Browse results for vesicle type: Exosomes


 Vesiclepedia IDPubMed IDSpeciesExperiment descriptionSampleIdentificationsIsolation methodsVesicle typeMISEV
1 Vesiclepedia_2745 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
2 Vesiclepedia_510 23521563 Homo sapiens First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Ewing's sarcoma cells mRNA - Exosomes/Extracellular vesicles EVs
3 Vesiclepedia_11 12519789 Homo sapiens Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation. B cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes EVs
4 Vesiclepedia_791 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
5 Vesiclepedia_2640 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Cervical cancer cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
6 Vesiclepedia_93 20124479 Rattus norvegicus Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Pancreatic cancer cells Protein
mRNA
Differential centrifugation
Sucrose density gradient
Exosomes EVs
7 Vesiclepedia_6 11306949 Mus musculus Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes. Mast cells Protein - Exosomes EVs
8 Vesiclepedia_1356 32438511 Homo sapiens Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion Colorectal cancer cells Protein Differential centrifugation
Filtration
OptiPrep density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
9 Vesiclepedia_1217 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
10 Vesiclepedia_923 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
11 Vesiclepedia_1330 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces Lipid Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
12 Vesiclepedia_2972 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
13 Vesiclepedia_693 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Bone marrow mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
14 Vesiclepedia_795 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
15 Vesiclepedia_3073 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
16 Vesiclepedia_1935 36103526 Homo sapiens Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases Hepatic stellate cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
17 Vesiclepedia_3160 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
18 Vesiclepedia_216 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Breast cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
19 Vesiclepedia_3410 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph miRNA Differential centrifugation
ExoQuick Kit
Exosomes Small EVs
20 Vesiclepedia_84 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Lung cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
21 Vesiclepedia_2257 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
22 Vesiclepedia_813 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
23 Vesiclepedia_2318 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Plasma Protein
small RNA
ExoQuick Kit Extracellular vesicles/Exosomes EVs
24 Vesiclepedia_2347 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
25 Vesiclepedia_125 21059916 Homo sapiens Human tumor virus utilizes exosomes for intercellular communication. Nasopharyngeal carcinoma cells Protein Differential centrifugation Exosomes EVs
26 Vesiclepedia_31 10572093 Homo sapiens Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. Platelets Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
27 Vesiclepedia_1086 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes EVs
28 Vesiclepedia_765 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
29 Vesiclepedia_1105 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
30 Vesiclepedia_1569 33738083 Homo sapiens Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
31 Vesiclepedia_399 19530224 Homo sapiens Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. Keratinocytes Protein - Exosomes EVs
32 Vesiclepedia_1546 33767144 Homo sapiens Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells Cervical cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
33 Vesiclepedia_2456 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
34 Vesiclepedia_508 23511837 Homo sapiens Differential protein profiling of renal cell carcinoma urinary exosomes. Urine Protein - Exosomes/Nanovesicles EVs
35 Vesiclepedia_1113 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
36 Vesiclepedia_1250 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
37 Vesiclepedia_3079 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
38 Vesiclepedia_3050 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Monocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
39 Vesiclepedia_1342 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice Muscle miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
40 Vesiclepedia_1159 20409149 Homo sapiens Transdifferentiated circulating monocytes release exosomes containing 14-3-3 proteins with matrix metalloproteinase-1 stimulating effect for dermal fibroblasts. Keratinocytes Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
41 Vesiclepedia_2651 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
42 Vesiclepedia_1154 22057275 Homo sapiens Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. Cerebrospinal fluid Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
43 Vesiclepedia_1069 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
44 Vesiclepedia_678 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Myeloid-derived suppressor cells Protein Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
45 Vesiclepedia_1366 32132711 Mus musculus Decoy exosomes provide protection against bacterial toxins Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
46 Vesiclepedia_139 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes EVs
47 Vesiclepedia_1111 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
48 Vesiclepedia_2978 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Iodixanol density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
49 Vesiclepedia_1661 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic duct epithelial cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
50 Vesiclepedia_1436 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
51 Vesiclepedia_1101 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. Serum Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
52 Vesiclepedia_32 18452139 Homo sapiens Primary human keratinocytes externalize stratifin protein via exosomes. Keratinocytes Protein Differential centrifugation
Sucrose density gradient
Diafiltration
Exosomes EVs
53 Vesiclepedia_3051 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Plasma miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
54 Vesiclepedia_2471 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
55 Vesiclepedia_778 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
56 Vesiclepedia_1100 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. adipocytes Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
57 Vesiclepedia_83 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Lung cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
58 Vesiclepedia_770 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
59 Vesiclepedia_3045 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Plasma Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes EVs
60 Vesiclepedia_450 22451062 Homo sapiens A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: application to RCC urinary exosomes. Urine Lipids - Exosomes EVs
61 Vesiclepedia_119 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
62 Vesiclepedia_2751 35173168 Homo sapiens Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
63 Vesiclepedia_2966 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
64 Vesiclepedia_918 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
65 Vesiclepedia_2776 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
66 Vesiclepedia_484 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Epimastigotes Protein - Exosomes/Extracellular vesicles/Ectosomes EVs
67 Vesiclepedia_1248 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
68 Vesiclepedia_802 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
69 Vesiclepedia_3062 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
70 Vesiclepedia_1688 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
71 Vesiclepedia_899 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
72 Vesiclepedia_2621 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
73 Vesiclepedia_2461 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
74 Vesiclepedia_471 23035643 Drosophila melanogaster Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes. Drosophila S2 cells Protein - Exosomes EVs
75 Vesiclepedia_2344 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
76 Vesiclepedia_786 29953723 Oncorhynchus tshawytscha Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
77 Vesiclepedia_1696 34108659 Mus musculus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic fibroblasts Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
78 Vesiclepedia_1087 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes EVs
79 Vesiclepedia_1997 34112803 Mus musculus Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Exosomes Small EVs
80 Vesiclepedia_3052 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Plasma miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
81 Vesiclepedia_2693 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage Protein
mRNA
Total Exosome Isolation Reagent Exosomes Small EVs
82 Vesiclepedia_130 18309083 Mus musculus Ceramide triggers budding of exosome vesicles into multivesicular endosomes Oligodendrocytes Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes EVs
83 Vesiclepedia_3116 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Brain Protein Differential centrifugation
Filtration
Sucrose density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
84 Vesiclepedia_461 22848702 Homo sapiens Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles. Medulloblastoma cells Protein - Exosomes/Membrane vesicles/Extracellular vesicles EVs
85 Vesiclepedia_924 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
86 Vesiclepedia_57 17700640 Homo sapiens CD24 is a marker of exosomes secreted into urine and amniotic fluid. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
87 Vesiclepedia_2983 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
88 Vesiclepedia_970 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
89 Vesiclepedia_1334 33368224 Homo sapiens Colorectal cancer prompted adipose tissue browning and cancer cachexia through transferring exosomal miR-146b-5p Colorectal cancer cells Protein
mRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
90 Vesiclepedia_720 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocytes Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
91 Vesiclepedia_1201 27780738 Homo sapiens Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Cerebrospinal fluid miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
92 Vesiclepedia_1237 25421927 Heligmosomoides polygyrus Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Heligmosomoides polygyrus miRNA
Protein
Filtration
Ultracentrifugation
Exosomes EVs
93 Vesiclepedia_925 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
94 Vesiclepedia_39 15210972 Mus musculus Cells release prions in association with exosomes. Mov neuroglial cell Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
95 Vesiclepedia_669 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophage Protein Microfiltration
Differential centrifugation
Ultracentrifugation
Exosomes EVs
96 Vesiclepedia_3083 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic duct epithelial cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
97 Vesiclepedia_1692 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
98 Vesiclepedia_719 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
99 Vesiclepedia_3118 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Brain Protein Differential centrifugation
Filtration
Sucrose density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
100 Vesiclepedia_823 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
101 Vesiclepedia_47 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. B cells Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes EVs
102 Vesiclepedia_3251 34545097 Homo sapiens Exosome-mediated stable epigenetic repression of HIV-1 Embryonic kidney cells Protein
mRNA
Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
103 Vesiclepedia_1099 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. adipocytes Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
104 Vesiclepedia_3074 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
105 Vesiclepedia_3061 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
106 Vesiclepedia_2336 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
107 Vesiclepedia_1567 33523942 Homo sapiens Exosomal delivery of NF-κB inhibitor delays LPS-induced preterm birth and modulates fetal immune cell profile in mouse models Embryonic kidney cells Protein Centrifugation
Filtration
Size exclusion chromatography
Exosomes Small EVs
108 Vesiclepedia_1221 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Insulinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
109 Vesiclepedia_3400 31054213 Homo sapiens Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma Cholangiocarcinoma cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
110 Vesiclepedia_486 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles EVs
111 Vesiclepedia_509 23521563 Homo sapiens First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Ewing's sarcoma cells mRNA - Exosomes/Extracellular vesicles EVs
112 Vesiclepedia_1534 33589572 Homo sapiens Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis Plasma Protein
lncRNA
Centrifugation
ExoQuick Kit
Exosomes Small EVs
113 Vesiclepedia_552 24009898 Mus musculus Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. Cardiomyocytes mRNA - Exosomes/Extracellular vesicles EVs
114 Vesiclepedia_2423 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
115 Vesiclepedia_1529 33752173 Homo sapiens Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression Breast cancer cells miRNA Total Exosome Isolation Kit
Centrifugation
Exosomes Small EVs
116 Vesiclepedia_2419 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
117 Vesiclepedia_127 21828046 Rattus norvegicus Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
118 Vesiclepedia_740 25157233 Homo sapiens Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Placenta choriocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
119 Vesiclepedia_1267 24218614 Homo sapiens Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
120 Vesiclepedia_413 20535238 Rattus norvegicus Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. Urine Protein - Exosomes EVs
121 Vesiclepedia_511 23521563 Homo sapiens First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Ewing's sarcoma cells mRNA - Exosomes/Extracellular vesicles EVs
122 Vesiclepedia_2447 34489604 Mus musculus Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 Hepatocytes miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
123 Vesiclepedia_525 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophage Protein - Exosomes EVs
124 Vesiclepedia_3046 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Plasma Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes EVs
125 Vesiclepedia_829 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
126 Vesiclepedia_431 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine Protein - Exosomes EVs
127 Vesiclepedia_884 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
128 Vesiclepedia_536 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells Protein - Exosomes/Microvesicles/Oncosomes/Microparticles EVs
129 Vesiclepedia_65 19415654 Homo sapiens Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7. Breast cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
130 Vesiclepedia_1657 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Foreskin fibroblasts Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
131 Vesiclepedia_2999 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
132 Vesiclepedia_237 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Melanoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
133 Vesiclepedia_3133 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
134 Vesiclepedia_1053 29115712 Mus musculus Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
135 Vesiclepedia_1161 22641613 Homo sapiens Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
136 Vesiclepedia_973 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes EVs
137 Vesiclepedia_1922 36253358 Mus musculus Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM Mesenchymal stem cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
138 Vesiclepedia_1085 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
139 Vesiclepedia_3567 28750687 Homo sapiens Extracellular vesicles from human liver stem cells restore argininosuccinate synthase deficiency Liver stem cells dsDNA Differential centrifugation
Ultracentrifugation
Extracellular vesicles|Exosomes EVs
140 Vesiclepedia_672 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophage Protein Microfiltration
Differential centrifugation
Ultracentrifugation
Exosomes EVs
141 Vesiclepedia_1537 33523480 Homo sapiens Human fibroblast-derived extracellular vesicles promote hair growth in cultured human hair follicles Fibroblasts Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
142 Vesiclepedia_2747 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
143 Vesiclepedia_713 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
144 Vesiclepedia_798 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
145 Vesiclepedia_3273 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
146 Vesiclepedia_277 22030351 Homo sapiens Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways Prostate cancer cells Protein Differential centrifugation Exosomes EVs
147 Vesiclepedia_2759 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Tangential flow filtration Exosomes Small EVs
148 Vesiclepedia_3132 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
149 Vesiclepedia_2321 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Lung epithelial cells miRNA Cell culture media exosome purification and RNA isolation Kit Exosomes Small EVs
150 Vesiclepedia_2426 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
151 Vesiclepedia_458 22740476 Homo sapiens Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4. Colorectal cancer cells Protein - Exosomes EVs
152 Vesiclepedia_55 12147373 Homo sapiens Malignant effusions and immunogenic tumour-derived exosomes. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
153 Vesiclepedia_493 23333927 Homo sapiens Characterization and proteomic analysis of ovarian cancer-derived exosomes. Ovarian cancer cells Protein - Exosomes EVs
154 Vesiclepedia_2499 34329193 Homo sapiens CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis Breast cancer cells miRNA Total Exosome Isolation Reagent Exosomes EVs
155 Vesiclepedia_2974 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Iodixanol density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
156 Vesiclepedia_2247 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
157 Vesiclepedia_717 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocytes Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
158 Vesiclepedia_2663 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
159 Vesiclepedia_2233 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
160 Vesiclepedia_771 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
161 Vesiclepedia_948 28819550 Mus musculus Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses. Bronchoalveolar lavage fluid Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
162 Vesiclepedia_489 23260141 Mus musculus Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration. Fibroblasts Protein - Exosomes EVs
163 Vesiclepedia_2743 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Breast cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
164 Vesiclepedia_2612 35443745 Homo sapiens Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts Colorectal cancer cells Protein
miRNA
Ultracentrifugation
ExoQuick Kit
Exosomes Small EVs
165 Vesiclepedia_3379 31848325 Rattus norvegicus Insulin-like growth factor-1 enchances neuroprotective effects of neural stem cell exosomes after spinal cord injury via an miR-219a-2-3p/YY1 mechanism Neural stem cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
166 Vesiclepedia_2911 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
