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1208 | Vesiclepedia_1260 | 24371517 | Homo sapiens | Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. | Prostate cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1209 | Vesiclepedia_2282 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
1210 | Vesiclepedia_779 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1211 | Vesiclepedia_2671 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1212 | Vesiclepedia_2692 | 35210436 | Homo sapiens | M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway | Macrophage |
Protein mRNA |
Total Exosome Isolation Reagent | Exosomes | Small EVs |
1213 | Vesiclepedia_880 | 29955024 | Homo sapiens | Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells | Myeloid leukemia cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1214 | Vesiclepedia_1329 | 33431899 | Mus musculus | High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance | Faeces | Lipid | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
1215 | Vesiclepedia_974 | 22808001 | Homo sapiens | Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. | Serum | Protein | Filtration ExoQuick |
Exosomes | EVs |
1216 | Vesiclepedia_670 | 29953960 | Homo sapiens | Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. | Macrophage | Protein | Microfiltration Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1217 | Vesiclepedia_1343 | 33159193 | Rattus norvegicus | Treatment of infarcted heart tissue via the capture and local delivery of circulating exosomes through antibody-conjugated magnetic nanoparticles | Serum | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1218 | Vesiclepedia_2256 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1219 | Vesiclepedia_1199 | 27883272 | Homo sapiens | Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. | Serum |
miRNA Metabolites |
ExoQuick | Exosomes | EVs |
1220 | Vesiclepedia_2348 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1221 | Vesiclepedia_1655 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Glioblastoma cells |
Protein mRNA |
Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1222 | Vesiclepedia_3582 | 31555514 | Homo sapiens | Liquid biopsies using pleural effusion-derived exosomal DNA in advanced lung adenocarcinoma. | Pleural effusion | dsDNA-mutated | Ultracentrifugation | Exosomes | Small EVs |
1223 | Vesiclepedia_2617 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1224 | Vesiclepedia_3270 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1225 | Vesiclepedia_1837 | 36408942 | Homo sapiens | Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells | Mesenchymal stem cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1226 | Vesiclepedia_2334 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1227 | Vesiclepedia_1440 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells |
Protein miRNA |
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1228 | Vesiclepedia_1252 | 24939845 | Homo sapiens | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1229 | Vesiclepedia_793 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1230 | Vesiclepedia_3272 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
1231 | Vesiclepedia_1458 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Mammary epithelial cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1232 | Vesiclepedia_2624 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1233 | Vesiclepedia_886 | 25102470 | Homo sapiens | Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1234 | Vesiclepedia_3053 | 34294888 | Homo sapiens | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | Plasma | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1235 | Vesiclepedia_2475 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Breast cancer cells | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1236 | Vesiclepedia_3407 | 31666321 | Drosophila melanogaster | Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia | Hemolymph | Protein | Differential centrifugation ExoQuick Kit |
Exosomes | Small EVs |
1237 | Vesiclepedia_3078 | 33827783 | Homo sapiens | Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1238 | Vesiclepedia_2986 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1239 | Vesiclepedia_2001 | 34112803 | Homo sapiens | Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution | Plasma | Protein | Size exclusion chromatography Centrifugal ultrafiltration |
Exosomes | Small EVs |
1240 | Vesiclepedia_1127 | 24295599 | Mus musculus | Exosomes from myeloid-derived suppressor cells carry biologically active proteins. | Myeloid-derived suppressor cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1241 | Vesiclepedia_1142 | 23454749 | Homo sapiens | BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. | Bone marrow mesenchymal stromal cells | Protein | Differential centrifugation Ultracentrifugation Filtration ExoQuick |
Exosomes | EVs |
1242 | Vesiclepedia_1359 | 32132711 | Homo sapiens | Decoy exosomes provide protection against bacterial toxins | Lung cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1243 | Vesiclepedia_1340 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | Liver | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1244 | Vesiclepedia_3274 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
1245 | Vesiclepedia_3032 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1246 | Vesiclepedia_2912 | 26061593 | Homo sapiens | Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1247 | Vesiclepedia_837 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
1248 | Vesiclepedia_137 | 22723089 | Homo sapiens | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. | Prostate cancer cells | Protein | Sucrose density gradient | Exosomes | EVs |
1249 | Vesiclepedia_2245 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1250 | Vesiclepedia_3139 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Plasma |
Protein miRNA |
ExoQuick Kit | Exosomes | EVs |