167 Vesiclepedia_1079 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
168 Vesiclepedia_1832 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells miRNA Centrifugation
Filtration
ExoQuick Kit
Exosomes Small EVs
169 Vesiclepedia_877 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
170 Vesiclepedia_992 24434149 Homo sapiens In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Ovarian cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
171 Vesiclepedia_949 28819550 Mus musculus Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses. Bronchoalveolar lavage fluid Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
172 Vesiclepedia_898 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
173 Vesiclepedia_325 19289371 Homo sapiens Exosomal microRNA: a diagnostic marker for lung cancer Plasma miRNA Size exclusion chromatography
Immunobeads (EpCAM)
Exosomes EVs
174 Vesiclepedia_1284 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
175 Vesiclepedia_1270 24218614 Homo sapiens Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
176 Vesiclepedia_102 21082674 Homo sapiens Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
177 Vesiclepedia_3125 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Kidney cells Protein Differential centrifugation
Filtration
Sucrose density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
178 Vesiclepedia_142 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes EVs
179 Vesiclepedia_524 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophage Protein - Exosomes EVs
180 Vesiclepedia_425 21179422 Mus musculus Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. Mast cells mRNA - Exosomes/Nanovesicles EVs
181 Vesiclepedia_2987 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
182 Vesiclepedia_2497 34329193 Homo sapiens CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis Breast cancer cells Protein
miRNA
circRNA
Total Exosome Isolation Reagent Exosomes EVs
183 Vesiclepedia_13 15326289 Homo sapiens Identification and proteomic profiling of exosomes in human urine. Urine Protein Ultracentrifugation Exosomes EVs
184 Vesiclepedia_334 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Exosomes EVs
185 Vesiclepedia_108 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Ascites Protein
miRNA
Differential centrifugation
Sucrose density gradient
Immunobeads (EpCAM, CD24)
Exosomes EVs
186 Vesiclepedia_967 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
187 Vesiclepedia_344 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
188 Vesiclepedia_512 23533145 Homo sapiens In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Urine Protein - Exosomes/Microvesicles EVs
189 Vesiclepedia_2437 29335551 Homo sapiens Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Liver cancer cells Protein
miRNA
Filtration
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
190 Vesiclepedia_1258 24400796 Homo sapiens Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Aqueous humor Protein ExoQuick Exosomes EVs
191 Vesiclepedia_2351 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
192 Vesiclepedia_2746 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
193 Vesiclepedia_2648 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
194 Vesiclepedia_876 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
195 Vesiclepedia_2753 35173168 Homo sapiens Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
196 Vesiclepedia_3076 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
197 Vesiclepedia_993 24434149 Homo sapiens In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Ovarian cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
198 Vesiclepedia_790 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
199 Vesiclepedia_2429 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
200 Vesiclepedia_816 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
201 Vesiclepedia_3014 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
202 Vesiclepedia_14 16081791 Mus musculus Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism. Microglia Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
203 Vesiclepedia_2248 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
204 Vesiclepedia_1076 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
205 Vesiclepedia_2990 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
206 Vesiclepedia_3064 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Serum Protein Total Exosome isolation Kit Exosomes EVs
207 Vesiclepedia_3123 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Brain Protein Differential centrifugation
Filtration
Sucrose density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
208 Vesiclepedia_2644 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Mammary epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
209 Vesiclepedia_2342 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
210 Vesiclepedia_2468 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
211 Vesiclepedia_994 24434149 Homo sapiens In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Ovarian cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
212 Vesiclepedia_1365 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
213 Vesiclepedia_3276 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
214 Vesiclepedia_3151 34887361 Mus musculus Endothelial cell-derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway Endothelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
215 Vesiclepedia_656 28753793 Homo sapiens MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma. Serum miRNA Total Exosome Isolation Kit
Differential centrifugation
Ultracentrifugation
Immunobeads (EpCAM)
Exosomes EVs
216 Vesiclepedia_1204 27780738 Homo sapiens Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Serum miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
217 Vesiclepedia_990 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes/Microvesicles EVs
218 Vesiclepedia_1363 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
219 Vesiclepedia_24 11231627 Homo sapiens Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Melanoma cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
220 Vesiclepedia_1455 31949130 Homo sapiens circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma Lung cancer cells circRNA Total Exosome Isolation Reagent Exosomes Small EVs
221 Vesiclepedia_3071 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
222 Vesiclepedia_1 6307529 Ovis aries Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Reticulocytes Protein - Exosomes EVs
223 Vesiclepedia_1698 34108659 Mus musculus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Serum Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
224 Vesiclepedia_3147 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
225 Vesiclepedia_1667 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
226 Vesiclepedia_796 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
227 Vesiclepedia_2602 35351860 Homo sapiens Bone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5 Bone marrow mesenchymal stem cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
228 Vesiclepedia_470 23029346 Fasciola hepatica Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. Fasciola hepatica Protein - Exosomes/Extracellular vesicles/Microvesicles EVs
229 Vesiclepedia_481 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells Protein - Exosomes EVs
230 Vesiclepedia_742 28524762 Rattus norvegicus Exosomes promote restoration after an experimental animal model of intracerebral hemorrhage Mesenchymal stem cells Protein miRCURY Exosome Isolation Kit Exosomes EVs
231 Vesiclepedia_3411 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph miRNA Differential centrifugation
ExoQuick Kit
Exosomes Small EVs
232 Vesiclepedia_329 20304794 Homo sapiens Functional delivery of viral miRNAs via exosomes B cells miRNA Differential centrifugation Exosomes EVs
233 Vesiclepedia_3158 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
234 Vesiclepedia_217 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Serum Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
235 Vesiclepedia_2446 34489604 Mus musculus Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 Hepatocytes Protein
miRNA
Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
236 Vesiclepedia_3013 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
237 Vesiclepedia_214 21364924 Homo sapiens Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells T cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Exosomes EVs
238 Vesiclepedia_3156 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
239 Vesiclepedia_2255 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
240 Vesiclepedia_3077 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
241 Vesiclepedia_1355 32438511 Homo sapiens Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion Colorectal cancer cells Protein Differential centrifugation
Filtration
OptiPrep density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
242 Vesiclepedia_9 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. Macrophage Protein Differential centrifugation Exosomes EVs
243 Vesiclepedia_61 17133577 Mus musculus Association of citrullinated proteins with synovial exosomes. Synovial fluid Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
244 Vesiclepedia_725 25471207 Homo sapiens Intraluminal proteome and peptidome of human urinary extracellular vesicles. Urine Protein Differential centrifugation
Hydrostatic filtration dialysis
Ultrafiltration
Exosomes EVs
245 Vesiclepedia_1683 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
246 Vesiclepedia_2755 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
247 Vesiclepedia_2350 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Stromal vascular fraction miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
248 Vesiclepedia_3150 29438363 Homo sapiens CD9-positive exosomes from cancer-associated fibroblasts stimulate the migration ability of scirrhous-type gastric cancer cells Fibroblasts Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
249 Vesiclepedia_3122 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Brain Protein Differential centrifugation
Filtration
Sucrose density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
250 Vesiclepedia_1818 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
251 Vesiclepedia_3412 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph miRNA Differential centrifugation
ExoQuick Kit
Exosomes Small EVs
252 Vesiclepedia_2459 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
253 Vesiclepedia_792 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
254 Vesiclepedia_864 22046311 Mus musculus Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections Plasma Protein Differential centrifugation
Filtration
Sucrose density gradient
Ultracentrifugation
Exosomes EVs
255 Vesiclepedia_2641 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Cervical cancer cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
256 Vesiclepedia_1827 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells Protein
miRNA
Centrifugation
Filtration
ExoQuick Kit
Exosomes Small EVs
257 Vesiclepedia_1289 19912576 Homo sapiens HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Cervical cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
258 Vesiclepedia_809 29932869 Mus musculus Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy Schwann cells protein Filtration
Differential centrifugation
Ultracentrifugation
Exosomes EVs
259 Vesiclepedia_2668 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
260 Vesiclepedia_772 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
261 Vesiclepedia_3130 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
262 Vesiclepedia_2695 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage mRNA Total Exosome Isolation Reagent Exosomes Small EVs
263 Vesiclepedia_2766 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
264 Vesiclepedia_2029 35986010 Homo sapiens Exosomal miR-155-5p derived from glioma stem-like cells promotes mesenchymal transition via targeting ACOT12 Glioblastoma cells Protein
miRNA
Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
265 Vesiclepedia_3011 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
266 Vesiclepedia_522 23645497 Canis lupus familiaris Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Kidney cells Protein - Exosomes/Extracellular vesicles EVs
267 Vesiclepedia_1842 36408942 Homo sapiens Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
268 Vesiclepedia_3002 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
269 Vesiclepedia_2324 31807237 Homo sapiens Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
270 Vesiclepedia_741 25157233 Homo sapiens Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Placenta Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
271 Vesiclepedia_3028 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
272 Vesiclepedia_716 26317203 Homo sapiens Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis. Osteosarcoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
273 Vesiclepedia_998 24355714 Homo sapiens Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium. Leukemia cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
274 Vesiclepedia_1218 27872147 Homo sapiens Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
275 Vesiclepedia_903 25053844 Homo sapiens Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons Neuroblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
276 Vesiclepedia_1326 33431899 Homo sapiens High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces Protein
Lipid
Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
277 Vesiclepedia_764 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
278 Vesiclepedia_3019 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
279 Vesiclepedia_1933 36103526 Homo sapiens Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases Hepatic stellate cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
280 Vesiclepedia_101 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
281 Vesiclepedia_831 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
282 Vesiclepedia_803 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
283 Vesiclepedia_1080 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
284 Vesiclepedia_2662 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
285 Vesiclepedia_58 17700640 Homo sapiens CD24 is a marker of exosomes secreted into urine and amniotic fluid. Amniotic fluid Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
286 Vesiclepedia_1462 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells miRNA Differential centrifugation

Filtration
Ultracentrifugation
Exosomes Small EVs
287 Vesiclepedia_20 17956143 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer cells. Colorectal cancer cells Protein Differential centrifugation
Sucrose density gradient
Diafiltration
Exosomes EVs
288 Vesiclepedia_3286 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
289 Vesiclepedia_3060 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic duct epithelial cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
290 Vesiclepedia_2614 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
291 Vesiclepedia_1278 22437826 Drosophila melanogaster Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. Drosophila S2 cells Protein Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
292 Vesiclepedia_1016 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophage Protein
Lipids
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
293 Vesiclepedia_657 28753793 Homo sapiens MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma. Serum miRNA Total Exosome Isolation Kit
Differential centrifugation
Ultracentrifugation
Immunobeads (EpCAM)
Exosomes EVs
294 Vesiclepedia_3049 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Monocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
295 Vesiclepedia_3035 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
296 Vesiclepedia_1335 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice Plasma Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
297 Vesiclepedia_2474 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
298 Vesiclepedia_821 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose and deuterium oxide density cushion
Exosomes EVs
299 Vesiclepedia_3135 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
300 Vesiclepedia_3281 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
301 Vesiclepedia_3034 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
302 Vesiclepedia_3106 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
303 Vesiclepedia_480 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells Protein - Exosomes EVs
304 Vesiclepedia_2460 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
305 Vesiclepedia_3560 28409562 Homo sapiens Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation Colon cancer cells dsDNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
306 Vesiclepedia_659 29982104 Mus musculus NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo. Macrophage Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Exosomes EVs
307 Vesiclepedia_887 25102470 Homo sapiens Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
308 Vesiclepedia_3533 - Homo sapiens Small RNA Sequencing of Circulating Small Extracellular Vesicle MicroRNAs in Patients with Amyotrophic Lateral Sclerosis Serum miRNA ExoEasy Exosomes Small EVs
309 Vesiclepedia_1838 36408942 Rattus norvegicus Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Bone marrow mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
310 Vesiclepedia_189 21741384 Homo sapiens A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma Plasma Protein Differential centrifugation
Filtration
Exosomes EVs
311 Vesiclepedia_1141 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells Protein Differential centrifugation
Ultracentrifugation
Filtration
ExoQuick
Exosomes EVs
312 Vesiclepedia_1155 21212511 Homo sapiens Proteomic analysis of two types of exosomes in human whole saliva. Saliva Protein Differential centrifugation
Filtration
Ultracentrifugation
Gel filtration
Exosomes EVs
313 Vesiclepedia_2642 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Mammary epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
314 Vesiclepedia_882 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
315 Vesiclepedia_3197 34690112 Homo sapiens Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling Plasma Protein
lncRNA
ExoQuick Kit Exosomes EVs
316 Vesiclepedia_964 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
317 Vesiclepedia_1219 27872147 Homo sapiens Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
318 Vesiclepedia_2777 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
319 Vesiclepedia_2490 34388111 Homo sapiens miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Monocytic leukemia cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
320 Vesiclepedia_35 19367702 Rattus norvegicus Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. Hepatocytes Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes EVs
321 Vesiclepedia_538 23844026 Homo sapiens Characterization of human thymic exosomes. Thymus Protein - Exosomes EVs
322 Vesiclepedia_2000 34112803 Homo sapiens Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Plasma Protein Size exclusion chromatography
Centrifugal ultrafiltration
Exosomes Small EVs
323 Vesiclepedia_2634 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
324 Vesiclepedia_1658 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
325 Vesiclepedia_822 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
326 Vesiclepedia_2430 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
327 Vesiclepedia_1339 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice Liver miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
328 Vesiclepedia_444 22418980 Homo sapiens A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Urine Protein - Exosomes EVs
329 Vesiclepedia_33 21136642 Mus musculus Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Oligodendrocytes Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
330 Vesiclepedia_862 25776846 Homo sapiens Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens Epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
331 Vesiclepedia_143 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes EVs
332 Vesiclepedia_2748 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
333 Vesiclepedia_1449 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Plasma miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
334 Vesiclepedia_3006 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
335 Vesiclepedia_343 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
336 Vesiclepedia_2636 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
337 Vesiclepedia_2319 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Plasma Protein
small RNA
ExoQuick Kit Extracellular vesicles/Exosomes EVs
338 Vesiclepedia_2638 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Cervical cancer cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
339 Vesiclepedia_353 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
340 Vesiclepedia_333 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Exosomes EVs
341 Vesiclepedia_336 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Exosomes EVs
342 Vesiclepedia_1000 24079734 Mus musculus Immunostimulatory activity of murine keratinocyte-derived exosomes. Keratinocytes Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
343 Vesiclepedia_808 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
344 Vesiclepedia_3162 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
345 Vesiclepedia_3146 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
346 Vesiclepedia_2670 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
347 Vesiclepedia_1251 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
348 Vesiclepedia_835 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
349 Vesiclepedia_926 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
350 Vesiclepedia_897 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
351 Vesiclepedia_738 25157233 Homo sapiens Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Placenta choriocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
352 Vesiclepedia_2992 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
353 Vesiclepedia_44 19028452 Homo sapiens Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein. Plasma Protein Filtration
Size exclusion chromatography
Sucrose density gradient
Exosomes EVs
354 Vesiclepedia_1820 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
355 Vesiclepedia_3022 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
356 Vesiclepedia_2666 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
357 Vesiclepedia_1535 33589572 Homo sapiens Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis Lung cancer cells Protein Centrifugation
ExoQuick Kit
Exosomes Small EVs
358 Vesiclepedia_553 24009898 Mus musculus Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. Cardiomyocytes mRNA - Exosomes/Extracellular vesicles EVs
359 Vesiclepedia_238 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Ascites Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
360 Vesiclepedia_3058 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
361 Vesiclepedia_2997 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
362 Vesiclepedia_3406 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph Protein
miRNA
Differential centrifugation
ExoQuick Kit
Exosomes Small EVs
363 Vesiclepedia_18 11907077 Homo sapiens TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. T cells Protein Filtration
Ultracentrifugation
Exosomes EVs
364 Vesiclepedia_2 3597417 Ovis aries Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). Reticulocytes Protein
Lipids
Differential centrifugation Exosomes EVs
365 Vesiclepedia_3409 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph miRNA Differential centrifugation
ExoQuick Kit
Exosomes Small EVs
366 Vesiclepedia_1360 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
367 Vesiclepedia_126 - Homo sapiens Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? Mesenchymal stem cells Protein HPLC Exosomes EVs
368 Vesiclepedia_1116 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
369 Vesiclepedia_3584 24398677 Homo sapiens Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer Serum dsDNA-mutated Filtration
Ultracentrifugation
Exosomes Small EVs
370 Vesiclepedia_72 19801663 Homo sapiens Microenvironmental pH is a key factor for exosome traffic in tumor cells. Melanoma cells Protein
Lipids
Differential centrifugation Exosomes EVs
371 Vesiclepedia_215 21364924 Homo sapiens Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells B cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Exosomes EVs
372 Vesiclepedia_452 22506041 Mus musculus Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells. Cardiomyocytes mRNA - Exosomes/Membrane vesicles/Microvesicles/Prostasomes EVs
373 Vesiclepedia_915 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
374 Vesiclepedia_2280 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma miRNA Differential centrifugation
Polyethylene glycol-based precipitation
Centrifugation
Exosomes Small EVs
375 Vesiclepedia_1435 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
376 Vesiclepedia_1236 25421927 Heligmosomoides polygyrus Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Heligmosomoides polygyrus miRNA
Protein
Filtration
Ultracentrifugation
Exosomes EVs
377 Vesiclepedia_435 22031862 Mus musculus Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Dendritic cells miRNA - Exosomes/Nanovesicles EVs
378 Vesiclepedia_2439 29335551 Homo sapiens Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Liver cancer cells Protein
miRNA
Filtration
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
379 Vesiclepedia_140 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes EVs
380 Vesiclepedia_3283 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
381 Vesiclepedia_910 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
382 Vesiclepedia_1133 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Exosomes EVs
383 Vesiclepedia_121 21276792 Homo sapiens Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells. Trophoblast cells Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
384 Vesiclepedia_2353 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
385 Vesiclepedia_1134 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Exosomes EVs
386 Vesiclepedia_966 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
387 Vesiclepedia_2629 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
388 Vesiclepedia_1912 36270983 Mus musculus NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancer Lung cancer cells Protein Centrifugation
Exosome Isolation Reagent
Exosomes Small EVs
389 Vesiclepedia_419 21136642 Mus musculus Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Oligodendrocytes Protein - Exosomes EVs
390 Vesiclepedia_1004 23463506 Homo sapiens The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
391 Vesiclepedia_3540 35742955 Homo sapiens Genomic Analysis Made It Possible to Identify Gene-Driver Alterations Covering the Time Window between Diagnosis of Neuroblastoma 4S and the Progression to Stage 4 Plasma dsDNA Exo-RNeasy Kit Exosomes Small EVs
392 Vesiclepedia_2627 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
393 Vesiclepedia_1659 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
394 Vesiclepedia_53 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
395 Vesiclepedia_2428 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
396 Vesiclepedia_989 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes/Microvesicles EVs
397 Vesiclepedia_885 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
398 Vesiclepedia_10 11390481 Mus musculus Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. Dendritic cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
399 Vesiclepedia_1096 24976626 Homo sapiens Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells. Renal proximal tubule cells Protein Differential centrifugation
Ultracentrifugation
Immunoaffinity
Exosomes EVs
400 Vesiclepedia_323 20304794 Homo sapiens Functional delivery of viral miRNAs via exosomes B cells Protein Differential centrifugation Exosomes EVs
401 Vesiclepedia_988 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes/Microvesicles EVs
402 Vesiclepedia_2989 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
403 Vesiclepedia_1220 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Insulinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
404 Vesiclepedia_64 18520029 Homo sapiens Exosome-like vesicles with dipeptidyl peptidase IV in human saliva. Saliva Protein Filtration
Diafiltration
Gel filtration
Exosomes EVs
405 Vesiclepedia_86 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Colorectal cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
406 Vesiclepedia_878 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
407 Vesiclepedia_2756 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
408 Vesiclepedia_551 24009886 Homo sapiens Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Endothelial cells Protein - Exosomes/Extracellular vesicles EVs
409 Vesiclepedia_1821 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
410 Vesiclepedia_2246 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
411 Vesiclepedia_2232 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
412 Vesiclepedia_661 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
413 Vesiclepedia_2279 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma miRNA Differential centrifugation
Polyethylene glycol-based precipitation
Centrifugation
Exosomes Small EVs
414 Vesiclepedia_1545 33767144 Homo sapiens Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells Cervical cancer cells Protein Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
415 Vesiclepedia_1013 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophage Protein
Lipids
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
416 Vesiclepedia_134 15304316 Rattus norvegicus PLD2 is enriched on exosomes and its activity is correlated to the release of exosomes Basophilic leukemia cells Protein
Lipids
Differential centrifugation Exosomes EVs
417 Vesiclepedia_654 28290293 Bos taurus Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
418 Vesiclepedia_1571 33738083 Homo sapiens Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
419 Vesiclepedia_75 19381331 Homo sapiens High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. Plasma Protein Differential centrifugation Exosomes EVs
420 Vesiclepedia_549 24009881 Homo sapiens Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles/Ectosomes EVs
421 Vesiclepedia_107 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes EVs
422 Vesiclepedia_1262 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
423 Vesiclepedia_517 23585443 Homo sapiens Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Colorectal cancer cells Protein - Exosomes/Membrane vesicles EVs
424 Vesiclepedia_1092 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes EVs
425 Vesiclepedia_2343 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
426 Vesiclepedia_2770 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Size exclusion chromatography
Exosomes Small EVs
427 Vesiclepedia_45 18589210 Homo sapiens MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Serum Protein
miRNA
Ultracentrifugation
Immunobeads (EpCAM)
Exosomes EVs
428 Vesiclepedia_1008 23463506 Homo sapiens The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
429 Vesiclepedia_51 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
430 Vesiclepedia_1247 25167841 Homo sapiens Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Serum Protein CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips Exosomes EVs
431 Vesiclepedia_2317 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Plasma Protein
small RNA
ExoQuick Kit Extracellular vesicles/Exosomes EVs
432 Vesiclepedia_2249 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
433 Vesiclepedia_281 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells mRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
434 Vesiclepedia_1358 32438511 Homo sapiens Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion Colorectal cancer cells Protein Differential centrifugation
Filtration
OptiPrep density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
435 Vesiclepedia_1261 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
436 Vesiclepedia_1015 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophage Protein
Lipids
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
437 Vesiclepedia_42 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Bone marrow cells Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes EVs
438 Vesiclepedia_1452 31949130 Homo sapiens circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma Lung epithelial cells circRNA Total Exosome Isolation Reagent Exosomes Small EVs
439 Vesiclepedia_986 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes/Microvesicles EVs
440 Vesiclepedia_424 21179422 Mus musculus Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. Mast cells mRNA - Exosomes/Nanovesicles EVs
441 Vesiclepedia_36 19367702 Mus musculus Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. Hepatocytes Protein Differential centrifugation
Filtration
Exosomes EVs
442 Vesiclepedia_692 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Adipose-derived mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
443 Vesiclepedia_1523 33911067 Homo sapiens Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis Breast cancer cells circRNAs Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
444 Vesiclepedia_879 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
445 Vesiclepedia_1233 25469510 Homo sapiens GAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathways. Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
446 Vesiclepedia_3131 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
447 Vesiclepedia_1321 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces Lipid Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
448 Vesiclepedia_1052 29115712 Mus musculus Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
449 Vesiclepedia_132 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ovarian cancer cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes EVs
450 Vesiclepedia_1962 36417505 Homo sapiens A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER) Plasma Protein Acoustic nanoscale separation via wave-pillar excitation resonance (ANSWER) Exosomes Small EVs
451 Vesiclepedia_2296 29339034 Homo sapiens Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer Pancreatic duct fluid Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
452 Vesiclepedia_2767 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Ultracentrifugation
Exosomes Small EVs
453 Vesiclepedia_77 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
454 Vesiclepedia_904 25053844 Homo sapiens Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons Neuroblastoma cells miRNA Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
455 Vesiclepedia_3137 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
456 Vesiclepedia_117 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Dendritic cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
457 Vesiclepedia_2253 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
458 Vesiclepedia_2322 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Monocytes miRNA Cell culture media exosome purification and RNA isolation Kit Exosomes Small EVs
459 Vesiclepedia_1676 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
460 Vesiclepedia_1090 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes EVs
461 Vesiclepedia_1083 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
462 Vesiclepedia_2352 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Stromal vascular fraction miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
463 Vesiclepedia_17 11907077 Homo sapiens TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. T cells Protein Filtration
Ultracentrifugation
Exosomes EVs
464 Vesiclepedia_2005 34112803 Mus musculus Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Exosomes Small EVs
465 Vesiclepedia_2773 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Saliva Protein Filtration
Ultracentrifugation
Exosomes Small EVs
466 Vesiclepedia_2623 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
467 Vesiclepedia_818 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
468 Vesiclepedia_63 19056867 Homo sapiens Large-scale proteomics and phosphoproteomics of urinary exosomes. Urine Protein Differential centrifugation Exosomes EVs
469 Vesiclepedia_2637 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
470 Vesiclepedia_2764 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
471 Vesiclepedia_2320 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Lung epithelial cells miRNA Cell culture media exosome purification and RNA isolation Kit Exosomes Small EVs
472 Vesiclepedia_1830 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells miRNA Centrifugation
Filtration
ExoQuick Kit
Exosomes Small EVs
473 Vesiclepedia_487 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles EVs
474 Vesiclepedia_1332 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
475 Vesiclepedia_1522 33911067 Homo sapiens Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis Breast cancer cells circRNAs Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
476 Vesiclepedia_135 2777884 Cavia porcellus Asymmetric Distribution of Phospholipids in the Membrane of Vesicles Released During In Vitro Maturation of Guinea Pig Reticulocytes: Evidence Precluding a Role for Aminophospholipid Translocase Reticulocytes Proteins
Lipids
Differential centrifugation
Ultracentrifugation
Exosomes EVs
477 Vesiclepedia_1114 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
478 Vesiclepedia_2620 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
479 Vesiclepedia_710 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
480 Vesiclepedia_1275 23489476 Sus scrofa Boar seminal plasma exosomes: effect on sperm function and protein identification by sequencing. Seminal plasma Protein Differential centrifugation
Gel filtration
Ultracentrifugation
Exosomes EVs
481 Vesiclepedia_1841 36408942 Rattus norvegicus Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Bone marrow mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
482 Vesiclepedia_2665 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
483 Vesiclepedia_66 19199708 Homo sapiens Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Saliva Protein Differential centrifugation Exosomes EVs
484 Vesiclepedia_3148 29438363 Homo sapiens CD9-positive exosomes from cancer-associated fibroblasts stimulate the migration ability of scirrhous-type gastric cancer cells Fibroblasts Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
485 Vesiclepedia_787 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
486 Vesiclepedia_999 24355714 Homo sapiens Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium. Leukemia cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
487 Vesiclepedia_519 23585444 Homo sapiens Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. Malignant pleural effusions Protein - Exosomes/Microvesicles/Ectosomes/Microparticles EVs
488 Vesiclepedia_1671 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Exosomes Small EVs
489 Vesiclepedia_653 28290293 Homo sapiens Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Breast milk Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
490 Vesiclepedia_3054 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Plasma miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
491 Vesiclepedia_98 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
492 Vesiclepedia_1834 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells miRNA Centrifugation
Filtration
ExoQuick Kit
Exosomes Small EVs
493 Vesiclepedia_1264 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
494 Vesiclepedia_861 25776846 Homo sapiens Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens Epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
495 Vesiclepedia_1840 36408942 Rattus norvegicus Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Bone marrow mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
496 Vesiclepedia_1160 22641613 Homo sapiens Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
497 Vesiclepedia_2421 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
498 Vesiclepedia_2006 34112803 Mus musculus Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Exosomes Small EVs
499 Vesiclepedia_978 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes EVs
500 Vesiclepedia_1110 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
501 Vesiclepedia_1824 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Serum miRNA Total Exosome Isolation Kit Exosomes Small EVs
502 Vesiclepedia_1539 33658392 Homo sapiens Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma Lung epithelial cells miRNA Minute High-Efficiency Exosome Precipitation Reagent
Filtration
Exosomes Small EVs
503 Vesiclepedia_556 24069378 Homo sapiens Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression. Neuroblastoma cells Protein - Exosomes/Membrane vesicles EVs