1251 | Vesiclepedia_1202 | 27780738 | Homo sapiens | Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. | Cerebrospinal fluid | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1252 | Vesiclepedia_785 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Epithelial cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1253 | Vesiclepedia_1117 | 24391718 | Homo sapiens | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. | Prostate epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1254 | Vesiclepedia_1822 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1255 | Vesiclepedia_2616 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1256 | Vesiclepedia_1446 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1257 | Vesiclepedia_1047 | 28725021 | Bos taurus | Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. | Bovine milk | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1258 | Vesiclepedia_2299 | 29339034 | Homo sapiens | Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer | Pancreatic duct fluid | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1259 | Vesiclepedia_3142 | 34497265 | Homo sapiens | Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer | Lung epithelial cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1260 | Vesiclepedia_1550 | 33638284 | Canis lupus familiaris | Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition | Kidney cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1261 | Vesiclepedia_660 | 29964051 | Homo sapiens | Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway | Adipose tissue-derived stem cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1262 | Vesiclepedia_2340 | 36640325 | Mus musculus | Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis | Adipocytes | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1263 | Vesiclepedia_1453 | 31949130 | Homo sapiens | circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma | Lung cancer cells | circRNA | Total Exosome Isolation Reagent | Exosomes | Small EVs |
1264 | Vesiclepedia_977 | 22808001 | Homo sapiens | Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. | Serum | Protein | Filtration ExoQuick |
Exosomes | EVs |
1265 | Vesiclepedia_2466 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1266 | Vesiclepedia_2622 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1267 | Vesiclepedia_1673 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1268 | Vesiclepedia_1268 | 24218614 | Homo sapiens | Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. | Pancreatic cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1269 | Vesiclepedia_2765 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Tangential flow filtration | Exosomes | Small EVs |
1270 | Vesiclepedia_3279 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
1271 | Vesiclepedia_1215 | 27872147 | Rattus norvegicus | Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. | Islets | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1272 | Vesiclepedia_1143 | 23454749 | Homo sapiens | BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. | Bone marrow mesenchymal stromal cells | Protein | Differential centrifugation Ultracentrifugation Filtration ExoQuick |
Exosomes | EVs |
1273 | Vesiclepedia_3114 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Podocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1274 | Vesiclepedia_28 | 19109410 | Homo sapiens | Proteomic and immunologic analyses of brain tumor exosomes. | Glioma cells | Protein | Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
1275 | Vesiclepedia_2003 | 34112803 | Mus musculus | Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Centrifugal ultrafiltration |
Exosomes | Small EVs |
1276 | Vesiclepedia_21 | 19837982 | Homo sapiens | Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215. | Colorectal cancer cells | Protein | Filtration Ultracentrifugation Sucrose density gradient |
Exosomes | EVs |
1277 | Vesiclepedia_1132 | 23861904 | Homo sapiens | Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. | Placental mesenchymal stem cells | Protein | Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation |
Exosomes | EVs |
1278 | Vesiclepedia_1682 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1279 | Vesiclepedia_1541 | 33658392 | Homo sapiens | Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma | Lung cancer cells |
Protein miRNA |
Minute High-Efficiency Exosome Precipitation Reagent Filtration |
Exosomes | Small EVs |
1280 | Vesiclepedia_3280 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Total Exosome Isolation Reagent |
Exosomes | EVs |
1281 | Vesiclepedia_2243 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1282 | Vesiclepedia_698 | 28811610 | Homo sapiens | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1283 | Vesiclepedia_1054 | 29115712 | Mus musculus | Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. | Breast cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1284 | Vesiclepedia_1243 | 25261722 | Homo sapiens | Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. | Glioblastoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1285 | Vesiclepedia_1459 | 31969559 | Homo sapiens | Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer | Breast cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1286 | Vesiclepedia_1913 | 36270983 | Mus musculus | NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancer | Lung epithelial cells | Protein | Centrifugation Exosome Isolation Reagent |
Exosomes | Small EVs |
1287 | Vesiclepedia_3138 | 34500436 | Homo sapiens | MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells | Lung cancer cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1288 | Vesiclepedia_1677 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1289 | Vesiclepedia_2762 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
1290 | Vesiclepedia_1277 | 23344851 | Rattus norvegicus | Urinary exosomes and diabetic nephropathy: a proteomic approach. | Urine | Protein | Ultracentrifugation | Exosomes | EVs |
1291 | Vesiclepedia_2913 | 26061593 | Homo sapiens | Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue | Plasma | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1292 | Vesiclepedia_3149 | 29438363 | Homo sapiens | CD9-positive exosomes from cancer-associated fibroblasts stimulate the migration ability of scirrhous-type gastric cancer cells | Fibroblasts | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1293 | Vesiclepedia_1257 | 24400796 | Homo sapiens | Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. | Retinal pigment epithelial cells | Protein | ExoQuick | Exosomes | EVs |
1294 | Vesiclepedia_2239 | 36648227 | Escherichia coli | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Escherichia coli | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1295 | Vesiclepedia_1071 | 29937354 | Homo sapiens | Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. | Glioblastoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1296 | Vesiclepedia_1817 | 36517516 | Homo sapiens | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes | Breast cancer cells | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1297 | Vesiclepedia_2775 | 33432243 | Homo sapiens | Exosome detection via the ultrafast-isolation system: EXODUS | Urine | Protein | Filtration Exosome detection via ultrafast-isolation system (EXODUS) |