504 Vesiclepedia_3575 31608233 Homo sapiens Double-Stranded DNA in Exosomes of Malignant Pleural Effusions as a Novel DNA Source for EGFR Mutation Detection in Lung Adenocarcinoma Pleural effusion dsDNA-mutated ExoQuick Kit Exosomes Small EVs
505 Vesiclepedia_2967 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
506 Vesiclepedia_3115 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Podocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
507 Vesiclepedia_441 22251860 Homo sapiens RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls. Serum mRNA - Exosomes/Microvesicles EVs
508 Vesiclepedia_927 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
509 Vesiclepedia_1120 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
ExoQuick
Exosomes EVs
510 Vesiclepedia_48 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. Breast milk Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes EVs
511 Vesiclepedia_1808 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells miRNA ExoQuick Kit Exosomes Small EVs
512 Vesiclepedia_2235 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
513 Vesiclepedia_788 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
514 Vesiclepedia_1112 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
515 Vesiclepedia_521 23645497 Canis lupus familiaris Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Kidney cells Protein - Exosomes/Extracellular vesicles EVs
516 Vesiclepedia_1253 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
517 Vesiclepedia_1548 33638284 Canis lupus familiaris Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition Kidney cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
518 Vesiclepedia_819 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
519 Vesiclepedia_1836 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells miRNA Centrifugation
Filtration
ExoQuick Kit
Exosomes Small EVs
520 Vesiclepedia_1290 19912576 Homo sapiens HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Lymphoblasts Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
521 Vesiclepedia_3368 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colon cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Exosomes Small EVs
522 Vesiclepedia_2240 36648227 Mus musculus Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Macrophage Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
523 Vesiclepedia_1150 22807456 Homo sapiens Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells. Lymphocytes Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
524 Vesiclepedia_23 11231627 Mus musculus Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Breast cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
525 Vesiclepedia_3577 35742955 Homo sapiens Genomic Analysis Made It Possible to Identify Gene-Driver Alterations Covering the Time Window between Diagnosis of Neuroblastoma 4S and the Progression to Stage 4 Plasma dsDNA-mutated Exo-RNeasy Kit Exosomes Small EVs
526 Vesiclepedia_349 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
527 Vesiclepedia_2283 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma miRNA Differential centrifugation
Polyethylene glycol-based precipitation
Centrifugation
Exosomes Small EVs
528 Vesiclepedia_832 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
529 Vesiclepedia_79 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 B cells Protein Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Exosomes EVs
530 Vesiclepedia_1999 34112803 Homo sapiens Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Exosomes Small EVs
531 Vesiclepedia_1094 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes EVs
532 Vesiclepedia_1527 33752173 Homo sapiens Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression Breast cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
533 Vesiclepedia_2619 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
534 Vesiclepedia_3414 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph miRNA Differential centrifugation
ExoQuick Kit
Exosomes Small EVs
535 Vesiclepedia_1825 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Serum miRNA Total Exosome Isolation Kit Exosomes Small EVs
536 Vesiclepedia_3119 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Kidney cells Protein Differential centrifugation
Filtration
Sucrose density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
537 Vesiclepedia_972 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes EVs
538 Vesiclepedia_2742 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Breast cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
539 Vesiclepedia_1325 33431899 Homo sapiens High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces Protein
Lipid
Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
540 Vesiclepedia_1109 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
541 Vesiclepedia_1536 33589572 Homo sapiens Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis Lung cancer cells Protein Centrifugation
ExoQuick Kit
Exosomes Small EVs
542 Vesiclepedia_1198 27883272 Homo sapiens Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. Serum miRNA
Metabolites
ExoQuick Exosomes EVs
543 Vesiclepedia_547 24009880 Homo sapiens Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. Mast cells miRNA - Exosomes/Extracellular vesicles EVs
544 Vesiclepedia_2470 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
545 Vesiclepedia_1246 25167841 Homo sapiens Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Serum Protein CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips Exosomes EVs
546 Vesiclepedia_1812 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum miRNA ExoQuick Kit Exosomes Small EVs
547 Vesiclepedia_689 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Adipose-derived mesenchymal stem cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
548 Vesiclepedia_70 19812188 Rattus norvegicus Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII. Dendritic cells Protein Differential centrifugation Exosomes EVs
549 Vesiclepedia_1697 34108659 Mus musculus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Monocyte/macrophage-like cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
550 Vesiclepedia_1146 23173708 Rattus norvegicus Wnt3a induces exosome secretion from primary cultured rat microglia. Primary microglial cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
551 Vesiclepedia_919 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
552 Vesiclepedia_1205 27780738 Homo sapiens Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Serum miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
553 Vesiclepedia_2425 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
554 Vesiclepedia_1434 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
555 Vesiclepedia_1276 23344851 Rattus norvegicus Urinary exosomes and diabetic nephropathy: a proteomic approach. Urine Protein Ultracentrifugation Exosomes EVs
556 Vesiclepedia_341 20615901 Homo sapiens Export of microRNAs and microRNA-protective protein by mammalian cells Epithelial cells miRNA Differential centrifugation Exosomes EVs
557 Vesiclepedia_1249 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
558 Vesiclepedia_2660 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
559 Vesiclepedia_1702 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Urine Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
560 Vesiclepedia_2030 35986010 Homo sapiens Exosomal miR-155-5p derived from glioma stem-like cells promotes mesenchymal transition via targeting ACOT12 Glial cells Protein
miRNA
Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
561 Vesiclepedia_1140 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells Protein Differential centrifugation
Ultracentrifugation
Filtration
ExoQuick
Exosomes EVs
562 Vesiclepedia_1108 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
563 Vesiclepedia_331 19627513 Homo sapiens Exosomes from human saliva as a source of microRNA biomarkers Saliva Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes EVs
564 Vesiclepedia_80 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 B cells Protein Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Exosomes EVs
565 Vesiclepedia_1806 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
566 Vesiclepedia_691 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Endometrium-derived mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
567 Vesiclepedia_900 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
568 Vesiclepedia_2635 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
569 Vesiclepedia_1244 25167841 Homo sapiens Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Serum Protein CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips Exosomes EVs
570 Vesiclepedia_474 23056502 Homo sapiens Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. Melanoma cells miRNA - Exosomes EVs
571 Vesiclepedia_896 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
572 Vesiclepedia_3129 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
573 Vesiclepedia_2250 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
574 Vesiclepedia_2278 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma miRNA Differential centrifugation
Polyethylene glycol-based precipitation
Centrifugation
Exosomes Small EVs
575 Vesiclepedia_1073 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
576 Vesiclepedia_3555 24398677 Homo sapiens Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer Serum dsDNA Ultracentrifugation Exosomes Small EVs
577 Vesiclepedia_2488 34388111 Homo sapiens miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Monocytic leukemia cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
578 Vesiclepedia_3 10545503 Mus musculus Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73. Dendritic cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
579 Vesiclepedia_26 19109410 Mus musculus Proteomic and immunologic analyses of brain tumor exosomes. Brain cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
580 Vesiclepedia_1081 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
581 Vesiclepedia_2761 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
582 Vesiclepedia_540 23886663 Homo sapiens LRRK2 Secretion in Exosomes is Regulated by 14-3-3. Urine Protein - Exosomes/Microvesicles EVs
583 Vesiclepedia_1451 31949130 Homo sapiens circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma Serum circRNA Total Exosome Isolation Kit Exosomes Small EVs
584 Vesiclepedia_3047 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Monocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
585 Vesiclepedia_3408 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph miRNA Differential centrifugation
ExoQuick Kit
Exosomes Small EVs
586 Vesiclepedia_2977 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Iodixanol density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
587 Vesiclepedia_1662 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker T lymphocytes Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
588 Vesiclepedia_68 19619303 Homo sapiens Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. Plasma Protein Differential centrifugation Exosomes EVs
589 Vesiclepedia_410 20052414 Homo sapiens Nanostructural and transcriptomic analyses of human saliva derived exosomes. Saliva mRNA - Exosomes/Membrane vesicles EVs
590 Vesiclepedia_2768 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Polyethylene glycol-based precipitation
Exosomes Small EVs
591 Vesiclepedia_2970 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
592 Vesiclepedia_2631 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
593 Vesiclepedia_3029 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
594 Vesiclepedia_753 29963269 Homo sapiens Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury Hepatoma cells miRNA Total Exosome Isolation Kit
Differential centrifugation
Exosomes EVs
595 Vesiclepedia_477 23056502 Homo sapiens Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. Melanoma cells mRNA - Exosomes EVs
596 Vesiclepedia_118 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Tabecular meshwork cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
597 Vesiclepedia_116 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. B cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
598 Vesiclepedia_2427 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
599 Vesiclepedia_92 20124479 Rattus norvegicus Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Pancreatic cancer cells Protein
mRNA
Differential centrifugation
Sucrose density gradient
Exosomes EVs
600 Vesiclepedia_1544 33767144 Homo sapiens Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells Cervical cancer cells Protein Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
601 Vesiclepedia_56 12147373 Homo sapiens Malignant effusions and immunogenic tumour-derived exosomes. Ascites Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
602 Vesiclepedia_37 10878338 Homo sapiens Direct immunosuppressive effects of EBV-encoded latent membrane protein 1. B cells Protein Differential centrifugation Exosomes EVs
603 Vesiclepedia_815 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
604 Vesiclepedia_2244 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
605 Vesiclepedia_40 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Plasma Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes EVs
606 Vesiclepedia_3066 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic duct epithelial cells Protein Total Exosome isolation Kit Exosomes EVs
607 Vesiclepedia_507 23511837 Homo sapiens Differential protein profiling of renal cell carcinoma urinary exosomes. Urine Protein - Exosomes/Nanovesicles EVs
608 Vesiclepedia_769 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
609 Vesiclepedia_2697 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage mRNA Total Exosome Isolation Reagent Exosomes Small EVs
610 Vesiclepedia_1678 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Exosomes Small EVs
611 Vesiclepedia_2524 34315885 Homo sapiens Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Urine Protein Centrifugation
Ultracentrifugation
Exosomes Small EVs
612 Vesiclepedia_806 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
613 Vesiclepedia_2443 34489604 Mus musculus Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 Hepatocytes Protein
miRNA
Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
614 Vesiclepedia_2667 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
615 Vesiclepedia_3030 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
616 Vesiclepedia_3069 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Serum Protein Total Exosome isolation Kit Exosomes EVs
617 Vesiclepedia_136 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes EVs
618 Vesiclepedia_1833 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells miRNA Centrifugation
Filtration
ExoQuick Kit
Exosomes Small EVs
619 Vesiclepedia_52 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
620 Vesiclepedia_97 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
621 Vesiclepedia_3143 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Plasma miRNA ExoQuick Kit Exosomes EVs
622 Vesiclepedia_902 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
623 Vesiclepedia_390 19158352 Homo sapiens Characterization of PKD protein-positive exosome-like vesicles. Urine Protein - Exosomes/Membrane particles EVs
624 Vesiclepedia_827 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
625 Vesiclepedia_3048 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Glial cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
626 Vesiclepedia_3398 31054213 Homo sapiens Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma Cholangiocarcinoma cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
627 Vesiclepedia_1007 23463506 Mus musculus The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
628 Vesiclepedia_2771 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Phosphatidylserine affinity purification
Exosomes Small EVs
629 Vesiclepedia_2254 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
630 Vesiclepedia_1538 33658392 Homo sapiens Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma Lung cancer cells Protein
miRNA
Minute High-Efficiency Exosome Precipitation Reagent
Filtration
Exosomes Small EVs
631 Vesiclepedia_1093 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes EVs
632 Vesiclepedia_492 23333927 Homo sapiens Characterization and proteomic analysis of ovarian cancer-derived exosomes. Ovarian cancer cells Protein - Exosomes EVs
633 Vesiclepedia_537 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells Protein - Exosomes/Microvesicles/Oncosomes/Microparticles EVs
634 Vesiclepedia_675 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Myeloid-derived suppressor cells Protein Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
635 Vesiclepedia_482 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells Protein - Exosomes EVs
636 Vesiclepedia_922 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
637 Vesiclepedia_1542 33767144 Homo sapiens Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells Cervical cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
638 Vesiclepedia_447 22444574 Homo sapiens Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry. Saliva Protein - Exosomes/Microvesicles EVs
639 Vesiclepedia_1525 33911067 Homo sapiens Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis Serum circRNAs Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
640 Vesiclepedia_2969 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
641 Vesiclepedia_3008 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
642 Vesiclepedia_1684 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
643 Vesiclepedia_2754 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
644 Vesiclepedia_430 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine Protein - Exosomes EVs
645 Vesiclepedia_2661 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
646 Vesiclepedia_437 22106071 Homo sapiens Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Urine Protein - Exosomes/Membrane vesicles EVs
647 Vesiclepedia_112 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Serum Protein
miRNA
Differential centrifugation
Sucrose density gradient
Exosomes EVs
648 Vesiclepedia_1118 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
649 Vesiclepedia_1936 36103526 Homo sapiens Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases Hepatic stellate cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
650 Vesiclepedia_756 28357077 Mus musculus Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells Plasma miRNA Total Exosome Isolation Kit
Differential centrifugation
Exosomes EVs
651 Vesiclepedia_3395 31792209 Homo sapiens Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
652 Vesiclepedia_676 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Myeloid-derived suppressor cells Protein Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
653 Vesiclepedia_2473 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
654 Vesiclepedia_916 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
655 Vesiclepedia_3120 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Kidney cells Protein Differential centrifugation
Filtration
Sucrose density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
656 Vesiclepedia_1809 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
657 Vesiclepedia_355 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Immunoaffinity (EpCAM)
Exosomes EVs
658 Vesiclepedia_106 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes EVs
659 Vesiclepedia_1461 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells miRNA Differential centrifugation

Filtration
Ultracentrifugation
Exosomes Small EVs
660 Vesiclepedia_1048 28725021 Bos taurus Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
661 Vesiclepedia_2639 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Cervical cancer cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
662 Vesiclepedia_1269 24218614 Homo sapiens Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
663 Vesiclepedia_913 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
664 Vesiclepedia_346 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
665 Vesiclepedia_2332 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
666 Vesiclepedia_105 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes EVs
667 Vesiclepedia_3082 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic duct epithelial cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
668 Vesiclepedia_1051 29115712 Mus musculus Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
669 Vesiclepedia_1137 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Exosomes EVs
670 Vesiclepedia_2618 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
671 Vesiclepedia_2971 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
672 Vesiclepedia_2985 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
673 Vesiclepedia_959 26196085 Homo sapiens Identification of prostate cancer biomarkers in urinary exosomes. Urine Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
674 Vesiclepedia_128 14965343 Homo sapiens Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization Dendritic cells Lipids Differential centrifugation
Ultracentrifugation
Exosomes EVs
675 Vesiclepedia_545 23983189 Homo sapiens Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. B cells Protein - Exosomes/Extracellular vesicles/Microvesicles EVs
676 Vesiclepedia_2750 35173168 Homo sapiens Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
677 Vesiclepedia_1203 27780738 Homo sapiens Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Serum miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
678 Vesiclepedia_784 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
679 Vesiclepedia_783 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
680 Vesiclepedia_789 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
681 Vesiclepedia_3065 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Serum Protein Total Exosome isolation Kit Exosomes EVs
682 Vesiclepedia_2489 34388111 Homo sapiens miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Monocytic leukemia cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
683 Vesiclepedia_1814 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum miRNA ExoQuick Kit Exosomes Small EVs
684 Vesiclepedia_1152 22057275 Homo sapiens Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. Neuroblastoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
685 Vesiclepedia_100 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
686 Vesiclepedia_1124 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
ExoQuick
Exosomes EVs
687 Vesiclepedia_1333 33368224 Homo sapiens Colorectal cancer prompted adipose tissue browning and cancer cachexia through transferring exosomal miR-146b-5p Intestinal epithelial cells Protein
mRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
688 Vesiclepedia_1433 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
689 Vesiclepedia_2442 34489604 Mus musculus Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 Hepatocytes Protein
miRNA
Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
690 Vesiclepedia_1690 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
691 Vesiclepedia_1328 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Plasma Lipid Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
692 Vesiclepedia_1674 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
693 Vesiclepedia_3580 26530043 Homo sapiens Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression Serum mtDNA-mutated ExoQuick exosome precipitation solution Exosomes Small EVs
694 Vesiclepedia_345 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
695 Vesiclepedia_3056 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
696 Vesiclepedia_16 9685355 Homo sapiens Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. B cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
697 Vesiclepedia_2630 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
698 Vesiclepedia_3401 31054213 Homo sapiens Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma Cholangiocarcinoma cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
699 Vesiclepedia_535 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells Protein - Exosomes/Microvesicles/Oncosomes/Microparticles EVs
700 Vesiclepedia_1463 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells miRNA Differential centrifugation

Filtration
Ultracentrifugation
Exosomes Small EVs
701 Vesiclepedia_812 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
702 Vesiclepedia_1075 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
703 Vesiclepedia_2339 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
704 Vesiclepedia_60 17700640 Mus musculus CD24 is a marker of exosomes secreted into urine and amniotic fluid. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
705 Vesiclepedia_963 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
706 Vesiclepedia_187 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Serum Protein Differential centrifugation
ExoQuick
Exosomes EVs
707 Vesiclepedia_1469 32132543 Homo sapiens Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension Pulmonary artery endothelial cells miRNA miRCURY Exosome Isolation Kit
Centrifugation
Sonication
Exosomes Small EVs
708 Vesiclepedia_987 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes/Microvesicles EVs
709 Vesiclepedia_1327 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Plasma Lipid Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
710 Vesiclepedia_2337 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Plasma miRNA ExoQuick Kit
Centrifugation
Exosomes Small EVs
711 Vesiclepedia_1121 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
ExoQuick
Exosomes EVs
712 Vesiclepedia_2004 34112803 Mus musculus Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Exosomes Small EVs
713 Vesiclepedia_388 18570454 Homo sapiens Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry. Neural stem cells Protein - Exosomes/Membrane vesicles EVs
714 Vesiclepedia_2277 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma miRNA Differential centrifugation
Polyethylene glycol-based precipitation
Centrifugation
Exosomes Small EVs
715 Vesiclepedia_3269 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
716 Vesiclepedia_1828 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells Protein
miRNA
Centrifugation
Filtration
ExoQuick Kit
Exosomes Small EVs
717 Vesiclepedia_2625 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
718 Vesiclepedia_1104 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
719 Vesiclepedia_69 19812188 Rattus norvegicus Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII. Dendritic cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
720 Vesiclepedia_1934 36103526 Homo sapiens Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases Hepatic stellate cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
721 Vesiclepedia_1680 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
722 Vesiclepedia_1157 20662102 Mus musculus Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages. Macrophage Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
723 Vesiclepedia_760 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
724 Vesiclepedia_3399 31054213 Homo sapiens Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma Cholangiocarcinoma cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
725 Vesiclepedia_1530 33752173 Homo sapiens Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression Breast cancer cells miRNA Total Exosome Isolation Kit
Centrifugation
Exosomes Small EVs
726 Vesiclepedia_838 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
727 Vesiclepedia_2613 35443745 Homo sapiens Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts Colorectal cancer cells Protein
miRNA
Ultracentrifugation
ExoQuick Kit
Exosomes Small EVs
728 Vesiclepedia_2335 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
729 Vesiclepedia_724 25471207 Homo sapiens Intraluminal proteome and peptidome of human urinary extracellular vesicles. Urine Protein Differential centrifugation
Hydrostatic filtration dialysis
Ultrafiltration
Exosomes EVs
730 Vesiclepedia_1020 21734072 Mus musculus Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice. Insulinoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
731 Vesiclepedia_1660 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic duct epithelial cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
732 Vesiclepedia_2607 36581340 Homo sapiens Rab27b, a Regulator of Exosome Secretion, Is Associated With Peritoneal Metastases in Gastric Cancer Gastric cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
733 Vesiclepedia_2469 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
734 Vesiclepedia_411 20124223 Homo sapiens Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Squamous carcinoma cells Protein - Exosomes EVs
735 Vesiclepedia_2463 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
736 Vesiclepedia_1368 32132711 Mus musculus Decoy exosomes provide protection against bacterial toxins Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
737 Vesiclepedia_826 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
738 Vesiclepedia_2669 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
739 Vesiclepedia_3070 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
740 Vesiclepedia_2242 36648227 Mus musculus Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Macrophage Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
741 Vesiclepedia_94 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
742 Vesiclepedia_2445 34489604 Mus musculus Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 Hepatocytes Protein
miRNA
Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
743 Vesiclepedia_2991 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
744 Vesiclepedia_1216 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
745 Vesiclepedia_3068 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Serum Protein Total Exosome isolation Kit Exosomes EVs
746 Vesiclepedia_550 24009881 Homo sapiens Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles/Ectosomes EVs
747 Vesiclepedia_3112 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
748 Vesiclepedia_3057 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
749 Vesiclepedia_1149 22807456 Homo sapiens Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells. Lymphocytes Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
750 Vesiclepedia_667 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid miRNA Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
751 Vesiclepedia_3271 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
752 Vesiclepedia_1072 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
753 Vesiclepedia_1336 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice Plasma Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
754 Vesiclepedia_754 29963269 Homo sapiens Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury Hepatoma cells Protein Total Exosome Isolation Kit
Differential centrifugation
Exosomes EVs
755 Vesiclepedia_62 17133577 Mus musculus Association of citrullinated proteins with synovial exosomes. Synovial fluid Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
756 Vesiclepedia_1695 34108659 Mus musculus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
757 Vesiclepedia_863 22046311 Mus musculus Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
758 Vesiclepedia_1533 33589572 Homo sapiens Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis Plasma Protein
lncRNA
Centrifugation
ExoQuick Kit
Exosomes Small EVs
759 Vesiclepedia_122 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Saliva Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
760 Vesiclepedia_2973 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
761 Vesiclepedia_2916 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
762 Vesiclepedia_1653 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Glioblastoma cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
763 Vesiclepedia_19 16302729 Homo sapiens Purification, characterization and biological significance of tumor-derived exosomes. Breast cancer cells Protein Differential centrifugation
Sucrose density gradient
Filtration
Immunobeads(HER2)
Exosomes EVs
764 Vesiclepedia_2325 31807237 Homo sapiens Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
765 Vesiclepedia_2649 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
766 Vesiclepedia_1568 33738083 Homo sapiens Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
767 Vesiclepedia_2241 36648227 Mus musculus Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Macrophage Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
768 Vesiclepedia_763 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
769 Vesiclepedia_1014 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophage Protein
Lipids
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
770 Vesiclepedia_1996 34112803 Mus musculus Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Exosomes Small EVs
771 Vesiclepedia_3012 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
772 Vesiclepedia_1468 32132543 Homo sapiens Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension Pulmonary artery endothelial cells miRNA miRCURY Exosome Isolation Kit
Centrifugation
Sonication
Exosomes Small EVs
773 Vesiclepedia_1017 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophage Protein
Lipids
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
774 Vesiclepedia_2915 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
775 Vesiclepedia_3144 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Plasma miRNA ExoQuick Kit Exosomes EVs
776 Vesiclepedia_766 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
777 Vesiclepedia_3568 27684368 Homo sapiens Indication of Horizontal DNA Gene Transfer by Extracellular Vesicles Mesenchymal stem cells dsDNA Differential centrifugation
Ultracentrifugation
Exosomes|Microvesicles EVs
778 Vesiclepedia_1686 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Exosomes Small EVs
779 Vesiclepedia_2760 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
780 Vesiclepedia_929 25483805 Gallus gallus Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Notochord cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
781 Vesiclepedia_1656 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Glioblastoma cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
782 Vesiclepedia_1005 23463506 Homo sapiens The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
783 Vesiclepedia_735 25285581 Mus musculus Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells. Myeloid-derived suppressor cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
784 Vesiclepedia_3164 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
785 Vesiclepedia_1447 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
786 Vesiclepedia_2422 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
787 Vesiclepedia_1694 34108659 Mus musculus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Melanoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
788 Vesiclepedia_1679 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
789 Vesiclepedia_7 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. Mast cells Protein Differential centrifugation Exosomes EVs
790 Vesiclepedia_658 28753793 Homo sapiens MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma. Serum miRNA Total Exosome Isolation Kit
Differential centrifugation
Ultracentrifugation
Immunobeads (EpCAM)
Exosomes EVs
791 Vesiclepedia_451 22451062 Homo sapiens A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: application to RCC urinary exosomes. Urine Lipids - Exosomes EVs
792 Vesiclepedia_1699 34108659 Bos taurus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Serum Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
793 Vesiclepedia_131 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ascites Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes EVs
794 Vesiclepedia_2694 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage Protein
mRNA
Total Exosome Isolation Reagent Exosomes Small EVs
795 Vesiclepedia_1106 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
796 Vesiclepedia_96 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
797 Vesiclepedia_761 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
798 Vesiclepedia_1681 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
799 Vesiclepedia_1283 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
800 Vesiclepedia_2664 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
801 Vesiclepedia_2763 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
802 Vesiclepedia_50 14582906 Homo sapiens Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. Dendritic cells Protein Differential centrifugation
Immunobeads (EpCAM)
Exosomes EVs
803 Vesiclepedia_109 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Malignant pleural effusions Protein
miRNA
Differential centrifugation
Sucrose density gradient
Immunobeads (EpCAM)
Exosomes EVs
804 Vesiclepedia_146 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes EVs
805 Vesiclepedia_1046 28725021 Bos taurus Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
806 Vesiclepedia_1097 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. adipocytes Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
807 Vesiclepedia_865 22046311 Mus musculus Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections Reticulocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
808 Vesiclepedia_73 18494037 Mus musculus Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes. Embryonic fibroblasts Protein Differential centrifugation Exosomes EVs
809 Vesiclepedia_2341 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
810 Vesiclepedia_1813 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum miRNA ExoQuick Kit Exosomes Small EVs
811 Vesiclepedia_27 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Medulloblastoma cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
812 Vesiclepedia_2251 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
813 Vesiclepedia_1234 25421927 Mus musculus Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Serum miRNA
Protein
Filtration
Ultracentrifugation
Exosomes EVs
814 Vesiclepedia_43 17076679 Homo sapiens Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences. Plasma Protein Size exclusion chromatography
Ultracentrifugation
Immunobeads (CD3, CD19, CD56, CD83, PLAP)
Exosomes EVs
815 Vesiclepedia_38 15210972 Oryctolagus cuniculus Cells release prions in association with exosomes. Epithelial cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
816 Vesiclepedia_1197 27883272 Homo sapiens Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. Plasma miRNA
Metabolites
ExoQuick Exosomes EVs
817 Vesiclepedia_3107 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
818 Vesiclepedia_1432 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
819 Vesiclepedia_674 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophage Protein Microfiltration
Differential centrifugation
Ultracentrifugation
Exosomes EVs
820 Vesiclepedia_3004 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
821 Vesiclepedia_8 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. B cells Protein Differential centrifugation Exosomes EVs
822 Vesiclepedia_982 25458527 Homo sapiens Benchtop isolation and characterization of functional exosomes by sequential filtration Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
823 Vesiclepedia_2472 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
824 Vesiclepedia_2698 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage mRNA Total Exosome Isolation Reagent Exosomes Small EVs
825 Vesiclepedia_1438 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
826 Vesiclepedia_539 23853596 Trichomonas vaginalis Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions. Trichomonas vaginalis Protein - Exosomes/Microvesicles EVs
827 Vesiclepedia_1675 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
828 Vesiclepedia_1998 34112803 Homo sapiens Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Exosomes Small EVs
829 Vesiclepedia_3285 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
830 Vesiclepedia_2741 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
831 Vesiclepedia_3117 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Brain Protein Differential centrifugation
Filtration
Sucrose density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
832 Vesiclepedia_2654 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
833 Vesiclepedia_3126 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Kidney cells Protein Differential centrifugation
Filtration
Sucrose density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
834 Vesiclepedia_190 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Follicular fluid miRNA Differential centrifugation
ExoQuick
Exosomes EVs
835 Vesiclepedia_1441 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
836 Vesiclepedia_1126 24295599 Mus musculus Exosomes from myeloid-derived suppressor cells carry biologically active proteins. Myeloid-derived suppressor cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