Exosomes | Small EVs |
1298 | Vesiclepedia_2656 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1299 | Vesiclepedia_1098 | 24513287 | Mus musculus | Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. | adipocytes | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
1300 | Vesiclepedia_1685 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Breast cancer cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1301 | Vesiclepedia_1445 | 29472616 | Homo sapiens | Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 | Colorectal cancer cells | miRNA | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1302 | Vesiclepedia_2281 | 29295981 | Homo sapiens | Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis | Plasma | miRNA | Differential centrifugation Polyethylene glycol-based precipitation Centrifugation |
Exosomes | Small EVs |
1303 | Vesiclepedia_1337 | 33199621 | Mus musculus | Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice | White adipose tissue | miRNA | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1304 | Vesiclepedia_663 | 29956871 | Homo sapiens | Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis | Bronchoalveolar lavage fluid | Protein | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
1305 | Vesiclepedia_914 | 28687758 | Sus scrofa | Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers | Polarised retinal pigmented epithelial cells | Protein | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1306 | Vesiclepedia_1839 | 36408942 | Rattus norvegicus | Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells | Bone marrow mesenchymal stem cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1307 | Vesiclepedia_1147 | 23173708 | Rattus norvegicus | Wnt3a induces exosome secretion from primary cultured rat microglia. | Primary microglial cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1308 | Vesiclepedia_3001 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1309 | Vesiclepedia_1245 | 25167841 | Homo sapiens | Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. | Serum | Protein | CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips | Exosomes | EVs |
1310 | Vesiclepedia_391 | 19327352 | Bos taurus | Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes. | Serum | Protein | - | Exosomes | EVs |
1311 | Vesiclepedia_1158 | 20662102 | Mus musculus | Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages. | Macrophage | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1312 | Vesiclepedia_820 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
1313 | Vesiclepedia_814 | 23376832 | Rattus norvegicus | Cardiac myocyte exosomes: stability, HSP60, and proteomics | Cardiomyocytes | Protein | Differential centrifugation Filtration ExoQuick Ultracentrifugation |
Exosomes | EVs |
1314 | Vesiclepedia_2464 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1315 | Vesiclepedia_736 | 25285581 | Mus musculus | Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells. | Myeloid-derived suppressor cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | EVs |
1316 | Vesiclepedia_2465 | 34465793 | Homo sapiens | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer | Serum | miRNA | Centrifugation Filtration Ultracentrifugation |
Exosomes | Small EVs |
1317 | Vesiclepedia_707 | 28811610 | Homo sapiens | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Exosomes | EVs |
1318 | Vesiclepedia_110 | 21601258 | Homo sapiens | Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. | Ascites |
Protein miRNA |
Differential centrifugation Sucrose density gradient |
Exosomes | EVs |
1319 | Vesiclepedia_2696 | 35210436 | Homo sapiens | M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway | Macrophage | mRNA | Total Exosome Isolation Reagent | Exosomes | Small EVs |
1320 | Vesiclepedia_1027 | 24211404 | Homo sapiens | Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis. | Urine | Protein | Ultracentrifugation ExoQuick |
Exosomes | EVs |
1321 | Vesiclepedia_794 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1322 | Vesiclepedia_485 | 23214914 | Trypanosoma cruzi | Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. | Metacyclic trypomastigotes | Protein | - | Exosomes/Extracellular vesicles/Ectosomes | EVs |
1323 | Vesiclepedia_665 | 29956871 | Homo sapiens | Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis | Bronchoalveolar lavage fluid | miRNA | Differential centrifugation Ultracentrifugation Filtration |
Exosomes | EVs |
1324 | Vesiclepedia_768 | 29953723 | Salmo salar | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | Leukocytes | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1325 | Vesiclepedia_3121 | 30967557 | Mus musculus | KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a | Kidney cells | Protein | Differential centrifugation Filtration Sucrose density gradient centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1326 | Vesiclepedia_2674 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1327 | Vesiclepedia_2230 | 36648227 | Mus musculus | Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes | Macrophage | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1328 | Vesiclepedia_2984 | 30089911 | Homo sapiens | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1329 | Vesiclepedia_1672 | 34108659 | Homo sapiens | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker | Embryonic kidney cells | Protein | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Exosomes | Small EVs |
1330 | Vesiclepedia_804 | 29953723 | Homo sapiens | Stimulation of exosome release by extracellular DNA is conserved across multiple cell types | T cells | Protein | Differential centrifugation Filtration Ultracentrifugation |
Exosomes | EVs |
1331 | Vesiclepedia_3278 | 34593794 | Mus musculus | A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis | Melanoma cells | Protein | Differential centrifugation Ultracentrifugation |
Exosomes | Small EVs |
1332 | Vesiclepedia_2652 | 35649370 | Canis lupus familiaris | Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells | Kidney epithelial cells | Protein | Differential centrifugation Filtration Immunoaffinity capture Ultracentrifugation |
Exosomes | Small EVs |
1333 | Vesiclepedia_1543 | 33767144 | Homo sapiens | Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells | Cervical cancer cells | Protein | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Exosomes | Small EVs |
1334 | Vesiclepedia_335 | 20976003 | Homo sapiens | Selective release of microRNA species from normal and malignant mammary epithelial cells | Breast cancer cells |
Protein miRNA |
Differential centrifugation Filtration |
Exosomes | EVs |