837 Vesiclepedia_347 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
838 Vesiclepedia_95 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
839 Vesiclepedia_2236 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
840 Vesiclepedia_1119 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
841 Vesiclepedia_439 22129587 Bos taurus Bovine milk exosome proteome. Bovine milk Protein - Exosomes/Membrane vesicles EVs
842 Vesiclepedia_1107 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
843 Vesiclepedia_113 21557262 Homo sapiens Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
844 Vesiclepedia_12 15478216 Homo sapiens Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry. Melanoma cells Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
845 Vesiclepedia_332 19627513 Homo sapiens Exosomes from human saliva as a source of microRNA biomarkers Saliva miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
846 Vesiclepedia_1437 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
847 Vesiclepedia_1816 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum miRNA ExoQuick Kit Exosomes Small EVs
848 Vesiclepedia_5 11145662 Mus musculus Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes. Mast cells Protein Differential centrifugation Exosomes EVs
849 Vesiclepedia_2601 35351860 Homo sapiens Bone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5 Bone marrow mesenchymal stem cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
850 Vesiclepedia_2996 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
851 Vesiclepedia_3199 34690112 Homo sapiens Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling Ovarian cancer cells Protein ExoQuick Kit Exosomes EVs
852 Vesiclepedia_752 29963269 Homo sapiens Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury Hepatoma cells Protein Total Exosome Isolation Kit
Differential centrifugation
Exosomes EVs
853 Vesiclepedia_2328 31807237 Homo sapiens Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
854 Vesiclepedia_1019 21734072 Mus musculus Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice. Insulinoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
855 Vesiclepedia_534 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells Protein - Exosomes/Microvesicles/Oncosomes/Microparticles EVs
856 Vesiclepedia_2229 36648227 Mus musculus Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Macrophage Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
857 Vesiclepedia_3075 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
858 Vesiclepedia_1689 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
859 Vesiclepedia_1450 31949130 Homo sapiens circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma Serum circRNA Total Exosome Isolation Kit Exosomes Small EVs
860 Vesiclepedia_114 21557262 Homo sapiens Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
861 Vesiclepedia_145 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes EVs
862 Vesiclepedia_2744 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
863 Vesiclepedia_2027 36455873 Homo sapiens Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF Plasma Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
864 Vesiclepedia_2237 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
865 Vesiclepedia_881 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
866 Vesiclepedia_1526 33479185 Homo sapiens Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke Mesenchymal stem cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
867 Vesiclepedia_2988 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
868 Vesiclepedia_2500 34329193 Homo sapiens CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis Breast cancer cells miRNA Total Exosome Isolation Reagent Exosomes EVs
869 Vesiclepedia_357 24352158 Homo sapiens Characterization and deep sequencing analysis of exosomal miRNA in human urine Urine miRNA Differential centrifugation
Norgen Biotek Exosome kit
Exosomes EVs
870 Vesiclepedia_781 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
871 Vesiclepedia_3140 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Plasma Protein
miRNA
ExoQuick Kit Exosomes EVs
872 Vesiclepedia_801 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
873 Vesiclepedia_2002 34112803 Homo sapiens Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Plasma Protein Size exclusion chromatography
Centrifugal ultrafiltration
Exosomes Small EVs
874 Vesiclepedia_2653 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
875 Vesiclepedia_3152 34887361 Mus musculus Endothelial cell-derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway Endothelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
876 Vesiclepedia_2749 35173168 Homo sapiens Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
877 Vesiclepedia_67 19619303 Homo sapiens Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. Ovarian cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
878 Vesiclepedia_2650 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
879 Vesiclepedia_1162 22641613 Homo sapiens Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
880 Vesiclepedia_1287 20880880 Homo sapiens Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis. Bronchoalveolar lavage fluid Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
881 Vesiclepedia_478 23082778 Homo sapiens Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Urine Protein - Exosomes/Membrane vesicles EVs
882 Vesiclepedia_3154 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
883 Vesiclepedia_976 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes EVs
884 Vesiclepedia_513 23533145 Homo sapiens In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Urine Protein - Exosomes/Microvesicles EVs
885 Vesiclepedia_828 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
886 Vesiclepedia_1528 33752173 Homo sapiens Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression Breast cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
887 Vesiclepedia_2323 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Monocytes miRNA Cell culture media exosome purification and RNA isolation Kit Exosomes Small EVs
888 Vesiclepedia_3200 34690112 Homo sapiens Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling Ovarian cancer cells Protein ExoQuick Kit Exosomes EVs
889 Vesiclepedia_824 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
890 Vesiclepedia_2234 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
891 Vesiclepedia_1566 33523942 Homo sapiens Exosomal delivery of NF-κB inhibitor delays LPS-induced preterm birth and modulates fetal immune cell profile in mouse models Embryonic kidney cells Protein Centrifugation
Filtration
Size exclusion chromatography
Exosomes Small EVs
892 Vesiclepedia_340 20615901 Homo sapiens Export of microRNAs and microRNA-protective protein by mammalian cells Lung cancer cells miRNA Differential centrifugation Exosomes EVs
893 Vesiclepedia_59 17700640 Mus musculus CD24 is a marker of exosomes secreted into urine and amniotic fluid. Amniotic fluid Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
894 Vesiclepedia_3277 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
895 Vesiclepedia_3380 31848325 Rattus norvegicus Insulin-like growth factor-1 enchances neuroprotective effects of neural stem cell exosomes after spinal cord injury via an miR-219a-2-3p/YY1 mechanism Neural stem cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
896 Vesiclepedia_817 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
897 Vesiclepedia_199 21609964 Homo sapiens Characterization of extracellular circulating microRNA Plasma Protein Differential centrifugation
Filtration
Exosomes EVs
898 Vesiclepedia_133 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ovarian cancer cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes EVs
899 Vesiclepedia_548 24009880 Homo sapiens Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. Mast cells mRNA - Exosomes/Extracellular vesicles EVs
900 Vesiclepedia_392 19351151 Mus musculus Characterization of vesicles secreted from insulinoma NIT-1 cells. Pancreatic cells Protein - Exosomes EVs
901 Vesiclepedia_830 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
902 Vesiclepedia_1687 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
903 Vesiclepedia_811 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
904 Vesiclepedia_3067 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Total Exosome isolation Kit Exosomes EVs
905 Vesiclepedia_129 14965343 Rattus norvegicus Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization Tumoral mast cells Lipids Differential centrifugation
Ultracentrifugation
Exosomes EVs
906 Vesiclepedia_3145 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Plasma miRNA ExoQuick Kit Exosomes EVs
907 Vesiclepedia_3134 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
908 Vesiclepedia_2626 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
909 Vesiclepedia_1444 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
910 Vesiclepedia_82 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Stomach cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
911 Vesiclepedia_479 23082778 Homo sapiens Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Urine Protein - Exosomes/Membrane vesicles EVs
912 Vesiclepedia_1693 34108659 Mus musculus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
913 Vesiclepedia_398 19530224 Homo sapiens Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. Keratinocytes Protein - Exosomes EVs
914 Vesiclepedia_1666 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
915 Vesiclepedia_483 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Epimastigotes Protein - Exosomes/Extracellular vesicles/Ectosomes EVs
916 Vesiclepedia_947 28819550 Mus musculus Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses. Bronchoalveolar lavage fluid Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
917 Vesiclepedia_1823 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Serum miRNA Total Exosome Isolation Kit Exosomes Small EVs
918 Vesiclepedia_1122 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
ExoQuick
Exosomes EVs
919 Vesiclepedia_1670 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Monocytic leukemia cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
920 Vesiclepedia_342 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
921 Vesiclepedia_1524 33911067 Homo sapiens Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis Serum circRNAs Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
922 Vesiclepedia_2655 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
923 Vesiclepedia_476 23056502 Homo sapiens Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. Melanoma cells miRNA - Exosomes EVs
924 Vesiclepedia_762 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
925 Vesiclepedia_3063 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Serum Protein Total Exosome isolation Kit Exosomes EVs
926 Vesiclepedia_1045 28725021 Bos taurus Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
927 Vesiclepedia_374 18039940 Cryptococcus neoformans Extracellular vesicles produced by Cryptococcus neoformans contain protein components associated with virulence. Cryptococcus neoformans Protein - Exosomes/Extracellular vesicles EVs
928 Vesiclepedia_1467 32132543 Homo sapiens Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension Pulmonary artery endothelial cells Protein miRCURY Exosome Isolation Kit
Centrifugation
Sonication
Exosomes Small EVs
929 Vesiclepedia_2772 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Saliva Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
930 Vesiclepedia_1136 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Exosomes EVs
931 Vesiclepedia_1815 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum miRNA ExoQuick Kit Exosomes Small EVs
932 Vesiclepedia_330 20304794 Homo sapiens Functional delivery of viral miRNAs via exosomes B cells miRNA Differential centrifugation Exosomes EVs
933 Vesiclepedia_3250 34545097 Homo sapiens Exosome-mediated stable epigenetic repression of HIV-1 Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
934 Vesiclepedia_2615 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
935 Vesiclepedia_2462 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
936 Vesiclepedia_2981 30089911 Mus musculus Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
937 Vesiclepedia_1125 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
ExoQuick
Exosomes EVs
938 Vesiclepedia_883 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
939 Vesiclepedia_498 23376485 Homo sapiens Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Urine Protein - Exosomes/Membrane vesicles EVs
940 Vesiclepedia_718 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
941 Vesiclepedia_3031 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
942 Vesiclepedia_115 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. T cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
943 Vesiclepedia_3552 31555514 Homo sapiens Liquid biopsies using pleural effusion-derived exosomal DNA in advanced lung adenocarcinoma Pleural effusion dsDNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
944 Vesiclepedia_780 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
945 Vesiclepedia_1144 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells Protein Differential centrifugation
Ultracentrifugation
Filtration
ExoQuick
Exosomes EVs
946 Vesiclepedia_1077 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma miRNA Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
947 Vesiclepedia_2774 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Saliva Protein Filtration
Polyethylene glycol-based precipitation
Exosomes Small EVs
948 Vesiclepedia_2346 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
949 Vesiclepedia_3543 26530043 Homo sapiens Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression Serum mtDNA ExoQuick exosome precipitation solution Exosomes Small EVs
950 Vesiclepedia_15 17486113 Mus musculus
Homo sapiens
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Mast cells Protein
mRNA
miRNA
Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
951 Vesiclepedia_46 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. Breast milk Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes EVs
952 Vesiclepedia_1123 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
ExoQuick
Exosomes EVs
953 Vesiclepedia_2628 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
954 Vesiclepedia_2910 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
955 Vesiclepedia_1259 24400796 Rattus norvegicus Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Retinal glial cells Protein ExoQuick Exosomes EVs
956 Vesiclepedia_1196 27883272 Homo sapiens Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. Plasma miRNA
Metabolites
ExoQuick Exosomes EVs
957 Vesiclepedia_1256 24400796 Homo sapiens Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Retinal pigment epithelial cells Protein ExoQuick Exosomes EVs
958 Vesiclepedia_2975 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Iodixanol density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
959 Vesiclepedia_1500 33982667 Homo sapiens Exosomal circRNA 0001445 promotes glioma progression through miRNA-127-5p/SNX5 pathway Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
960 Vesiclepedia_71 19801663 Homo sapiens Microenvironmental pH is a key factor for exosome traffic in tumor cells. Melanoma cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes EVs
961 Vesiclepedia_1668 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pluripotent stem cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
962 Vesiclepedia_2752 35173168 Homo sapiens Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
963 Vesiclepedia_671 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophage Protein Microfiltration
Differential centrifugation
Ultracentrifugation
Exosomes EVs
964 Vesiclepedia_1082 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
965 Vesiclepedia_1669 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Lymphoma cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
966 Vesiclepedia_1439 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
967 Vesiclepedia_124 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Breast milk Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
968 Vesiclepedia_123 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
969 Vesiclepedia_797 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
970 Vesiclepedia_2647 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
971 Vesiclepedia_2467 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
972 Vesiclepedia_2658 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
973 Vesiclepedia_2995 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
974 Vesiclepedia_337 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells miRNA Differential centrifugation
Filtration
Exosomes EVs
975 Vesiclepedia_120 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Aqueous humor Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
976 Vesiclepedia_1367 32132711 Mus musculus Decoy exosomes provide protection against bacterial toxins Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
977 Vesiclepedia_2420 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
978 Vesiclepedia_3127 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
979 Vesiclepedia_1532 33752173 Homo sapiens Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression Plasma miRNA Total Exosome Isolation Kit
Centrifugation
Exosomes Small EVs
980 Vesiclepedia_755 29963269 Homo sapiens Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury Hepatoma cells miRNA Total Exosome Isolation Kit
Differential centrifugation
Exosomes EVs
981 Vesiclepedia_2645 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Mammary epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
982 Vesiclepedia_1022 19665478 Salmo salar CpG-induced secretion of MHCIIbeta and exosomes from salmon (Salmo salar) APCs. Head kidney leukocytes Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
983 Vesiclepedia_436 22031862 Mus musculus Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Dendritic cells miRNA - Exosomes/Nanovesicles EVs
984 Vesiclepedia_1811 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
985 Vesiclepedia_2605 36581340 Homo sapiens Rab27b, a Regulator of Exosome Secretion, Is Associated With Peritoneal Metastases in Gastric Cancer Gastric cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
986 Vesiclepedia_757 28357077 Mus musculus Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells Plasma miRNA Total Exosome Isolation Kit
Differential centrifugation
Exosomes EVs
987 Vesiclepedia_1341 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice Muscle miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
988 Vesiclepedia_453 22635005 Homo sapiens Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Melanoma cells Protein - Exosomes EVs
989 Vesiclepedia_3402 31054213 Homo sapiens Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma Cholangiocarcinoma cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
990 Vesiclepedia_3124 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Kidney cells Protein Differential centrifugation
Filtration
Sucrose density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
991 Vesiclepedia_1322 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces Lipid Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
992 Vesiclepedia_91 21252909 Homo sapiens Diacylglycerol kinase a regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes T cells Protein
Lipids
Differential centrifugation
Ultracentrifugation
Exosomes EVs
993 Vesiclepedia_1148 23173708 Rattus norvegicus Wnt3a induces exosome secretion from primary cultured rat microglia. Primary microglial cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
994 Vesiclepedia_90 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
995 Vesiclepedia_2769 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Membrane affinity purification
Exosomes Small EVs
996 Vesiclepedia_2297 29339034 Homo sapiens Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer Pancreatic duct fluid Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
997 Vesiclepedia_1078 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma miRNA Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
998 Vesiclepedia_1810 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells miRNA ExoQuick Kit Exosomes Small EVs
999 Vesiclepedia_677 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Dendritic cells Protein Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1000 Vesiclepedia_1153 22057275 Homo sapiens Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. Neuroblastoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1001 Vesiclepedia_860 25776846 Homo sapiens Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens Epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1002 Vesiclepedia_2424 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1003 Vesiclepedia_1324 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces Protein
Lipid
miRNA
Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
1004 Vesiclepedia_3252 34545097 Homo sapiens Exosome-mediated stable epigenetic repression of HIV-1 Embryonic kidney cells Protein
mRNA
Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
1005 Vesiclepedia_1829 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells miRNA Centrifugation
Filtration
ExoQuick Kit
Exosomes Small EVs
1006 Vesiclepedia_1703 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1007 Vesiclepedia_488 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles EVs
1008 Vesiclepedia_1012 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophage Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles/Exosomes EVs
1009 Vesiclepedia_971 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes EVs
1010 Vesiclepedia_834 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
1011 Vesiclepedia_3198 34690112 Homo sapiens Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling Plasma Protein
lncRNA
ExoQuick Kit Exosomes EVs
1012 Vesiclepedia_1001 24079734 Mus musculus Immunostimulatory activity of murine keratinocyte-derived exosomes. Keratinocytes Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1013 Vesiclepedia_41 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Mast cells Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes EVs
1014 Vesiclepedia_3397 31054213 Homo sapiens Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma Cholangiocarcinoma cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
1015 Vesiclepedia_3072 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1016 Vesiclepedia_144 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes EVs
1017 Vesiclepedia_89 20424270 Rattus norvegicus Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. Basophilic leukemia cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes EVs
1018 Vesiclepedia_911 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1019 Vesiclepedia_1006 23463506 Mus musculus The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1020 Vesiclepedia_1145 23173708 Rattus norvegicus Wnt3a induces exosome secretion from primary cultured rat microglia. Primary microglial cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1021 Vesiclepedia_2657 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1022 Vesiclepedia_3136 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1023 Vesiclepedia_836 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
1024 Vesiclepedia_74 19381331 Homo sapiens High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. Melanoma cells Protein Differential centrifugation Exosomes EVs
1025 Vesiclepedia_22 15940614 Homo sapiens Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape. Colorectal cancer cells Protein Differential centrifugation Exosomes EVs
1026 Vesiclepedia_3113 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1027 Vesiclepedia_3000 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1028 Vesiclepedia_2976 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Iodixanol density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
1029 Vesiclepedia_3405 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Embryonic cells Protein
miRNA
Differential centrifugation
ExoQuick Kit
Exosomes Small EVs
1030 Vesiclepedia_2914 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1031 Vesiclepedia_3080 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1032 Vesiclepedia_518 23585443 Homo sapiens Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Colorectal cancer cells Protein - Exosomes/Membrane vesicles EVs
1033 Vesiclepedia_690 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Bone marrow mesenchymal stem cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1034 Vesiclepedia_2298 29339034 Homo sapiens Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer Pancreatic duct fluid Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1035 Vesiclepedia_1664 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1036 Vesiclepedia_655 28290293 Bos taurus Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
1037 Vesiclepedia_99 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1038 Vesiclepedia_1835 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells miRNA Centrifugation
Filtration
ExoQuick Kit
Exosomes Small EVs
1039 Vesiclepedia_1540 33658392 Homo sapiens Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma Lung cancer cells Protein
miRNA
Minute High-Efficiency Exosome Precipitation Reagent
Filtration
Exosomes Small EVs
1040 Vesiclepedia_1700 34108659 Equus caballus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Serum Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1041 Vesiclepedia_3396 31792209 Homo sapiens Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles Fibroblasts Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1042 Vesiclepedia_3081 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1043 Vesiclepedia_2487 34388111 Homo sapiens miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Monocytic leukemia cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1044 Vesiclepedia_564 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Exosomes EVs
1045 Vesiclepedia_995 24434149 Homo sapiens In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Ovarian cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1046 Vesiclepedia_2231 36648227 Mus musculus Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Macrophage Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1047 Vesiclepedia_429 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine Protein - Exosomes EVs
1048 Vesiclepedia_1570 33738083 Homo sapiens Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1049 Vesiclepedia_1443 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1050 Vesiclepedia_1235 25421927 Heligmosomoides polygyrus Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Heligmosomoides polygyrus miRNA
Protein
Filtration
Ultracentrifugation
Exosomes EVs
1051 Vesiclepedia_1338 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice White adipose tissue miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1052 Vesiclepedia_138 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes EVs
1053 Vesiclepedia_1460 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells miRNA Differential centrifugation

Filtration
Ultracentrifugation
Exosomes Small EVs
1054 Vesiclepedia_88 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Stomach cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1055 Vesiclepedia_2498 34329193 Homo sapiens CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis Breast cancer cells Protein
miRNA
circRNA
Total Exosome Isolation Reagent Exosomes EVs
1056 Vesiclepedia_737 25220352 Mus musculus Surface functionalization of exosomes using click chemistry. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1057 Vesiclepedia_2643 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Mammary epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1058 Vesiclepedia_475 23056502 Homo sapiens Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. Melanoma cells mRNA - Exosomes EVs
1059 Vesiclepedia_2758 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
1060 Vesiclepedia_3275 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1061 Vesiclepedia_1364 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1062 Vesiclepedia_3282 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
1063 Vesiclepedia_965 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1064 Vesiclepedia_469 23029346 Echinostoma caproni Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. Echinostoma caproni Protein - Exosomes/Extracellular vesicles/Microvesicles EVs
1065 Vesiclepedia_271 10903724 Homo sapiens Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface B cells Protein Differential centrifugation Exosomes EVs
1066 Vesiclepedia_54 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
1067 Vesiclepedia_2486 34388111 Homo sapiens miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Monocytic leukemia cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1068 Vesiclepedia_1663 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Mammary cancer-associated fibroblasts Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1069 Vesiclepedia_25 15111327 Homo sapiens Proteomic analysis of exosomes secreted by human mesothelioma cells. Mesothelioma cells Protein Differential centrifugation Exosomes EVs
1070 Vesiclepedia_4 11487543 Homo sapiens Intestinal epithelial cells secrete exosome-like vesicles. Epithelial cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
1071 Vesiclepedia_2757 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
1072 Vesiclepedia_2333 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1073 Vesiclepedia_2646 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1074 Vesiclepedia_1291 19912576 Homo sapiens HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Lymphoblasts Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1075 Vesiclepedia_807 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1076 Vesiclepedia_2917 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1077 Vesiclepedia_699 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1078 Vesiclepedia_1831 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells miRNA Centrifugation
Filtration
ExoQuick Kit
Exosomes Small EVs
1079 Vesiclepedia_1074 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
1080 Vesiclepedia_721 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
1081 Vesiclepedia_1323 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces Protein
Lipid
miRNA
Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
1082 Vesiclepedia_1070 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1083 Vesiclepedia_103 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes EVs
1084 Vesiclepedia_2440 29335551 Homo sapiens Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Liver cancer cells Protein
miRNA
Filtration
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1085 Vesiclepedia_1454 31949130 Homo sapiens circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma Lung cancer cells circRNA Total Exosome Isolation Reagent Exosomes Small EVs
1086 Vesiclepedia_3284 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
1087 Vesiclepedia_975 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes EVs
1088 Vesiclepedia_3413 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph miRNA Differential centrifugation
ExoQuick Kit
Exosomes Small EVs
1089 Vesiclepedia_917 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1090 Vesiclepedia_1089 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes EVs
1091 Vesiclepedia_2438 29335551 Homo sapiens Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Liver cancer cells Protein
miRNA
Filtration
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1092 Vesiclepedia_29 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Serum Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
1093 Vesiclepedia_1499 33982667 Homo sapiens Exosomal circRNA 0001445 promotes glioma progression through miRNA-127-5p/SNX5 pathway Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1094 Vesiclepedia_1200 27780738 Homo sapiens Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Cerebrospinal fluid miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
1095 Vesiclepedia_2606 36581340 Homo sapiens Rab27b, a Regulator of Exosome Secretion, Is Associated With Peritoneal Metastases in Gastric Cancer Gastric cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1096 Vesiclepedia_1185 28042326 Homo sapiens Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model. Synovial mesenchymal stem cells miRNA Differential centrifugation
Filtration
Sucrose density gradient
Exosomes EVs
1097 Vesiclepedia_104 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes EVs
1098 Vesiclepedia_327 20428099 Homo sapiens Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease Urine mRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
1099 Vesiclepedia_457 22723089 Homo sapiens Exosomes as Biomarker Enriched Microvesicles: Characterization of Exosomal Proteins derived from a Panel of Prostate Cell Lines with distinct AR phenotypes. Prostate cancer cells Lipids - Exosomes/Membrane vesicles/Microvesicles EVs
1100 Vesiclepedia_78 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
1101 Vesiclepedia_2632 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1102 Vesiclepedia_554 24009898 Mus musculus Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. Cardiomyocytes mRNA - Exosomes/Extracellular vesicles EVs
1103 Vesiclepedia_679 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Myeloid-derived suppressor cells Protein Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1104 Vesiclepedia_523 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophage Protein - Exosomes EVs
1105 Vesiclepedia_111 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Serum Protein
miRNA
Differential centrifugation
Sucrose density gradient
Immunobeads (CD24)
Exosomes EVs
1106 Vesiclepedia_3015 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1107 Vesiclepedia_777 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1108 Vesiclepedia_652 28290293 Homo sapiens Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Breast milk Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
1109 Vesiclepedia_185 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Follicular fluid Protein
miRNA
Differential centrifugation
ExoQuick
Exosomes EVs
1110 Vesiclepedia_969 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1111 Vesiclepedia_723 25802036 Homo sapiens Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1112 Vesiclepedia_981 25458527 Homo sapiens Benchtop isolation and characterization of functional exosomes by sequential filtration Breast cancer cells Protein Sequential filtration Exosomes EVs
1113 Vesiclepedia_805 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1114 Vesiclepedia_1242 25261722 Homo sapiens Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1115 Vesiclepedia_758 28357077 Mus musculus Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells Osteocytes miRNA Total Exosome Isolation Kit
Differential centrifugation
Exosomes EVs
1116 Vesiclepedia_555 24046871 Homo sapiens Molecular lipidomics of exosomes released by PC-3 prostate cancer cells. Prostate cancer cells Lipids - Exosomes/Microvesicles EVs
1117 Vesiclepedia_1084 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes EVs
1118 Vesiclepedia_2523 34315885 Homo sapiens Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Urine Protein Centrifugation
Ultracentrifugation
Exosomes Small EVs
1119 Vesiclepedia_1826 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Serum miRNA Total Exosome Isolation Kit Exosomes Small EVs
1120 Vesiclepedia_722 25802036 Homo sapiens Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1121 Vesiclepedia_726 25471207 Homo sapiens Intraluminal proteome and peptidome of human urinary extracellular vesicles. Urine Protein Differential centrifugation
Hydrostatic filtration dialysis
Ultrafiltration
Exosomes EVs
1122 Vesiclepedia_901 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1123 Vesiclepedia_528 23767874 Homo sapiens Biochemical and biological characterization of exosomes containing prominin-1/CD133. Melanoma cells Lipids - Exosomes/Microvesicles EVs
1124 Vesiclepedia_1805 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum Protein
miRNA
ExoQuick Kit Exosomes Small EVs
1125 Vesiclepedia_3059 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1126 Vesiclepedia_2672 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1127 Vesiclepedia_141 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes EVs
1128 Vesiclepedia_3010 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1129 Vesiclepedia_2276 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma Protein
miRNA
Differential centrifugation
Polyethylene glycol-based precipitation
Centrifugation
Exosomes Small EVs
1130 Vesiclepedia_565 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Exosomes EVs
1131 Vesiclepedia_445 22418980 Homo sapiens A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Urine Protein - Exosomes EVs
1132 Vesiclepedia_85 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Lung cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1133 Vesiclepedia_833 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
1134 Vesiclepedia_688 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Endometrium-derived mesenchymal stem cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1135 Vesiclepedia_81 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 B cells Protein Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Exosomes EVs
1136 Vesiclepedia_2327 31807237 Homo sapiens Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1137 Vesiclepedia_2444 34489604 Mus musculus Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 Hepatocytes Protein
miRNA
Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1138 Vesiclepedia_3141 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Lung cancer cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1139 Vesiclepedia_2675 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1140 Vesiclepedia_2028 36455873 Homo sapiens Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF Plasma Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1141 Vesiclepedia_1691 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1142 Vesiclepedia_2252 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1143 Vesiclepedia_503 23459212 Bos taurus Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis. Bovine milk Protein - Exosomes EVs
1144 Vesiclepedia_1654 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Glioblastoma cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1145 Vesiclepedia_3021 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1146 Vesiclepedia_546 23983189 Homo sapiens Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. B cells Protein - Exosomes/Extracellular vesicles/Microvesicles EVs
1147 Vesiclepedia_2238 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1148 Vesiclepedia_1665 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Normal mammary epithelial cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1149 Vesiclepedia_1135 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Exosomes EVs
1150 Vesiclepedia_3128 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1151 Vesiclepedia_1263 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1152 Vesiclepedia_1442 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1153 Vesiclepedia_3055 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic duct epithelial cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1154 Vesiclepedia_2338 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Plasma miRNA ExoQuick Kit
Centrifugation
Exosomes Small EVs
1155 Vesiclepedia_1091 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes EVs
1156 Vesiclepedia_2673 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1157 Vesiclepedia_928 25483805 Gallus gallus Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Notochord cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1158 Vesiclepedia_1819 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1159 Vesiclepedia_354 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1160 Vesiclepedia_1701 34108659 Capra hircus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Serum Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1161 Vesiclepedia_1448 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Plasma miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1162 Vesiclepedia_958 26196085 Homo sapiens Identification of prostate cancer biomarkers in urinary exosomes. Urine Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
1163 Vesiclepedia_34 19190083 Homo sapiens Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. Tracheobronchial cells Protein
mRNA
Differential centrifugation
Filtration
Sucrose density gradient
Exosomes EVs
1164 Vesiclepedia_673 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophage Protein Microfiltration
Differential centrifugation
Ultracentrifugation
Exosomes EVs
1165 Vesiclepedia_2998 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1166 Vesiclepedia_440 22251860 Homo sapiens RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls. Serum mRNA - Exosomes/Microvesicles EVs
1167 Vesiclepedia_767 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1168 Vesiclepedia_3018 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1169 Vesiclepedia_30 16446100 Rattus norvegicus Exosomes are released by cultured cortical neurones. Cortical neurons Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
1170 Vesiclepedia_1286 20880880 Homo sapiens Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis. Bronchoalveolar lavage fluid Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1171 Vesiclepedia_3369 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colon cancer cells Protein Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Exosomes Small EVs
1172 Vesiclepedia_2501 34329193 Homo sapiens CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis Breast cancer cells miRNA Total Exosome Isolation Reagent Exosomes EVs
1173 Vesiclepedia_1331 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
1174 Vesiclepedia_2326 31807237 Homo sapiens Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1175 Vesiclepedia_2345 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1176 Vesiclepedia_1282 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1177 Vesiclepedia_825 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
1178 Vesiclepedia_1115 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1179 Vesiclepedia_3536 31608233 Homo sapiens Double-Stranded DNA in Exosomes of Malignant Pleural Effusions as a Novel DNA Source for EGFR Mutation Detection in Lung Adenocarcinoma Pleural effusion dsDNA ExoQuick Kit Exosomes Small EVs
1180 Vesiclepedia_3033 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1181 Vesiclepedia_2659 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1182 Vesiclepedia_432 21751344 Pseudomonas aeruginosa Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa. Pseudomonas aeruginosa Protein - Exosomes/Membrane vesicles EVs
1183 Vesiclepedia_912 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1184 Vesiclepedia_389 18819103 Homo sapiens Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen. Seminal fluid Protein - Exosomes/Prostasomes EVs
1185 Vesiclepedia_87 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Colorectal cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1186 Vesiclepedia_739 25157233 Homo sapiens Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Placenta Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1187 Vesiclepedia_759 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1188 Vesiclepedia_2354 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Stromal vascular fraction miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1189 Vesiclepedia_2633 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1190 Vesiclepedia_810 29932869 Mus musculus Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy Schwann cells miRNA Filtration
Differential centrifugation
Ultracentrifugation
Exosomes EVs
1191 Vesiclepedia_1156 21212511 Homo sapiens Proteomic analysis of two types of exosomes in human whole saliva. Saliva Protein Differential centrifugation
Filtration
Ultracentrifugation
Gel filtration
Exosomes EVs
1192 Vesiclepedia_1456 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells Protein
miRNA
Differential centrifugation

Filtration
Ultracentrifugation
Exosomes Small EVs
1193 Vesiclepedia_2968 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1194 Vesiclepedia_1357 32438511 Homo sapiens Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion Colorectal cancer cells Protein Differential centrifugation
Filtration
OptiPrep density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
1195 Vesiclepedia_1531 33752173 Homo sapiens Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression Plasma miRNA Total Exosome Isolation Kit
Centrifugation
Exosomes Small EVs
1196 Vesiclepedia_1088 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes EVs
1197 Vesiclepedia_49 14582906 Homo sapiens Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. Bronchoalveolar lavage fluid Protein Differential centrifugation
Immunobeads (EpCAM)
Exosomes EVs
1198 Vesiclepedia_1807 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1199 Vesiclepedia_348 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells Protein Differential centrifugation
Filtration
Immunoaffinity (EpCAM)
Ultracentrifugation
Exosomes EVs
1200 Vesiclepedia_782 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1201 Vesiclepedia_76 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Bladder cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
1202 Vesiclepedia_2361 36717543 Rattus norvegicus Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury Schwann cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1203 Vesiclepedia_1457 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells Protein
miRNA
Differential centrifugation

Filtration
Ultracentrifugation
Exosomes Small EVs
1204 Vesiclepedia_968 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1205 Vesiclepedia_1095 24976626 Homo sapiens Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells. Renal proximal tubule cells Protein Differential centrifugation
Ultracentrifugation
Immunoaffinity
Exosomes EVs
1206 Vesiclepedia_2349 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1207 Vesiclepedia_3020 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1208 Vesiclepedia_1260 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1209 Vesiclepedia_2282 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma miRNA Differential centrifugation
Polyethylene glycol-based precipitation
Centrifugation
Exosomes Small EVs
1210 Vesiclepedia_779 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1211 Vesiclepedia_2671 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1212 Vesiclepedia_2692 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage Protein
mRNA
Total Exosome Isolation Reagent Exosomes Small EVs
1213 Vesiclepedia_880 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1214 Vesiclepedia_1329 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces Lipid Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
1215 Vesiclepedia_974 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes EVs
1216 Vesiclepedia_670 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophage Protein Microfiltration
Differential centrifugation
Ultracentrifugation
Exosomes EVs
1217 Vesiclepedia_1343 33159193 Rattus norvegicus Treatment of infarcted heart tissue via the capture and local delivery of circulating exosomes through antibody-conjugated magnetic nanoparticles Serum Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1218 Vesiclepedia_2256 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1219 Vesiclepedia_1199 27883272 Homo sapiens Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. Serum miRNA
Metabolites
ExoQuick Exosomes EVs
1220 Vesiclepedia_2348 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1221 Vesiclepedia_1655 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Glioblastoma cells Protein
mRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1222 Vesiclepedia_3582 31555514 Homo sapiens Liquid biopsies using pleural effusion-derived exosomal DNA in advanced lung adenocarcinoma. Pleural effusion dsDNA-mutated Ultracentrifugation Exosomes Small EVs
1223 Vesiclepedia_2617 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1224 Vesiclepedia_3270 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1225 Vesiclepedia_1837 36408942 Homo sapiens Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1226 Vesiclepedia_2334 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1227 Vesiclepedia_1440 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1228 Vesiclepedia_1252 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1229 Vesiclepedia_793 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1230 Vesiclepedia_3272 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
1231 Vesiclepedia_1458 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Mammary epithelial cells miRNA Differential centrifugation

Filtration
Ultracentrifugation
Exosomes Small EVs
1232 Vesiclepedia_2624 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1233 Vesiclepedia_886 25102470 Homo sapiens Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1234 Vesiclepedia_3053 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Plasma miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
1235 Vesiclepedia_2475 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1236 Vesiclepedia_3407 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph Protein Differential centrifugation
ExoQuick Kit
Exosomes Small EVs
1237 Vesiclepedia_3078 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1238 Vesiclepedia_2986 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1239 Vesiclepedia_2001 34112803 Homo sapiens Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Plasma Protein Size exclusion chromatography
Centrifugal ultrafiltration
Exosomes Small EVs
1240 Vesiclepedia_1127 24295599 Mus musculus Exosomes from myeloid-derived suppressor cells carry biologically active proteins. Myeloid-derived suppressor cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1241 Vesiclepedia_1142 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells Protein Differential centrifugation
Ultracentrifugation
Filtration
ExoQuick
Exosomes EVs
1242 Vesiclepedia_1359 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1243 Vesiclepedia_1340 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice Liver miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1244 Vesiclepedia_3274 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
1245 Vesiclepedia_3032 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1246 Vesiclepedia_2912 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1247 Vesiclepedia_837 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
1248 Vesiclepedia_137 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes EVs
1249 Vesiclepedia_2245 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1250 Vesiclepedia_3139 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Plasma Protein
miRNA
ExoQuick Kit Exosomes EVs
1251 Vesiclepedia_1202 27780738 Homo sapiens Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Cerebrospinal fluid miRNA Differential centrifugation
Ultracentrifugation
Exosomes EVs
1252 Vesiclepedia_785 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1253 Vesiclepedia_1117 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1254 Vesiclepedia_1822 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1255 Vesiclepedia_2616 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1256 Vesiclepedia_1446 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1257 Vesiclepedia_1047 28725021 Bos taurus Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1258 Vesiclepedia_2299 29339034 Homo sapiens Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer Pancreatic duct fluid Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1259 Vesiclepedia_3142 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Lung epithelial cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1260 Vesiclepedia_1550 33638284 Canis lupus familiaris Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition Kidney cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1261 Vesiclepedia_660 29964051 Homo sapiens Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway Adipose tissue-derived stem cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1262 Vesiclepedia_2340 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1263 Vesiclepedia_1453 31949130 Homo sapiens circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma Lung cancer cells circRNA Total Exosome Isolation Reagent Exosomes Small EVs
1264 Vesiclepedia_977 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes EVs
1265 Vesiclepedia_2466 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1266 Vesiclepedia_2622 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1267 Vesiclepedia_1673 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1268 Vesiclepedia_1268 24218614 Homo sapiens Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1269 Vesiclepedia_2765 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Tangential flow filtration Exosomes Small EVs
1270 Vesiclepedia_3279 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
1271 Vesiclepedia_1215 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1272 Vesiclepedia_1143 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells Protein Differential centrifugation
Ultracentrifugation
Filtration
ExoQuick
Exosomes EVs
1273 Vesiclepedia_3114 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Podocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1274 Vesiclepedia_28 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Glioma cells Protein Differential centrifugation
Sucrose density gradient
Exosomes EVs
1275 Vesiclepedia_2003 34112803 Mus musculus Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Centrifugal ultrafiltration
Exosomes Small EVs
1276 Vesiclepedia_21 19837982 Homo sapiens Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215. Colorectal cancer cells Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes EVs
1277 Vesiclepedia_1132 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Exosomes EVs
1278 Vesiclepedia_1682 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1279 Vesiclepedia_1541 33658392 Homo sapiens Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma Lung cancer cells Protein
miRNA
Minute High-Efficiency Exosome Precipitation Reagent
Filtration
Exosomes Small EVs
1280 Vesiclepedia_3280 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Total Exosome Isolation Reagent
Exosomes EVs
1281 Vesiclepedia_2243 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1282 Vesiclepedia_698 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1283 Vesiclepedia_1054 29115712 Mus musculus Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1284 Vesiclepedia_1243 25261722 Homo sapiens Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1285 Vesiclepedia_1459 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells miRNA Differential centrifugation

Filtration
Ultracentrifugation
Exosomes Small EVs
1286 Vesiclepedia_1913 36270983 Mus musculus NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancer Lung epithelial cells Protein Centrifugation
Exosome Isolation Reagent
Exosomes Small EVs
1287 Vesiclepedia_3138 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1288 Vesiclepedia_1677 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1289 Vesiclepedia_2762 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
1290 Vesiclepedia_1277 23344851 Rattus norvegicus Urinary exosomes and diabetic nephropathy: a proteomic approach. Urine Protein Ultracentrifugation Exosomes EVs
1291 Vesiclepedia_2913 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Plasma Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1292 Vesiclepedia_3149 29438363 Homo sapiens CD9-positive exosomes from cancer-associated fibroblasts stimulate the migration ability of scirrhous-type gastric cancer cells Fibroblasts Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1293 Vesiclepedia_1257 24400796 Homo sapiens Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Retinal pigment epithelial cells Protein ExoQuick Exosomes EVs
1294 Vesiclepedia_2239 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1295 Vesiclepedia_1071 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1296 Vesiclepedia_1817 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1297 Vesiclepedia_2775 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine Protein Filtration
Exosome detection via ultrafast-isolation system (EXODUS)
Exosomes Small EVs
1298 Vesiclepedia_2656 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1299 Vesiclepedia_1098 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. adipocytes Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
1300 Vesiclepedia_1685 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1301 Vesiclepedia_1445 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells miRNA Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1302 Vesiclepedia_2281 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma miRNA Differential centrifugation
Polyethylene glycol-based precipitation
Centrifugation
Exosomes Small EVs
1303 Vesiclepedia_1337 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice White adipose tissue miRNA Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1304 Vesiclepedia_663 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
1305 Vesiclepedia_914 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1306 Vesiclepedia_1839 36408942 Rattus norvegicus Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Bone marrow mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1307 Vesiclepedia_1147 23173708 Rattus norvegicus Wnt3a induces exosome secretion from primary cultured rat microglia. Primary microglial cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1308 Vesiclepedia_3001 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1309 Vesiclepedia_1245 25167841 Homo sapiens Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Serum Protein CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips Exosomes EVs
1310 Vesiclepedia_391 19327352 Bos taurus Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes. Serum Protein - Exosomes EVs
1311 Vesiclepedia_1158 20662102 Mus musculus Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages. Macrophage Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1312 Vesiclepedia_820 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
1313 Vesiclepedia_814 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes EVs
1314 Vesiclepedia_2464 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1315 Vesiclepedia_736 25285581 Mus musculus Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells. Myeloid-derived suppressor cells Protein Differential centrifugation
Ultracentrifugation
Exosomes EVs
1316 Vesiclepedia_2465 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum miRNA Centrifugation
Filtration
Ultracentrifugation
Exosomes Small EVs
1317 Vesiclepedia_707 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes EVs
1318 Vesiclepedia_110 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Ascites Protein
miRNA
Differential centrifugation
Sucrose density gradient
Exosomes EVs
1319 Vesiclepedia_2696 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage mRNA Total Exosome Isolation Reagent Exosomes Small EVs
1320 Vesiclepedia_1027 24211404 Homo sapiens Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis. Urine Protein Ultracentrifugation
ExoQuick
Exosomes EVs
1321 Vesiclepedia_794 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1322 Vesiclepedia_485 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Metacyclic trypomastigotes Protein - Exosomes/Extracellular vesicles/Ectosomes EVs
1323 Vesiclepedia_665 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid miRNA Differential centrifugation
Ultracentrifugation
Filtration
Exosomes EVs
1324 Vesiclepedia_768 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1325 Vesiclepedia_3121 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Kidney cells Protein Differential centrifugation
Filtration
Sucrose density gradient centrifugation
Ultracentrifugation
Exosomes Small EVs
1326 Vesiclepedia_2674 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1327 Vesiclepedia_2230 36648227 Mus musculus Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Macrophage Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1328 Vesiclepedia_2984 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1329 Vesiclepedia_1672 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Exosomes Small EVs
1330 Vesiclepedia_804 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes EVs
1331 Vesiclepedia_3278 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes Small EVs
1332 Vesiclepedia_2652 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells Protein Differential centrifugation
Filtration
Immunoaffinity capture
Ultracentrifugation
Exosomes Small EVs
1333 Vesiclepedia_1543 33767144 Homo sapiens Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells Cervical cancer cells Protein Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Exosomes Small EVs
1334 Vesiclepedia_335 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Exosomes EVs